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The map label for this gene is FabH2 [H]

Identifier: 20807058

GI number: 20807058

Start: 564285

End: 565265

Strand: Direct

Name: FabH2 [H]

Synonym: TTE0557

Alternate gene names: 20807058

Gene position: 564285-565265 (Clockwise)

Preceding gene: 20807057

Following gene: 20807059

Centisome position: 20.98

GC content: 36.9

Gene sequence:

>981_bases
ATGAGAAGAGCGCGAATCATAGGAGTGGGAAGTTATCACCCAAAAAATTTGATAACAAATGAAGAACTGTCAAAAAGAAT
AGGTGAGCCAATAAGCATAAATTTTGAAAAAAAGGTTGGAATACTTCAAAGATATATAACTGGACCGGATGAAAGTACTG
CAGACCTTGCATATGAAGCAGCTAAAAGAGCCCTTGAAATGGCAAATGTATCACCGAAGGATATTGATTTGATAATTTTA
GCCACAGATACTCCTGAATATATTACTCCACCAACTTCTGCAATTGTACAGGGCAGGCTTGGAGCGATAAATGCTGGATT
TTTTGATATAAATGCTTCTTGCGCTGGATTTGCAGGTTCACTTGCAGTTGCATCCAAAATGATTATGGCAGATGACTCGT
TAAATAAAGTCTTAGTTATTGGTGCATATAACATGAGTAAATTTGTTGACTATAATACACCAGGACTTTCTGCTATATTT
GCAGATGGTGGCGGAGCGGTTGTACTTACTTCAACAGAAGAAGATGCTGGATTTTTAGCATCTAAATTTATAGGTGATGG
TACACAGTATGATTTTTTGGGTATATATGATGGTGGGGCGAAAAATCCGTTTAGAAAGGGCAATCCTAAAGATCAGCTTT
TGACTTCTCTAAAACCCCTTCCCCCAGATAGGAATCTTAAAATGTGGCCTCCTCTTGTAAAGGAAGTTGTGGAAAAAGCA
GGTTATAAAGTTAAAGACATTGATCATATTTTCTTTACTCAGATAAATAAGTCAGTGATATTAGAAGTTATGGACACATT
GGGATTAGATCGATCAAAGACAACTACTATTATGGAAAAATATGGTTATACAGGCTCGGCATGTCTTCCCATGGCTTTAG
ATGATGCAGTAAAAAATAATAGGATAAAGAAGGGAGACCTCATTGTATTCGTAGGTTCCGGAGTAGGTTTCTCTATGGCT
GCCTCAGCTTTTATATATTAA

Upstream 100 bases:

>100_bases
GTTATTGAAAATGCGGCTCATAGTGTGTTTATTGATAATGAAGAACAAACATTAAAGGTTATGCTAGACTTTATTGAGAA
ATAGGGGAGGAGATAAATAT

Downstream 100 bases:

>100_bases
CTGTGCTTATCTTGGTGAATAATATGGGGTGATAAAATGACCCTTATTGAGGCGTTTAAAAAAATAGCACCATTTATTAA
TACAATGACCACAGAGGATT

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MRRARIIGVGSYHPKNLITNEELSKRIGEPISINFEKKVGILQRYITGPDESTADLAYEAAKRALEMANVSPKDIDLIIL
ATDTPEYITPPTSAIVQGRLGAINAGFFDINASCAGFAGSLAVASKMIMADDSLNKVLVIGAYNMSKFVDYNTPGLSAIF
ADGGGAVVLTSTEEDAGFLASKFIGDGTQYDFLGIYDGGAKNPFRKGNPKDQLLTSLKPLPPDRNLKMWPPLVKEVVEKA
GYKVKDIDHIFFTQINKSVILEVMDTLGLDRSKTTTIMEKYGYTGSACLPMALDDAVKNNRIKKGDLIVFVGSGVGFSMA
ASAFIY

Sequences:

>Translated_326_residues
MRRARIIGVGSYHPKNLITNEELSKRIGEPISINFEKKVGILQRYITGPDESTADLAYEAAKRALEMANVSPKDIDLIIL
ATDTPEYITPPTSAIVQGRLGAINAGFFDINASCAGFAGSLAVASKMIMADDSLNKVLVIGAYNMSKFVDYNTPGLSAIF
ADGGGAVVLTSTEEDAGFLASKFIGDGTQYDFLGIYDGGAKNPFRKGNPKDQLLTSLKPLPPDRNLKMWPPLVKEVVEKA
GYKVKDIDHIFFTQINKSVILEVMDTLGLDRSKTTTIMEKYGYTGSACLPMALDDAVKNNRIKKGDLIVFVGSGVGFSMA
ASAFIY
>Mature_326_residues
MRRARIIGVGSYHPKNLITNEELSKRIGEPISINFEKKVGILQRYITGPDESTADLAYEAAKRALEMANVSPKDIDLIIL
ATDTPEYITPPTSAIVQGRLGAINAGFFDINASCAGFAGSLAVASKMIMADDSLNKVLVIGAYNMSKFVDYNTPGLSAIF
ADGGGAVVLTSTEEDAGFLASKFIGDGTQYDFLGIYDGGAKNPFRKGNPKDQLLTSLKPLPPDRNLKMWPPLVKEVVEKA
GYKVKDIDHIFFTQINKSVILEVMDTLGLDRSKTTTIMEKYGYTGSACLPMALDDAVKNNRIKKGDLIVFVGSGVGFSMA
ASAFIY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=319, Percent_Identity=28.8401253918495, Blast_Score=142, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 35216; Mature: 35216

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRARIIGVGSYHPKNLITNEELSKRIGEPISINFEKKVGILQRYITGPDESTADLAYEA
CCCEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHH
AKRALEMANVSPKDIDLIILATDTPEYITPPTSAIVQGRLGAINAGFFDINASCAGFAGS
HHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCCCEEECCEEEECCCCCCCHHH
LAVASKMIMADDSLNKVLVIGAYNMSKFVDYNTPGLSAIFADGGGAVVLTSTEEDAGFLA
HHHHHHHHEECCCCCEEEEEEECCHHHHEECCCCCCEEEEECCCCEEEEEECCCCHHHHH
SKFIGDGTQYDFLGIYDGGAKNPFRKGNPKDQLLTSLKPLPPDRNLKMWPPLVKEVVEKA
HHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
GYKVKDIDHIFFTQINKSVILEVMDTLGLDRSKTTTIMEKYGYTGSACLPMALDDAVKNN
CCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCC
RIKKGDLIVFVGSGVGFSMAASAFIY
CCCCCCEEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure
MRRARIIGVGSYHPKNLITNEELSKRIGEPISINFEKKVGILQRYITGPDESTADLAYEA
CCCEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHH
AKRALEMANVSPKDIDLIILATDTPEYITPPTSAIVQGRLGAINAGFFDINASCAGFAGS
HHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCCCEEECCEEEECCCCCCCHHH
LAVASKMIMADDSLNKVLVIGAYNMSKFVDYNTPGLSAIFADGGGAVVLTSTEEDAGFLA
HHHHHHHHEECCCCCEEEEEEECCHHHHEECCCCCCEEEEECCCCEEEEEECCCCHHHHH
SKFIGDGTQYDFLGIYDGGAKNPFRKGNPKDQLLTSLKPLPPDRNLKMWPPLVKEVVEKA
HHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
GYKVKDIDHIFFTQINKSVILEVMDTLGLDRSKTTTIMEKYGYTGSACLPMALDDAVKNN
CCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCC
RIKKGDLIVFVGSGVGFSMAASAFIY
CCCCCCEEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA