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The map label for this gene is mauR [H]

Identifier: 209548055

GI number: 209548055

Start: 459352

End: 460203

Strand: Direct

Name: mauR [H]

Synonym: Rleg2_0448

Alternate gene names: 209548055

Gene position: 459352-460203 (Clockwise)

Preceding gene: 209548053

Following gene: 209548057

Centisome position: 10.12

GC content: 63.26

Gene sequence:

>852_bases
ATGGAATGGAGCGACCTGAAGATTTTTCTGGCGATCGCGCGGTTCGGAACGCTGGGTGCAGCAGCCCGCAGCCTCCGTCT
GACGCAGCCGACGATGGGCCGTCGGTTGCGTTCCCTGGAAGCGTCTGTTGGGCAGACGTTATTTCAGCGCACGACTGAGG
GCTTCGTGCTGACCGAGGAAGGCGCGGCCGTTCTTGCCGGTGCCGAACGCATCGAGGAGGAGACGCTTGCTATGGAGCGC
ATCCTTGCCGGTGGCAGCCGCCAGCTCGGTGGTTTTCTCAGGCTGTCCTCGTCCGACTGGTTCGGCGCGCATGTGCTTTC
GCCGGTGCTGGCGGAGTTCTCGCAACTCCATCCCAAGGTGGTGGTCGAACTATTGACTGACAGCCGGCTCCTCAGCCTGC
CGCGACGAGAAGCCGACCTCGTTTTTCGTATTCAGCCCTTTACTGAAGCGGAGATCATATCCCGCAAGCTTATCCATATT
AAATACGGCCTTTACATCCGTCGCGGCGCGCCGCACCCGAGGGCATTTGACGGGGTGGGCGCCCGCCTCGTCACCATGGA
CCAAGCTTTCGGCGACATGCCGGATGCTGGCTGGCTGCAGCGCCTCTTGCCGCGGGCCGAAATTGCCATGCGCAGCAACA
GCCGCGATGTTCAGGCGACGCTTTGTGCCAATGGAGCGGGGCTGGCCGTCCTGCCCCGGCCGCTCGGCGATTCCCTTGCT
GCTATTGAATTGGTGGATCTTGGCGAGGCGCCGCCCGGCCGCGACACCTGGGTCGGCTATCACCGCGACATGAAACGCCT
GGCGCGGCTGCGCGCCCTGCTGGATCTCGTCATCGAGAGATTGACGCACTGA

Upstream 100 bases:

>100_bases
GCAACGGGCTTTTCCGGAAGAAAGATCGCTCATTGAAACGCGAATGAAAATAGAAGAAAAGGACTGAAGGCCATGCATTT
TTGTTTGATGGATGCGAGCG

Downstream 100 bases:

>100_bases
ACCGGCGGGGAGTATGATCTGAAATATGTGAGGGGCCTTTTGAGGCGACATCGCGTCATTTAGTTAGGTGTGCAGTCATC
GCTCCCAGTAGGGGACAGGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MEWSDLKIFLAIARFGTLGAAARSLRLTQPTMGRRLRSLEASVGQTLFQRTTEGFVLTEEGAAVLAGAERIEEETLAMER
ILAGGSRQLGGFLRLSSSDWFGAHVLSPVLAEFSQLHPKVVVELLTDSRLLSLPRREADLVFRIQPFTEAEIISRKLIHI
KYGLYIRRGAPHPRAFDGVGARLVTMDQAFGDMPDAGWLQRLLPRAEIAMRSNSRDVQATLCANGAGLAVLPRPLGDSLA
AIELVDLGEAPPGRDTWVGYHRDMKRLARLRALLDLVIERLTH

Sequences:

>Translated_283_residues
MEWSDLKIFLAIARFGTLGAAARSLRLTQPTMGRRLRSLEASVGQTLFQRTTEGFVLTEEGAAVLAGAERIEEETLAMER
ILAGGSRQLGGFLRLSSSDWFGAHVLSPVLAEFSQLHPKVVVELLTDSRLLSLPRREADLVFRIQPFTEAEIISRKLIHI
KYGLYIRRGAPHPRAFDGVGARLVTMDQAFGDMPDAGWLQRLLPRAEIAMRSNSRDVQATLCANGAGLAVLPRPLGDSLA
AIELVDLGEAPPGRDTWVGYHRDMKRLARLRALLDLVIERLTH
>Mature_283_residues
MEWSDLKIFLAIARFGTLGAAARSLRLTQPTMGRRLRSLEASVGQTLFQRTTEGFVLTEEGAAVLAGAERIEEETLAMER
ILAGGSRQLGGFLRLSSSDWFGAHVLSPVLAEFSQLHPKVVVELLTDSRLLSLPRREADLVFRIQPFTEAEIISRKLIHI
KYGLYIRRGAPHPRAFDGVGARLVTMDQAFGDMPDAGWLQRLLPRAEIAMRSNSRDVQATLCANGAGLAVLPRPLGDSLA
AIELVDLGEAPPGRDTWVGYHRDMKRLARLRALLDLVIERLTH

Specific function: Transcriptional activator of the mau genes involved in methylamine metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=25.6849315068493, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787601, Length=186, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=176, Percent_Identity=28.4090909090909, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87081978, Length=154, Percent_Identity=29.8701298701299, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31283; Mature: 31283

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWSDLKIFLAIARFGTLGAAARSLRLTQPTMGRRLRSLEASVGQTLFQRTTEGFVLTEE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
GAAVLAGAERIEEETLAMERILAGGSRQLGGFLRLSSSDWFGAHVLSPVLAEFSQLHPKV
CCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCHHH
VVELLTDSRLLSLPRREADLVFRIQPFTEAEIISRKLIHIKYGLYIRRGAPHPRAFDGVG
HHHHHHCCHHHHCCCCCCCEEEEECCCCHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCC
ARLVTMDQAFGDMPDAGWLQRLLPRAEIAMRSNSRDVQATLCANGAGLAVLPRPLGDSLA
CEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCHH
AIELVDLGEAPPGRDTWVGYHRDMKRLARLRALLDLVIERLTH
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWSDLKIFLAIARFGTLGAAARSLRLTQPTMGRRLRSLEASVGQTLFQRTTEGFVLTEE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
GAAVLAGAERIEEETLAMERILAGGSRQLGGFLRLSSSDWFGAHVLSPVLAEFSQLHPKV
CCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCHHH
VVELLTDSRLLSLPRREADLVFRIQPFTEAEIISRKLIHIKYGLYIRRGAPHPRAFDGVG
HHHHHHCCHHHHCCCCCCCEEEEECCCCHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCC
ARLVTMDQAFGDMPDAGWLQRLLPRAEIAMRSNSRDVQATLCANGAGLAVLPRPLGDSLA
CEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCHH
AIELVDLGEAPPGRDTWVGYHRDMKRLARLRALLDLVIERLTH
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957249 [H]