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The map label for this gene is murG

Identifier: 20808072

GI number: 20808072

Start: 1594359

End: 1595453

Strand: Reverse

Name: murG

Synonym: TTE1645

Alternate gene names: 20808072

Gene position: 1595453-1594359 (Counterclockwise)

Preceding gene: 20808073

Following gene: 20808071

Centisome position: 59.32

GC content: 38.9

Gene sequence:

>1095_bases
TTGAGGTATCTGTTTGCAGGAGGAGGCACAGGGGGGCATATTTACCCGGCTGTAGCTATAGCTAAGGAAATTTTAAAAAA
TGAACAGGATGCCCAAATACTATTTGTGGGAACAGAAAAGGGCTTGGAGAAAGAACTGGTGCCGCGGGAAGGCTTTGAGC
TAGTCACCATAGAAGTTCAAGGCTTTAAAAGAAAGCTATCTTTCGATACTTTAAAGACTGTGTACAAGGCCTTTACTGGT
TTTAAACAGGCTAATAAAATTTTGAAAGACTTCAAGCCCCATGTGGTGATCGGAACAGGGGGCTATGTATGTGGGCCTGT
TTTGATGGCAGCAGTGATAAAAAGAATACCAACTTTGATCCACGAACAGAATGCTTTTCCAGGACTTACTAATAGATTGC
TTTCGCCTTTTGTAGATATAGTAGCTGTCAGTTTTGAAGATTCTGTTAAGTATTTCAAAAAAGCTAAAAAAGTAGTGGTT
ACAGGTAACCCTATAAGAGAGGAGCTTTTGAGAGTAAAAAAAGAAGAGGGGAGAGAAAAGCTGGGCTTTTCTATGTCCAA
GCCTTTGGTGGTTTCTGTTGGAGGAAGCAGAGGAGCAGAAAAAATCAATTCCACCATGGTGGAATTGTTAAAGATAAAGG
ATAGAAAGTTTCAGGTACTTATAATAACTGGTTCTTCTAACTACGATAAAGTGTTGGAAAAAGTTAAAAAAGAAAATGTG
GTTTTGGACGATTCAGTGAAAATAGTTCCATATAGCCATGAAATGCAGTATGTGTATGCTGCAGCAGATATAATGATTTG
CAGGGCAGGGGCTATAACCCTTTCAGAAATTACAGCAGTGGGAGTTCCATCGATTTTGATTCCATCTCCTTACGTTGCAA
ACAACCATCAGGAGTATAATGCTCGCCTTTTAGAGAGGCAAGGAGCTTTCCATGTGATTTTAGAAAAGGACCTTGATGCC
AAAAAGCTTTATGAAAAGATTGAATATCTTTTAAGTGAGCCTTCCCTCCTTAATGAAATGAGAGAAAAAGCTAAAAGTAT
GAGCAGGACAGATGCATCTTACAAGATATACCAACTCGTTAAAACCATAACTTAA

Upstream 100 bases:

>100_bases
TATAAGCTATGGAGGTACTTCTACGCTCATCATGATGGCTGGAGTTGGGATACTTTTGAATATATCGAGACATGCAAATT
TAGATAGGAGCTGATGACAT

Downstream 100 bases:

>100_bases
TAATATATGTAACACCCCATCTTATCCATGCATAGTATATGGGTGTAAGCGGGAATTTTTTAGGGGGGATAAGATGGGGA
AATTCAAGATAAATGGAGGG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MRYLFAGGGTGGHIYPAVAIAKEILKNEQDAQILFVGTEKGLEKELVPREGFELVTIEVQGFKRKLSFDTLKTVYKAFTG
FKQANKILKDFKPHVVIGTGGYVCGPVLMAAVIKRIPTLIHEQNAFPGLTNRLLSPFVDIVAVSFEDSVKYFKKAKKVVV
TGNPIREELLRVKKEEGREKLGFSMSKPLVVSVGGSRGAEKINSTMVELLKIKDRKFQVLIITGSSNYDKVLEKVKKENV
VLDDSVKIVPYSHEMQYVYAAADIMICRAGAITLSEITAVGVPSILIPSPYVANNHQEYNARLLERQGAFHVILEKDLDA
KKLYEKIEYLLSEPSLLNEMREKAKSMSRTDASYKIYQLVKTIT

Sequences:

