Click here to switch to the map view.

The map label for this gene is lepB [H]

Identifier: 209548976

GI number: 209548976

Start: 1392384

End: 1393244

Strand: Reverse

Name: lepB [H]

Synonym: Rleg2_1373

Alternate gene names: 209548976

Gene position: 1393244-1392384 (Counterclockwise)

Preceding gene: 209548989

Following gene: 209548975

Centisome position: 30.7

GC content: 54.94

Gene sequence:

>861_bases
ATGGCCTATCTCGGGCGCGGCTGGAATGCCATCGCTTACTCTATCGGCGGCGTCTGCATCTTTATCGCGCAACTCTGGTT
GCTTGATGCTCCTTCGACCGCTGCTTTTGGGTATTTGCTGATCTCTGCCTGGCGTCTGATCGGCCTGTTGCATGGCTATC
GCACGGCAAGGAAGATGCCCGCGAACATCGTGTTTCCTTGGTACTCGCGGTGGTACAGTCTCGCTCTGATCTTTTCGATT
GTACCGCTCACCTTGGCGATGCTGGTTCGCAGTTTCCTCTTCCAGCCATTCACGATCCCGTCGAGTTCCATGTTGCCGAA
CTTGCGAAGCGGCGACTACATGTTCGCGCAAAAATACGTCTACGGGTACAGCCGCTATTCGTTCCCTTACGGATTTGGAC
CGGAGCATCGTATGTTTGGGCATGGACCGGACCGAGGAGACGTTGTCGTATTTCGGGGGTCGATGAATCCAGGGGGCGAT
TTCGTGAAACGCGTCGTCGGTCTGCCGGGTGACCGCATTCAAATGAAATCCGGTATTCTCTACTTGAATGGCAGCGCCGT
TGAGCGCGAACCGGCGGGTGATTTGACCTATCAGTCAGTAACTGTGCATGCATTTAAAGAGACGCTGCCATCCGGCCGCA
GCTATACGATCGTTGAGCAGGTGGACGACGCTCGTGGTGACAACACCAAGGAATTCATTGTCCCAGACGGGCATTATTTC
GTGCTGGGTGACAATCGTGACAACAGCCTGGATAGCCGCTTCGATATGGGGTTCGTCCCAGACGACAACATCTATGCGAA
GGCAGCGCTCCTGCTTTTCAATTCCGAGGATAAATCGCGGCAGGCGTCGTGGATCCAGTAG

Upstream 100 bases:

>100_bases
CAAACCTATTGAGTTTTTTATGAAAATTTTCAGAGCTTTTCGTGCTCGTCGCCCCATTTGCGCAGCCACGTTGGGATTTC
TATTCGGTCCGGATTTGGTT

Downstream 100 bases:

>100_bases
GCTTGAAGGGTACCCATCCTCTGGGAAGGCGGGTTCCCTCTGGACGAGGAGTCCTTGCCATCGGTGGTTGCTCTGAACGA
TGTACAGTGCCCCCTCTTCA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MAYLGRGWNAIAYSIGGVCIFIAQLWLLDAPSTAAFGYLLISAWRLIGLLHGYRTARKMPANIVFPWYSRWYSLALIFSI
VPLTLAMLVRSFLFQPFTIPSSSMLPNLRSGDYMFAQKYVYGYSRYSFPYGFGPEHRMFGHGPDRGDVVVFRGSMNPGGD
FVKRVVGLPGDRIQMKSGILYLNGSAVEREPAGDLTYQSVTVHAFKETLPSGRSYTIVEQVDDARGDNTKEFIVPDGHYF
VLGDNRDNSLDSRFDMGFVPDDNIYAKAALLLFNSEDKSRQASWIQ

Sequences:

>Translated_286_residues
MAYLGRGWNAIAYSIGGVCIFIAQLWLLDAPSTAAFGYLLISAWRLIGLLHGYRTARKMPANIVFPWYSRWYSLALIFSI
VPLTLAMLVRSFLFQPFTIPSSSMLPNLRSGDYMFAQKYVYGYSRYSFPYGFGPEHRMFGHGPDRGDVVVFRGSMNPGGD
FVKRVVGLPGDRIQMKSGILYLNGSAVEREPAGDLTYQSVTVHAFKETLPSGRSYTIVEQVDDARGDNTKEFIVPDGHYF
VLGDNRDNSLDSRFDMGFVPDDNIYAKAALLLFNSEDKSRQASWIQ
>Mature_285_residues
AYLGRGWNAIAYSIGGVCIFIAQLWLLDAPSTAAFGYLLISAWRLIGLLHGYRTARKMPANIVFPWYSRWYSLALIFSIV
PLTLAMLVRSFLFQPFTIPSSSMLPNLRSGDYMFAQKYVYGYSRYSFPYGFGPEHRMFGHGPDRGDVVVFRGSMNPGGDF
VKRVVGLPGDRIQMKSGILYLNGSAVEREPAGDLTYQSVTVHAFKETLPSGRSYTIVEQVDDARGDNTKEFIVPDGHYFV
LGDNRDNSLDSRFDMGFVPDDNIYAKAALLLFNSEDKSRQASWIQ

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=242, Percent_Identity=30.9917355371901, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 32146; Mature: 32015

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYLGRGWNAIAYSIGGVCIFIAQLWLLDAPSTAAFGYLLISAWRLIGLLHGYRTARKMP
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ANIVFPWYSRWYSLALIFSIVPLTLAMLVRSFLFQPFTIPSSSMLPNLRSGDYMFAQKYV
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHH
YGYSRYSFPYGFGPEHRMFGHGPDRGDVVVFRGSMNPGGDFVKRVVGLPGDRIQMKSGIL
HHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEECCEE
YLNGSAVEREPAGDLTYQSVTVHAFKETLPSGRSYTIVEQVDDARGDNTKEFIVPDGHYF
EEECCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCEEEECCCEEE
VLGDNRDNSLDSRFDMGFVPDDNIYAKAALLLFNSEDKSRQASWIQ
EEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
AYLGRGWNAIAYSIGGVCIFIAQLWLLDAPSTAAFGYLLISAWRLIGLLHGYRTARKMP
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ANIVFPWYSRWYSLALIFSIVPLTLAMLVRSFLFQPFTIPSSSMLPNLRSGDYMFAQKYV
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHH
YGYSRYSFPYGFGPEHRMFGHGPDRGDVVVFRGSMNPGGDFVKRVVGLPGDRIQMKSGIL
HHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEECCEE
YLNGSAVEREPAGDLTYQSVTVHAFKETLPSGRSYTIVEQVDDARGDNTKEFIVPDGHYF
EEECCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCEEEECCCEEE
VLGDNRDNSLDSRFDMGFVPDDNIYAKAALLLFNSEDKSRQASWIQ
EEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA