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The map label for this gene is Dtd [H]

Identifier: 20807651

GI number: 20807651

Start: 1196022

End: 1196489

Strand: Direct

Name: Dtd [H]

Synonym: TTE1196

Alternate gene names: 20807651

Gene position: 1196022-1196489 (Clockwise)

Preceding gene: 20807650

Following gene: 20807652

Centisome position: 44.47

GC content: 39.32

Gene sequence:

>468_bases
GTGCATAGGGGTGATTTTGTGAGAGCTGTTGTACAAAGAGTAACTCGCGGAGAAGTGAGGGTAGACGGCGAAGTTGTGGG
GGCTATAGGAAAAGGGTTTGTGGTTTTAGTGGGAATTGCTGAAGATGACACGGAAGAAGATATAGCTTATATGGCAGACA
AACTGGTGAATTTGAGGGTTTTTGAAGATGAAGAGGGAAAAATGAATTTATCCCTTCTTGATGTGGGAGGAGAAATGCTT
TTGGTTTCTCAATTTACCCTTATGGGAGATGTGAGAAAGGGTAGAAGGCCCAGTTTTACTTCTGCGAAAAAACCTGAGGA
AGCACTTCCTTATTTCAATAAGCTTGTAGAAGAAGTCAGAAAAAAGGGAGTAAAAGTGGAAACTGGTAAATTTCAAGCTA
TGATGAAGGTATTGATTGAAAATGATGGCCCAGTCACTATTTTGATTGACTCAAAAAAATTATTTTAA

Upstream 100 bases:

>100_bases
ATTATAAATCTCACTTTAGAGATTACTTCAAAAGAGCAGTTAGAAAAGGTGATGAACCGCCTTAAGTCTCTAGAAGGAGT
AATGGATGTGTACAGATTAA

Downstream 100 bases:

>100_bases
GTGGAGCTGAGATCTATGGAAGTAAAAAGGTACGTGGTGGGACCTTATGGAGCAAATTTATACGTTGTCTGGGATAGAGA
TACAAGAGAGGGAATAATAA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MHRGDFVRAVVQRVTRGEVRVDGEVVGAIGKGFVVLVGIAEDDTEEDIAYMADKLVNLRVFEDEEGKMNLSLLDVGGEML
LVSQFTLMGDVRKGRRPSFTSAKKPEEALPYFNKLVEEVRKKGVKVETGKFQAMMKVLIENDGPVTILIDSKKLF

Sequences:

>Translated_155_residues
MHRGDFVRAVVQRVTRGEVRVDGEVVGAIGKGFVVLVGIAEDDTEEDIAYMADKLVNLRVFEDEEGKMNLSLLDVGGEML
LVSQFTLMGDVRKGRRPSFTSAKKPEEALPYFNKLVEEVRKKGVKVETGKFQAMMKVLIENDGPVTILIDSKKLF
>Mature_155_residues
MHRGDFVRAVVQRVTRGEVRVDGEVVGAIGKGFVVLVGIAEDDTEEDIAYMADKLVNLRVFEDEEGKMNLSLLDVGGEML
LVSQFTLMGDVRKGRRPSFTSAKKPEEALPYFNKLVEEVRKKGVKVETGKFQAMMKVLIENDGPVTILIDSKKLF

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=47.972972972973, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI1790320, Length=141, Percent_Identity=43.9716312056738, Blast_Score=135, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=48.6666666666667, Blast_Score=129, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=37.8378378378378, Blast_Score=103, Evalue=9e-24,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=44.2176870748299, Blast_Score=116, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 17276; Mature: 17276

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRGDFVRAVVQRVTRGEVRVDGEVVGAIGKGFVVLVGIAEDDTEEDIAYMADKLVNLRV
CCCHHHHHHHHHHHHCCCEEECCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHEEEE
FEDEEGKMNLSLLDVGGEMLLVSQFTLMGDVRKGRRPSFTSAKKPEEALPYFNKLVEEVR
EECCCCCEEEEEEECCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KKGVKVETGKFQAMMKVLIENDGPVTILIDSKKLF
HCCCEEECHHHHHHHHHHHCCCCCEEEEECCCCCC
>Mature Secondary Structure
MHRGDFVRAVVQRVTRGEVRVDGEVVGAIGKGFVVLVGIAEDDTEEDIAYMADKLVNLRV
CCCHHHHHHHHHHHHCCCEEECCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHEEEE
FEDEEGKMNLSLLDVGGEMLLVSQFTLMGDVRKGRRPSFTSAKKPEEALPYFNKLVEEVR
EECCCCCEEEEEEECCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KKGVKVETGKFQAMMKVLIENDGPVTILIDSKKLF
HCCCEEECHHHHHHHHHHHCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]