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The map label for this gene is MurA2

Identifier: 20808071

GI number: 20808071

Start: 1593032

End: 1594285

Strand: Reverse

Name: MurA2

Synonym: TTE1644

Alternate gene names: 20808071

Gene position: 1594285-1593032 (Counterclockwise)

Preceding gene: 20808072

Following gene: 20808070

Centisome position: 59.28

GC content: 40.35

Gene sequence:

>1254_bases
ATGGGGAAATTCAAGATAAATGGAGGGAAGAGGCTTTATGGCGAAGTAGAGGTACATGGGGCTAAAAATTCTATTCTGCC
AATTCTTGCCGCTACTATTTTAAATGAAGGAGTTTCTGTCATTCACAACTGCCCTAGGCTCAAGGATGTAGATTCCATGA
TTGAGATTCTTGAGCACATAGGCTGCAAAGTAAGTTTTAGCGGGAGAGACATCGTAGTAGATGCGAGAGATGTAAAAGAC
AGCGAAATTCCAGACAATTTGATGAGAACCATGCGGTCTTCCATTTTTCTGATGGGAGCCTTAATTGCCCGAAACAAAAA
AGCTTTTATAAGTTTTCCTGGAGGGTGCGATATAGGTCACAGGCCAATAGATTTGCATCTTAAAGGCTTAAAAAAACTGG
GGGTCGAGATTGAAGAGTCTTACGGGTATATAAGATGTAAAGGGGTAAGGGTTAGGGGAAATGAGATTCACTTAGACCTT
CCAAGTGTTGGAGCTACAGAGAACATAATGTTAGCAGCTACATTGGCTGATGGGATAACTGTTATAAGAAATGCGGCTAA
AGAGCCGGAGATAGAAGATTTGCAGAATTTCTTAAACTCCATGGGAGCTAGAATTACTGGAGCAGGAACAAACACTATTG
TGATTGAGGGAGTGAAAAAACTTCATGATACCGAGTACACTATAATTCCGGATAGAATTGTTGCTGGTACTTACCTTTGT
GCTGCGGCAATGACAAGAGGAGAACTGACTGTTGTAAAAGCTTTAAAAGAGCATTTAGAGCCCTTAATTTCTAAACTTAA
AGAAACAGGTTGTGAATTAAAAACAGGAAATGACTATATAAAAATTACCTGCAATAAAAGGCCAAAAGCTGTGGATATGA
TTGTGACCTTGCCTTACCCTGGATTTCCTACGGATTTGCAGCCCCAGATAGTTTCTGTGCTTTCTATTGCTGAAGGCACT
TCAATAGTCACAGAGACTATCTTTGACAATAGATTTAAATACACAGAAGAACTGGTGAGAATGGGAGCTGACATAAAAGT
GGAAGGAAGAGTAGCGGTAATAAGAGGAGTAGACAAAATAACAGGGGCGAAAGTTTTGGCAAAAGACCTAAGGGGAGGAG
TAGCTCTTGTAATAGCTGGATTGGGTGCTGAAGGGACTACTGTTGTAGAAGGAGCAGAACACATAGATAGAGGATACGAA
TCTTTAGAAAAGGCTTTAAAGAGCGTGGGAGCAGATATTGTCAGAATTATGTAA

Upstream 100 bases:

>100_bases
TACCAACTCGTTAAAACCATAACTTAATAATATATGTAACACCCCATCTTATCCATGCATAGTATATGGGTGTAAGCGGG
AATTTTTTAGGGGGGATAAG

Downstream 100 bases:

>100_bases
AACAGCGTCATGCTGTTTTACATATTAGCGGAAAAAGGTACAAGCAGGTGAAAACTATGAACAAAAGAGCCTTTAGAGTA
ATTTTCTTCCTTTTAATTTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MGKFKINGGKRLYGEVEVHGAKNSILPILAATILNEGVSVIHNCPRLKDVDSMIEILEHIGCKVSFSGRDIVVDARDVKD
SEIPDNLMRTMRSSIFLMGALIARNKKAFISFPGGCDIGHRPIDLHLKGLKKLGVEIEESYGYIRCKGVRVRGNEIHLDL
PSVGATENIMLAATLADGITVIRNAAKEPEIEDLQNFLNSMGARITGAGTNTIVIEGVKKLHDTEYTIIPDRIVAGTYLC
AAAMTRGELTVVKALKEHLEPLISKLKETGCELKTGNDYIKITCNKRPKAVDMIVTLPYPGFPTDLQPQIVSVLSIAEGT
SIVTETIFDNRFKYTEELVRMGADIKVEGRVAVIRGVDKITGAKVLAKDLRGGVALVIAGLGAEGTTVVEGAEHIDRGYE
SLEKALKSVGADIVRIM

Sequences:

