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The map label for this gene is RPP30

Identifier: 20093825

GI number: 20093825

Start: 371086

End: 371820

Strand: Reverse

Name: RPP30

Synonym: MK0387

Alternate gene names: 20093825

Gene position: 371820-371086 (Counterclockwise)

Preceding gene: 20093826

Following gene: 20093824

Centisome position: 21.94

GC content: 58.64

Gene sequence:

>735_bases
TTGAGGGTTTCCGAGAACTTCGCCCTTCGAGTTCACGTCGACGAGGTAGACCCCCTGAGGATGGCTCTGGCCGCCGAGCG
TTTGGACTACGAGATCGCCGTCCTCTGTCTGGAGCTGGAAGCAGAGCGTCTGAATATTGACGATCTGAGGTGGCTCATCG
AGGAGATCCGGGATATCCGTGAACACGTTGAGAGCGTGCTCGTCCTACCCGGCTGCAAATTGGAGGCGGAGTCTGCGGGG
GCTCTCCGTAGAGCGATCCGCCGAACACGACCCCTCGTGTACTTACTCGCCGTCGGCGGCGGCGACCCTAAAATCAATCG
AGCTGCTGTCTCCGATACTAGGGTGGATCTGCTATCACATCCAGAGCGCGGTAATCCCCACGCTGGTTTGGGTAAGTACG
AGATCGAGCTGGCACGGGAGAAGTGGACTTACGTGGAGATCGACCTATCGAGACTGTTCCGACGGGAGGGCGAGCGACTC
GCGTGGCAGGTCTCTCGAATTCGCGATCTCTTACGCTTGCGCCGTAGGAAACGGTTTCCGACGACCGTGGCGCTGGGCGC
ACGTGATCCACTGGAATTGATCAGACCGAAGCAGGTGGAGGATCTCCTGAAACTTATGGGGTTTGAAGATAGCGAGGTGA
AGGAGATGTGTGTCGAGGCTCCCAGGGAAATCCTCCGGTGGAACGCGGCGTGTAAGCACGTTTTCACAGTGCCAGGCGTC
GTCTCACTGGGGTGA

Upstream 100 bases:

>100_bases
CAGACGATGTGATCAGGGTGAAAGTCAACCTGGAGAGCTACCCTGCGAGCCGCGAGGGGGGCATAAAGACGCTAGAGCGG
CTCGGTATCTTCTCCAACGA

Downstream 100 bases:

>100_bases
AACACATGCGTGTGCGTCTGTCCTCCGCACTCCGCCCCAGATGGCGTTATGTAACGTTCAAGGTATGGTCGGAGCGCGTC
GAAGCGCTGGACTTCGGGGG

Product: ribonuclease P subunit Rpp30

Products: NA

Alternate protein names: RNase P component 3

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MRVSENFALRVHVDEVDPLRMALAAERLDYEIAVLCLELEAERLNIDDLRWLIEEIRDIREHVESVLVLPGCKLEAESAG
ALRRAIRRTRPLVYLLAVGGGDPKINRAAVSDTRVDLLSHPERGNPHAGLGKYEIELAREKWTYVEIDLSRLFRREGERL
AWQVSRIRDLLRLRRRKRFPTTVALGARDPLELIRPKQVEDLLKLMGFEDSEVKEMCVEAPREILRWNAACKHVFTVPGV
VSLG

Sequences:

>Translated_244_residues
MRVSENFALRVHVDEVDPLRMALAAERLDYEIAVLCLELEAERLNIDDLRWLIEEIRDIREHVESVLVLPGCKLEAESAG
ALRRAIRRTRPLVYLLAVGGGDPKINRAAVSDTRVDLLSHPERGNPHAGLGKYEIELAREKWTYVEIDLSRLFRREGERL
AWQVSRIRDLLRLRRRKRFPTTVALGARDPLELIRPKQVEDLLKLMGFEDSEVKEMCVEAPREILRWNAACKHVFTVPGV
VSLG
>Mature_244_residues
MRVSENFALRVHVDEVDPLRMALAAERLDYEIAVLCLELEAERLNIDDLRWLIEEIRDIREHVESVLVLPGCKLEAESAG
ALRRAIRRTRPLVYLLAVGGGDPKINRAAVSDTRVDLLSHPERGNPHAGLGKYEIELAREKWTYVEIDLSRLFRREGERL
AWQVSRIRDLLRLRRRKRFPTTVALGARDPLELIRPKQVEDLLKLMGFEDSEVKEMCVEAPREILRWNAACKHVFTVPGV
VSLG

Specific function: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends

COG id: COG1603

COG function: function code J; RNase P/RNase MRP subunit p30

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic/archaeal RNase P protein component 3 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNP3_METKA (Q8TYB5)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613672.1
- ProteinModelPortal:   Q8TYB5
- GeneID:   1477690
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0387
- NMPDR:   fig|190192.1.peg.385
- BioCyc:   MKAN190192:MK0387-MONOMER
- BRENDA:   3.1.26.5
- HAMAP:   MF_00756
- InterPro:   IPR016195
- InterPro:   IPR002738

Pfam domain/function: PF01876 RNase_P_p30; SSF89550 PHP-like

EC number: =3.1.26.5

Molecular weight: Translated: 28043; Mature: 28043

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSENFALRVHVDEVDPLRMALAAERLDYEIAVLCLELEAERLNIDDLRWLIEEIRDIR
CCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEEHHHHHCCHHHHHHHHHHHHHHH
EHVESVLVLPGCKLEAESAGALRRAIRRTRPLVYLLAVGGGDPKINRAAVSDTRVDLLSH
HHHHHEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHCHHHHHHHCC
PERGNPHAGLGKYEIELAREKWTYVEIDLSRLFRREGERLAWQVSRIRDLLRLRRRKRFP
CCCCCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
TTVALGARDPLELIRPKQVEDLLKLMGFEDSEVKEMCVEAPREILRWNAACKHVFTVPGV
CEEEECCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCE
VSLG
EECC
>Mature Secondary Structure
MRVSENFALRVHVDEVDPLRMALAAERLDYEIAVLCLELEAERLNIDDLRWLIEEIRDIR
CCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEEHHHHHCCHHHHHHHHHHHHHHH
EHVESVLVLPGCKLEAESAGALRRAIRRTRPLVYLLAVGGGDPKINRAAVSDTRVDLLSH
HHHHHEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHCHHHHHHHCC
PERGNPHAGLGKYEIELAREKWTYVEIDLSRLFRREGERLAWQVSRIRDLLRLRRRKRFP
CCCCCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
TTVALGARDPLELIRPKQVEDLLKLMGFEDSEVKEMCVEAPREILRWNAACKHVFTVPGV
CEEEECCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCE
VSLG
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014