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The map label for this gene is era [H]

Identifier: 20094209

GI number: 20094209

Start: 734033

End: 734974

Strand: Reverse

Name: era [H]

Synonym: MK0772

Alternate gene names: 20094209

Gene position: 734974-734033 (Counterclockwise)

Preceding gene: 20094210

Following gene: 20094204

Centisome position: 43.36

GC content: 57.43

Gene sequence:

>942_bases
GTGGGAATCGAGGTAAAGGAGATCCGGCCCGGCCGCGGACGTCCTGAACTCGTCTACGCCCGAGCAGAACTCGTGGTCCA
TAAGGAATCGCTGAAGGCTACCCTCATCGGTCGCGAGGGCAGCACCATCCGAGAGATCGGCAAGCGGGCCCGTGAACTCC
TGGAGGAACGCGTCGGAAAGCCTTTCTACCTAGATCTAACCGTCGTAGTCGACCCGAAGAGGTCACCCACTAACCGGTGG
TTCAAGGTACGAGACTCTTCGGAAGCCTGGTTGTGCCCCGCCTTCAAACACCCTCACCTCGTGTCCGTGAGGGAATCCAG
AATACGCGGCAACGCCCGAGTGGCGGCGTTCGTGGAGCTGGAGCACGTCACAGTCCACGGAGGCGCCATGATCTCGAACT
TCTCTTCGATCCGTCGCTCAGTGTTACACAAACGGGTTTCCGTGTCCTCACACTGTGAAATCGAACGCTCGGAACTCGGC
CCGGTGACTTTCGTCGGAGATGGAGCAGAGATCCATGGGTGTAAAATCGAGGAGCGGTGTTTCGTGGGCATGAATGCACG
CCTCTCGCGCTGTGAAATCGGGAGATGGTCCGTAGTAGGTGCGGGAGCTCACATCAGCGACTCGCGCGTTCCTGAGCGTA
GTCTAGTTGTCGGCAACAGCATTGTAGACCGTCTCGACGTTTACACTCTAGTGGTTGGCAAGCGACTCAAACTGGAACTG
AACGGTGGCGAAATATGGTCAGGGCAAGGTGAGAAGTACTACGTCTGTTACCTGCCTGAAGACAATAGAATCACAGTCCG
TCCTGAACCCACGGAGAGGGTTCTGTGCGAAGTTCGGAAAGCCAACGATAAATGGGAGGTGAGAGGGGAAGGGTTCGTTC
GCACGGTCCGAGGGTCGTCGCTACACTGGTACGTGGGACATGAGCGAGGGCTACTGGGTTAG

Upstream 100 bases:

>100_bases
AACTACGAGTACTACATCGCACCTACCGAGTGAACGCACCGTCGAGAGAGCCCTGCGCTCGGCCTTACGCGAAGTACTCC
ACGGATCACTCCCACGGGAA

Downstream 100 bases:

>100_bases
ACCTTCAGAGATTCTCGCAGTTCCTTCACGATCTCCGCGATGTCCATCTTGGTGACCCTGTTCAACACGAACTTAGCGTC
TTTCTCCGACTTCGCTAGAT

Product: carbonic anhydrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MGIEVKEIRPGRGRPELVYARAELVVHKESLKATLIGREGSTIREIGKRARELLEERVGKPFYLDLTVVVDPKRSPTNRW
FKVRDSSEAWLCPAFKHPHLVSVRESRIRGNARVAAFVELEHVTVHGGAMISNFSSIRRSVLHKRVSVSSHCEIERSELG
PVTFVGDGAEIHGCKIEERCFVGMNARLSRCEIGRWSVVGAGAHISDSRVPERSLVVGNSIVDRLDVYTLVVGKRLKLEL
NGGEIWSGQGEKYYVCYLPEDNRITVRPEPTERVLCEVRKANDKWEVRGEGFVRTVRGSSLHWYVGHERGLLG

Sequences:

