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The map label for this gene is FtsW2 [H]

Identifier: 20808073

GI number: 20808073

Start: 1595460

End: 1596566

Strand: Reverse

Name: FtsW2 [H]

Synonym: TTE1646

Alternate gene names: 20808073

Gene position: 1596566-1595460 (Counterclockwise)

Preceding gene: 20808074

Following gene: 20808072

Centisome position: 59.36

GC content: 40.74

Gene sequence:

>1107_bases
ATGAAGAAAAAGCCCCCTGTGGATTACGGAATTTTGCTTGTGGTGATGATTTTAGTGGCAATAGGGGTGGTAATGGTTTT
TAGTGCAAGTGCTGCTACTGCCGAGTACATGTACAACGACCCCTATTATTTCCTCAAGAGGCAGCTGGTATGGGCAATAT
TAGGCTTTTTTGCCATGGTTTTTACAATGAATGTAGATTACCTTTGGTTTAAAAGGTGGGCAGGGGCTTTTCTTGTGATT
TCAATAGTACTGCTTGTACTGGTTTTAATCCCAGGAATTGGAGTTGAAAGGTACAATGCTACGAGGTGGATAGGAGTAGG
TAATTTTACTGTTCAGCCCTCTGAAATTGCTAAATATGCTCTTATAATATATCTGGCGAAGTACTTTGACAAACATCCTG
AATATGCAAAGAGCTTAAAAAAAGGAGTAATTCCCGTCTTGGGATTGGCAGGGGTATTTTTTGGGCTGATAATGCTTCAG
CCAAATTTCAGTACTGCAGGCATAATATTTATTGTGTCAGTTGTGATGCTTTTTGTAGCAGGAGCTAAGCTATCCTACAT
GGGAATTCTTCTTGGTACAGGATTAGGGGTTGCAGTTTTAGTTATCTCTTCCTTCAAATATGTGAGGGAAAGAGTTTTAA
CCTTTTTAAATCCGTGGCAGGACATACAGAAGTCTGGCTACCAGATAGTTCAATCACTTTATGCCTTAGGCTCTGGCGGA
CTTTTTGGTGTAGGACTTGGGAACAGTCGTCAGAAGCTCATGTACCTTCCAATGCCTCATAATGACTTTATATTTTCCAT
AATTGGTGAGGAACTTGGGCTTGTGGGTACAGTGACTATTCTTCTCATGTTCTTGTACATAATTTTAAGAGGTTTGAGGG
TAGCAGCTAAAGCGCCAGACATGTTTGGATGCCTTTTAGCTACGGGTATTACCAGTTTAATCGGAATTCAGGCTTTTATT
AATGTAGCAGTTGTTACCTCATCCATGCCGCCCACAGGAGTTTCTCTGCCTTTTATAAGCTATGGAGGTACTTCTACGCT
CATCATGATGGCTGGAGTTGGGATACTTTTGAATATATCGAGACATGCAAATTTAGATAGGAGCTGA

Upstream 100 bases:

>100_bases
CTTCTGTCGCCGGCCTGTGCTAGCTGGGACATGTTTAAAAACTTCGAAGAGAGAGGCAAAGCTTTTAAAAAGGCTGTAAT
GGATTTGAGGAGGTAAAAAG

Downstream 100 bases:

>100_bases
TGACATTTGAGGTATCTGTTTGCAGGAGGAGGCACAGGGGGGCATATTTACCCGGCTGTAGCTATAGCTAAGGAAATTTT
AAAAAATGAACAGGATGCCC

Product: cell division membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKKKPPVDYGILLVVMILVAIGVVMVFSASAATAEYMYNDPYYFLKRQLVWAILGFFAMVFTMNVDYLWFKRWAGAFLVI
SIVLLVLVLIPGIGVERYNATRWIGVGNFTVQPSEIAKYALIIYLAKYFDKHPEYAKSLKKGVIPVLGLAGVFFGLIMLQ
PNFSTAGIIFIVSVVMLFVAGAKLSYMGILLGTGLGVAVLVISSFKYVRERVLTFLNPWQDIQKSGYQIVQSLYALGSGG
LFGVGLGNSRQKLMYLPMPHNDFIFSIIGEELGLVGTVTILLMFLYIILRGLRVAAKAPDMFGCLLATGITSLIGIQAFI
NVAVVTSSMPPTGVSLPFISYGGTSTLIMMAGVGILLNISRHANLDRS

