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The map label for this gene is argC

Identifier: 20808853

GI number: 20808853

Start: 2387756

End: 2388790

Strand: Reverse

Name: argC

Synonym: TTE2498

Alternate gene names: 20808853

Gene position: 2388790-2387756 (Counterclockwise)

Preceding gene: 20808854

Following gene: 20808852

Centisome position: 88.82

GC content: 38.74

Gene sequence:

>1035_bases
ATGATAAAAGTTGGGATATTTGGAGCAACTGGATACACTGGAGTAGAGCTTATGCGCCTTCTTTCAAAGCATGAAAAAGT
AAAAATAGAGTACATTTCGTCTCAAAGTTATGCAGGAAAGTCAATAGCAGATGTCTATCCATCCCTTACAGGGTTTTATG
ACATTTCTCTCGATGATGTAGAGGTAGAGAAGGCGGTTTCAAAGTGCGATGTAGTTTTTACGGCGCTACCTGCAGGTTAT
GCTTCTAAAATTGCAAGGGAAGCGGTAAAAAAAGGGGTTAAAGTGATTGATTTGGGGGCAGATTTCAGATTTGACGATTA
TTCGACTTATAAAGAATGGTATGGCGGAGAATACGATGGGTATGATGGGATAAAAAGAGCGTATGGCTTACCTGAGATTT
ATAGAGATAGTATAAAAGAAGCCGATGTAGTGGGAAATCCAGGGTGCTATCCTACTAGTGTGATATTAGGGCTTGTTCCT
CTTTTGAAAGAGAAGGTTATAGATGGAAACATAATTATTGATTCAAAATCGGGGATATCGGGAGCAGGCCACAGCCCGTC
ACAGAAGAATATATATGCAGAATGTAATGAAAGTATAAGAGCATACAATGTGGCAAATCACAGGCATGTGCCCGAGATGG
TTCAGGAACTTTCCAAGGCATCGGGAGAAAAGGTATCGGTGGTTTTTGCACCTCACTTGACACCTATGACCAGGGGAATT
TTGAGTACAATGTATTGCAAGCTAAGAGAAAATTTAAATCAAGAGGAAATTTATGAGGTTTTCGCTGAATTTTATAAAAA
TGAGTATTTTGTGAAGGTGCTAAAGCCTGGGGCTTATCCTTCTACTAAAAATGTATATGGTTCGAATTTTTGTCACATAG
GTTTTGAAGTTGACAAAGCGACAGGTACTTTAGTTGTAATGACTGCCATTGATAACTTAGTAAAAGGAGCATCAGGTCAA
GCGATACAGAATATGAACATAATGTTCGAAATAGAAGAAAAAGCAGGGCTTGATATAGTGCCAGTATATCCATAA

Upstream 100 bases:

>100_bases
TATAAATTAAATAGTTTATTTATGCAGCAATTATTTTTTTACGAATTTTTGCATAAATATAAATTAAACTGTATATATAT
TTACAAGGGGAGGCAGCCGG

Downstream 100 bases:

>100_bases
ATAAAGCATTAGTATTAGAAGGGGTGTAAGAACGAGGCGATGGAGCAGATGGAGATTTTAGATGGGAAAATAGAATTGCC
CAAAGGTTTTGTGGCTTCAG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MIKVGIFGATGYTGVELMRLLSKHEKVKIEYISSQSYAGKSIADVYPSLTGFYDISLDDVEVEKAVSKCDVVFTALPAGY
ASKIAREAVKKGVKVIDLGADFRFDDYSTYKEWYGGEYDGYDGIKRAYGLPEIYRDSIKEADVVGNPGCYPTSVILGLVP
LLKEKVIDGNIIIDSKSGISGAGHSPSQKNIYAECNESIRAYNVANHRHVPEMVQELSKASGEKVSVVFAPHLTPMTRGI
LSTMYCKLRENLNQEEIYEVFAEFYKNEYFVKVLKPGAYPSTKNVYGSNFCHIGFEVDKATGTLVVMTAIDNLVKGASGQ
AIQNMNIMFEIEEKAGLDIVPVYP

Sequences:

