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The map label for this gene is yihQ [H]

Identifier: 209398541

GI number: 209398541

Start: 4966150

End: 4968186

Strand: Reverse

Name: yihQ [H]

Synonym: ECH74115_5324

Alternate gene names: 209398541

Gene position: 4968186-4966150 (Counterclockwise)

Preceding gene: 209396303

Following gene: 209399281

Centisome position: 89.16

GC content: 53.51

Gene sequence:

>2037_bases
ATGGATACGCCACGCCCACAATTACCAGATTTTGAATTTCATCAGAATAACGACAGTTTTACCCTACATTTTCGACAACG
TCTTATTTTAACCCATAGCAAAGATAATCCTTGTTTATGGATTGGCTCAGGTATAGCGGACATCGATATGTTCCGCGGCA
ATTTCAGCATTAAAGATAAACTACAGGAGAAAATTGCGCTTACCGACGCCATCGTCAGCCAGTCACCGGATGGTTGGTTA
ATCCATTTCAGTCGTGGTTCTGACATTAGCGCCACGCTGAATATCTCTGCCGACGATCAGGGCCGTTTATTGCTGGAACT
ACAAAACGACAACCTTAACCACAACCGCATCTGGCTGCGCCTTGCCGCTCAACCAGAGGACCATATCTACGGCTGCGGCG
AACAGTTTTCCTACTTCGATCTGCGCGGCAAACCGTTCCCGCTATGGACCAGTGAACAAGGCGTTGGTCGCAACAAACAA
ACCTATGTCACCTGGCAGGCCGACTGCAAAGAAAATGCGGGCGGCGACTATTACTGGACTTTCTTCCCACAGCCTACGTT
TGTCAGCACGCAGAAGTATTATTGCCATGTTGATAACAGTTGCTATATGAACTTCGACTTTAGTGCCCCGGAATACCATG
AACTGGCGCTGTGGGAAGACAAAGCAACGCTGCGTTTTGAATGTGCTGACACATACATCTCCCTGCTGGAAAAATTAACC
GCCCTGCTGGGACGCCAGCCAGAACTGCCCGACTGGATTTATGACGGAGTAACGCTCGGCATTCAGGGCGGGACGGAAGT
GTGCCAGAAGAAACTGGACACCATGCGTAACGCGGGCGTGAAGGTCAACGGCATCTGGGCGCAGGACTGGTCCGGTATTC
GTATGACCTCTTTTGGCAAACGCGTGATGTGGAACTGGAAGTGGAACAGCGAAAACTACCCGCAACTGGATTCGCGTATC
AAGCAGTGGAACAAAGAGGGCGTGCAGTTCCTTGCCTATATCAACCCGTATGTTGCCAGTGATAAAGATCTCTGCGAAGA
GGCGGCAAAGCGCGGTTATCTGGCAAAAGATGTCGCCGGTGGCGACTATCTGGTGGAGTTTGGCGAGTTCTACGGCGGCG
TTGTCGATCTCACCAATCCGGAAGCCTACGCCTGGTTCAAGGAAGTTATCAAAAAGAACATGATTGAACTCGGCTGCGGC
GGCTGGATGGCTGACTTCGGCGAGTATCTGCCCACCGACACGTACCTGCATAACGGCATCAGCGCGGAAATTATGCATAA
CGCCTGGCCCGCGCTGTGGGCGAAATGTAACTACGAAGCCCTTGAAGAAACGGGCAAGCTCGGCGAGATCCTCTTCTTTA
TGCGCGCCGGTTCTACCGGTAGCCAGAAATACTCCACCATGATGTGGGCGGGTGACCAGAACGTGGACTGGAGTCTGGAC
GATGGCCTGGCGTCGGTTGTCCCGGCGGCGCTATCTCTGGCAATGACCGGACATGGCCTGCATCACAGCGACATTGGCGG
TTATACCACCCTGTTTGAGATGAAGCGCAGCAAAGAGCTGCTGCTGCGCTGGTGCGATTTCAGCGCCTTCACGCCGATGA
TGCGCACCCACGAAGGTAACCGTCCTGGCGACAACTGGCAGTTTGACGGCGACGCGGAAACCATCGCCCATTTCGCCCGT
ATGACCACCGTCTTCACCACCCTGAAACCTTACCTGAAAGAGGCCGTCGCGCTGAATGCGAAGTCCGGCCTGCCGGTTAT
GCGCCCGCTGTTCCTGCATTACGAAGACGACGCGCAGACCTATTCCCTGAAATATCAGTACCTGTTAGGTCGCGACATTC
TGGTTGCTCCGGTACACGAAGAAGGTCGCAGCGACTGGACGCTCTATCTGCCAGAGGATAACTGGGTCCACGCCTGGACC
GGAGAAACCTTCCACGGTGGAGAAATAACTGTTGAAGCGCCCATCGGCAAGCCGCCGGTCTTTTATCGCGCCGACAGCGA
ATGGGCTGCACTGTTCGCCTCGTTAAAAAACATCTAA

Upstream 100 bases:

>100_bases
TGCGGGTTTAAATTTATATCCGCACACATTCTTTAATTAATTAAACCTGTAATAACAGGATGGCATGAAATATTAGCTTT
ATACTCTATGGAGATTATTT

Downstream 100 bases:

>100_bases
TCATGCCCGCCCGTGGGGAAACTCACGGGCAAATGGAGAATAACGATGAGTCACATCACAACGGAAGATCCGGCAACTTT
GCGCCTGCCCTTTAAAGAGA

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MDTPRPQLPDFEFHQNNDSFTLHFRQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWL
IHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRI
KQWNKEGVQFLAYINPYVASDKDLCEEAAKRGYLAKDVAGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCG
GWMADFGEYLPTDTYLHNGISAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQTYSLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWT
GETFHGGEITVEAPIGKPPVFYRADSEWAALFASLKNI

