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The map label for this gene is MtlD2 [H]

Identifier: 20808344

GI number: 20808344

Start: 1884724

End: 1886343

Strand: Reverse

Name: MtlD2 [H]

Synonym: TTE1940

Alternate gene names: 20808344

Gene position: 1886343-1884724 (Counterclockwise)

Preceding gene: 20808345

Following gene: 20808343

Centisome position: 70.14

GC content: 34.69

Gene sequence:

>1620_bases
ATGCTACTGACAAGGGAAGGTATAAAAGATGTTGAAAAATGGCGGAGTCGAGGCATAAAACTTCCCAACTACGATGTTGA
GGAGATTTCAAAAAGAACCAAAGAAAGTCCAATTTGGCTACATTTTGGAGCAGGGAACATTTTTAGAGGATTTATAGCAC
TTCTACAACAGAATCTTTTAGATAAAGGACTTATTGATAAAGGAATTATAGCAGTGGAGTCATATGATTATGAAATAATT
GAAAAAATATATGTTCCTTATGACAATTTAAGTATGCTAGTAGTCATGAACATAGATGGAACACTTGAAATAGAAGTCAT
AGGCAGTATAAGCGATAAAATAATAGCCGATCCATCACATAGTGATTGGGAAAGATTGAAAAACATCTTTTCGAATCCAT
CACTGCAGATAGCAAGTTTTACAATAACAGAAAAAGCTTATAACTTAAAAGACTTTTCAGGTGAATATATAAAAGATGTA
AAAGAAGACATAGAGGAAGGTCTGGATAAACCTAAACACATCATTTCAAAAGTAACTTCCTTACTCTATGAAAGATACAA
AGCAGGAAAATATCCTCTTGCTCTTTTGAGTTTAGACAATTTCTCTGGAAATGGAGAAAGACTTTTCAATTCGATAAAGA
CTATCGCAGAAGAATGGATAAAAAAAGGTTTTGTTGAAGAGGGATTTTTGAATTACTTAACAGATTCTACAAAAGTATCT
TTCCCGCTTAGTATGATAGATAAAATAGTGCCAAGGCCTTCAGAAGAGGTGAAAAAGAAGTTAGAAGACCTTGGCATAGA
GAGAATGGACATAATCAAAACCAGTAAAAACACTATAATAGCGCCTTTTGTAAATGCTGAAAAAATACACTACCTAGTGA
TAGAAGACAAGTTCCCTAATGGCAGGCCTCCATTAGAAGAGGCAGGAGTGATTTTTACAGATAAAGAAACAGTAGAAAAA
GTAGAGAGGATGAAAGTGACAACCTGTTTAAATCCTTTGCATACAACATTAGCGATTTTTGGTTGTTTGTTAAATTATAG
CACAATAGCAGATGAAATGAAAGATCCATGCCTTAAGAAACTTGTTGAAAAAGTGGGATATGACGAAGGGCTACCTGTAG
TTGTTCATCCAGGTGTGTTAGACCCAGAAGAATTCTTAAGAGAAGTAATTGAGGTGAGATTTCCTAATCCGTACATGCCA
GACACTCCGCAAAGGATTGCAACAGACACGTCACAAAAGATAGCAATAAGATTTGGAGAGACGATAAAATCCTATAAACA
AAGGTCAGATTTAAAAGTGACAGACTTAAAATACATTCCTCTTGTGATAGCAGGATGGTTGAGGTATTTAATGGGTTTAG
ATGATGAAGGCAATCCAATGACATTAAGCCCAGACCCATTGCTTGAAGATTTAAGGTCTCACATTTCGAACATAAAATTA
GGTGATGTAGATTCGGTAAAAGACAATTTAAAACCCATTCTTTCAAATGTAAACATTTTTGGCGTTGACCTTTATGAAGT
AGGACTGGGAGAAAGGATAGAAAGTTATTTCAAAGAGTTTATAGAAGGACCAGGTGCAGTGAGAAGAGTATTAGAAAAAT
ATCTTGGATGTAAGGAATGA

Upstream 100 bases:

>100_bases
TAGAATATATATTATTAAACACAAGATAATCCACAAAGTAAAGTGGATATATAATAAAAGAAGCAATATTACAAAGCAAT
TCTAGAAAGGGAGAAGGGAT

Downstream 100 bases:

>100_bases
TGGCAATGAGAAAGTTTATGGATGAAGACTTTTTACTCACAAATGAAACAGCAGTGAAATTGTATCATCAATATGCAAAA
GATATGTCAATTTATGACTT

Product: mannitol-1-phosphate/altronate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MLLTREGIKDVEKWRSRGIKLPNYDVEEISKRTKESPIWLHFGAGNIFRGFIALLQQNLLDKGLIDKGIIAVESYDYEII
EKIYVPYDNLSMLVVMNIDGTLEIEVIGSISDKIIADPSHSDWERLKNIFSNPSLQIASFTITEKAYNLKDFSGEYIKDV
KEDIEEGLDKPKHIISKVTSLLYERYKAGKYPLALLSLDNFSGNGERLFNSIKTIAEEWIKKGFVEEGFLNYLTDSTKVS
FPLSMIDKIVPRPSEEVKKKLEDLGIERMDIIKTSKNTIIAPFVNAEKIHYLVIEDKFPNGRPPLEEAGVIFTDKETVEK
VERMKVTTCLNPLHTTLAIFGCLLNYSTIADEMKDPCLKKLVEKVGYDEGLPVVVHPGVLDPEEFLREVIEVRFPNPYMP
DTPQRIATDTSQKIAIRFGETIKSYKQRSDLKVTDLKYIPLVIAGWLRYLMGLDDEGNPMTLSPDPLLEDLRSHISNIKL
GDVDSVKDNLKPILSNVNIFGVDLYEVGLGERIESYFKEFIEGPGAVRRVLEKYLGCKE

Sequences:

>Translated_539_residues
MLLTREGIKDVEKWRSRGIKLPNYDVEEISKRTKESPIWLHFGAGNIFRGFIALLQQNLLDKGLIDKGIIAVESYDYEII
EKIYVPYDNLSMLVVMNIDGTLEIEVIGSISDKIIADPSHSDWERLKNIFSNPSLQIASFTITEKAYNLKDFSGEYIKDV
KEDIEEGLDKPKHIISKVTSLLYERYKAGKYPLALLSLDNFSGNGERLFNSIKTIAEEWIKKGFVEEGFLNYLTDSTKVS
FPLSMIDKIVPRPSEEVKKKLEDLGIERMDIIKTSKNTIIAPFVNAEKIHYLVIEDKFPNGRPPLEEAGVIFTDKETVEK
VERMKVTTCLNPLHTTLAIFGCLLNYSTIADEMKDPCLKKLVEKVGYDEGLPVVVHPGVLDPEEFLREVIEVRFPNPYMP
DTPQRIATDTSQKIAIRFGETIKSYKQRSDLKVTDLKYIPLVIAGWLRYLMGLDDEGNPMTLSPDPLLEDLRSHISNIKL
GDVDSVKDNLKPILSNVNIFGVDLYEVGLGERIESYFKEFIEGPGAVRRVLEKYLGCKE
>Mature_539_residues
MLLTREGIKDVEKWRSRGIKLPNYDVEEISKRTKESPIWLHFGAGNIFRGFIALLQQNLLDKGLIDKGIIAVESYDYEII
EKIYVPYDNLSMLVVMNIDGTLEIEVIGSISDKIIADPSHSDWERLKNIFSNPSLQIASFTITEKAYNLKDFSGEYIKDV
KEDIEEGLDKPKHIISKVTSLLYERYKAGKYPLALLSLDNFSGNGERLFNSIKTIAEEWIKKGFVEEGFLNYLTDSTKVS
FPLSMIDKIVPRPSEEVKKKLEDLGIERMDIIKTSKNTIIAPFVNAEKIHYLVIEDKFPNGRPPLEEAGVIFTDKETVEK
VERMKVTTCLNPLHTTLAIFGCLLNYSTIADEMKDPCLKKLVEKVGYDEGLPVVVHPGVLDPEEFLREVIEVRFPNPYMP
DTPQRIATDTSQKIAIRFGETIKSYKQRSDLKVTDLKYIPLVIAGWLRYLMGLDDEGNPMTLSPDPLLEDLRSHISNIKL
GDVDSVKDNLKPILSNVNIFGVDLYEVGLGERIESYFKEFIEGPGAVRRVLEKYLGCKE

