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The map label for this gene is safA [H]

Identifier: 209400612

GI number: 209400612

Start: 2019608

End: 2019790

Strand: Reverse

Name: safA [H]

Synonym: ECH74115_2113

Alternate gene names: 209400612

Gene position: 2019790-2019608 (Counterclockwise)

Preceding gene: 209400692

Following gene: 209396156

Centisome position: 36.25

GC content: 36.07

Gene sequence:

>183_bases
GTGAAAAACAAAATCACGCAAAGAGACAACTATAAAGAAATCATGTCTGTAATTGTGGTTATCTTATTACTGACCCTTAC
GTTGATAGCCATTTTTTCGGCAATTGATCAGCTGGGTATTTCAGAAATGGGTCGCATTGCAAGAGATCTTACACATTTCA
TTGTCAATAGTTTGCAAGACTGA

Upstream 100 bases:

>100_bases
CCTATTTCCTCTTTTCTCAAGCCTGTTATATTAAGCATACTGATTAACGATTTTTAACGTTATCCGCTAAATAAACATAT
TTGAAATGCATGCGACCACA

Downstream 100 bases:

>100_bases
AAATAAACAGCAAATTATAAATATGAAATGTTAAAAAAGTATCGATAAAACTTTATTGTTTTAAGGAGATAAAATGTCGC
TCGTTTGTTCTGTTATATTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 60; Mature: 60

Protein sequence:

>60_residues
MKNKITQRDNYKEIMSVIVVILLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIVNSLQD

Sequences:

>Translated_60_residues
MKNKITQRDNYKEIMSVIVVILLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIVNSLQD
>Mature_60_residues
MKNKITQRDNYKEIMSVIVVILLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIVNSLQD

Specific function: Connects the signal transduction between the two- component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SafA family [H]

Homologues:

Organism=Escherichia coli, GI1787777, Length=58, Percent_Identity=93.1034482758621, Blast_Score=84, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 6818; Mature: 6818

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKITQRDNYKEIMSVIVVILLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIVNSLQD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNKITQRDNYKEIMSVIVVILLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIVNSLQD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]