BacMap

Definition	Thermoanaerobacter tengcongensis MB4, complete genome.
Accession	NC_003869
Length	2,689,445

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The map label for this gene is CaiD [H]

Identifier: 20807045

GI number: 20807045

Start: 550572

End: 551354

Strand: Direct

Name: CaiD [H]

Synonym: TTE0544

Alternate gene names: 20807045

Gene position: 550572-551354 (Clockwise)

Preceding gene: 20807044

Following gene: 20807046

Centisome position: 20.47

GC content: 39.08

Gene sequence:

>783_bases
GTGGAATATAAAAACATAGAAGTGAAAATTGAAAAGGGGATTGCCACAATCACAATTAACAGGCCAAAGGCTTTAAATGC
ATTAAACACAGAGACTCTTGAAGAATTAGAAAATGTTTTAGAAGTTTTGCAAAATGACGATGGGGTAAAAGTTATAGTTA
TAACTGGTGCAGGAGAAAAGGCATTTGTGGCAGGAGCAGATATTTCTGAAATGAAGGACATGAGCGTATTTGAGGCGAAA
AAGTTTGCTGAGTTAGGTCAGAAGGTATTTAGAAAGATTGAACTTGTGAAGAAGCCAGTCATTGCTGCTGTGAATGGATA
CGCTCTTGGAGGAGGATGTGAACTTGCTTTGGCTTGCGATATAAGGATTGCAAGTCGTAATGCAAAATTTGGTCAGCCAG
AAGTAGGACTTGGAATTATACCGGGATTTGGTGGTACGCAGAGGCTACCTCGAATTGTAGGTGTTTCAAAAGCGAAAGAA
CTCATATACACTGGAGATATGATAGATGCAGAGGAGGCTTTGAGAATAGGCCTTATTTCAAAAGTAGTAGAACAAGATAA
ACTTTTAGAGGAAGCTTATGGTATTGCAAAAAAGATAATGTCAAAAGGGCTTGTGGCAGTATCACTGGCTAAAGAAGCTA
TAAACAAAAGCCTCGAAGTTGATATCGATTCAGGCATGGAATATGAGGCCAATGCTTTTGCCATGTGTTTTGGTACACAG
GATCAAAAAGAGGGCATGGCAGCTTTTTTAGAGAAGAGAGCTCCTAAATTTGAAGGAAGATGA

Upstream 100 bases:

>100_bases
ACAGTGAAAGTAGATGGATGAAATGTCCATCTACTTTTTATTTTGGCATGATTTTTGCATAAAATATTAAAAGCGAAAAC
TCAAAAGGAGGGTGACTTTG

Downstream 100 bases:

>100_bases
GGGGAATGCCCCTCACTGTACCCTAGAATGTTAAAAAAATATCAAAAAGGAGGAGTGTATATGGATTTTTCTTTTACCAG
AGAACAAGAGATGGTGAGAA

Product: 3-hydroxybutyryl-CoA dehydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MEYKNIEVKIEKGIATITINRPKALNALNTETLEELENVLEVLQNDDGVKVIVITGAGEKAFVAGADISEMKDMSVFEAK
KFAELGQKVFRKIELVKKPVIAAVNGYALGGGCELALACDIRIASRNAKFGQPEVGLGIIPGFGGTQRLPRIVGVSKAKE
LIYTGDMIDAEEALRIGLISKVVEQDKLLEEAYGIAKKIMSKGLVAVSLAKEAINKSLEVDIDSGMEYEANAFAMCFGTQ
DQKEGMAAFLEKRAPKFEGR

Sequences:

>Translated_260_residues
MEYKNIEVKIEKGIATITINRPKALNALNTETLEELENVLEVLQNDDGVKVIVITGAGEKAFVAGADISEMKDMSVFEAK
KFAELGQKVFRKIELVKKPVIAAVNGYALGGGCELALACDIRIASRNAKFGQPEVGLGIIPGFGGTQRLPRIVGVSKAKE
LIYTGDMIDAEEALRIGLISKVVEQDKLLEEAYGIAKKIMSKGLVAVSLAKEAINKSLEVDIDSGMEYEANAFAMCFGTQ
DQKEGMAAFLEKRAPKFEGR
>Mature_260_residues
MEYKNIEVKIEKGIATITINRPKALNALNTETLEELENVLEVLQNDDGVKVIVITGAGEKAFVAGADISEMKDMSVFEAK
KFAELGQKVFRKIELVKKPVIAAVNGYALGGGCELALACDIRIASRNAKFGQPEVGLGIIPGFGGTQRLPRIVGVSKAKE
LIYTGDMIDAEEALRIGLISKVVEQDKLLEEAYGIAKKIMSKGLVAVSLAKEAINKSLEVDIDSGMEYEANAFAMCFGTQ
DQKEGMAAFLEKRAPKFEGR