>Translated_313_residues
MGIEVKEIRPGRGRPELVYARAELVVHKESLKATLIGREGSTIREIGKRARELLEERVGKPFYLDLTVVVDPKRSPTNRW
FKVRDSSEAWLCPAFKHPHLVSVRESRIRGNARVAAFVELEHVTVHGGAMISNFSSIRRSVLHKRVSVSSHCEIERSELG
PVTFVGDGAEIHGCKIEERCFVGMNARLSRCEIGRWSVVGAGAHISDSRVPERSLVVGNSIVDRLDVYTLVVGKRLKLEL
NGGEIWSGQGEKYYVCYLPEDNRITVRPEPTERVLCEVRKANDKWEVRGEGFVRTVRGSSLHWYVGHERGLLG
>Mature_312_residues
GIEVKEIRPGRGRPELVYARAELVVHKESLKATLIGREGSTIREIGKRARELLEERVGKPFYLDLTVVVDPKRSPTNRWF
KVRDSSEAWLCPAFKHPHLVSVRESRIRGNARVAAFVELEHVTVHGGAMISNFSSIRRSVLHKRVSVSSHCEIERSELGP
VTFVGDGAEIHGCKIEERCFVGMNARLSRCEIGRWSVVGAGAHISDSRVPERSLVVGNSIVDRLDVYTLVVGKRLKLELN
GGEIWSGQGEKYYVCYLPEDNRITVRPEPTERVLCEVRKANDKWEVRGEGFVRTVRGSSLHWYVGHERGLLG

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. The GTPase is stimulated about 6-fo

COG id: COG0663

COG function: function code R; Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 35284; Mature: 35153

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIEVKEIRPGRGRPELVYARAELVVHKESLKATLIGREGSTIREIGKRARELLEERVGK
CCCEEEECCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
PFYLDLTVVVDPKRSPTNRWFKVRDSSEAWLCPAFKHPHLVSVRESRIRGNARVAAFVEL
CEEEEEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCEEEEEHHHHCCCCCEEEEEEEE
EHVTVHGGAMISNFSSIRRSVLHKRVSVSSHCEIERSELGPVTFVGDGAEIHGCKIEERC
EEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCEEEEECCCEEECEEECCEE
FVGMNARLSRCEIGRWSVVGAGAHISDSRVPERSLVVGNSIVDRLDVYTLVVGKRLKLEL
EECCCCCCCEECCCCEEEEECCCCCCCCCCCCCEEEECHHHHHHHHHEEEEECCEEEEEE
NGGEIWSGQGEKYYVCYLPEDNRITVRPEPTERVLCEVRKANDKWEVRGEGFVRTVRGSS
CCCEEECCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEECCCEEEEECCCE
LHWYVGHERGLLG
EEEEECCCCCCCC
>Mature Secondary Structure 
GIEVKEIRPGRGRPELVYARAELVVHKESLKATLIGREGSTIREIGKRARELLEERVGK
CCEEEECCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
PFYLDLTVVVDPKRSPTNRWFKVRDSSEAWLCPAFKHPHLVSVRESRIRGNARVAAFVEL
CEEEEEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCEEEEEHHHHCCCCCEEEEEEEE
EHVTVHGGAMISNFSSIRRSVLHKRVSVSSHCEIERSELGPVTFVGDGAEIHGCKIEERC
EEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCEEEEECCCEEECEEECCEE
FVGMNARLSRCEIGRWSVVGAGAHISDSRVPERSLVVGNSIVDRLDVYTLVVGKRLKLEL
EECCCCCCCEECCCCEEEEECCCCCCCCCCCCCEEEECHHHHHHHHHEEEEECCEEEEEE
NGGEIWSGQGEKYYVCYLPEDNRITVRPEPTERVLCEVRKANDKWEVRGEGFVRTVRGSS
CCCEEECCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEECCCEEEEECCCE
LHWYVGHERGLLG
EEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]