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The map label for this gene is 20095041

Identifier: 20095041

GI number: 20095041

Start: 1614640

End: 1615353

Strand: Direct

Name: 20095041

Synonym: MK1605

Alternate gene names: NA

Gene position: 1614640-1615353 (Clockwise)

Preceding gene: 20095040

Following gene: 20095059

Centisome position: 95.26

GC content: 58.96

Gene sequence:

>714_bases
ATGACCTCGACGGAAAAGGCCAGGATCCGAAGGATGGTGTGGGAAGAGCTCGAGGAGTCCGGCGAGGCCGCGCCCCCGTT
CCCCGTCGAGGGCAGGATCCCGAACTTCAAGGGCGCCTTAGTAGCGGCTCGACGGCTCACTTCGACGCCCGAATACGAGG
AAGCCGAAGTGGTGAAGGTAAATCCGGACTCACCCCAACGACCTGTACGTGAACGAGCGCTTCGCGACGGTAAGATCCTG
ATAATGCCGACACCGAGGCTCAAACGTGGCTTCCTCGTCGTGAAGAACCCTAAAGATCCTCGACGTGCCTCAACGATTAG
GGGAGCTTTCCAGGAAGGGGAGCTAACGATGCCGGACGAACTCCCCGCGGTCGACTTGGTAGTGGCCGGATCCGTGGCGG
TAGCTCCGGACGGTGCCAGGGTTGGAAAAGGTGGCGGCTACTTCGACTTGGAGTGGGGGATTTTGGCGCAATTGGATCTC
GTAGATGAAGACACTCCCATACACACTACCGTTCACGATATCCAGGTACTTCCACCGGGAGAGATACCGATGGAAGAGCA
CGACGTACCGGTAGACGTCATCCACACGCCGACGGGGACGACGGAGTGCGTTCGACGCTACGAGAAGCCCGGGGGTCTCT
TGGAAGACCGCATCGACGAGAAAATTAGGGAGATAAGGTGGTTGCGGGAGTACGTTTCAGCCGGAAGCACGTAA

Upstream 100 bases:

>100_bases
AGATCACTGACCTTCATCACTCGCAAAATCACTCGAGATCCGAAGGCAAAAACACCCTATCTCCACTTAAAAGTGAGGCT
TCTCAAGGGGTTGTGGGCAC

Downstream 100 bases:

>100_bases
CGCGTCGGCAAGTTCGGCCAAGGCCTTCTCGAGTTCGTCCTCTCCGATCACGAGCGGAGGTACTAGTCTGATCACGTCAC
CAGAGGTTACGTTCACGAGA

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: 5-Formyltetrahydrofolate Cyclo-Ligase-Related Protein; 5-Formyltetrahydrofolate Cyclo-Ligase-Like

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTSTEKARIRRMVWEELEESGEAAPPFPVEGRIPNFKGALVAARRLTSTPEYEEAEVVKVNPDSPQRPVRERALRDGKIL
IMPTPRLKRGFLVVKNPKDPRRASTIRGAFQEGELTMPDELPAVDLVVAGSVAVAPDGARVGKGGGYFDLEWGILAQLDL
VDEDTPIHTTVHDIQVLPPGEIPMEEHDVPVDVIHTPTGTTECVRRYEKPGGLLEDRIDEKIREIRWLREYVSAGST

Sequences:

>Translated_237_residues
MTSTEKARIRRMVWEELEESGEAAPPFPVEGRIPNFKGALVAARRLTSTPEYEEAEVVKVNPDSPQRPVRERALRDGKIL
IMPTPRLKRGFLVVKNPKDPRRASTIRGAFQEGELTMPDELPAVDLVVAGSVAVAPDGARVGKGGGYFDLEWGILAQLDL
VDEDTPIHTTVHDIQVLPPGEIPMEEHDVPVDVIHTPTGTTECVRRYEKPGGLLEDRIDEKIREIRWLREYVSAGST
>Mature_236_residues
TSTEKARIRRMVWEELEESGEAAPPFPVEGRIPNFKGALVAARRLTSTPEYEEAEVVKVNPDSPQRPVRERALRDGKILI
MPTPRLKRGFLVVKNPKDPRRASTIRGAFQEGELTMPDELPAVDLVVAGSVAVAPDGARVGKGGGYFDLEWGILAQLDLV
DEDTPIHTTVHDIQVLPPGEIPMEEHDVPVDVIHTPTGTTECVRRYEKPGGLLEDRIDEKIREIRWLREYVSAGST

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI226823322, Length=235, Percent_Identity=40.4255319148936, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI226823324, Length=235, Percent_Identity=40.4255319148936, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI226823319, Length=235, Percent_Identity=38.7234042553192, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI116875838, Length=235, Percent_Identity=38.7234042553192, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI226823326, Length=223, Percent_Identity=39.0134529147982, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI161078016, Length=225, Percent_Identity=30.6666666666667, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21355167, Length=227, Percent_Identity=30.3964757709251, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26359; Mature: 26228

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTEKARIRRMVWEELEESGEAAPPFPVEGRIPNFKGALVAARRLTSTPEYEEAEVVKV
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEE
NPDSPQRPVRERALRDGKILIMPTPRLKRGFLVVKNPKDPRRASTIRGAFQEGELTMPDE
CCCCCCCHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCC
LPAVDLVVAGSVAVAPDGARVGKGGGYFDLEWGILAQLDLVDEDTPIHTTVHDIQVLPPG
CCEEEEEEECCEEECCCCCEECCCCCEEEECCCEEEEEEECCCCCCCEEEEEEEEEECCC
EIPMEEHDVPVDVIHTPTGTTECVRRYEKPGGLLEDRIDEKIREIRWLREYVSAGST
CCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSTEKARIRRMVWEELEESGEAAPPFPVEGRIPNFKGALVAARRLTSTPEYEEAEVVKV
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEE
NPDSPQRPVRERALRDGKILIMPTPRLKRGFLVVKNPKDPRRASTIRGAFQEGELTMPDE
CCCCCCCHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCC
LPAVDLVVAGSVAVAPDGARVGKGGGYFDLEWGILAQLDLVDEDTPIHTTVHDIQVLPPG
CCEEEEEEECCEEECCCCCEECCCCCEEEECCCEEEEEEECCCCCCCEEEEEEEEEECCC
EIPMEEHDVPVDVIHTPTGTTECVRRYEKPGGLLEDRIDEKIREIRWLREYVSAGST
CCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA