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The map label for this gene is ribB [H]

Identifier: 20094833

GI number: 20094833

Start: 1422004

End: 1422678

Strand: Reverse

Name: ribB [H]

Synonym: MK1397

Alternate gene names: 20094833

Gene position: 1422678-1422004 (Counterclockwise)

Preceding gene: 20094834

Following gene: 20094832

Centisome position: 83.94

GC content: 61.48

Gene sequence:

>675_bases
CTGCGGACCGTCCGGCGGGCGTTGAGACGTGGAGAACCCGTGTTCATTTTCGATTCAGAGGATCGTGAAGGTGAAACCGA
TATGGTGTTTTGGGCACCTGAAGTCACGCCGGATCACGTCGCGGAACTCCGGAGGACCGCGGGTGGATTGATCTGCGTGG
TAATACATCCGGAGCATGCCCGGGAGATACGCTTACCCTTCCTGGTAGACGTCTACGAACGTGCCGATCATCCCCTACTG
CGCGCCACGTGGCCCGACGATATACCGTACGACGAGCGCTCCACGTTCTCGATCACCGTGAACCACCGAGACACCTTCAC
CGGGGTCACCGACGAGGATCGTGCCTTAACTGTACGGAAACTGGCGGAGTTCTTCACCCGCAACCATGAAGATCCCGTAC
GTGAGTTCGGTGAGGAGTTCAGATCGCCGGGGCACGTGCACCTGCTGCGCCCCTTCGACGGACTGCTGGAGGAACGCCGG
GGACACACCGAGCTCACCGCGACGTTACTCGAACTCGTCGGCTTGGAGCCAAAGGTAGCGGTCATATGCGAGATGCTGGA
GCCGGGTGGAGGAGCGCTCCCACGTGAAGAAGCCGAGCGCGTCGCGAGAGAGCGTGGTGCTCCGTTCCTGACCGGCGAGG
ACATCCTGAAGGCGTGGAAGGGGGGCGAGAGGTGA

Upstream 100 bases:

>100_bases
CCGAGACGGAGTTACGACGTGAGCTCAACGTAATCCATGGCGATATGGTAAAGATCGAGGTGTGGGGACCGTCGACTTGG
AAGCTAGCGAGGAGGTTGAC

Downstream 100 bases:

>100_bases
TCCGCTACATCGTCACTGTGTTGGTGGTGGCGTCCCTCCTGGCGGCTCCGGTCGCCGCTCAGGAGGGAGGTACCACGACG
GGGACCGGACAAGCGACTCC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MRTVRRALRRGEPVFIFDSEDREGETDMVFWAPEVTPDHVAELRRTAGGLICVVIHPEHAREIRLPFLVDVYERADHPLL
RATWPDDIPYDERSTFSITVNHRDTFTGVTDEDRALTVRKLAEFFTRNHEDPVREFGEEFRSPGHVHLLRPFDGLLEERR
GHTELTATLLELVGLEPKVAVICEMLEPGGGALPREEAERVARERGAPFLTGEDILKAWKGGER

Sequences:

>Translated_224_residues
MRTVRRALRRGEPVFIFDSEDREGETDMVFWAPEVTPDHVAELRRTAGGLICVVIHPEHAREIRLPFLVDVYERADHPLL
RATWPDDIPYDERSTFSITVNHRDTFTGVTDEDRALTVRKLAEFFTRNHEDPVREFGEEFRSPGHVHLLRPFDGLLEERR
GHTELTATLLELVGLEPKVAVICEMLEPGGGALPREEAERVARERGAPFLTGEDILKAWKGGER
>Mature_224_residues
MRTVRRALRRGEPVFIFDSEDREGETDMVFWAPEVTPDHVAELRRTAGGLICVVIHPEHAREIRLPFLVDVYERADHPLL
RATWPDDIPYDERSTFSITVNHRDTFTGVTDEDRALTVRKLAEFFTRNHEDPVREFGEEFRSPGHVHLLRPFDGLLEERR
GHTELTATLLELVGLEPKVAVICEMLEPGGGALPREEAERVARERGAPFLTGEDILKAWKGGER

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=219, Percent_Identity=29.6803652968037, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320695, Length=218, Percent_Identity=28.8990825688073, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 25641; Mature: 25641

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVRRALRRGEPVFIFDSEDREGETDMVFWAPEVTPDHVAELRRTAGGLICVVIHPEHA
CHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCC
REIRLPFLVDVYERADHPLLRATWPDDIPYDERSTFSITVNHRDTFTGVTDEDRALTVRK
CCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
LAEFFTRNHEDPVREFGEEFRSPGHVHLLRPFDGLLEERRGHTELTATLLELVGLEPKVA
HHHHHHCCCCCHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
VICEMLEPGGGALPREEAERVARERGAPFLTGEDILKAWKGGER
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MRTVRRALRRGEPVFIFDSEDREGETDMVFWAPEVTPDHVAELRRTAGGLICVVIHPEHA
CHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCC
REIRLPFLVDVYERADHPLLRATWPDDIPYDERSTFSITVNHRDTFTGVTDEDRALTVRK
CCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
LAEFFTRNHEDPVREFGEEFRSPGHVHLLRPFDGLLEERRGHTELTATLLELVGLEPKVA
HHHHHHCCCCCHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
VICEMLEPGGGALPREEAERVARERGAPFLTGEDILKAWKGGER
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]