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The map label for this gene is CobT

Identifier: 20093664

GI number: 20093664

Start: 211590

End: 212726

Strand: Direct

Name: CobT

Synonym: MK0224

Alternate gene names: NA

Gene position: 211590-212726 (Clockwise)

Preceding gene: 20093663

Following gene: 20093668

Centisome position: 12.48

GC content: 58.75

Gene sequence:

>1137_bases
ATGCCGAACGCTAACCAAGCTTCCGCGGGTGTGGGAGCGTTGAAGGAAGTCCTACCGGGTATTCGAGCGCTGGGAGATCT
AGAAGCCGCGGAGAAAGTCGTCAAGAGGTGCTCCGGTGGAAGCACGGTGATGGTGTGTGTGATCGGTAGTACCGAAATCA
GCCGCGTTCCCGGTATCTCAGCCGCGGGTAAAACGCCGGAGTCAACCTTTCACACACCCGCAGGAGATGTCGAGTTGATA
TACTACGACAGGATCATCAACGCCGAGGAGGTCCCACAGAACCCCGTGGGTGCTCCCTCACCCGCGGTGATAACGAAAGC
CGTCGTGAACTTGGCGTCTATCCCCTTCTTGACGGTGGATGCCGGGGCAGCCGTGAAACCCGCTTGCCCCTACATCGACC
TCGGAGGTGAGGTCGCGAGGGACTTCCGCGAAGGGCCGGCACTGTCGGAGGAAACCTACGACAGACTGCTGGAGTTCGGT
AAAACGCTCGGTAAGGAGCTCACCCGCGATGTGGACTTCCTAACCGTGGGGGAAAGCGTGCCGGGCGGGACTACCACGGC
GATGGCCGTGATGACTGCGTTGGGTTACGAAACCAGTGAAAAGTTCGCGAGCAGCTCCCACGATTCTCCGCACGATATCA
AGGAGCGCGTGGTGAAAGAAGGCCTGGAGGCGCAAGGAGTAGAACCGGGTGACTTGGACGCCCACGAGGCGATCAGGAGG
TTCGGAGATCCTATGATGCCTGCGGTGGTAGGCATCATCTACGGGTCCAGGACACCGGTGCTCTTGGCGGGTGGCACGCA
GATGGCCCCAATCCTAGCGTATCTGGCGGAGGAAGGACAGTTGGACCCGGAACGGGTATTCGTCGGAACTACCAAATACG
TGGTCGAAGACGAGGACTCCGACATCGAAAGTCTGTTCCGGCAAGTGGGTGACTACGTTCTATTCTCCGCGGACCCCGGG
TTCTCGGAGTCCAAGTTCCGTGGGTTCAGGTTGTACGAGGAAGGGTACGTAAAGGAGGGTGTCGGTGCCGGTGGGGCTCA
GGTAGCAGCTGCGTTGAAAACGAAAGGAGAGATCACACCGAAAGACGTTCTGAGGGAGTGCGAGCGGGTTTACGAGCGGT
GGATGGATAAATTTTAA

Upstream 100 bases:

>100_bases
GTCGATTGCCGGAGGGAGCCGTGATCACCGTAGAGCCCGGGCTTTACTCGGATGAGTTCGGGATCCGCGTCGAGGAAATG
GTGGTCGTCGGGAAGCGAAA

Downstream 100 bases:

>100_bases
CTAAATAACTTTTCTACCAAAGTACGCTCAAACCTACGATGCTCTAAGAAGTGGTTATTAGGATCTTTTATTAATATGTA
GACTAAGTAAGGGTACAGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MPNANQASAGVGALKEVLPGIRALGDLEAAEKVVKRCSGGSTVMVCVIGSTEISRVPGISAAGKTPESTFHTPAGDVELI
YYDRIINAEEVPQNPVGAPSPAVITKAVVNLASIPFLTVDAGAAVKPACPYIDLGGEVARDFREGPALSEETYDRLLEFG
KTLGKELTRDVDFLTVGESVPGGTTTAMAVMTALGYETSEKFASSSHDSPHDIKERVVKEGLEAQGVEPGDLDAHEAIRR
FGDPMMPAVVGIIYGSRTPVLLAGGTQMAPILAYLAEEGQLDPERVFVGTTKYVVEDEDSDIESLFRQVGDYVLFSADPG
FSESKFRGFRLYEEGYVKEGVGAGGAQVAAALKTKGEITPKDVLRECERVYERWMDKF