>Translated_364_residues
MRYLFAGGGTGGHIYPAVAIAKEILKNEQDAQILFVGTEKGLEKELVPREGFELVTIEVQGFKRKLSFDTLKTVYKAFTG
FKQANKILKDFKPHVVIGTGGYVCGPVLMAAVIKRIPTLIHEQNAFPGLTNRLLSPFVDIVAVSFEDSVKYFKKAKKVVV
TGNPIREELLRVKKEEGREKLGFSMSKPLVVSVGGSRGAEKINSTMVELLKIKDRKFQVLIITGSSNYDKVLEKVKKENV
VLDDSVKIVPYSHEMQYVYAAADIMICRAGAITLSEITAVGVPSILIPSPYVANNHQEYNARLLERQGAFHVILEKDLDA
KKLYEKIEYLLSEPSLLNEMREKAKSMSRTDASYKIYQLVKTIT
>Mature_364_residues
MRYLFAGGGTGGHIYPAVAIAKEILKNEQDAQILFVGTEKGLEKELVPREGFELVTIEVQGFKRKLSFDTLKTVYKAFTG
FKQANKILKDFKPHVVIGTGGYVCGPVLMAAVIKRIPTLIHEQNAFPGLTNRLLSPFVDIVAVSFEDSVKYFKKAKKVVV
TGNPIREELLRVKKEEGREKLGFSMSKPLVVSVGGSRGAEKINSTMVELLKIKDRKFQVLIITGSSNYDKVLEKVKKENV
VLDDSVKIVPYSHEMQYVYAAADIMICRAGAITLSEITAVGVPSILIPSPYVANNHQEYNARLLERQGAFHVILEKDLDA
KKLYEKIEYLLSEPSLLNEMREKAKSMSRTDASYKIYQLVKTIT

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=363, Percent_Identity=30.8539944903581, Blast_Score=182, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_THETN (Q8R9G6)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623243.1
- ProteinModelPortal:   Q8R9G6
- SMR:   Q8R9G6
- GeneID:   996199
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1645
- NMPDR:   fig|273068.3.peg.1627
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   TTEN273068:TTE1645-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40680; Mature: 40680

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLFAGGGTGGHIYPAVAIAKEILKNEQDAQILFVGTEKGLEKELVPREGFELVTIEVQ
CEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHCCCCCCCEEEEEEEE
GFKRKLSFDTLKTVYKAFTGFKQANKILKDFKPHVVIGTGGYVCGPVLMAAVIKRIPTLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
HEQNAFPGLTNRLLSPFVDIVAVSFEDSVKYFKKAKKVVVTGNPIREELLRVKKEEGREK
HCCCCCCHHHHHHHHHHHHHHEECHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHCHHH
LGFSMSKPLVVSVGGSRGAEKINSTMVELLKIKDRKFQVLIITGSSNYDKVLEKVKKENV
HCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHCCE
VLDDSVKIVPYSHEMQYVYAAADIMICRAGAITLSEITAVGVPSILIPSPYVANNHQEYN
EECCCEEEEECCCCCEEEEEHHHHHEEECCCEEHHHHHHHCCCCEECCCCCCCCCCHHHH
ARLLERQGAFHVILEKDLDAKKLYEKIEYLLSEPSLLNEMREKAKSMSRTDASYKIYQLV
HHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
KTIT
HHCC
>Mature Secondary Structure
MRYLFAGGGTGGHIYPAVAIAKEILKNEQDAQILFVGTEKGLEKELVPREGFELVTIEVQ
CEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHCCCCCCCEEEEEEEE
GFKRKLSFDTLKTVYKAFTGFKQANKILKDFKPHVVIGTGGYVCGPVLMAAVIKRIPTLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
HEQNAFPGLTNRLLSPFVDIVAVSFEDSVKYFKKAKKVVVTGNPIREELLRVKKEEGREK
HCCCCCCHHHHHHHHHHHHHHEECHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHCHHH
LGFSMSKPLVVSVGGSRGAEKINSTMVELLKIKDRKFQVLIITGSSNYDKVLEKVKKENV
HCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHCCE
VLDDSVKIVPYSHEMQYVYAAADIMICRAGAITLSEITAVGVPSILIPSPYVANNHQEYN
EECCCEEEEECCCCCEEEEEHHHHHEEECCCEEHHHHHHHCCCCEECCCCCCCCCCHHHH
ARLLERQGAFHVILEKDLDAKKLYEKIEYLLSEPSLLNEMREKAKSMSRTDASYKIYQLV
HHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
KTIT
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336