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The map label for this gene is yjjN [H]

Identifier: 209547759

GI number: 209547759

Start: 143745

End: 144761

Strand: Reverse

Name: yjjN [H]

Synonym: Rleg2_0148

Alternate gene names: 209547759

Gene position: 144761-143745 (Counterclockwise)

Preceding gene: 209547760

Following gene: 209547756

Centisome position: 3.19

GC content: 65.19

Gene sequence:

>1017_bases
ATGAAAGCAGTCGTTTGCCGGGAGCCCGGCGTGCTCGAGATCGCCGAACGCCCTTCGCCTGCCGCACCGGCACCCGGCTG
GGTGCGGTTGGCCGTCAGCCATGTCGGCATCTGCGGCACCGACTATCACATCTTCGAGGGCAAACACCCTTTCCTCGAAT
ATCCCCGGGTGATGGGGCATGAGGTCTCGGCGACGGTGCTGGAAGCCGGCGACGGTGTCGCCATGGCGGTGGGAACACCC
GTCATCGTCAATCCCTATCTCTCCTGCGGCCAATGCGTCGCCTGCATCAAGGGCAAGCCGAATTGCTGCACCAATATCAA
GGTGCTCGGCGTCCATACGGACGGCGCCTTCTGCCAGGAGATCTCGGTTCCCGCAGGCAACCTCTATGCCGCCGAGGGCT
TGAGCCTCGAGGCGGCGGCAACCGTCGAGTTCCTGGCGATCGGCGCCCATGCCGTGCGCCGCTCGATGACCGGCGCCGGT
GCCAAGGCGCTCGTCATCGGCGCCGGCCCGATCGGGCTCGGGGCGGCGATCTTCTCGCGCATTGCAGGCCATGACGTGAC
GCTGCTCGATACCAGTGCCGAGCGGCTGCAGATGGCCTCGGACCGTTTCGGCTTCACCTCCGGCATCGTCGCCAACGAGC
AAACGGCGGACGCCCTGCGGGAAAAAACCGATGGCGACGGTTTCGACGTGGTCTTCGATGCCACGGGTTACGGCCCGTCG
ATGGAAAAAGCCTTCTCCTTCGTCGCCCATGGCGGAGCACTGGTGCTGGTCAGCGTCGTCAAGGACGACATCCGCTTCTC
CGACCCCGAATTCCACAAACGCGAAATGACGCTGATCGGCAGCCGCAACGCCACCCGCGCCGATTTCGAGCACGTGGCGG
CTTCGATCGCCAAGGGGCTGGTGCCGGTGGACAAGCTCATCACCCATCGCACGACGCTTGCCGATGCGCCGCGTGATCTC
GCCCGCTGGGCGCATGAGAAGAGCGGGCTGATCAAGGCGGTGATCAGGGTTGGTTAG

Upstream 100 bases:

>100_bases
GTCGTGCAGGGCACGTCCCCTCGCCCCGTTTACGGGGAGAGGGTTAGGGTGAGGGGCAAATCTCGCGACATAGAGTAAAA
ACGAAGAATCGAGATCCGTC

Downstream 100 bases:

>100_bases
GGAGGGTTAGCGCCCCGTTTCGCCGAGCTGGATCGGCGGGACAAGCCCCTCATCCGCCTGCCGGCACCTTCTCCCCGCTT
GCGGGGCGAAGGGGGCGAGC

Product: alcohol dehydrogenase GroES domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKAVVCREPGVLEIAERPSPAAPAPGWVRLAVSHVGICGTDYHIFEGKHPFLEYPRVMGHEVSATVLEAGDGVAMAVGTP
VIVNPYLSCGQCVACIKGKPNCCTNIKVLGVHTDGAFCQEISVPAGNLYAAEGLSLEAAATVEFLAIGAHAVRRSMTGAG
AKALVIGAGPIGLGAAIFSRIAGHDVTLLDTSAERLQMASDRFGFTSGIVANEQTADALREKTDGDGFDVVFDATGYGPS
MEKAFSFVAHGGALVLVSVVKDDIRFSDPEFHKREMTLIGSRNATRADFEHVAASIAKGLVPVDKLITHRTTLADAPRDL
ARWAHEKSGLIKAVIRVG

Sequences:

>Translated_338_residues
MKAVVCREPGVLEIAERPSPAAPAPGWVRLAVSHVGICGTDYHIFEGKHPFLEYPRVMGHEVSATVLEAGDGVAMAVGTP
VIVNPYLSCGQCVACIKGKPNCCTNIKVLGVHTDGAFCQEISVPAGNLYAAEGLSLEAAATVEFLAIGAHAVRRSMTGAG
AKALVIGAGPIGLGAAIFSRIAGHDVTLLDTSAERLQMASDRFGFTSGIVANEQTADALREKTDGDGFDVVFDATGYGPS
MEKAFSFVAHGGALVLVSVVKDDIRFSDPEFHKREMTLIGSRNATRADFEHVAASIAKGLVPVDKLITHRTTLADAPRDL
ARWAHEKSGLIKAVIRVG
>Mature_338_residues
MKAVVCREPGVLEIAERPSPAAPAPGWVRLAVSHVGICGTDYHIFEGKHPFLEYPRVMGHEVSATVLEAGDGVAMAVGTP
VIVNPYLSCGQCVACIKGKPNCCTNIKVLGVHTDGAFCQEISVPAGNLYAAEGLSLEAAATVEFLAIGAHAVRRSMTGAG
AKALVIGAGPIGLGAAIFSRIAGHDVTLLDTSAERLQMASDRFGFTSGIVANEQTADALREKTDGDGFDVVFDATGYGPS
MEKAFSFVAHGGALVLVSVVKDDIRFSDPEFHKREMTLIGSRNATRADFEHVAASIAKGLVPVDKLITHRTTLADAPRDL
ARWAHEKSGLIKAVIRVG

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=334, Percent_Identity=29.0419161676647, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4501939, Length=349, Percent_Identity=24.3553008595989, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI156523966, Length=349, Percent_Identity=24.3553008595989, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI226510992, Length=336, Percent_Identity=40.1785714285714, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1787863, Length=316, Percent_Identity=34.1772151898734, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1788407, Length=344, Percent_Identity=29.3604651162791, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788073, Length=341, Percent_Identity=27.8592375366569, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790045, Length=293, Percent_Identity=26.2798634812287, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1790718, Length=310, Percent_Identity=26.1290322580645, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786825, Length=369, Percent_Identity=22.4932249322493, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788075, Length=326, Percent_Identity=24.8466257668712, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082125, Length=330, Percent_Identity=25.1515151515152, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=290, Percent_Identity=31.0344827586207, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17562878, Length=242, Percent_Identity=30.5785123966942, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322619, Length=331, Percent_Identity=32.02416918429, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6319955, Length=331, Percent_Identity=32.02416918429, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319257, Length=358, Percent_Identity=30.7262569832402, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323099, Length=356, Percent_Identity=27.247191011236, Blast_Score=112, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6319258, Length=334, Percent_Identity=26.6467065868263, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320033, Length=339, Percent_Identity=25.3687315634218, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17137530, Length=336, Percent_Identity=27.9761904761905, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17737897, Length=336, Percent_Identity=27.3809523809524, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17737895, Length=349, Percent_Identity=26.0744985673352, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35499; Mature: 35499

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVCREPGVLEIAERPSPAAPAPGWVRLAVSHVGICGTDYHIFEGKHPFLEYPRVMGH
CCEEEECCCCEEEEECCCCCCCCCCHHEEEEEHHCEECCCCEEEECCCCCHHHCHHHHCC
EVSATVLEAGDGVAMAVGTPVIVNPYLSCGQCVACIKGKPNCCTNIKVLGVHTDGAFCQE
CCEEEEEECCCCEEEEECCCEEECCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCHHHC
ISVPAGNLYAAEGLSLEAAATVEFLAIGAHAVRRSMTGAGAKALVIGAGPIGLGAAIFSR
CCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHH
IAGHDVTLLDTSAERLQMASDRFGFTSGIVANEQTADALREKTDGDGFDVVFDATGYGPS
HCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCC
MEKAFSFVAHGGALVLVSVVKDDIRFSDPEFHKREMTLIGSRNATRADFEHVAASIAKGL
HHHHHHHHHCCCCEEEHEEHHHHCCCCCCCHHCEEEEEEECCCCCHHHHHHHHHHHHHCC
VPVDKLITHRTTLADAPRDLARWAHEKSGLIKAVIRVG
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHEECC
>Mature Secondary Structure
MKAVVCREPGVLEIAERPSPAAPAPGWVRLAVSHVGICGTDYHIFEGKHPFLEYPRVMGH
CCEEEECCCCEEEEECCCCCCCCCCHHEEEEEHHCEECCCCEEEECCCCCHHHCHHHHCC
EVSATVLEAGDGVAMAVGTPVIVNPYLSCGQCVACIKGKPNCCTNIKVLGVHTDGAFCQE
CCEEEEEECCCCEEEEECCCEEECCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCHHHC
ISVPAGNLYAAEGLSLEAAATVEFLAIGAHAVRRSMTGAGAKALVIGAGPIGLGAAIFSR
CCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHH
IAGHDVTLLDTSAERLQMASDRFGFTSGIVANEQTADALREKTDGDGFDVVFDATGYGPS
HCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCC
MEKAFSFVAHGGALVLVSVVKDDIRFSDPEFHKREMTLIGSRNATRADFEHVAASIAKGL
HHHHHHHHHCCCCEEEHEEHHHHCCCCCCCHHCEEEEEEECCCCCHHHHHHHHHHHHHCC
VPVDKLITHRTTLADAPRDLARWAHEKSGLIKAVIRVG
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]