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The map label for this gene is MhpC2 [H]

Identifier: 20807057

GI number: 20807057

Start: 563372

End: 564268

Strand: Direct

Name: MhpC2 [H]

Synonym: TTE0556

Alternate gene names: 20807057

Gene position: 563372-564268 (Clockwise)

Preceding gene: 20807056

Following gene: 20807058

Centisome position: 20.95

GC content: 33.11

Gene sequence:

>897_bases
ATGTGTAGAGTAATATATAAAAAAATTGCTTTACCAAATGGAGAGGAAATTGGTTACAGAGAAAGAGAAGGAGGAAAAGA
CGCAATAATTTTTGTTCATGGTAATTTAGTTTCATCAAAATATTGGGAAAGATTTATGCAAAGATTTCCTGAAAATTTTA
AACTTTATGCAGTAGATTTAAGAGGAGCAGGAATCTCTTCATATAACAAGCCTATTGAAACAATGAGGGATTTTTCTGAA
GATATATGGCTTTTTTCACAAGAAATGAATATCAAAGAGTTTATTCTTGTAGGGTGGTCGATGGGCGGAGTAATTTCTAT
GCAACTAGCGGCTGACCACCCTGATGCAGTAAAAAAATTGATCCTTGTAAGTTCACCATCTTGCAAAGGTATACCATTTA
CAAAAAAAGATGAAGAAGGTAAAGTGATACCGGGTGAATATTGGAAAACAAAAGAAGAAGTGTTTAATGATAAAGTACAA
GTTTTGCCGATAGTTTATGCATTGAGATCGGGAAACAGAGAAATAATGAAAAATATTTGGGATTCTGCTGTGTTTAACTA
TAAAAAGCCTGAAGAAAACTATTACAAAGAGCTCATAGAAGATATTTTTACAGTAAGAAATTATCCTGATTGTGCGTGGG
CGACGCAGATTTTTAATATATCACATTTTCATAATGGTGTAGTCATGGGCACAGGAGAAGTAGATAAACTAACAATGCCT
GTATTGTTATTATGGGGAGAATATGATGTAATCGTAAAAAAAGAGTATAGCGAAGAAACAGCAAAAGAAATCGGGGAGAA
TGCCCATGTTGTAGTTATTGAAAATGCGGCTCATAGTGTGTTTATTGATAATGAAGAACAAACATTAAAGGTTATGCTAG
ACTTTATTGAGAAATAG

Upstream 100 bases:

>100_bases
TAGCAAAAGTAAATTATATTTCAAGCAGTTTATTTCCTCGGAAACAAATTAAAATATTATATTACGTTGTAGATGTTAAA
AATAAAGGGGGTTAAAATTT

Downstream 100 bases:

>100_bases
GGGAGGAGATAAATATATGAGAAGAGCGCGAATCATAGGAGTGGGAAGTTATCACCCAAAAAATTTGATAACAAATGAAG
AACTGTCAAAAAGAATAGGT

Product: alpha/beta superfamily hydrolase/acyltransferase

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MCRVIYKKIALPNGEEIGYREREGGKDAIIFVHGNLVSSKYWERFMQRFPENFKLYAVDLRGAGISSYNKPIETMRDFSE
DIWLFSQEMNIKEFILVGWSMGGVISMQLAADHPDAVKKLILVSSPSCKGIPFTKKDEEGKVIPGEYWKTKEEVFNDKVQ
VLPIVYALRSGNREIMKNIWDSAVFNYKKPEENYYKELIEDIFTVRNYPDCAWATQIFNISHFHNGVVMGTGEVDKLTMP
VLLLWGEYDVIVKKEYSEETAKEIGENAHVVVIENAAHSVFIDNEEQTLKVMLDFIEK

Sequences:

>Translated_298_residues
MCRVIYKKIALPNGEEIGYREREGGKDAIIFVHGNLVSSKYWERFMQRFPENFKLYAVDLRGAGISSYNKPIETMRDFSE
DIWLFSQEMNIKEFILVGWSMGGVISMQLAADHPDAVKKLILVSSPSCKGIPFTKKDEEGKVIPGEYWKTKEEVFNDKVQ
VLPIVYALRSGNREIMKNIWDSAVFNYKKPEENYYKELIEDIFTVRNYPDCAWATQIFNISHFHNGVVMGTGEVDKLTMP
VLLLWGEYDVIVKKEYSEETAKEIGENAHVVVIENAAHSVFIDNEEQTLKVMLDFIEK
>Mature_298_residues
MCRVIYKKIALPNGEEIGYREREGGKDAIIFVHGNLVSSKYWERFMQRFPENFKLYAVDLRGAGISSYNKPIETMRDFSE
DIWLFSQEMNIKEFILVGWSMGGVISMQLAADHPDAVKKLILVSSPSCKGIPFTKKDEEGKVIPGEYWKTKEEVFNDKVQ
VLPIVYALRSGNREIMKNIWDSAVFNYKKPEENYYKELIEDIFTVRNYPDCAWATQIFNISHFHNGVVMGTGEVDKLTMP
VLLLWGEYDVIVKKEYSEETAKEIGENAHVVVIENAAHSVFIDNEEQTLKVMLDFIEK

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

Organism=Homo sapiens, GI189027141, Length=287, Percent_Identity=23.6933797909408, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 34391; Mature: 34391

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRVIYKKIALPNGEEIGYREREGGKDAIIFVHGNLVSSKYWERFMQRFPENFKLYAVDL
CCHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEE
RGAGISSYNKPIETMRDFSEDIWLFSQEMNIKEFILVGWSMGGVISMQLAADHPDAVKKL
CCCCCCCCCCHHHHHHHHHHHHEEEECCCCCEEEEEEEECCCCEEEEEEECCCHHHHHHE
ILVSSPSCKGIPFTKKDEEGKVIPGEYWKTKEEVFNDKVQVLPIVYALRSGNREIMKNIW
EEEECCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
DSAVFNYKKPEENYYKELIEDIFTVRNYPDCAWATQIFNISHFHNGVVMGTGEVDKLTMP
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHEEE
VLLLWGEYDVIVKKEYSEETAKEIGENAHVVVIENAAHSVFIDNEEQTLKVMLDFIEK
EEEEECCEEEEEECCHHHHHHHHHCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MCRVIYKKIALPNGEEIGYREREGGKDAIIFVHGNLVSSKYWERFMQRFPENFKLYAVDL
CCHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEE
RGAGISSYNKPIETMRDFSEDIWLFSQEMNIKEFILVGWSMGGVISMQLAADHPDAVKKL
CCCCCCCCCCHHHHHHHHHHHHEEEECCCCCEEEEEEEECCCCEEEEEEECCCHHHHHHE
ILVSSPSCKGIPFTKKDEEGKVIPGEYWKTKEEVFNDKVQVLPIVYALRSGNREIMKNIW
EEEECCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
DSAVFNYKKPEENYYKELIEDIFTVRNYPDCAWATQIFNISHFHNGVVMGTGEVDKLTMP
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHEEE
VLLLWGEYDVIVKKEYSEETAKEIGENAHVVVIENAAHSVFIDNEEQTLKVMLDFIEK
EEEEECCEEEEEECCHHHHHHHHHCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA