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The map label for this gene is PncB [H]

Identifier: 20807358

GI number: 20807358

Start: 886533

End: 887567

Strand: Direct

Name: PncB [H]

Synonym: TTE0877

Alternate gene names: 20807358

Gene position: 886533-887567 (Clockwise)

Preceding gene: 20807357

Following gene: 20807359

Centisome position: 32.96

GC content: 42.03

Gene sequence:

>1035_bases
TTGAAAAAGCTAAAATATTTAAAGGACTTAAAAGAAGTAAAAATTGACAAAGATAGGGAATTTTTTTCGGCTACTCACGA
AGAGATAAAGAATGCGTGGACTACTGATGTGTATTTTTTGAGAACACAGGATATTTTAACTTATCTAGGAGTGCAGGATA
AAGTAGTCACAGCAGAGATATTTCCTAGAAAAAAAGGAGTTTTTGCTGGCTTGCCCGAAGTTATGAGCCTTCTCAAAGAC
AAGAACGTAGAGGTGTGGTCTTTAGAAGAAGGAGAGACATTTGAGGCGAAAGAGACAGTCATGAGGATAAGAGGACCCTA
TAGCGAATTTGGGGTGTATGAAACTGCTATTTTGGGCATTCTAGCCAGCTCTTCTGGATGGGCTACTGCTGCAAGAGAGC
TCAAAGAAGTGGCTAAGGACAAACCTGTACTCTGCTTTGGAGCAAGACATGTTCATCCCGCTGTAGCACCTGTTATGGAA
AGAGCTGCCTTGGTGGGAGGAGCGGATGATGCAAGTTGTATACTCGGTGCGAAATTGATGGGCAAAGAGCCAAGAGGAAC
TGTACCTCATGCGGCTTTTTTGATAGTAGGAGATACTTTAGAAGTGGCAAGAGCCTATAGAGATATAACTCCCCCTGATG
AAAAGATTACTATTTTAGTAGACACTTTTAAGGATGAAGTGGAAGAAGCTTTAAGGGTTGCTGAATTTCTCGGAGACAGG
TTGTACGGTGTAAGGCTTGATACTCCCTCTGAAAGGGGAGGAGTTACACCTGATCTAGTCTATGAATTAAGGCAAAGGCT
TAATCAAAAGGGCTTTTCTCATGTAAAGATCATAGTCTCAGGTGGGCTTACGCCTGAGAGAGTCGCACTCCTTGCAGAGA
GCGGGGCAGATGCTTTTGGGGTAGGGAGTTATATTTCTGATGCACAGCCTATTGATATGACTATGGACATAAAAGAAGTT
GAAGGAGTTCCTGTGGCAAAAAGAGGGAGGATTCCGGGAATAATAGAAAACAAGAAGTTAAAAAAGATTAAGTGA

Upstream 100 bases:

>100_bases
TTACCAAATGTATAAGTTTATATATACAAAAAAGTGAAGAAAGCTGGTATAATAGTAATCGTTGAAAGAAAAAAATATTG
GGATAGGGAGGACAAAACAG

Downstream 100 bases:

>100_bases
TTTCCGGAGATGAGTGTTAATGAAAAGATTTCTGGCTTTTGTTTTTATTTTTGCATTTTTACTGACCGGCTGTAAAATTA
ATTCTCCAGATATTACTGCA

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKKLKYLKDLKEVKIDKDREFFSATHEEIKNAWTTDVYFLRTQDILTYLGVQDKVVTAEIFPRKKGVFAGLPEVMSLLKD
KNVEVWSLEEGETFEAKETVMRIRGPYSEFGVYETAILGILASSSGWATAARELKEVAKDKPVLCFGARHVHPAVAPVME
RAALVGGADDASCILGAKLMGKEPRGTVPHAAFLIVGDTLEVARAYRDITPPDEKITILVDTFKDEVEEALRVAEFLGDR
LYGVRLDTPSERGGVTPDLVYELRQRLNQKGFSHVKIIVSGGLTPERVALLAESGADAFGVGSYISDAQPIDMTMDIKEV
EGVPVAKRGRIPGIIENKKLKKIK

Sequences:

>Translated_344_residues
MKKLKYLKDLKEVKIDKDREFFSATHEEIKNAWTTDVYFLRTQDILTYLGVQDKVVTAEIFPRKKGVFAGLPEVMSLLKD
KNVEVWSLEEGETFEAKETVMRIRGPYSEFGVYETAILGILASSSGWATAARELKEVAKDKPVLCFGARHVHPAVAPVME
RAALVGGADDASCILGAKLMGKEPRGTVPHAAFLIVGDTLEVARAYRDITPPDEKITILVDTFKDEVEEALRVAEFLGDR
LYGVRLDTPSERGGVTPDLVYELRQRLNQKGFSHVKIIVSGGLTPERVALLAESGADAFGVGSYISDAQPIDMTMDIKEV
EGVPVAKRGRIPGIIENKKLKKIK
>Mature_344_residues
MKKLKYLKDLKEVKIDKDREFFSATHEEIKNAWTTDVYFLRTQDILTYLGVQDKVVTAEIFPRKKGVFAGLPEVMSLLKD
KNVEVWSLEEGETFEAKETVMRIRGPYSEFGVYETAILGILASSSGWATAARELKEVAKDKPVLCFGARHVHPAVAPVME
RAALVGGADDASCILGAKLMGKEPRGTVPHAAFLIVGDTLEVARAYRDITPPDEKITILVDTFKDEVEEALRVAEFLGDR
LYGVRLDTPSERGGVTPDLVYELRQRLNQKGFSHVKIIVSGGLTPERVALLAESGADAFGVGSYISDAQPIDMTMDIKEV
EGVPVAKRGRIPGIIENKKLKKIK

Specific function: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) [H]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR006405
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 38020; Mature: 38020

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKYLKDLKEVKIDKDREFFSATHEEIKNAWTTDVYFLRTQDILTYLGVQDKVVTAEI
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEEC
FPRKKGVFAGLPEVMSLLKDKNVEVWSLEEGETFEAKETVMRIRGPYSEFGVYETAILGI
CCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LASSSGWATAARELKEVAKDKPVLCFGARHVHPAVAPVMERAALVGGADDASCILGAKLM
HCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GKEPRGTVPHAAFLIVGDTLEVARAYRDITPPDEKITILVDTFKDEVEEALRVAEFLGDR
CCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCC
LYGVRLDTPSERGGVTPDLVYELRQRLNQKGFSHVKIIVSGGLTPERVALLAESGADAFG
EEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCC
VGSYISDAQPIDMTMDIKEVEGVPVAKRGRIPGIIENKKLKKIK
CCHHHCCCCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKLKYLKDLKEVKIDKDREFFSATHEEIKNAWTTDVYFLRTQDILTYLGVQDKVVTAEI
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEEC
FPRKKGVFAGLPEVMSLLKDKNVEVWSLEEGETFEAKETVMRIRGPYSEFGVYETAILGI
CCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LASSSGWATAARELKEVAKDKPVLCFGARHVHPAVAPVMERAALVGGADDASCILGAKLM
HCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GKEPRGTVPHAAFLIVGDTLEVARAYRDITPPDEKITILVDTFKDEVEEALRVAEFLGDR
CCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCC
LYGVRLDTPSERGGVTPDLVYELRQRLNQKGFSHVKIIVSGGLTPERVALLAESGADAFG
EEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCC
VGSYISDAQPIDMTMDIKEVEGVPVAKRGRIPGIIENKKLKKIK
CCHHHCCCCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]