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The map label for this gene is pgl [H]

Identifier: 209547970

GI number: 209547970

Start: 367218

End: 367916

Strand: Reverse

Name: pgl [H]

Synonym: Rleg2_0362

Alternate gene names: 209547970

Gene position: 367916-367218 (Counterclockwise)

Preceding gene: 209547971

Following gene: 209547969

Centisome position: 8.11

GC content: 63.81

Gene sequence:

>699_bases
ATGGCATCGACCCTGCATTCCTTCGCCAGCCCCGCAGATCTCGCCGGCAGCCTTGCCGAGAAGGTTGCCGATACGCTTTC
GGCGGCGATCTCAGCCCGCGGAACAGCGTCCATCGCCGTTTCCGGCGGCTCGACCCCGAAGGCCTTCTTCCAGGTGCTGT
CGACGCGCGATATCGCCTGGGACAAGGTGACGATCACGCTTGTCGACGAACGTTTCGTGCCGGCCGACAATGCGCGCTCG
AACCACATGCTGGTCGATGCCAATCTCTTGCAGAACAAGGCGAAGTCGGCGCGTTTCGTGCCGCTTTACCAGCCGGCCGC
CTCCGTCGAGGAAGCCGCACGGCTTGCGACTGAAAAGAGCGCCGAAATCGGCATTCCCTTCGATGTCGTCATCCTCGGCA
TGGGCGGCGACGGCCACACCGCCTCGTTCTTTCCCGGCGGCAGCAATCTTGCCACGGCGCTCGATGCATCGACACCGCGC
GGCGTCATCACCATGGAAGCGGAGGGGGCCGGCGAGCCGCGCCTGACCTTTACCTTCTCCAGTCTTCAGGATGCCGCACT
CCTGGTTCTCCATATTGAGGGCGAAGGCAAAAAAGACGTTCTCGCCAAGGCGGAAGGCAGCGGTGACGAGGCAGACATGC
CGATCCGCGCCATTCTGCGCCGGGCCACTTCCCCGGTCGAGATCTACTGGGCTCCCTGA

Upstream 100 bases:

>100_bases
GTGCAGGGCTATACCGCCGGCACCTGGGGCCCGAGCCAGGCCATTGCGCTGATCGAGCGCGACGGCCGCACCTGGCATGA
CGATATCTAGGACGAAACCG

Downstream 100 bases:

>100_bases
TCGACCGTCAATCCGGATTGAATATCAGGCCAGAGCCGCCGAAACAGATTAGACAACGAACAAGGCAGGGATCTTCCATG
TCCGCTCACGCACGCATTTC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MASTLHSFASPADLAGSLAEKVADTLSAAISARGTASIAVSGGSTPKAFFQVLSTRDIAWDKVTITLVDERFVPADNARS
NHMLVDANLLQNKAKSARFVPLYQPAASVEEAARLATEKSAEIGIPFDVVILGMGGDGHTASFFPGGSNLATALDASTPR
GVITMEAEGAGEPRLTFTFSSLQDAALLVLHIEGEGKKDVLAKAEGSGDEADMPIRAILRRATSPVEIYWAP

Sequences:

>Translated_232_residues
MASTLHSFASPADLAGSLAEKVADTLSAAISARGTASIAVSGGSTPKAFFQVLSTRDIAWDKVTITLVDERFVPADNARS
NHMLVDANLLQNKAKSARFVPLYQPAASVEEAARLATEKSAEIGIPFDVVILGMGGDGHTASFFPGGSNLATALDASTPR
GVITMEAEGAGEPRLTFTFSSLQDAALLVLHIEGEGKKDVLAKAEGSGDEADMPIRAILRRATSPVEIYWAP
>Mature_231_residues
ASTLHSFASPADLAGSLAEKVADTLSAAISARGTASIAVSGGSTPKAFFQVLSTRDIAWDKVTITLVDERFVPADNARSN
HMLVDANLLQNKAKSARFVPLYQPAASVEEAARLATEKSAEIGIPFDVVILGMGGDGHTASFFPGGSNLATALDASTPRG
VITMEAEGAGEPRLTFTFSSLQDAALLVLHIEGEGKKDVLAKAEGSGDEADMPIRAILRRATSPVEIYWAP

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=223, Percent_Identity=30.0448430493274, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI6912586, Length=221, Percent_Identity=29.8642533936652, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533060, Length=216, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533058, Length=216, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321957, Length=210, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321687, Length=216, Percent_Identity=25, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24227; Mature: 24095

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTLHSFASPADLAGSLAEKVADTLSAAISARGTASIAVSGGSTPKAFFQVLSTRDIAW
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCC
DKVTITLVDERFVPADNARSNHMLVDANLLQNKAKSARFVPLYQPAASVEEAARLATEKS
CEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCC
AEIGIPFDVVILGMGGDGHTASFFPGGSNLATALDASTPRGVITMEAEGAGEPRLTFTFS
CCCCCCEEEEEEEECCCCCEEEECCCCCCCEEEECCCCCCCEEEEECCCCCCCEEEEEEC
SLQDAALLVLHIEGEGKKDVLAKAEGSGDEADMPIRAILRRATSPVEIYWAP
CCCCEEEEEEEECCCCCHHEEEECCCCCCCCCCCHHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
ASTLHSFASPADLAGSLAEKVADTLSAAISARGTASIAVSGGSTPKAFFQVLSTRDIAW
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCC
DKVTITLVDERFVPADNARSNHMLVDANLLQNKAKSARFVPLYQPAASVEEAARLATEKS
CEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCC
AEIGIPFDVVILGMGGDGHTASFFPGGSNLATALDASTPRGVITMEAEGAGEPRLTFTFS
CCCCCCEEEEEEEECCCCCEEEECCCCCCCEEEECCCCCCCEEEEECCCCCCCEEEEEEC
SLQDAALLVLHIEGEGKKDVLAKAEGSGDEADMPIRAILRRATSPVEIYWAP
CCCCEEEEEEEECCCCCHHEEEECCCCCCCCCCCHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]