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The map label for this gene is ttuD [H]

Identifier: 209549064

GI number: 209549064

Start: 1488135

End: 1489409

Strand: Reverse

Name: ttuD [H]

Synonym: Rleg2_1461

Alternate gene names: 209549064

Gene position: 1489409-1488135 (Counterclockwise)

Preceding gene: 209549066

Following gene: 209549058

Centisome position: 32.82

GC content: 66.04

Gene sequence:

>1275_bases
ATGACGATAAGCGCTCCCCGCGATTTCCTGAAAAGCCTGTTCGATGCGGCGGTTCGCGCCGCTGATCCGCTGACCGGCAT
CAAGGCAAACCTGCCTGATCGGCCGAAGGGAAAGACCGTGGTGATCGGTGCCGGCAAGGGTGCCGCGCAGATGGCGCGGG
CGCTCGAAAGCGTCTGGGACGGGCCGCTCGACGGTCTAGTGGTCACACGCTACGGCTATGGCTGCGACACACGCGACATC
GCGATCATCGAGGCTGCCCATCCTGTTCCCGATGCGGCGGGACGTGCCGCGGCAAGTCGGCTGGTGGAGACGGTGAGCGG
ACTGACGGAAGACGATCTGGTGATCGCGCTGATCTGCGGTGGCGGCTCGGCGCTGCTGCCCGCCCCGCCGGTGGGGCTGA
CCCTCGAAGACGAGATTGCCCTCAACGAAATGCTGCTTGCCTCGGGCGCGCCGATCTCGGCGATGAACGTCGTGCGCAAG
CATCTCTCGACCATCAAAGGCGGCAGACTTGCGGCGGCAACCAGAGCAAGGGTCGTCAGCCTGATCGTCTCCGATATTCC
CGGCGACAATCCGGCCCACGTCGCCTCCGGGCCGACCGTGCCTGATGGTTCGACGCGGCACGATGCGCTTGAGATCGTCA
AGCAATATGGATTGCAGCTGCCGCAGGCAGCCCTCGACCATCTGAACTCAGCCAAGGCCGATGCACCGCGGCCGGACGAT
CCGGTGTTTTTACGCCACGCGCATCACATCATTGCCTCTGCCGGCGTGTCGCTGGAGGCGGCCGCCGCCCTGGCGAAGTC
GCAGGGGATCGAGCCCGCCATCCTTTCGGATGCGATCGAGGGAGAATCGCGCGACGTGGCGCTGGTGCATGCGGCAATCG
CCCGTGAGGTGCTCGGCCGGAACAGGCCGTTTCCGAAGCCGGTCGTCATCCTGTCCGGCGGCGAGACAACGGTGACGCTC
CGCGCCAAGGGCGCCAAGGGCGGCAAGGGCGGGCGCAACGGCGAATTCGCGCTCGCCATGGCGCTTGCGATCGACGGACA
GGAGGGCATTCATCTCCTTGCCGCCGACACGGACGGGATCGACGGCTCGGAGGATAATGCCGGCGCCTTTGCCGATGGCG
GCACGGTCAAGCGCCTGCGCGCCGCCGGGCTCGATCCGCGCCGGCTGCTCGACGGCAATGACAGTTATTCAGGCTTTGCA
GCCGTCGGCGATCTCTTCGAAACGGGGCCGACCGGCACCAACGTCAATGATTTCAGGGCCATCCTGATCCGTTAG

Upstream 100 bases:

>100_bases
CCACAACCGTCACACTGCCGCGTCTTCGACCTTGACGCCGGCACGGGGATGCGTCGACAGTCGGCATCACGTTCGACACT
CCAGGCAGCAGAGACCACCG

Downstream 100 bases:

>100_bases
CCGGCGGCGGATCAGGTCTCGATCCGCCCCTGCCCGACCAGCCAGTCAACCGATTCCTGCACCGCCTGCAGCGACGTATA
TCTCGGCGCATAGCCGAGCA

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTISAPRDFLKSLFDAAVRAADPLTGIKANLPDRPKGKTVVIGAGKGAAQMARALESVWDGPLDGLVVTRYGYGCDTRDI
AIIEAAHPVPDAAGRAAASRLVETVSGLTEDDLVIALICGGGSALLPAPPVGLTLEDEIALNEMLLASGAPISAMNVVRK
HLSTIKGGRLAAATRARVVSLIVSDIPGDNPAHVASGPTVPDGSTRHDALEIVKQYGLQLPQAALDHLNSAKADAPRPDD
PVFLRHAHHIIASAGVSLEAAAALAKSQGIEPAILSDAIEGESRDVALVHAAIAREVLGRNRPFPKPVVILSGGETTVTL
RAKGAKGGKGGRNGEFALAMALAIDGQEGIHLLAADTDGIDGSEDNAGAFADGGTVKRLRAAGLDPRRLLDGNDSYSGFA
AVGDLFETGPTGTNVNDFRAILIR

