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The map label for this gene is rfk

Identifier: 20094834

GI number: 20094834

Start: 1422654

End: 1423097

Strand: Reverse

Name: rfk

Synonym: MK1398

Alternate gene names: 20094834

Gene position: 1423097-1422654 (Counterclockwise)

Preceding gene: 20094835

Following gene: 20094833

Centisome position: 83.96

GC content: 59.23

Gene sequence:

>444_bases
GTGTTTACGGGACCGATCGTGGCCGTAGGTGAATATGTGGAGGGACTGGGTGAAGGCCGTCGCTACGTCAGTATTCCTTA
TTACCGGAGGGAAATCGAACGTGTGATCGGGGCGCGACCGTTCCCGGGGACGTTCAACGTCCGTGTAGAGCGCGAGGAGC
GTGAATCGCTCCGTGAGCTCGCGTCTTCATACGGGTACCGAATAGAGCCTCACGGCGAGTACGGAGGAGCTTGGCTTTAT
CCTTGCTTGGTGAACGGAAGGCCCGCGTGGCTGGTCTTTCCGGACCTCACGGAGCACCGGGATCAGGTGGAGCTGATATC
CGAGACGGAGTTACGACGTGAGCTCAACGTAATCCATGGCGATATGGTAAAGATCGAGGTGTGGGGACCGTCGACTTGGA
AGCTAGCGAGGAGGTTGACCTGCGGACCGTCCGGCGGGCGTTGA

Upstream 100 bases:

>100_bases
GAGACACTCCGGCGGGACGTGAAGAACCTCGTATCGTTCTTCGAGCGGAAGTACGGGGTGTCGGCGGACGTAGACGAGGT
CGTAGAGAGGGTGAGGCGAG

Downstream 100 bases:

>100_bases
GACGTGGAGAACCCGTGTTCATTTTCGATTCAGAGGATCGTGAAGGTGAAACCGATATGGTGTTTTGGGCACCTGAAGTC
ACGCCGGATCACGTCGCGGA

Product: riboflavin/FAD biosynthetic operon transcriptional regulator

Products: NA

Alternate protein names: RFK; CTP-dependent riboflavin kinase; CTP:riboflavin 5'-phosphotransferase; Flavokinase

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MFTGPIVAVGEYVEGLGEGRRYVSIPYYRREIERVIGARPFPGTFNVRVEREERESLRELASSYGYRIEPHGEYGGAWLY
PCLVNGRPAWLVFPDLTEHRDQVELISETELRRELNVIHGDMVKIEVWGPSTWKLARRLTCGPSGGR

Sequences:

>Translated_147_residues
MFTGPIVAVGEYVEGLGEGRRYVSIPYYRREIERVIGARPFPGTFNVRVEREERESLRELASSYGYRIEPHGEYGGAWLY
PCLVNGRPAWLVFPDLTEHRDQVELISETELRRELNVIHGDMVKIEVWGPSTWKLARRLTCGPSGGR
>Mature_147_residues
MFTGPIVAVGEYVEGLGEGRRYVSIPYYRREIERVIGARPFPGTFNVRVEREERESLRELASSYGYRIEPHGEYGGAWLY
PCLVNGRPAWLVFPDLTEHRDQVELISETELRRELNVIHGDMVKIEVWGPSTWKLARRLTCGPSGGR

Specific function: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN)

COG id: COG1339

COG function: function code KH; Transcriptional regulator of a riboflavin/FAD biosynthetic operon

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal riboflavin kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIFK_METKA (Q8TVJ1)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614681.1
- ProteinModelPortal:   Q8TVJ1
- SMR:   Q8TVJ1
- GeneID:   1477993
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1398
- NMPDR:   fig|190192.1.peg.1394
- OMA:   NIDIGQD
- BioCyc:   MKAN190192:MK1398-MONOMER
- HAMAP:   MF_01285
- InterPro:   IPR015865
- InterPro:   IPR002834
- Gene3D:   G3DSA:2.40.30.30

Pfam domain/function: PF01982 CTP-dep_RFKase

EC number: =2.7.1.161

Molecular weight: Translated: 16880; Mature: 16880

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: BINDING 97-97 BINDING 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGPIVAVGEYVEGLGEGRRYVSIPYYRREIERVIGARPFPGTFNVRVEREERESLREL
CCCCCEEHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHH
ASSYGYRIEPHGEYGGAWLYPCLVNGRPAWLVFPDLTEHRDQVELISETELRRELNVIHG
HHHCCCEECCCCCCCCEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
DMVKIEVWGPSTWKLARRLTCGPSGGR
CEEEEEEECCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFTGPIVAVGEYVEGLGEGRRYVSIPYYRREIERVIGARPFPGTFNVRVEREERESLREL
CCCCCEEHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHH
ASSYGYRIEPHGEYGGAWLYPCLVNGRPAWLVFPDLTEHRDQVELISETELRRELNVIHG
HHHCCCEECCCCCCCCEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
DMVKIEVWGPSTWKLARRLTCGPSGGR
CEEEEEEECCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014