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The map label for this gene is argJ

Identifier: 20808852

GI number: 20808852

Start: 2386496

End: 2387707

Strand: Reverse

Name: argJ

Synonym: TTE2497

Alternate gene names: 20808852

Gene position: 2387707-2386496 (Counterclockwise)

Preceding gene: 20808853

Following gene: 20808851

Centisome position: 88.78

GC content: 39.77

Gene sequence:

>1212_bases
ATGGAGATTTTAGATGGGAAAATAGAATTGCCCAAAGGTTTTGTGGCTTCAGGTGTATTTGCAGGCATAAAGAGAAGTAA
GAAGGATTTGGCTTTAATATATTCTGAGCGATTGGCGAACATATCGGCAGTGTTTACTACAAACAGGGTAAAAGCAGCTC
CTGTCATTCTAGATATGGAGAGGGCAAAAAAGGGGAAAGCCCAGGCAATTGTAATAAATAGCGGCAATGCAAATGCGTGT
ACAGGGGAGAAAGGAATTGAGGACGCAAAATCTATGGCAAAAAAGGTAGCAGAAGTCCTCGAGATAGAGGAAGAAGATGT
CCTAGTTTGTTCTACAGGAGTGATTGGCGTACCTCTTCCAATGGAAAAAGTGTTGAAAGGAATTGAAGTGGCGGCATTGA
GCCTATCAAAAGAAGGAGGATATGATGCAGCCCATGCTATTATGACGACAGATACATTTTTGAAGGCTGTTACTGTGAAA
TTTAATGTTGAAGGAAAAGATATTACAATGACAGGTTTTGCAAAAGGTTCCGGAATGATACATCCTAATATGGCTACAAT
GCTTTCTTTTGTACTTACAGATGCCAGTGTGGAGAAGGCTACGTTGGATAAAGCCTTTAAAAATACTGTCAATAGGACTT
ATAACATGATTTCTGTTGATGGGGATATGAGCACAAATGATACTGCGATAGTGATGGCAAATGGAATGGCAGAAAATAAA
GCCATTCAGGAGGGGACCTATGAATTTGATTTATTTTACAAAGCCTTGGAATACGTCAATAAAACTCTTGCCAGACTCAT
CGCAAAAGACGGTGAGGGAGCGACTAAGCTTATAGAAGTAAATGTAATAAATGCTAAGACGGAAAATGACGCAAGACTTG
CAGCTAAAGCCATTGTAAATTCAAACCTTGTGAAGACAGCTATCTTTGGGGAAGATGCCAACTGGGGAAGGATACTGGCA
GCAGTGGGCTATTCTGGAGCAGACTTTGATGTGGACAAAGTGGACATATATCTAAAAAGCGCAAAAGGGGAAGTTAAGGT
TTGTGAAAATGGCAGTTTTTTTGCCTTTGATGAATCTTTAGCTAAGGAAGTTTTGAAAGAAAAGGAAATTTTCATAATAG
TTGACATGAAAGCCGGAGAATTTATGGCTACTTCATGGGGATGCGACCTCTCTTACGATTATGTAAAAATAAATGGGAGC
TACAGGACATGA

Upstream 100 bases:

>100_bases
GTTCGAAATAGAAGAAAAAGCAGGGCTTGATATAGTGCCAGTATATCCATAAATAAAGCATTAGTATTAGAAGGGGTGTA
AGAACGAGGCGATGGAGCAG

Downstream 100 bases:

>100_bases
TAAGGAAAGAAAAATTCGGAGATGAAATTTTAAAAGCACATATCCTTGTGGAGGCGCTCCCCTATATAAAAAAATTCTCC
GGCAAGACAGTTGTGATAAA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MEILDGKIELPKGFVASGVFAGIKRSKKDLALIYSERLANISAVFTTNRVKAAPVILDMERAKKGKAQAIVINSGNANAC
TGEKGIEDAKSMAKKVAEVLEIEEEDVLVCSTGVIGVPLPMEKVLKGIEVAALSLSKEGGYDAAHAIMTTDTFLKAVTVK
FNVEGKDITMTGFAKGSGMIHPNMATMLSFVLTDASVEKATLDKAFKNTVNRTYNMISVDGDMSTNDTAIVMANGMAENK
AIQEGTYEFDLFYKALEYVNKTLARLIAKDGEGATKLIEVNVINAKTENDARLAAKAIVNSNLVKTAIFGEDANWGRILA
AVGYSGADFDVDKVDIYLKSAKGEVKVCENGSFFAFDESLAKEVLKEKEIFIIVDMKAGEFMATSWGCDLSYDYVKINGS
YRT

Sequences:

>Translated_403_residues
MEILDGKIELPKGFVASGVFAGIKRSKKDLALIYSERLANISAVFTTNRVKAAPVILDMERAKKGKAQAIVINSGNANAC
TGEKGIEDAKSMAKKVAEVLEIEEEDVLVCSTGVIGVPLPMEKVLKGIEVAALSLSKEGGYDAAHAIMTTDTFLKAVTVK
FNVEGKDITMTGFAKGSGMIHPNMATMLSFVLTDASVEKATLDKAFKNTVNRTYNMISVDGDMSTNDTAIVMANGMAENK
AIQEGTYEFDLFYKALEYVNKTLARLIAKDGEGATKLIEVNVINAKTENDARLAAKAIVNSNLVKTAIFGEDANWGRILA
AVGYSGADFDVDKVDIYLKSAKGEVKVCENGSFFAFDESLAKEVLKEKEIFIIVDMKAGEFMATSWGCDLSYDYVKINGS
YRT
>Mature_403_residues
MEILDGKIELPKGFVASGVFAGIKRSKKDLALIYSERLANISAVFTTNRVKAAPVILDMERAKKGKAQAIVINSGNANAC
TGEKGIEDAKSMAKKVAEVLEIEEEDVLVCSTGVIGVPLPMEKVLKGIEVAALSLSKEGGYDAAHAIMTTDTFLKAVTVK
FNVEGKDITMTGFAKGSGMIHPNMATMLSFVLTDASVEKATLDKAFKNTVNRTYNMISVDGDMSTNDTAIVMANGMAENK
AIQEGTYEFDLFYKALEYVNKTLARLIAKDGEGATKLIEVNVINAKTENDARLAAKAIVNSNLVKTAIFGEDANWGRILA
AVGYSGADFDVDKVDIYLKSAKGEVKVCENGSFFAFDESLAKEVLKEKEIFIIVDMKAGEFMATSWGCDLSYDYVKINGS
YRT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=416, Percent_Identity=41.5865384615385, Blast_Score=286, Evalue=5e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_THETN (Q8R7B9)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_624023.1
- ProteinModelPortal:   Q8R7B9
- SMR:   Q8R7B9
- MEROPS:   T05.001
- GeneID:   998004
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE2497
- NMPDR:   fig|273068.3.peg.1895
- HOGENOM:   HBG284202
- OMA:   VHENSAY
- ProtClustDB:   PRK05388
- BioCyc:   TTEN273068:TTE2497-MONOMER
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 43521; Mature: 43521

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILDGKIELPKGFVASGVFAGIKRSKKDLALIYSERLANISAVFTTNRVKAAPVILDME
CCCCCCEEECCCCHHHHHHHHHHHCCCCHHEEHHHHHHCCEEEEEEECCCEECEEEEEHH
RAKKGKAQAIVINSGNANACTGEKGIEDAKSMAKKVAEVLEIEEEDVLVCSTGVIGVPLP
HCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEECCCC
MEKVLKGIEVAALSLSKEGGYDAAHAIMTTDTFLKAVTVKFNVEGKDITMTGFAKGSGMI
HHHHHCCCEEEEEEECCCCCCCHHHEEEEHHHEEEEEEEEEEECCCEEEEEEEECCCCEE
HPNMATMLSFVLTDASVEKATLDKAFKNTVNRTYNMISVDGDMSTNDTAIVMANGMAENK
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEECCCCCCC
AIQEGTYEFDLFYKALEYVNKTLARLIAKDGEGATKLIEVNVINAKTENDARLAAKAIVN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHC
SNLVKTAIFGEDANWGRILAAVGYSGADFDVDKVDIYLKSAKGEVKVCENGSFFAFDESL
CCCEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCEEEECCCCEEEECHHH
AKEVLKEKEIFIIVDMKAGEFMATSWGCDLSYDYVKINGSYRT
HHHHHCCCCEEEEEEECCCCEEEEECCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MEILDGKIELPKGFVASGVFAGIKRSKKDLALIYSERLANISAVFTTNRVKAAPVILDME
CCCCCCEEECCCCHHHHHHHHHHHCCCCHHEEHHHHHHCCEEEEEEECCCEECEEEEEHH
RAKKGKAQAIVINSGNANACTGEKGIEDAKSMAKKVAEVLEIEEEDVLVCSTGVIGVPLP
HCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEECCCC
MEKVLKGIEVAALSLSKEGGYDAAHAIMTTDTFLKAVTVKFNVEGKDITMTGFAKGSGMI
HHHHHCCCEEEEEEECCCCCCCHHHEEEEHHHEEEEEEEEEEECCCEEEEEEEECCCCEE
HPNMATMLSFVLTDASVEKATLDKAFKNTVNRTYNMISVDGDMSTNDTAIVMANGMAENK
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEECCCCCCC
AIQEGTYEFDLFYKALEYVNKTLARLIAKDGEGATKLIEVNVINAKTENDARLAAKAIVN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHC
SNLVKTAIFGEDANWGRILAAVGYSGADFDVDKVDIYLKSAKGEVKVCENGSFFAFDESL
CCCEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCEEEECCCCEEEECHHH
AKEVLKEKEIFIIVDMKAGEFMATSWGCDLSYDYVKINGSYRT
HHHHHCCCCEEEEEEECCCCEEEEECCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336