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The map label for this gene is folB [H]

Identifier: 209549564

GI number: 209549564

Start: 2017965

End: 2018330

Strand: Reverse

Name: folB [H]

Synonym: Rleg2_1970

Alternate gene names: 209549564

Gene position: 2018330-2017965 (Counterclockwise)

Preceding gene: 209549565

Following gene: 209549563

Centisome position: 44.48

GC content: 61.75

Gene sequence:

>366_bases
ATGACCACCTACACGATCACGCTGCAGAACTGCGCCTTCTTTGCGCGCCACGGCGTTCATGACGAGGAGGAATTCCTCGG
CCAGCGCTTCTTCGTCGATGCCGAGCTGGATGTCGTTGCCGGCGAGGCGCTGAAAAGCGACTCGATCGACGATACCGTCA
ATTACGGCATCGCCTTCACGGTGATCGAGGGGATCGTCACCGGCAAGCGCCGTTACCTGATCGAGGCGCTGGCGCTCGAT
ATCGCCAAGGGGCTCTGCGAGACATTCCCGCAGGTCCGGCGGGCAAAGATCACGGTGCGCAAGCCGAATGCGCCGGTGCC
CGGCGTGCTCGATTTCGTGCAGGTGAGCGTTGAACACTTTGCCTGA

Upstream 100 bases:

>100_bases
CGGTTTTCCGGGTGCACAATGTCGCAATCAACAGGGATGCGCTTGATATCGCCGATGCTATGCTGAATGCGCGCCAGGAA
TTCGAGAGGAAGCGGCCGAC

Downstream 100 bases:

>100_bases
GACCGCAATGCGATCGGCCACACTCGGCCTCGGCGGCAATATCGGCGATCCCGTCAAAGCGATGGCCGCCGCGCTGCAGC
GGCTGGACGGACGAGATGAC

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MTTYTITLQNCAFFARHGVHDEEEFLGQRFFVDAELDVVAGEALKSDSIDDTVNYGIAFTVIEGIVTGKRRYLIEALALD
IAKGLCETFPQVRRAKITVRKPNAPVPGVLDFVQVSVEHFA

Sequences:

>Translated_121_residues
MTTYTITLQNCAFFARHGVHDEEEFLGQRFFVDAELDVVAGEALKSDSIDDTVNYGIAFTVIEGIVTGKRRYLIEALALD
IAKGLCETFPQVRRAKITVRKPNAPVPGVLDFVQVSVEHFA
>Mature_120_residues
TTYTITLQNCAFFARHGVHDEEEFLGQRFFVDAELDVVAGEALKSDSIDDTVNYGIAFTVIEGIVTGKRRYLIEALALDI
AKGLCETFPQVRRAKITVRKPNAPVPGVLDFVQVSVEHFA

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13434; Mature: 13302

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYTITLQNCAFFARHGVHDEEEFLGQRFFVDAELDVVAGEALKSDSIDDTVNYGIAFT
CCEEEEEHHHHHHHHHCCCCCHHHHCCHHEEECCCHHEEECCHHCCCCCCCHHHCCHHHH
VIEGIVTGKRRYLIEALALDIAKGLCETFPQVRRAKITVRKPNAPVPGVLDFVQVSVEHF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHC
A
C
>Mature Secondary Structure 
TTYTITLQNCAFFARHGVHDEEEFLGQRFFVDAELDVVAGEALKSDSIDDTVNYGIAFT
CEEEEEHHHHHHHHHCCCCCHHHHCCHHEEECCCHHEEECCHHCCCCCCCHHHCCHHHH
VIEGIVTGKRRYLIEALALDIAKGLCETFPQVRRAKITVRKPNAPVPGVLDFVQVSVEHF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9168622 [H]