>Translated_344_residues
MIKVGIFGATGYTGVELMRLLSKHEKVKIEYISSQSYAGKSIADVYPSLTGFYDISLDDVEVEKAVSKCDVVFTALPAGY
ASKIAREAVKKGVKVIDLGADFRFDDYSTYKEWYGGEYDGYDGIKRAYGLPEIYRDSIKEADVVGNPGCYPTSVILGLVP
LLKEKVIDGNIIIDSKSGISGAGHSPSQKNIYAECNESIRAYNVANHRHVPEMVQELSKASGEKVSVVFAPHLTPMTRGI
LSTMYCKLRENLNQEEIYEVFAEFYKNEYFVKVLKPGAYPSTKNVYGSNFCHIGFEVDKATGTLVVMTAIDNLVKGASGQ
AIQNMNIMFEIEEKAGLDIVPVYP
>Mature_344_residues
MIKVGIFGATGYTGVELMRLLSKHEKVKIEYISSQSYAGKSIADVYPSLTGFYDISLDDVEVEKAVSKCDVVFTALPAGY
ASKIAREAVKKGVKVIDLGADFRFDDYSTYKEWYGGEYDGYDGIKRAYGLPEIYRDSIKEADVVGNPGCYPTSVILGLVP
LLKEKVIDGNIIIDSKSGISGAGHSPSQKNIYAECNESIRAYNVANHRHVPEMVQELSKASGEKVSVVFAPHLTPMTRGI
LSTMYCKLRENLNQEEIYEVFAEFYKNEYFVKVLKPGAYPSTKNVYGSNFCHIGFEVDKATGTLVVMTAIDNLVKGASGQ
AIQNMNIMFEIEEKAGLDIVPVYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=344, Percent_Identity=35.1744186046512, Blast_Score=192, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6320913, Length=340, Percent_Identity=31.4705882352941, Blast_Score=132, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_THETN (Q8R7B8)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_624024.1
- ProteinModelPortal:   Q8R7B8
- SMR:   Q8R7B8
- GeneID:   995991
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE2498
- NMPDR:   fig|273068.3.peg.1896
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   TTEN273068:TTE2498-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37944; Mature: 37944

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVGIFGATGYTGVELMRLLSKHEKVKIEYISSQSYAGKSIADVYPSLTGFYDISLDDV
CEEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHCCCCCCEEECCCCCH
EVEKAVSKCDVVFTALPAGYASKIAREAVKKGVKVIDLGADFRFDDYSTYKEWYGGEYDG
HHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHCCCCCCC
YDGIKRAYGLPEIYRDSIKEADVVGNPGCYPTSVILGLVPLLKEKVIDGNIIIDSKSGIS
CHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
GAGHSPSQKNIYAECNESIRAYNVANHRHVPEMVQELSKASGEKVSVVFAPHLTPMTRGI
CCCCCCCCCCHHHHHCCCHHEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHH
LSTMYCKLRENLNQEEIYEVFAEFYKNEYFVKVLKPGAYPSTKNVYGSNFCHIGFEVDKA
HHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEECC
TGTLVVMTAIDNLVKGASGQAIQNMNIMFEIEEKAGLDIVPVYP
CCCEEEHHHHHHHHCCCCCCEEECCEEEEEECCCCCCCEEECCC
>Mature Secondary Structure
MIKVGIFGATGYTGVELMRLLSKHEKVKIEYISSQSYAGKSIADVYPSLTGFYDISLDDV
CEEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHCCCCCCEEECCCCCH
EVEKAVSKCDVVFTALPAGYASKIAREAVKKGVKVIDLGADFRFDDYSTYKEWYGGEYDG
HHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHCCCCCCC
YDGIKRAYGLPEIYRDSIKEADVVGNPGCYPTSVILGLVPLLKEKVIDGNIIIDSKSGIS
CHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
GAGHSPSQKNIYAECNESIRAYNVANHRHVPEMVQELSKASGEKVSVVFAPHLTPMTRGI
CCCCCCCCCCHHHHHCCCHHEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHH
LSTMYCKLRENLNQEEIYEVFAEFYKNEYFVKVLKPGAYPSTKNVYGSNFCHIGFEVDKA
HHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEECC
TGTLVVMTAIDNLVKGASGQAIQNMNIMFEIEEKAGLDIVPVYP
CCCEEEHHHHHHHHCCCCCCEEECCEEEEEECCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336