>Translated_417_residues
MGKFKINGGKRLYGEVEVHGAKNSILPILAATILNEGVSVIHNCPRLKDVDSMIEILEHIGCKVSFSGRDIVVDARDVKD
SEIPDNLMRTMRSSIFLMGALIARNKKAFISFPGGCDIGHRPIDLHLKGLKKLGVEIEESYGYIRCKGVRVRGNEIHLDL
PSVGATENIMLAATLADGITVIRNAAKEPEIEDLQNFLNSMGARITGAGTNTIVIEGVKKLHDTEYTIIPDRIVAGTYLC
AAAMTRGELTVVKALKEHLEPLISKLKETGCELKTGNDYIKITCNKRPKAVDMIVTLPYPGFPTDLQPQIVSVLSIAEGT
SIVTETIFDNRFKYTEELVRMGADIKVEGRVAVIRGVDKITGAKVLAKDLRGGVALVIAGLGAEGTTVVEGAEHIDRGYE
SLEKALKSVGADIVRIM
>Mature_416_residues
GKFKINGGKRLYGEVEVHGAKNSILPILAATILNEGVSVIHNCPRLKDVDSMIEILEHIGCKVSFSGRDIVVDARDVKDS
EIPDNLMRTMRSSIFLMGALIARNKKAFISFPGGCDIGHRPIDLHLKGLKKLGVEIEESYGYIRCKGVRVRGNEIHLDLP
SVGATENIMLAATLADGITVIRNAAKEPEIEDLQNFLNSMGARITGAGTNTIVIEGVKKLHDTEYTIIPDRIVAGTYLCA
AAMTRGELTVVKALKEHLEPLISKLKETGCELKTGNDYIKITCNKRPKAVDMIVTLPYPGFPTDLQPQIVSVLSIAEGTS
IVTETIFDNRFKYTEELVRMGADIKVEGRVAVIRGVDKITGAKVLAKDLRGGVALVIAGLGAEGTTVVEGAEHIDRGYES
LEKALKSVGADIVRIM

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=47.3684210526316, Blast_Score=386, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA2_THETN (Q8R9G7)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623242.1
- ProteinModelPortal:   Q8R9G7
- SMR:   Q8R9G7
- GeneID:   996198
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1644
- NMPDR:   fig|273068.3.peg.1626
- HOGENOM:   HBG482701
- OMA:   TMRSSIF
- ProtClustDB:   PRK09369
- BioCyc:   TTEN273068:TTE1644-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45212; Mature: 45081

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFKINGGKRLYGEVEVHGAKNSILPILAATILNEGVSVIHNCPRLKDVDSMIEILEHI
CCEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHC
GCKVSFSGRDIVVDARDVKDSEIPDNLMRTMRSSIFLMGALIARNKKAFISFPGGCDIGH
CCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
RPIDLHLKGLKKLGVEIEESYGYIRCKGVRVRGNEIHLDLPSVGATENIMLAATLADGIT
CCHHHHHHHHHHCCCEEECCCCEEEEEEEEEECCEEEEECCCCCCCCCEEEEEEHHHHHH
VIRNAAKEPEIEDLQNFLNSMGARITGAGTNTIVIEGVKKLHDTEYTIIPDRIVAGTYLC
HHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEEEEHHHHCCCCEEEECCHHHHHHHHH
AAAMTRGELTVVKALKEHLEPLISKLKETGCELKTGNDYIKITCNKRPKAVDMIVTLPYP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCEEEEEEECCCC
GFPTDLQPQIVSVLSIAEGTSIVTETIFDNRFKYTEELVRMGADIKVEGRVAVIRGVDKI
CCCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEECCCEEEEECCHHH
TGAKVLAKDLRGGVALVIAGLGAEGTTVVEGAEHIDRGYESLEKALKSVGADIVRIM
HHHHHHHHHHCCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure 
GKFKINGGKRLYGEVEVHGAKNSILPILAATILNEGVSVIHNCPRLKDVDSMIEILEHI
CEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHC
GCKVSFSGRDIVVDARDVKDSEIPDNLMRTMRSSIFLMGALIARNKKAFISFPGGCDIGH
CCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
RPIDLHLKGLKKLGVEIEESYGYIRCKGVRVRGNEIHLDLPSVGATENIMLAATLADGIT
CCHHHHHHHHHHCCCEEECCCCEEEEEEEEEECCEEEEECCCCCCCCCEEEEEEHHHHHH
VIRNAAKEPEIEDLQNFLNSMGARITGAGTNTIVIEGVKKLHDTEYTIIPDRIVAGTYLC
HHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEEEEHHHHCCCCEEEECCHHHHHHHHH
AAAMTRGELTVVKALKEHLEPLISKLKETGCELKTGNDYIKITCNKRPKAVDMIVTLPYP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCEEEEEEECCCC
GFPTDLQPQIVSVLSIAEGTSIVTETIFDNRFKYTEELVRMGADIKVEGRVAVIRGVDKI
CCCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEECCCEEEEECCHHH
TGAKVLAKDLRGGVALVIAGLGAEGTTVVEGAEHIDRGYESLEKALKSVGADIVRIM
HHHHHHHHHHCCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336