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The map label for this gene is blh [H]

Identifier: 209549863

GI number: 209549863

Start: 2333382

End: 2334662

Strand: Reverse

Name: blh [H]

Synonym: Rleg2_2276

Alternate gene names: 209549863

Gene position: 2334662-2333382 (Counterclockwise)

Preceding gene: 209549865

Following gene: 209549862

Centisome position: 51.45

GC content: 64.64

Gene sequence:

>1281_bases
ATGACATCCGTAAGGGTCAATGAGCTGATATCGGTGGCGGGGCAGCCCGATGCCGCCGGTTTTGCTGCTTTTGCGGCAGA
CGGTTTTGCCGGCGTCATCAATGCGCGGCCGGATGGCGAGGAGCCGGGGCAGCCGGGCGATGCGGCGGAAAAGGCTTCTG
CCGCCGCCGCGGGGCTCGCCTACAGCTTCGTGCCGGTGAAAGGGGCCGAGATCACCGAGGCCGATATCCGCGCCTTCCAG
AGGGCGATGATGCAAGCGAAGGGGCCGGTCGTCGCTCATTGCAAGAGCGGCACGCGGGCGCTGACGCTCTATGCGCTCGG
AGAGGTGCTCGACGGGCGGATGCAGCCCGGGGACGTCGAGGCCTTCGGTCAAAACCTCGGCTTCGATCTTGCCGGCGCAC
GCCGCTGGCTGGAAAAGCGGGCAGGGCAGACGGCTGTCGTGAAGGCCTTCTTCGAACCCCGCACCTGCAGTGTGCAATAT
GTCGTTTCAGACCCGGTCACGAAACGCTGCGCCATCATCGACCCGGTGCTCGATTTCGACGAGATGTCGGGTGCGACGGG
AACGACCAATGCCGACGCCATCCTCGCGCATATCGACAGCGAAGGGCTGACGGTCGAGTGGGTCCTCGACACGCATCCGC
ATGCCGATCATTTCTCCGCCGCGCACTATCTCAAGGGAAAGACCGGCGCGCCGACAGCGATCGGCGCCCATGTCACCGAG
GTCCAGCTGCTCTGGAAGGAAATCTACAACTGGCCGGCACTCGAAACCGACGGCTCGCAATGGAACCGGCTGTTTGCCGA
GGGCGACACTTTCGAGATCGGCGGGCTTGAAGCCCGTGTGATGTTCTCGCCCGGCCATACGCTTGCCTCGGTGACCTATG
TGATCGGTGACGCCGCCTTCGTGCACGACACCGTATTCACCCCGGATTCCGGCACGGCGCGCACTGATTTTCCCGGCGGC
AGCGCCAGCGCCCTCTGGCACTCGATCCAGGCCATCCTGTCGCTGCCCGAGGAGACCCGGCTCTTTTCCGGCCACGACTA
TCAGCCTGGCGGTCGCCATCCCCGCTGGGAAAGCACGGTGACCGCCCAGAAGACCGCCAATCCGCATATATCGGGTATCG
ATGAGGCCGGCTTTGTGACGCTGCGCCAGGCGCGCGACCGTACGCTACCGAAACCGAAGCTGATGCTGCACGCGCTACAG
GTGAATATTCGGGGCGGACGGCTGCCCGAGCCGGAGGAGAACGGCCGGCGCTATCTGAAAATCCCGCTGGATGCGTTGTA
G

Upstream 100 bases:

>100_bases
GGGGCGGCGCCAAGCGACTATTCTTGCGCTCGGCAATATACTTGTGAGATTGTACCGATATACATGCGATACTGTCGATG
CAGGCAGCGCGGGGGCTTCG

Downstream 100 bases:

>100_bases
CAACGCAGGGAGCAGCGTTGCGGCGCGTGCTTCGAGGCTTCGCCCTCCCGGGCTGCGCACCTCAGCATGAGGGAGGTCGG
AGGGTGCCGCACCCACGACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTSVRVNELISVAGQPDAAGFAAFAADGFAGVINARPDGEEPGQPGDAAEKASAAAAGLAYSFVPVKGAEITEADIRAFQ
RAMMQAKGPVVAHCKSGTRALTLYALGEVLDGRMQPGDVEAFGQNLGFDLAGARRWLEKRAGQTAVVKAFFEPRTCSVQY
VVSDPVTKRCAIIDPVLDFDEMSGATGTTNADAILAHIDSEGLTVEWVLDTHPHADHFSAAHYLKGKTGAPTAIGAHVTE
VQLLWKEIYNWPALETDGSQWNRLFAEGDTFEIGGLEARVMFSPGHTLASVTYVIGDAAFVHDTVFTPDSGTARTDFPGG
SASALWHSIQAILSLPEETRLFSGHDYQPGGRHPRWESTVTAQKTANPHISGIDEAGFVTLRQARDRTLPKPKLMLHALQ
VNIRGGRLPEPEENGRRYLKIPLDAL

Sequences:

>Translated_426_residues
MTSVRVNELISVAGQPDAAGFAAFAADGFAGVINARPDGEEPGQPGDAAEKASAAAAGLAYSFVPVKGAEITEADIRAFQ
RAMMQAKGPVVAHCKSGTRALTLYALGEVLDGRMQPGDVEAFGQNLGFDLAGARRWLEKRAGQTAVVKAFFEPRTCSVQY
VVSDPVTKRCAIIDPVLDFDEMSGATGTTNADAILAHIDSEGLTVEWVLDTHPHADHFSAAHYLKGKTGAPTAIGAHVTE
VQLLWKEIYNWPALETDGSQWNRLFAEGDTFEIGGLEARVMFSPGHTLASVTYVIGDAAFVHDTVFTPDSGTARTDFPGG
SASALWHSIQAILSLPEETRLFSGHDYQPGGRHPRWESTVTAQKTANPHISGIDEAGFVTLRQARDRTLPKPKLMLHALQ
VNIRGGRLPEPEENGRRYLKIPLDAL
>Mature_425_residues
TSVRVNELISVAGQPDAAGFAAFAADGFAGVINARPDGEEPGQPGDAAEKASAAAAGLAYSFVPVKGAEITEADIRAFQR
AMMQAKGPVVAHCKSGTRALTLYALGEVLDGRMQPGDVEAFGQNLGFDLAGARRWLEKRAGQTAVVKAFFEPRTCSVQYV
VSDPVTKRCAIIDPVLDFDEMSGATGTTNADAILAHIDSEGLTVEWVLDTHPHADHFSAAHYLKGKTGAPTAIGAHVTEV
QLLWKEIYNWPALETDGSQWNRLFAEGDTFEIGGLEARVMFSPGHTLASVTYVIGDAAFVHDTVFTPDSGTARTDFPGGS
ASALWHSIQAILSLPEETRLFSGHDYQPGGRHPRWESTVTAQKTANPHISGIDEAGFVTLRQARDRTLPKPKLMLHALQV
NIRGGRLPEPEENGRRYLKIPLDAL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=281, Percent_Identity=29.5373665480427, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17538952, Length=265, Percent_Identity=27.1698113207547, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330176, Length=269, Percent_Identity=27.8810408921933, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 45709; Mature: 45578

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVRVNELISVAGQPDAAGFAAFAADGFAGVINARPDGEEPGQPGDAAEKASAAAAGLA
CCCCCHHHHHHHCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHE
YSFVPVKGAEITEADIRAFQRAMMQAKGPVVAHCKSGTRALTLYALGEVLDGRMQPGDVE
EEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEEHEEHHHHHCCCCCCCCHH
AFGQNLGFDLAGARRWLEKRAGQTAVVKAFFEPRTCSVQYVVSDPVTKRCAIIDPVLDFD
HHHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEECCCCCCHHEEECCCCCHH
EMSGATGTTNADAILAHIDSEGLTVEWVLDTHPHADHFSAAHYLKGKTGAPTAIGAHVTE
HHCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHCCHHHH
VQLLWKEIYNWPALETDGSQWNRLFAEGDTFEIGGLEARVMFSPGHTLASVTYVIGDAAF
HHHHHHHHHCCCCCCCCCHHHHHHEECCCEEEECCEEEEEEECCCCCHHEEHHHHCCHHH
VHDTVFTPDSGTARTDFPGGSASALWHSIQAILSLPEETRLFSGHDYQPGGRHPRWESTV
HCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCE
TAQKTANPHISGIDEAGFVTLRQARDRTLPKPKLMLHALQVNIRGGRLPEPEENGRRYLK
EEHHCCCCCCCCCCCCCEEEEEHHHCCCCCCHHHEEEEEEEEECCCCCCCCCCCCCEEEE
IPLDAL
EECCCC
>Mature Secondary Structure 
TSVRVNELISVAGQPDAAGFAAFAADGFAGVINARPDGEEPGQPGDAAEKASAAAAGLA
CCCCHHHHHHHCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHE
YSFVPVKGAEITEADIRAFQRAMMQAKGPVVAHCKSGTRALTLYALGEVLDGRMQPGDVE
EEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEEHEEHHHHHCCCCCCCCHH
AFGQNLGFDLAGARRWLEKRAGQTAVVKAFFEPRTCSVQYVVSDPVTKRCAIIDPVLDFD
HHHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEECCCCCCHHEEECCCCCHH
EMSGATGTTNADAILAHIDSEGLTVEWVLDTHPHADHFSAAHYLKGKTGAPTAIGAHVTE
HHCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHCCHHHH
VQLLWKEIYNWPALETDGSQWNRLFAEGDTFEIGGLEARVMFSPGHTLASVTYVIGDAAF
HHHHHHHHHCCCCCCCCCHHHHHHEECCCEEEECCEEEEEEECCCCCHHEEHHHHCCHHH
VHDTVFTPDSGTARTDFPGGSASALWHSIQAILSLPEETRLFSGHDYQPGGRHPRWESTV
HCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCE
TAQKTANPHISGIDEAGFVTLRQARDRTLPKPKLMLHALQVNIRGGRLPEPEENGRRYLK
EEHHCCCCCCCCCCCCCEEEEEHHHCCCCCCHHHEEEEEEEEECCCCCCCCCCCCCEEEE
IPLDAL
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]