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The map label for this gene is tktB [C]

Identifier: 209549626

GI number: 209549626

Start: 2095172

End: 2095981

Strand: Reverse

Name: tktB [C]

Synonym: Rleg2_2033

Alternate gene names: 209549626

Gene position: 2095981-2095172 (Counterclockwise)

Preceding gene: 209549632

Following gene: 209549625

Centisome position: 46.19

GC content: 58.02

Gene sequence:

>810_bases
ATGGATACGATAGAACTTGAGCGCATCGCCCGCGAGATCCGATTGCGCGATCTGCAGGCGGTCTTTGAAGCGGGCGCCGG
CCATATTGGCGGGGAGATGTCGGTCATCGACATTTTGGCGGCGCTCTATTTTCGTGTCCTGAATGTCTGGCCGGATCAGC
CTGGACATCCCGACCGCGACAGGTTCGTCCTTTCAAAGGGACATACGGCGTGTGCTCTCTATGTGACGCTGGCAAAACGC
GGCTTCATTCCGGAGGAGGAGGTCTCCACCTTTCTGCAGCCGCATTCGAGGCTGAACGGGCATCCGAATTGCAACAAGGT
TCCCGGCGTCGAAACGAATACCGGTCCGCTGGGCCACGGTCTTCCGGTGGCAGTCGGAATGGCGAAGGCCGCCAAGCTCT
CAGGCGCGAAATATCATACCTACGTCGTCACCGGCGACGGTGAGATGCAGGAGGGTTCGAACTGGGAAGCGATCATGGCG
GCCGCTCAGTTCAAACTCGACAACTTGACCCTGGTCATCGATCACAACAGGTTCCAGCAGGGTGCGGCGCTCGCCGAAAC
CAATGATCTCGCTCCGCTTCGTCCGAAGCTCGAGGCCTTCGATTGGGAGGTCACCGAGATCAACGGGAACACGATGAGCG
AAGTCGTTCCGGCTCTCGAACACCGGGGATCAAGACCTCATTGCATCGTCGCCCATACCAACAAGGGCCACGGAATATCG
TTCATGCAAGACCGGGTCGACTGGCACCACAAGGTGCCGAACAAGGAACAGTACGAAATTGCATTGGCAGAATTGTCGGA
GGCACTCTAA

Upstream 100 bases:

>100_bases
TCGGGCCTTCGCTACCGCAGCATGGTATAAGGGGCTTGACTAATCGGCTTCTTGTGCAAAAATATTGATAAGTGAATATT
TATGCACACATGAGGAACCC

Downstream 100 bases:

>100_bases
ATGAACGCGTCAGTAAACCCACCCAAGCTCTATGATTGCCGCGACGCATTCGCCTCTACGCTTGAACGGTTGGCAGCCGA
AAACGACACGATCGTTGCCG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MDTIELERIAREIRLRDLQAVFEAGAGHIGGEMSVIDILAALYFRVLNVWPDQPGHPDRDRFVLSKGHTACALYVTLAKR
GFIPEEEVSTFLQPHSRLNGHPNCNKVPGVETNTGPLGHGLPVAVGMAKAAKLSGAKYHTYVVTGDGEMQEGSNWEAIMA
AAQFKLDNLTLVIDHNRFQQGAALAETNDLAPLRPKLEAFDWEVTEINGNTMSEVVPALEHRGSRPHCIVAHTNKGHGIS
FMQDRVDWHHKVPNKEQYEIALAELSEAL

Sequences:

>Translated_269_residues
MDTIELERIAREIRLRDLQAVFEAGAGHIGGEMSVIDILAALYFRVLNVWPDQPGHPDRDRFVLSKGHTACALYVTLAKR
GFIPEEEVSTFLQPHSRLNGHPNCNKVPGVETNTGPLGHGLPVAVGMAKAAKLSGAKYHTYVVTGDGEMQEGSNWEAIMA
AAQFKLDNLTLVIDHNRFQQGAALAETNDLAPLRPKLEAFDWEVTEINGNTMSEVVPALEHRGSRPHCIVAHTNKGHGIS
FMQDRVDWHHKVPNKEQYEIALAELSEAL
>Mature_269_residues
MDTIELERIAREIRLRDLQAVFEAGAGHIGGEMSVIDILAALYFRVLNVWPDQPGHPDRDRFVLSKGHTACALYVTLAKR
GFIPEEEVSTFLQPHSRLNGHPNCNKVPGVETNTGPLGHGLPVAVGMAKAAKLSGAKYHTYVVTGDGEMQEGSNWEAIMA
AAQFKLDNLTLVIDHNRFQQGAALAETNDLAPLRPKLEAFDWEVTEINGNTMSEVVPALEHRGSRPHCIVAHTNKGHGIS
FMQDRVDWHHKVPNKEQYEIALAELSEAL

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=261, Percent_Identity=36.3984674329502, Blast_Score=167, Evalue=7e-42,
Organism=Homo sapiens, GI4507521, Length=261, Percent_Identity=36.3984674329502, Blast_Score=167, Evalue=7e-42,
Organism=Homo sapiens, GI133778974, Length=267, Percent_Identity=34.0823970037453, Blast_Score=150, Evalue=9e-37,
Organism=Homo sapiens, GI225637459, Length=267, Percent_Identity=27.7153558052434, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI225637461, Length=236, Percent_Identity=28.3898305084746, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI225637463, Length=234, Percent_Identity=28.2051282051282, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1788808, Length=278, Percent_Identity=32.7338129496403, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI48994911, Length=248, Percent_Identity=35.0806451612903, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17539652, Length=251, Percent_Identity=33.4661354581673, Blast_Score=147, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6325331, Length=251, Percent_Identity=33.0677290836653, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319593, Length=251, Percent_Identity=31.8725099601594, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI45551847, Length=251, Percent_Identity=34.6613545816733, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI45550715, Length=251, Percent_Identity=34.6613545816733, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24645119, Length=217, Percent_Identity=36.405529953917, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24666278, Length=264, Percent_Identity=32.5757575757576, Blast_Score=137, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 29694; Mature: 29694

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTIELERIAREIRLRDLQAVFEAGAGHIGGEMSVIDILAALYFRVLNVWPDQPGHPDRD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RFVLSKGHTACALYVTLAKRGFIPEEEVSTFLQPHSRLNGHPNCNKVPGVETNTGPLGHG
CEEEECCCCEEEHHEEHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
LPVAVGMAKAAKLSGAKYHTYVVTGDGEMQEGSNWEAIMAAAQFKLDNLTLVIDHNRFQQ
CHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHEEECCEEEEEECCCCCC
GAALAETNDLAPLRPKLEAFDWEVTEINGNTMSEVVPALEHRGSRPHCIVAHTNKGHGIS
CCCCCCCCCCCCCCCCHHHCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHH
FMQDRVDWHHKVPNKEQYEIALAELSEAL
HHHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTIELERIAREIRLRDLQAVFEAGAGHIGGEMSVIDILAALYFRVLNVWPDQPGHPDRD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RFVLSKGHTACALYVTLAKRGFIPEEEVSTFLQPHSRLNGHPNCNKVPGVETNTGPLGHG
CEEEECCCCEEEHHEEHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
LPVAVGMAKAAKLSGAKYHTYVVTGDGEMQEGSNWEAIMAAAQFKLDNLTLVIDHNRFQQ
CHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHEEECCEEEEEECCCCCC
GAALAETNDLAPLRPKLEAFDWEVTEINGNTMSEVVPALEHRGSRPHCIVAHTNKGHGIS
CCCCCCCCCCCCCCCCHHHCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHH
FMQDRVDWHHKVPNKEQYEIALAELSEAL
HHHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]