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The map label for this gene is GloB [C]

Identifier: 20807652

GI number: 20807652

Start: 1196490

End: 1197134

Strand: Direct

Name: GloB [C]

Synonym: TTE1197

Alternate gene names: 20807652

Gene position: 1196490-1197134 (Clockwise)

Preceding gene: 20807651

Following gene: 20807657

Centisome position: 44.49

GC content: 37.36

Gene sequence:

>645_bases
GTGGAGCTGAGATCTATGGAAGTAAAAAGGTACGTGGTGGGACCTTATGGAGCAAATTTATACGTTGTCTGGGATAGAGA
TACAAGAGAGGGAATAATAATAGACCCTGGAGAAGTGTATGACGAGATAAAGAACTATATAAAAGAAAATGGTATAAAGG
TAAAGCACATCCTTCTTACTCACGGGCATTTTGACCATATAGGCGGAGTAGAGGAGATCAGAGCCTTTACAGGAGGAAAA
GTTGCGATTTCAGAAGAAGATGCTCCGATGCTTTTAGACCCTTCTCAGAATTTATCAGAGATGGTCTTTAAAAAGGTGAT
TTGCTCACCAGCTGATATAATTCTAAAAGACAAAGATGTACTAGGCTTCGGAAATTATTATGTAGAAGTTATCTCTACAC
CAGGGCACACCAAAGGAAGTGTATGCTTTAAGATTGGAGATGTATACTTTACAGGGGATACTTTATTTAGGGGTTCTATA
GGAAGACACGATTTTCCTGGAGGAAATTTTGAAACTCTCATGGCTTCAATAAAAGAAAGGCTTTTAACTTTAAAAGATGA
AACAGTGATATACCCGGGCCATGGTGATTTTTCCACAATAGGAAGGGAAAAAAGGCTTAATATGTTTTTGAAAAATTTAG
TATAA

Upstream 100 bases:

>100_bases
AGTAAAAGTGGAAACTGGTAAATTTCAAGCTATGATGAAGGTATTGATTGAAAATGATGGCCCAGTCACTATTTTGATTG
ACTCAAAAAAATTATTTTAA

Downstream 100 bases:

>100_bases
AAAGCAAGAGGAATTTATCCCCTTGCTTTTTATTCATATCTCAATGCTACTATTGGGTCTAGTTTTGCTGCTTTTTGAGC
AGGGTATATTCCAAAGAATA

Product: Zn-dependent hydrolase, including glyoxylases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MELRSMEVKRYVVGPYGANLYVVWDRDTREGIIIDPGEVYDEIKNYIKENGIKVKHILLTHGHFDHIGGVEEIRAFTGGK
VAISEEDAPMLLDPSQNLSEMVFKKVICSPADIILKDKDVLGFGNYYVEVISTPGHTKGSVCFKIGDVYFTGDTLFRGSI
GRHDFPGGNFETLMASIKERLLTLKDETVIYPGHGDFSTIGREKRLNMFLKNLV

Sequences:

>Translated_214_residues
MELRSMEVKRYVVGPYGANLYVVWDRDTREGIIIDPGEVYDEIKNYIKENGIKVKHILLTHGHFDHIGGVEEIRAFTGGK
VAISEEDAPMLLDPSQNLSEMVFKKVICSPADIILKDKDVLGFGNYYVEVISTPGHTKGSVCFKIGDVYFTGDTLFRGSI
GRHDFPGGNFETLMASIKERLLTLKDETVIYPGHGDFSTIGREKRLNMFLKNLV
>Mature_214_residues
MELRSMEVKRYVVGPYGANLYVVWDRDTREGIIIDPGEVYDEIKNYIKENGIKVKHILLTHGHFDHIGGVEEIRAFTGGK
VAISEEDAPMLLDPSQNLSEMVFKKVICSPADIILKDKDVLGFGNYYVEVISTPGHTKGSVCFKIGDVYFTGDTLFRGSI
GRHDFPGGNFETLMASIKERLLTLKDETVIYPGHGDFSTIGREKRLNMFLKNLV

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=194, Percent_Identity=32.4742268041237, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI21703352, Length=183, Percent_Identity=29.5081967213115, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI116642887, Length=183, Percent_Identity=29.5081967213115, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI94538322, Length=183, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI94538320, Length=183, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787158, Length=211, Percent_Identity=35.0710900473934, Blast_Score=134, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17538952, Length=197, Percent_Identity=28.4263959390863, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536925, Length=187, Percent_Identity=30.4812834224599, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320478, Length=206, Percent_Identity=27.1844660194175, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221330176, Length=197, Percent_Identity=30.4568527918782, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 24048; Mature: 24048

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRSMEVKRYVVGPYGANLYVVWDRDTREGIIIDPGEVYDEIKNYIKENGIKVKHILLT
CCCCCCEEEEEEECCCCCEEEEEECCCCCCCEEECCHHHHHHHHHHHHHCCCEEEEEEEE
HGHFDHIGGVEEIRAFTGGKVAISEEDAPMLLDPSQNLSEMVFKKVICSPADIILKDKDV
CCCCHHHCCHHHHHHHCCCEEEECCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEECCCE
LGFGNYYVEVISTPGHTKGSVCFKIGDVYFTGDTLFRGSIGRHDFPGGNFETLMASIKER
EECCCEEEEEECCCCCCCCEEEEEECCEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHH
LLTLKDETVIYPGHGDFSTIGREKRLNMFLKNLV
HEEECCCEEEECCCCCHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure
MELRSMEVKRYVVGPYGANLYVVWDRDTREGIIIDPGEVYDEIKNYIKENGIKVKHILLT
CCCCCCEEEEEEECCCCCEEEEEECCCCCCCEEECCHHHHHHHHHHHHHCCCEEEEEEEE
HGHFDHIGGVEEIRAFTGGKVAISEEDAPMLLDPSQNLSEMVFKKVICSPADIILKDKDV
CCCCHHHCCHHHHHHHCCCEEEECCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEECCCE
LGFGNYYVEVISTPGHTKGSVCFKIGDVYFTGDTLFRGSIGRHDFPGGNFETLMASIKER
EECCCEEEEEECCCCCCCCEEEEEECCEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHH
LLTLKDETVIYPGHGDFSTIGREKRLNMFLKNLV
HEEECCCEEEECCCCCHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]