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The map label for this gene is yihP [H]

Identifier: 209399281

GI number: 209399281

Start: 4964719

End: 4966104

Strand: Reverse

Name: yihP [H]

Synonym: ECH74115_5323

Alternate gene names: 209399281

Gene position: 4966104-4964719 (Counterclockwise)

Preceding gene: 209398541

Following gene: 209399685

Centisome position: 89.12

GC content: 52.67

Gene sequence:

>1386_bases
ATGAGTCACATCACAACGGAAGATCCGGCAACTTTGCGCCTGCCCTTTAAAGAGAAACTCTCTTACGGTATCGGCGATCT
GGCCTCTAACATCCTGCTGGATATTGGTACGCTTTATCTTTTGAAGTTTTATACCGACGTTCTGGGGCTACCTGGCACCT
ATGGCGGCATTATCTTTTTGATCTCGAAATTCTTTACCGCCTTTACCGATATGGGAACCGGCATCATGTTGGATTCCCGG
CGTAAGATTGGCCCGAAAGGTAAGTTCCGCCCTTTCATTTTGTACGCGTCATTCCCGGTCACCTTATTGGCAATCGCTAA
CTTTATCGGCACACCGTTCGATGTCACTGGTAAAACGGTGATGGCCACTATTCTGTTTATGCTCTACGGGCTGTTTTTCA
GCATGATGAACTGCTCCTATGGCGCGATGGTGCCTGCTATTACCAAAAACCCCAACGAGCGCGCATCACTGGCGGCATGG
CGTCAGGGAGGCGCTACGCTGGGCCTGCTGCTGTGCACGGTGGGATTCGTGCCGGTTATGAATCTTATCGAAGGTAATCA
GCAACTTGGCTATATCTTCGCCGCCACGCTGTTTTCACTGTTCGGCCTGCTGTTTATGTGGATCTGCTACTCGGGCGTGA
AAGAGCGTTATGTCGAAACCCAACCAGCCAATCCGGCGCAAAAGCCTGGCCTGCTGCAATCTTTCCGCGCAATTGCCGGT
AACCGCCCACTGTTCATTCTGTGCATTGCCAACCTCTGCACTTTAGGGGCGTTTAACGTCAAGCTCGCCATCCAGGTCTA
TTACACCCAGTACGTACTTAACGATCCCATCCTGTTGTCATATATGGGATTTTTCAGCATGGGCTGTATTTTCATCGGTG
TGTTCCTGATGCCTGGCGCAGTCAGGCGTTTTGGTAAGAAGAAGGTCTATATCGGCGGCCTACTGATTTGGGTGCTGGGC
GATCTGCTCAACTATTTCTTCAGCGGCGGTTCGGTCAGCTTCGTGGCGTTCTCCTGCCTGGCATTCTTCGGCTCAGCGTT
TGTTAACAGCCTGAACTGGGCGCTGGTTTCCGACACCGTCGAGTACGGCGAGTGGCGTACCGGCGTTCGTTCGGAAGGAA
CGGTCTACACCGGCTTCACCTTCTTTCGCAAAGTGTCTCAGGCGCTGGCTGGTTTCTTCCCCGGCTGGATGCTGACGCAA
ATCGGTTATGTGCCGAACGTGGCGCAGGCTGACCACACCATTGAAGGGTTGCGCCAGCTGATCTTCATCTACCCAAGCGC
ACTGGCGGTAGTCACCATTGTGGCGATGGGCTGCTTCTACAGCCTGAACGAGAAGATGTATGTCCGCATTGTTGAAGAAA
TAGAAGCCCGTAAACGCACGGCGTAA

Upstream 100 bases:

>100_bases
TTATCGCGCCGACAGCGAATGGGCTGCACTGTTCGCCTCGTTAAAAAACATCTAATCATGCCCGCCCGTGGGGAAACTCA
CGGGCAAATGGAGAATAACG

Downstream 100 bases:

>100_bases
TAATAAACAATGCCCTGCGGGGCGTTATAAGGAGTGATTATGTCTGACCATAATCCACTGACATTAAAACTGAATCTGCG
GGAAAAAATCGCCTATGGTA

Product: sugar transporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSR
RKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAW
RQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPANPAQKPGLLQSFRAIAG
NRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVLG
DLLNYFFSGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQ
IGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA

Sequences:

>Translated_461_residues
MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSR
RKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAW
RQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPANPAQKPGLLQSFRAIAG
NRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVLG
DLLNYFFSGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQ
IGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA
>Mature_460_residues
SHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSRR
KIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAWR
QGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPANPAQKPGLLQSFRAIAGN
RPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVLGD
LLNYFFSGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQI
GYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI122937339, Length=448, Percent_Identity=24.3303571428571, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI145693206, Length=461, Percent_Identity=99.1323210412148, Blast_Score=929, Evalue=0.0,
Organism=Escherichia coli, GI48994989, Length=456, Percent_Identity=64.6929824561403, Blast_Score=619, Evalue=1e-178,
Organism=Escherichia coli, GI1787902, Length=453, Percent_Identity=33.3333333333333, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI87082306, Length=451, Percent_Identity=29.0465631929047, Blast_Score=178, Evalue=8e-46,
Organism=Escherichia coli, GI1786466, Length=420, Percent_Identity=27.6190476190476, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1790561, Length=447, Percent_Identity=26.3982102908277, Blast_Score=141, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50997; Mature: 50866

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00872 NA_GALACTOSIDE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFL
CCCCCCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTV
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCHHHH
MATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAWRQGGATLGLLLCTVGFVPVM
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
NLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPANPAQKPGLLQSFRAIAG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHC
NRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGA
CCCEEEHHHHHHHHCCCCCEEEEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHH
VRRFGKKKVYIGGLLIWVLGDLLNYFFSGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTV
HHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQIGYVPNVAQADHTIEGLRQL
HHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHH
IFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFL
CCCCCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTV
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCHHHH
MATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAWRQGGATLGLLLCTVGFVPVM
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
NLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPANPAQKPGLLQSFRAIAG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHC
NRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGA
CCCEEEHHHHHHHHCCCCCEEEEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHH
VRRFGKKKVYIGGLLIWVLGDLLNYFFSGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTV
HHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQIGYVPNVAQADHTIEGLRQL
HHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHH
IFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]