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The map label for this gene is HypB [H]

Identifier: 20806659

GI number: 20806659

Start: 130313

End: 130969

Strand: Direct

Name: HypB [H]

Synonym: TTE0130

Alternate gene names: 20806659

Gene position: 130313-130969 (Clockwise)

Preceding gene: 20806658

Following gene: 20806660

Centisome position: 4.85

GC content: 39.73

Gene sequence:

>657_bases
ATGGAGGAAATTGTAATAATAAGAGATGTTTTAGAGACGAATAAAAATATAGCCTCCGAAAACAAGGCTATTAAGGATGA
GAGAAATATTTTGATGGTGAATTTGATAGGTTCGCCGGGTGCAGGCAAGACCAGCTTTATAATAAAAGCGATAGAGCACA
TGAAGGTACCCTGTGCGGTAATTGAGGGAGATGTTACATCAGACATTGACGCAAGAAAAATGGCTGAGAGAAATATCCCG
GTTGTGCAGATAAACACAGGAGGGGCTTGTCACTTAAACGCAGCATCAGTCAATAAAGCCCTTCAGGCTTTAAACTTTGA
CAATGGCATAGTCTTTATTGAAAATGTTGGGAACTTGATATGCCCCTCTGCTTTTGAATTAGGCGAAGACTTTAAACTAG
CTATGGCAAATGTTCCGGAAGGGGATGACAAGCCATACAAATATCCTGCGCTTTTTAGCAAGGCAAAGGCAGTTGTACTG
AATAAAATTGACATGCTTCCCTATTTTGAGTTTGACAGAAAGTTTTTCTATGATGGTGTTAGAGCATTAAATCAAGAAGC
GCCAATTTTTGAAGTCTCTGCAAGAACAGGGGAAGGATTTGGTGAATTTGCAAGATGGTTAGAGGAAGAGTACCACAAAT
TCAGGCAAGGCAAATAA

Upstream 100 bases:

>100_bases
TCCAATTTCACTTTTAAGTGTCCTGTATGCGGAGGGCAGGGAGTACTAATTGATAAGAGGGGGAAAGAATTTTATATTGA
GAGCATAGAGGTGGAATAGC

Downstream 100 bases:

>100_bases
ATATCTTTGGAATTGTACAGGGCGTGGGTTTTCGCCCTTTTGTCTTTAATATTGCCCAGAAATACAATTTAAAAGGAATA
GTTTACAACAACTCCTCAGG

Product: Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MEEIVIIRDVLETNKNIASENKAIKDERNILMVNLIGSPGAGKTSFIIKAIEHMKVPCAVIEGDVTSDIDARKMAERNIP
VVQINTGGACHLNAASVNKALQALNFDNGIVFIENVGNLICPSAFELGEDFKLAMANVPEGDDKPYKYPALFSKAKAVVL
NKIDMLPYFEFDRKFFYDGVRALNQEAPIFEVSARTGEGFGEFARWLEEEYHKFRQGK

Sequences:

>Translated_218_residues
MEEIVIIRDVLETNKNIASENKAIKDERNILMVNLIGSPGAGKTSFIIKAIEHMKVPCAVIEGDVTSDIDARKMAERNIP
VVQINTGGACHLNAASVNKALQALNFDNGIVFIENVGNLICPSAFELGEDFKLAMANVPEGDDKPYKYPALFSKAKAVVL
NKIDMLPYFEFDRKFFYDGVRALNQEAPIFEVSARTGEGFGEFARWLEEEYHKFRQGK
>Mature_218_residues
MEEIVIIRDVLETNKNIASENKAIKDERNILMVNLIGSPGAGKTSFIIKAIEHMKVPCAVIEGDVTSDIDARKMAERNIP
VVQINTGGACHLNAASVNKALQALNFDNGIVFIENVGNLICPSAFELGEDFKLAMANVPEGDDKPYKYPALFSKAKAVVL
NKIDMLPYFEFDRKFFYDGVRALNQEAPIFEVSARTGEGFGEFARWLEEEYHKFRQGK

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=205, Percent_Identity=44.8780487804878, Blast_Score=187, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 24291; Mature: 24291

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEIVIIRDVLETNKNIASENKAIKDERNILMVNLIGSPGAGKTSFIIKAIEHMKVPCAV
CCCEEEEHHHHHCCCCHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEE
IEGDVTSDIDARKMAERNIPVVQINTGGACHLNAASVNKALQALNFDNGIVFIENVGNLI
EECCCCCCCHHHHHHHCCCCEEEEECCCEEEECHHHHHHHHHHHCCCCCEEEEECCCCCC
CPSAFELGEDFKLAMANVPEGDDKPYKYPALFSKAKAVVLNKIDMLPYFEFDRKFFYDGV
CCCHHHCCCCCEEEECCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RALNQEAPIFEVSARTGEGFGEFARWLEEEYHKFRQGK
HHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEEIVIIRDVLETNKNIASENKAIKDERNILMVNLIGSPGAGKTSFIIKAIEHMKVPCAV
CCCEEEEHHHHHCCCCHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEE
IEGDVTSDIDARKMAERNIPVVQINTGGACHLNAASVNKALQALNFDNGIVFIENVGNLI
EECCCCCCCHHHHHHHCCCCEEEEECCCEEEECHHHHHHHHHHHCCCCCEEEEECCCCCC
CPSAFELGEDFKLAMANVPEGDDKPYKYPALFSKAKAVVLNKIDMLPYFEFDRKFFYDGV
CCCHHHCCCCCEEEECCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RALNQEAPIFEVSARTGEGFGEFARWLEEEYHKFRQGK
HHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]