Sequences:

>Translated_424_residues
MTISAPRDFLKSLFDAAVRAADPLTGIKANLPDRPKGKTVVIGAGKGAAQMARALESVWDGPLDGLVVTRYGYGCDTRDI
AIIEAAHPVPDAAGRAAASRLVETVSGLTEDDLVIALICGGGSALLPAPPVGLTLEDEIALNEMLLASGAPISAMNVVRK
HLSTIKGGRLAAATRARVVSLIVSDIPGDNPAHVASGPTVPDGSTRHDALEIVKQYGLQLPQAALDHLNSAKADAPRPDD
PVFLRHAHHIIASAGVSLEAAAALAKSQGIEPAILSDAIEGESRDVALVHAAIAREVLGRNRPFPKPVVILSGGETTVTL
RAKGAKGGKGGRNGEFALAMALAIDGQEGIHLLAADTDGIDGSEDNAGAFADGGTVKRLRAAGLDPRRLLDGNDSYSGFA
AVGDLFETGPTGTNVNDFRAILIR
>Mature_423_residues
TISAPRDFLKSLFDAAVRAADPLTGIKANLPDRPKGKTVVIGAGKGAAQMARALESVWDGPLDGLVVTRYGYGCDTRDIA
IIEAAHPVPDAAGRAAASRLVETVSGLTEDDLVIALICGGGSALLPAPPVGLTLEDEIALNEMLLASGAPISAMNVVRKH
LSTIKGGRLAAATRARVVSLIVSDIPGDNPAHVASGPTVPDGSTRHDALEIVKQYGLQLPQAALDHLNSAKADAPRPDDP
VFLRHAHHIIASAGVSLEAAAALAKSQGIEPAILSDAIEGESRDVALVHAAIAREVLGRNRPFPKPVVILSGGETTVTLR
AKGAKGGKGGRNGEFALAMALAIDGQEGIHLLAADTDGIDGSEDNAGAFADGGTVKRLRAAGLDPRRLLDGNDSYSGFAA
VGDLFETGPTGTNVNDFRAILIR

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=385, Percent_Identity=34.8051948051948, Blast_Score=166, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI193205461, Length=463, Percent_Identity=28.7257019438445, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI19920578, Length=387, Percent_Identity=29.9741602067183, Blast_Score=125, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 43564; Mature: 43433

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISAPRDFLKSLFDAAVRAADPLTGIKANLPDRPKGKTVVIGAGKGAAQMARALESVWD
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHC
GPLDGLVVTRYGYGCDTRDIAIIEAAHPVPDAAGRAAASRLVETVSGLTEDDLVIALICG
CCCCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GGSALLPAPPVGLTLEDEIALNEMLLASGAPISAMNVVRKHLSTIKGGRLAAATRARVVS
CCCCCCCCCCCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LIVSDIPGDNPAHVASGPTVPDGSTRHDALEIVKQYGLQLPQAALDHLNSAKADAPRPDD
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCC
PVFLRHAHHIIASAGVSLEAAAALAKSQGIEPAILSDAIEGESRDVALVHAAIAREVLGR
CHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
NRPFPKPVVILSGGETTVTLRAKGAKGGKGGRNGEFALAMALAIDGQEGIHLLAADTDGI
CCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCC
DGSEDNAGAFADGGTVKRLRAAGLDPRRLLDGNDSYSGFAAVGDLFETGPTGTNVNDFRA
CCCCCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEE
ILIR
EEEC
>Mature Secondary Structure 
TISAPRDFLKSLFDAAVRAADPLTGIKANLPDRPKGKTVVIGAGKGAAQMARALESVWD
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHC
GPLDGLVVTRYGYGCDTRDIAIIEAAHPVPDAAGRAAASRLVETVSGLTEDDLVIALICG
CCCCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GGSALLPAPPVGLTLEDEIALNEMLLASGAPISAMNVVRKHLSTIKGGRLAAATRARVVS
CCCCCCCCCCCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LIVSDIPGDNPAHVASGPTVPDGSTRHDALEIVKQYGLQLPQAALDHLNSAKADAPRPDD
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCC
PVFLRHAHHIIASAGVSLEAAAALAKSQGIEPAILSDAIEGESRDVALVHAAIAREVLGR
CHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
NRPFPKPVVILSGGETTVTLRAKGAKGGKGGRNGEFALAMALAIDGQEGIHLLAADTDGI
CCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCC
DGSEDNAGAFADGGTVKRLRAAGLDPRRLLDGNDSYSGFAAVGDLFETGPTGTNVNDFRA
CCCCCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEE
ILIR
EEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]