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=499, Percent_Identity=27.0541082164329, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1790779, Length=495, Percent_Identity=27.4747474747475, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787823, Length=519, Percent_Identity=26.5895953757225, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324401, Length=440, Percent_Identity=29.0909090909091, Blast_Score=136, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6320765, Length=440, Percent_Identity=29.0909090909091, Blast_Score=136, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 61328; Mature: 61328

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00230 MAP1B_NEURAXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTREGIKDVEKWRSRGIKLPNYDVEEISKRTKESPIWLHFGAGNIFRGFIALLQQNLL
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
DKGLIDKGIIAVESYDYEIIEKIYVPYDNLSMLVVMNIDGTLEIEVIGSISDKIIADPSH
HCCCCCCCEEEEECCCHHHHHHHHCCCCCCEEEEEEECCCEEEEEEEECCCCCEEECCCC
SDWERLKNIFSNPSLQIASFTITEKAYNLKDFSGEYIKDVKEDIEEGLDKPKHIISKVTS
HHHHHHHHHHCCCCEEEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
LLYERYKAGKYPLALLSLDNFSGNGERLFNSIKTIAEEWIKKGFVEEGFLNYLTDSTKVS
HHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
FPLSMIDKIVPRPSEEVKKKLEDLGIERMDIIKTSKNTIIAPFVNAEKIHYLVIEDKFPN
CCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHEECCCCEEEEEECCCCEEEEEEEEECCCC
GRPPLEEAGVIFTDKETVEKVERMKVTTCLNPLHTTLAIFGCLLNYSTIADEMKDPCLKK
CCCCHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LVEKVGYDEGLPVVVHPGVLDPEEFLREVIEVRFPNPYMPDTPQRIATDTSQKIAIRFGE
HHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHEEHHHHH
TIKSYKQRSDLKVTDLKYIPLVIAGWLRYLMGLDDEGNPMTLSPDPLLEDLRSHISNIKL
HHHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHCCCCC
GDVDSVKDNLKPILSNVNIFGVDLYEVGLGERIESYFKEFIEGPGAVRRVLEKYLGCKE
CCHHHHHHHHHHHHCCCCEEEEEHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLTREGIKDVEKWRSRGIKLPNYDVEEISKRTKESPIWLHFGAGNIFRGFIALLQQNLL
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
DKGLIDKGIIAVESYDYEIIEKIYVPYDNLSMLVVMNIDGTLEIEVIGSISDKIIADPSH
HCCCCCCCEEEEECCCHHHHHHHHCCCCCCEEEEEEECCCEEEEEEEECCCCCEEECCCC
SDWERLKNIFSNPSLQIASFTITEKAYNLKDFSGEYIKDVKEDIEEGLDKPKHIISKVTS
HHHHHHHHHHCCCCEEEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
LLYERYKAGKYPLALLSLDNFSGNGERLFNSIKTIAEEWIKKGFVEEGFLNYLTDSTKVS
HHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
FPLSMIDKIVPRPSEEVKKKLEDLGIERMDIIKTSKNTIIAPFVNAEKIHYLVIEDKFPN
CCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHEECCCCEEEEEECCCCEEEEEEEEECCCC
GRPPLEEAGVIFTDKETVEKVERMKVTTCLNPLHTTLAIFGCLLNYSTIADEMKDPCLKK
CCCCHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LVEKVGYDEGLPVVVHPGVLDPEEFLREVIEVRFPNPYMPDTPQRIATDTSQKIAIRFGE
HHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHEEHHHHH
TIKSYKQRSDLKVTDLKYIPLVIAGWLRYLMGLDDEGNPMTLSPDPLLEDLRSHISNIKL
HHHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHCCCCC
GDVDSVKDNLKPILSNVNIFGVDLYEVGLGERIESYFKEFIEGPGAVRRVLEKYLGCKE
CCHHHHHHHHHHHHCCCCEEEEEHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA