Click here to switch to the map view.

The map label for this gene is TrxA4 [H]

Identifier: 20808289

GI number: 20808289

Start: 1824534

End: 1824851

Strand: Reverse

Name: TrxA4 [H]

Synonym: TTE1880

Alternate gene names: 20808289

Gene position: 1824851-1824534 (Counterclockwise)

Preceding gene: 20808290

Following gene: 20808288

Centisome position: 67.85

GC content: 33.33

Gene sequence:

>318_bases
TTGGTGATTGAAGTGAATAAAGACAATTTTGATGAAGTAGTAAAAAAGGAAGAAAAGTTGGTCTTGATTGACTTTTGGGG
ACCAAAGTGCGAACAGTGCCTTGCTTTAATGCCTGAAGTAGAAAAGTTAGAGCAAAAATATGCTGATAAAGTTAAATTTT
GCAAATTAGATGCTTCACAAAACAGGAGATTGTGCATTTCTTTGAAGGTATTAGGACTTCCAACTTTTCAGCTTTACAAA
AATGGCGAAAAAGTGGATGAAATATCAAAAGATGTGACAATAGAGAAGATTGAGGAGATGATAAAAAGGCATATTTAG

Upstream 100 bases:

>100_bases
CTGTTAAGACAAATAGTGACAGCAGCGGCAGATGGGGCGATAGCAGCAGTAGCTGCTGAGAGGTATATTGAAGAATTGGA
GTGTTGAAAGGAGGTGAGAA

Downstream 100 bases:

>100_bases
AGGAGGTGATTTTATGAGGCTGGAAATAGGGAATATTTATATAAAAGATGTGGTGTTTTCTGATGTAACAAAAGTAAAAG
ATGGAGTGCTTTACTTAAAT

Product: Thiol-disulfide isomerase and thioredoxins

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MVIEVNKDNFDEVVKKEEKLVLIDFWGPKCEQCLALMPEVEKLEQKYADKVKFCKLDASQNRRLCISLKVLGLPTFQLYK
NGEKVDEISKDVTIEKIEEMIKRHI

Sequences:

>Translated_105_residues
MVIEVNKDNFDEVVKKEEKLVLIDFWGPKCEQCLALMPEVEKLEQKYADKVKFCKLDASQNRRLCISLKVLGLPTFQLYK
NGEKVDEISKDVTIEKIEEMIKRHI
>Mature_105_residues
MVIEVNKDNFDEVVKKEEKLVLIDFWGPKCEQCLALMPEVEKLEQKYADKVKFCKLDASQNRRLCISLKVLGLPTFQLYK
NGEKVDEISKDVTIEKIEEMIKRHI

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=93, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=8e-12,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 12316; Mature: 12316

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIEVNKDNFDEVVKKEEKLVLIDFWGPKCEQCLALMPEVEKLEQKYADKVKFCKLDASQ
CEEEECCCCHHHHHCCCCCEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHEEECCCCC
NRRLCISLKVLGLPTFQLYKNGEKVDEISKDVTIEKIEEMIKRHI
CCEEEEEEEEECCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MVIEVNKDNFDEVVKKEEKLVLIDFWGPKCEQCLALMPEVEKLEQKYADKVKFCKLDASQ
CEEEECCCCHHHHHCCCCCEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHEEECCCCC
NRRLCISLKVLGLPTFQLYKNGEKVDEISKDVTIEKIEEMIKRHI
CCEEEEEEEEECCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11271425; 9534247 [H]