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=245, Percent_Identity=47.7551020408163, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI4502327, Length=252, Percent_Identity=42.4603174603175, Blast_Score=168, Evalue=4e-42,
Organism=Homo sapiens, GI150378541, Length=254, Percent_Identity=35.8267716535433, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI31542718, Length=253, Percent_Identity=35.1778656126482, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI20127408, Length=239, Percent_Identity=33.8912133891213, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI68989263, Length=214, Percent_Identity=39.2523364485981, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=32.3308270676692, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI221136756, Length=260, Percent_Identity=26.1538461538462, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI221136753, Length=260, Percent_Identity=26.1538461538462, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI221307494, Length=260, Percent_Identity=26.1538461538462, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI37594469, Length=250, Percent_Identity=31.2, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI37594471, Length=250, Percent_Identity=31.2, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI157694516, Length=247, Percent_Identity=28.3400809716599, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI213417737, Length=247, Percent_Identity=28.3400809716599, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI261878539, Length=114, Percent_Identity=44.7368421052632, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI62530384, Length=242, Percent_Identity=25.6198347107438, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI260274832, Length=218, Percent_Identity=30.7339449541284, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI45643119, Length=256, Percent_Identity=27.734375, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI260275230, Length=256, Percent_Identity=27.734375, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI4757968, Length=262, Percent_Identity=24.4274809160305, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI49355787, Length=262, Percent_Identity=24.4274809160305, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI25453481, Length=260, Percent_Identity=24.6153846153846, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI51538573, Length=260, Percent_Identity=24.6153846153846, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI157694520, Length=222, Percent_Identity=27.9279279279279, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI116235487, Length=256, Percent_Identity=25, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4757966, Length=249, Percent_Identity=24.8995983935743, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI51538581, Length=249, Percent_Identity=24.8995983935743, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI295842266, Length=240, Percent_Identity=22.9166666666667, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1787659, Length=255, Percent_Identity=43.5294117647059, Blast_Score=210, Evalue=6e-56,
Organism=Escherichia coli, GI221142681, Length=251, Percent_Identity=38.2470119521912, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1790281, Length=200, Percent_Identity=38.5, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1787660, Length=267, Percent_Identity=36.3295880149813, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1788597, Length=257, Percent_Identity=35.7976653696498, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788682, Length=189, Percent_Identity=41.7989417989418, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87082183, Length=262, Percent_Identity=30.1526717557252, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17554946, Length=258, Percent_Identity=46.8992248062016, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI25145438, Length=250, Percent_Identity=47.6, Blast_Score=211, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17540714, Length=224, Percent_Identity=42.8571428571429, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17558304, Length=235, Percent_Identity=37.4468085106383, Blast_Score=135, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17534483, Length=258, Percent_Identity=30.2325581395349, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI25144276, Length=229, Percent_Identity=37.117903930131, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17508953, Length=229, Percent_Identity=37.117903930131, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17508951, Length=229, Percent_Identity=37.117903930131, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17536985, Length=245, Percent_Identity=31.0204081632653, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17560910, Length=251, Percent_Identity=33.4661354581673, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17540306, Length=241, Percent_Identity=30.7053941908714, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144160, Length=180, Percent_Identity=31.1111111111111, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25144157, Length=180, Percent_Identity=31.1111111111111, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17549921, Length=208, Percent_Identity=28.8461538461538, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI25141363, Length=206, Percent_Identity=28.1553398058252, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=272, Percent_Identity=28.6764705882353, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320241, Length=185, Percent_Identity=30.2702702702703, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20129971, Length=258, Percent_Identity=49.6124031007752, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24653477, Length=258, Percent_Identity=49.6124031007752, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24653139, Length=252, Percent_Identity=42.8571428571429, Blast_Score=196, Evalue=1e-50,
Organism=Drosophila melanogaster, GI19922422, Length=260, Percent_Identity=31.5384615384615, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI19920382, Length=265, Percent_Identity=30.9433962264151, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24583077, Length=185, Percent_Identity=38.3783783783784, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24583079, Length=185, Percent_Identity=38.3783783783784, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19921000, Length=185, Percent_Identity=38.3783783783784, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21357171, Length=201, Percent_Identity=34.3283582089552, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24654903, Length=190, Percent_Identity=30, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24650670, Length=197, Percent_Identity=32.48730964467, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19921018, Length=181, Percent_Identity=33.1491712707182, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24583165, Length=247, Percent_Identity=25.9109311740891, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571730, Length=139, Percent_Identity=34.5323741007194, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28571729, Length=139, Percent_Identity=34.5323741007194, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45550169, Length=253, Percent_Identity=24.1106719367589, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28131; Mature: 28131

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYKNIEVKIEKGIATITINRPKALNALNTETLEELENVLEVLQNDDGVKVIVITGAGEK
CCCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCE
AFVAGADISEMKDMSVFEAKKFAELGQKVFRKIELVKKPVIAAVNGYALGGGCELALACD
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCEEECCCCEEEEEEE
IRIASRNAKFGQPEVGLGIIPGFGGTQRLPRIVGVSKAKELIYTGDMIDAEEALRIGLIS
EEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
KVVEQDKLLEEAYGIAKKIMSKGLVAVSLAKEAINKSLEVDIDSGMEYEANAFAMCFGTQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCC
DQKEGMAAFLEKRAPKFEGR
CHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEYKNIEVKIEKGIATITINRPKALNALNTETLEELENVLEVLQNDDGVKVIVITGAGEK
CCCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCE
AFVAGADISEMKDMSVFEAKKFAELGQKVFRKIELVKKPVIAAVNGYALGGGCELALACD
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCEEECCCCEEEEEEE
IRIASRNAKFGQPEVGLGIIPGFGGTQRLPRIVGVSKAKELIYTGDMIDAEEALRIGLIS
EEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
KVVEQDKLLEEAYGIAKKIMSKGLVAVSLAKEAINKSLEVDIDSGMEYEANAFAMCFGTQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCC
DQKEGMAAFLEKRAPKFEGR
CHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]