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The map label for this gene is ydeP

Identifier: 209400692

GI number: 209400692

Start: 2020053

End: 2022332

Strand: Reverse

Name: ydeP

Synonym: ECH74115_2114

Alternate gene names: 209400692

Gene position: 2022332-2020053 (Counterclockwise)

Preceding gene: 209396169

Following gene: 209400612

Centisome position: 36.29

GC content: 50.04

Gene sequence:

>2280_bases
ATGAAGAAAAAAATTGAATCCTACCAGGGTGCTGCCGGTGGTTGGGGTGCTGTTAAATCCGTAGCGAATGCAGTACGTAA
GCAGATGGATATACGCCAGGATGTTATTGCCATGTTTGACATGAATAAGCCAGAGGGCTTTGACTGTCCGGGTTGTGCAT
GGCCAGATCCTAAGCACAGTGCGTCATTCGACATTTGTGAAAACGGCGCAAAAGCAATCGCCTGGGAAGTCACGGATAAG
CAGGTAAATGCCTCTTTCTTTGCTCAGAATACGGTTCAATCATTACTTACCTGGGGAGATCACGAGCTTGAGGCTGCGGG
ACGTCTCACTCAGCCTTTGAAATATGATGCTGTCAGCGACTGTTACAAGCCATTAAGCTGGCAACAAGCTTTCGACGAAA
TTGGCGCACGCCTTCAAAGCTATAGTGATCCCAATCAGGTTGAATTCTATACTTCGGGCCGCACTTCCAATGAAGCTGCC
TTTCTTTATCAGCTTTTTGCCCGTGAATACGGGAGCAATAACTTTCCCGACTGCTCCAACATGTGCCATGAACCGACAAG
CGTGGGTTTGGCAGCGAGTATCGGTGTAGGTAAAGGGACCGTGTTGCTGGAAGACTTTGAGAAGTGCGATTTAGTCATTT
GCATTGGGCATAACCCTGGTACAAACCACCCTCGCATGCTGACTTCGTTGCGCGCTTTAGTGAAACGGGGAGCGAAAATG
ATCGCCATCAATCCTCTACAGGAACGTGGCCTGGAGCGATTTACCGCACCGCAAAACCCGTTTGAAATGCTGACGAACTC
TGAGACTCAGTTGGCCAGTGCCTACTATAACGTGCGCATTGGTGGTGATATGGCGTTGCTCAAGGGGATGATGCGCCTGT
TAATTGAGCGCGATGATGCTGCAAGCGCCGCAGGTCGGCCCTCATTGCTGGATGACGAATTTATTCAAACGCATACCGTC
GGCTTTGACGAGCTACGCCGTGACGTGCTCAATTCCGAGTGGAAAGATATCGAACGTATTTCTGGACTAAGTCAGACACA
AATCGCCGAACTGGCTGATGCATATGCCGCTGCCGAACGAACCATTATCTGTTACGGAATGGGGATCACTCAGCACGAAC
ATGGTACCCAGAATGTACAGCAACTGGTCAATCTGCTGTTGATGAAAGGTAACATTGGCAAGCCTGGTGCGGGTATCTGC
CCACTACGTGGCCACTCTAATGTACAGGGCGACCGAACCGTCGGTATCACCGAGAAACCGTCTGTAGAGTTTCTGGCTCG
CCTGGGTGAGCGCTATGGCTTCACCCCACCTCATGTACCTGGACATGCTGCAATTGCCAGCATGCAAGCAATATGTACGG
GGCAGGCTCGAGCATTGATCTGCATGGGGGGCAACTTTGCACTGGCAATGCCAGATCGGGAAGCGAGCGCTGTACCGTTA
ACGCAATTAGATTTGGCGGTACACGTAGCCACTAAGCTTAACCGCTCTCATCTGCTGACCGCACGGCATAGCTATATTCT
GCCGGTTCTGGGACGTAGCGAGATTGACATGCAAAAAAGCGGTGCGCAGGCGGTAACCGTTGAGGATTCAATGTCGATGA
TTCATGCCTCGCGTGGCGTGTTAAAACCCGCCGGTGTAATGCTGAAATCAGAGTGTGCTGTGGTCGCGGGAATCGCGCAG
GCAACACTACCCCAGAGCGTGGTAGCCTGGGAGTATCTGGTGGAAGATTATGATCGCATTCGCAATGACATTGAAGCTGT
GCTGCCAGAGTTCGCCGACTATAACCAACGCATCCGTCATCCCGGTGGTTTTCACCTGATAAATGCAGCTGCTGAAAGGC
GCTGGATGACGCCGTCAGGTAAGGCTAATTTCATTACCAGCAAAGGGCTGTTAGAAGATCCCTCTTCAGCGTTTAACAGT
AAGCTGGTCATGGCGACAGTACGCAGCCACGATCAGTACAACACGACGATTTATGGTATGGATGATCGCTATCGAGGGGT
ATTCGGTCAACGAGATGTGGTCTTTATGAGTGCTAAACAAGCTAAAATTTGCCGTGTAAAAAACGGCGAAAGAGTTAATC
TTATTGCGCTTACGCCAGACGGTAAGCGCAGCTCACGCCGCATGGATAGATTAAAAGTGGTCATTTACCCTATGGCTGAC
CGCTCACTGGTGACCTATTTTCCAGAATCGAATCACATGCTAACACTTGATAACCACGATCCATTAAGTGGCATTCCTGG
CTATAAAAGTATTCCGGTTGAATTAGAACCATCAAATTAA

Upstream 100 bases:

>100_bases
CCTACTCTTATATATCCATGTTGGCGATAATCCCTTTGTATGTACTGTGCATCATCGCTATTACAAATCCTAATAATTCA
TTTCCACACAGGATAAGTAG

Downstream 100 bases:

>100_bases
TGCCTCTTCTCATTTCTTCTGCTGTCATCCGCACAGCAGAAGAATTCCTCATTGATTATTATCGCGCAATTTGCTCACAT
GGATTAAATTAAACTACATA

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 759; Mature: 759

Protein sequence:

>759_residues
MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKPEGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDK
QVNASFFAQNTVQSLLTWGDHELEAAGRLTQPLKYDAVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAA
FLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHNPGTNHPRMLTSLRALVKRGAKM
IAINPLQERGLERFTAPQNPFEMLTNSETQLASAYYNVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTV
GFDELRRDVLNSEWKDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNIGKPGAGIC
PLRGHSNVQGDRTVGITEKPSVEFLARLGERYGFTPPHVPGHAAIASMQAICTGQARALICMGGNFALAMPDREASAVPL
TQLDLAVHVATKLNRSHLLTARHSYILPVLGRSEIDMQKSGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAGIAQ
ATLPQSVVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANFITSKGLLEDPSSAFNS
KLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAKICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMAD
RSLVTYFPESNHMLTLDNHDPLSGIPGYKSIPVELEPSN

Sequences:

>Translated_759_residues
MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKPEGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDK
QVNASFFAQNTVQSLLTWGDHELEAAGRLTQPLKYDAVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAA
FLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHNPGTNHPRMLTSLRALVKRGAKM
IAINPLQERGLERFTAPQNPFEMLTNSETQLASAYYNVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTV
GFDELRRDVLNSEWKDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNIGKPGAGIC
PLRGHSNVQGDRTVGITEKPSVEFLARLGERYGFTPPHVPGHAAIASMQAICTGQARALICMGGNFALAMPDREASAVPL
TQLDLAVHVATKLNRSHLLTARHSYILPVLGRSEIDMQKSGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAGIAQ
ATLPQSVVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANFITSKGLLEDPSSAFNS
KLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAKICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMAD
RSLVTYFPESNHMLTLDNHDPLSGIPGYKSIPVELEPSN
>Mature_759_residues
MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKPEGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDK
QVNASFFAQNTVQSLLTWGDHELEAAGRLTQPLKYDAVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAA
FLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHNPGTNHPRMLTSLRALVKRGAKM
IAINPLQERGLERFTAPQNPFEMLTNSETQLASAYYNVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTV
GFDELRRDVLNSEWKDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNIGKPGAGIC
PLRGHSNVQGDRTVGITEKPSVEFLARLGERYGFTPPHVPGHAAIASMQAICTGQARALICMGGNFALAMPDREASAVPL
TQLDLAVHVATKLNRSHLLTARHSYILPVLGRSEIDMQKSGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAGIAQ
ATLPQSVVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANFITSKGLLEDPSSAFNS
KLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAKICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMAD
RSLVTYFPESNHMLTLDNHDPLSGIPGYKSIPVELEPSN

Specific function: Probably involved in acid resistance

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787778, Length=759, Percent_Identity=99.3412384716733, Blast_Score=1582, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=308, Percent_Identity=30.8441558441558, Blast_Score=156, Evalue=6e-39,
Organism=Escherichia coli, GI3868720, Length=376, Percent_Identity=25.7978723404255, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI3868719, Length=376, Percent_Identity=25.7978723404255, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YDEP_ECO57 (Q8XAX1)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B90892
- PIR:   G85725
- RefSeq:   NP_287654.1
- RefSeq:   NP_310133.1
- ProteinModelPortal:   Q8XAX1
- SMR:   Q8XAX1
- EnsemblBacteria:   EBESCT00000026683
- EnsemblBacteria:   EBESCT00000059703
- GeneID:   917305
- GeneID:   960666
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2207
- KEGG:   ecs:ECs2106
- GeneTree:   EBGT00050000009000
- HOGENOM:   HBG638124
- OMA:   FDEIGER
- ProtClustDB:   PRK09939
- BioCyc:   ECOL83334:ECS2106-MONOMER
- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR010046
- Gene3D:   G3DSA:2.40.40.20
- TIGRFAMs:   TIGR01701

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding; SSF50692 Asp_decarb_fold

EC number: NA

Molecular weight: Translated: 83554; Mature: 83554

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKPEGFDCPGCAWPDPKHS
CCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
ASFDICENGAKAIAWEVTDKQVNASFFAQNTVQSLLTWGDHELEAAGRLTQPLKYDAVSD
CCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHH
CYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAAFLYQLFAREYGSNNFPDCSN
HHCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHH
MCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHNPGTNHPRMLTSLRALVKRGAKM
HCCCCCCCCEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEE
IAINPLQERGLERFTAPQNPFEMLTNSETQLASAYYNVRIGGDMALLKGMMRLLIERDDA
EEECCHHHCCHHHHCCCCCHHHHHCCCCHHHEEEEEEEEECCCHHHHHHHHHHHHCCCCC
ASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEWKDIERISGLSQTQIAELADAYAAAER
CCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCC
TIICYGMGITQHEHGTQNVQQLVNLLLMKGNIGKPGAGICPLRGHSNVQGDRTVGITEKP
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
SVEFLARLGERYGFTPPHVPGHAAIASMQAICTGQARALICMGGNFALAMPDREASAVPL
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCCCCH
TQLDLAVHVATKLNRSHLLTARHSYILPVLGRSEIDMQKSGAQAVTVEDSMSMIHASRGV
HHHHHHHHHHHHCCHHHEEEECCCEEEEECCCCCCCHHHCCCCEEEEHHHHHHHHHHCCC
LKPAGVMLKSECAVVAGIAQATLPQSVVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRH
CCCCCCEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
PGGFHLINAAAERRWMTPSGKANFITSKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGM
CCCEEEEEHHHHCCCCCCCCCCCEEECCCCCCCCHHHHCCEEEEEEECCCCCCCCEEEEC
DDRYRGVFGQRDVVFMSAKQAKICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMAD
CCHHCCCCCCCCEEEEECCCCEEEEECCCCEEEEEEECCCCCHHHHHHCEEEEEEEECCC
RSLVTYFPESNHMLTLDNHDPLSGIPGYKSIPVELEPSN
CCEEEECCCCCCEEEECCCCCCCCCCCCCCCCEEECCCC
>Mature Secondary Structure
MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKPEGFDCPGCAWPDPKHS
CCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
ASFDICENGAKAIAWEVTDKQVNASFFAQNTVQSLLTWGDHELEAAGRLTQPLKYDAVSD
CCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHH
CYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAAFLYQLFAREYGSNNFPDCSN
HHCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHH
MCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHNPGTNHPRMLTSLRALVKRGAKM
HCCCCCCCCEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEE
IAINPLQERGLERFTAPQNPFEMLTNSETQLASAYYNVRIGGDMALLKGMMRLLIERDDA
EEECCHHHCCHHHHCCCCCHHHHHCCCCHHHEEEEEEEEECCCHHHHHHHHHHHHCCCCC
ASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEWKDIERISGLSQTQIAELADAYAAAER
CCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCC
TIICYGMGITQHEHGTQNVQQLVNLLLMKGNIGKPGAGICPLRGHSNVQGDRTVGITEKP
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
SVEFLARLGERYGFTPPHVPGHAAIASMQAICTGQARALICMGGNFALAMPDREASAVPL
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCCCCH
TQLDLAVHVATKLNRSHLLTARHSYILPVLGRSEIDMQKSGAQAVTVEDSMSMIHASRGV
HHHHHHHHHHHHCCHHHEEEECCCEEEEECCCCCCCHHHCCCCEEEEHHHHHHHHHHCCC
LKPAGVMLKSECAVVAGIAQATLPQSVVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRH
CCCCCCEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
PGGFHLINAAAERRWMTPSGKANFITSKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGM
CCCEEEEEHHHHCCCCCCCCCCCEEECCCCCCCCHHHHCCEEEEEEECCCCCCCCEEEEC
DDRYRGVFGQRDVVFMSAKQAKICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMAD
CCHHCCCCCCCCEEEEECCCCEEEEECCCCEEEEEEECCCCCHHHHHHCEEEEEEEECCC
RSLVTYFPESNHMLTLDNHDPLSGIPGYKSIPVELEPSN
CCEEEECCCCCCEEEECCCCCCCCCCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796