Sequences:

>Translated_368_residues
MKKKPPVDYGILLVVMILVAIGVVMVFSASAATAEYMYNDPYYFLKRQLVWAILGFFAMVFTMNVDYLWFKRWAGAFLVI
SIVLLVLVLIPGIGVERYNATRWIGVGNFTVQPSEIAKYALIIYLAKYFDKHPEYAKSLKKGVIPVLGLAGVFFGLIMLQ
PNFSTAGIIFIVSVVMLFVAGAKLSYMGILLGTGLGVAVLVISSFKYVRERVLTFLNPWQDIQKSGYQIVQSLYALGSGG
LFGVGLGNSRQKLMYLPMPHNDFIFSIIGEELGLVGTVTILLMFLYIILRGLRVAAKAPDMFGCLLATGITSLIGIQAFI
NVAVVTSSMPPTGVSLPFISYGGTSTLIMMAGVGILLNISRHANLDRS
>Mature_368_residues
MKKKPPVDYGILLVVMILVAIGVVMVFSASAATAEYMYNDPYYFLKRQLVWAILGFFAMVFTMNVDYLWFKRWAGAFLVI
SIVLLVLVLIPGIGVERYNATRWIGVGNFTVQPSEIAKYALIIYLAKYFDKHPEYAKSLKKGVIPVLGLAGVFFGLIMLQ
PNFSTAGIIFIVSVVMLFVAGAKLSYMGILLGTGLGVAVLVISSFKYVRERVLTFLNPWQDIQKSGYQIVQSLYALGSGG
LFGVGLGNSRQKLMYLPMPHNDFIFSIIGEELGLVGTVTILLMFLYIILRGLRVAAKAPDMFGCLLATGITSLIGIQAFI
NVAVVTSSMPPTGVSLPFISYGGTSTLIMMAGVGILLNISRHANLDRS

Specific function: May play an essential role not only during sporulation, but also during vegetative growth [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=364, Percent_Identity=39.2857142857143, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1786853, Length=332, Percent_Identity=33.433734939759, Blast_Score=155, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437
- InterPro:   IPR013438 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40223; Mature: 40223

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKPPVDYGILLVVMILVAIGVVMVFSASAATAEYMYNDPYYFLKRQLVWAILGFFAMV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FTMNVDYLWFKRWAGAFLVISIVLLVLVLIPGIGVERYNATRWIGVGNFTVQPSEIAKYA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEECHHHHHHHH
LIIYLAKYFDKHPEYAKSLKKGVIPVLGLAGVFFGLIMLQPNFSTAGIIFIVSVVMLFVA
HHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GAKLSYMGILLGTGLGVAVLVISSFKYVRERVLTFLNPWQDIQKSGYQIVQSLYALGSGG
CCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC
LFGVGLGNSRQKLMYLPMPHNDFIFSIIGEELGLVGTVTILLMFLYIILRGLRVAAKAPD
EEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
MFGCLLATGITSLIGIQAFINVAVVTSSMPPTGVSLPFISYGGTSTLIMMAGVGILLNIS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHCCHHEEEEH
RHANLDRS
HHCCCCCC
>Mature Secondary Structure
MKKKPPVDYGILLVVMILVAIGVVMVFSASAATAEYMYNDPYYFLKRQLVWAILGFFAMV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FTMNVDYLWFKRWAGAFLVISIVLLVLVLIPGIGVERYNATRWIGVGNFTVQPSEIAKYA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEECHHHHHHHH
LIIYLAKYFDKHPEYAKSLKKGVIPVLGLAGVFFGLIMLQPNFSTAGIIFIVSVVMLFVA
HHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GAKLSYMGILLGTGLGVAVLVISSFKYVRERVLTFLNPWQDIQKSGYQIVQSLYALGSGG
CCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC
LFGVGLGNSRQKLMYLPMPHNDFIFSIIGEELGLVGTVTILLMFLYIILRGLRVAAKAPD
EEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
MFGCLLATGITSLIGIQAFINVAVVTSSMPPTGVSLPFISYGGTSTLIMMAGVGILLNIS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHCCHHEEEEH
RHANLDRS
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2115675; 3098901; 9384377; 8436954; 1391053 [H]