Sequences:

>Translated_678_residues
MDTPRPQLPDFEFHQNNDSFTLHFRQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWL
IHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRI
KQWNKEGVQFLAYINPYVASDKDLCEEAAKRGYLAKDVAGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCG
GWMADFGEYLPTDTYLHNGISAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQTYSLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWT
GETFHGGEITVEAPIGKPPVFYRADSEWAALFASLKNI
>Mature_678_residues
MDTPRPQLPDFEFHQNNDSFTLHFRQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWL
IHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRI
KQWNKEGVQFLAYINPYVASDKDLCEEAAKRGYLAKDVAGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCG
GWMADFGEYLPTDTYLHNGISAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQTYSLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWT
GETFHGGEITVEAPIGKPPVFYRADSEWAALFASLKNI

Specific function: Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed [H]

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI153791946, Length=349, Percent_Identity=24.9283667621776, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI88900491, Length=385, Percent_Identity=25.1948051948052, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI38202257, Length=385, Percent_Identity=25.1948051948052, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI66346737, Length=397, Percent_Identity=25.9445843828715, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI119393895, Length=407, Percent_Identity=22.8501228501229, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI119393893, Length=407, Percent_Identity=22.8501228501229, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI119393891, Length=407, Percent_Identity=22.8501228501229, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI221316699, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI310115361, Length=236, Percent_Identity=28.8135593220339, Blast_Score=77, Evalue=6e-14,
Organism=Escherichia coli, GI2367323, Length=678, Percent_Identity=97.6401179941003, Blast_Score=1392, Evalue=0.0,
Organism=Escherichia coli, GI2367256, Length=550, Percent_Identity=24.5454545454545, Blast_Score=176, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17560800, Length=380, Percent_Identity=23.1578947368421, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560798, Length=380, Percent_Identity=23.1578947368421, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71991189, Length=342, Percent_Identity=24.8538011695906, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32563849, Length=231, Percent_Identity=30.7359307359307, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71985706, Length=237, Percent_Identity=28.6919831223629, Blast_Score=80, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319706, Length=381, Percent_Identity=22.5721784776903, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24650054, Length=345, Percent_Identity=25.7971014492754, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24643749, Length=357, Percent_Identity=24.0896358543417, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24643753, Length=357, Percent_Identity=24.0896358543417, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24643751, Length=357, Percent_Identity=24.0896358543417, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24643746, Length=357, Percent_Identity=24.0896358543417, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21357605, Length=357, Percent_Identity=24.0896358543417, Blast_Score=83, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 77378; Mature: 77378

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPRPQLPDFEFHQNNDSFTLHFRQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDK
CCCCCCCCCCCCEECCCCCEEEEEEEEEEEEECCCCCEEEEECCCCEEEEECCCCCHHHH
LQEKIALTDAIVSQSPDGWLIHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLR
HHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEE
LAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQTYVTWQADCKENAGGDYYWT
EECCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEE
FFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ECCCCCEEECCEEEEEECCEEEEEECCCCCCCEEEEEEECCCEEEEEEHHHHHHHHHHHH
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGK
HHHCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEECCCC
RVMWNWKWNSENYPQLDSRIKQWNKEGVQFLAYINPYVASDKDLCEEAAKRGYLAKDVAG
EEEEEEEECCCCCCHHHHHHHHHCHHHEEEEEEECCCCCCCHHHHHHHHHCCCEEEECCC
GDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCGGWMADFGEYLPTDTYLHNGI
CHHEEEHHHHCCCEEECCCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCHHHHCCC
SAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
CHHHHHCCCHHHHHCCCHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCC
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGN
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHCCCC
RPGDNWQFDGDAETIAHFARMTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCEE
YSLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWTGETFHGGEITVEAPIGKPPV
EEEEEEEEECCCEEEEECCCCCCCCEEEECCCCCEEEEECCCEEECCEEEEECCCCCCCE
FYRADSEWAALFASLKNI
EEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MDTPRPQLPDFEFHQNNDSFTLHFRQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDK
CCCCCCCCCCCCEECCCCCEEEEEEEEEEEEECCCCCEEEEECCCCEEEEECCCCCHHHH
LQEKIALTDAIVSQSPDGWLIHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLR
HHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEE
LAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQTYVTWQADCKENAGGDYYWT
EECCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEE
FFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ECCCCCEEECCEEEEEECCEEEEEECCCCCCCEEEEEEECCCEEEEEEHHHHHHHHHHHH
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGK
HHHCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEECCCC
RVMWNWKWNSENYPQLDSRIKQWNKEGVQFLAYINPYVASDKDLCEEAAKRGYLAKDVAG
EEEEEEEECCCCCCHHHHHHHHHCHHHEEEEEEECCCCCCCHHHHHHHHHCCCEEEECCC
GDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCGGWMADFGEYLPTDTYLHNGI
CHHEEEHHHHCCCEEECCCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCHHHHCCC
SAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
CHHHHHCCCHHHHHCCCHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCC
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGN
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHCCCC
RPGDNWQFDGDAETIAHFARMTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCEE
YSLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWTGETFHGGEITVEAPIGKPPV
EEEEEEEEECCCEEEEECCCCCCCCEEEECCCCCEEEEECCCEEECCEEEEECCCCCCCE
FYRADSEWAALFASLKNI
EEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]