Sequences:

>Translated_378_residues
MPNANQASAGVGALKEVLPGIRALGDLEAAEKVVKRCSGGSTVMVCVIGSTEISRVPGISAAGKTPESTFHTPAGDVELI
YYDRIINAEEVPQNPVGAPSPAVITKAVVNLASIPFLTVDAGAAVKPACPYIDLGGEVARDFREGPALSEETYDRLLEFG
KTLGKELTRDVDFLTVGESVPGGTTTAMAVMTALGYETSEKFASSSHDSPHDIKERVVKEGLEAQGVEPGDLDAHEAIRR
FGDPMMPAVVGIIYGSRTPVLLAGGTQMAPILAYLAEEGQLDPERVFVGTTKYVVEDEDSDIESLFRQVGDYVLFSADPG
FSESKFRGFRLYEEGYVKEGVGAGGAQVAAALKTKGEITPKDVLRECERVYERWMDKF
>Mature_377_residues
PNANQASAGVGALKEVLPGIRALGDLEAAEKVVKRCSGGSTVMVCVIGSTEISRVPGISAAGKTPESTFHTPAGDVELIY
YDRIINAEEVPQNPVGAPSPAVITKAVVNLASIPFLTVDAGAAVKPACPYIDLGGEVARDFREGPALSEETYDRLLEFGK
TLGKELTRDVDFLTVGESVPGGTTTAMAVMTALGYETSEKFASSSHDSPHDIKERVVKEGLEAQGVEPGDLDAHEAIRRF
GDPMMPAVVGIIYGSRTPVLLAGGTQMAPILAYLAEEGQLDPERVFVGTTKYVVEDEDSDIESLFRQVGDYVLFSADPGF
SESKFRGFRLYEEGYVKEGVGAGGAQVAAALKTKGEITPKDVLRECERVYERWMDKF

Specific function: Unknown

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0284 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y224_METKA (Q8TYR8)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613511.1
- ProteinModelPortal:   Q8TYR8
- SMR:   Q8TYR8
- GeneID:   1477527
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0224
- NMPDR:   fig|190192.1.peg.224
- HOGENOM:   HBG497525
- OMA:   QMLAVYA
- ProtClustDB:   PRK04447
- BioCyc:   MKAN190192:MK0224-MONOMER
- HAMAP:   MF_01086
- InterPro:   IPR003200
- InterPro:   IPR002805
- TIGRFAMs:   TIGR00303

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: NA

Molecular weight: Translated: 40330; Mature: 40199

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNANQASAGVGALKEVLPGIRALGDLEAAEKVVKRCSGGSTVMVCVIGSTEISRVPGIS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHCCCCC
AAGKTPESTFHTPAGDVELIYYDRIINAEEVPQNPVGAPSPAVITKAVVNLASIPFLTVD
CCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
AGAAVKPACPYIDLGGEVARDFREGPALSEETYDRLLEFGKTLGKELTRDVDFLTVGESV
CCCCCCCCCCEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
PGGTTTAMAVMTALGYETSEKFASSSHDSPHDIKERVVKEGLEAQGVEPGDLDAHEAIRR
CCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHH
FGDPMMPAVVGIIYGSRTPVLLAGGTQMAPILAYLAEEGQLDPERVFVGTTKYVVEDEDS
HCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHEEEECEEEEEECCCC
DIESLFRQVGDYVLFSADPGFSESKFRGFRLYEEGYVKEGVGAGGAQVAAALKTKGEITP
HHHHHHHHHCCEEEEECCCCCCHHHCCCEEEHHHCCHHCCCCCCHHHHHHHHHHCCCCCH
KDVLRECERVYERWMDKF
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PNANQASAGVGALKEVLPGIRALGDLEAAEKVVKRCSGGSTVMVCVIGSTEISRVPGIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHCCCCC
AAGKTPESTFHTPAGDVELIYYDRIINAEEVPQNPVGAPSPAVITKAVVNLASIPFLTVD
CCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
AGAAVKPACPYIDLGGEVARDFREGPALSEETYDRLLEFGKTLGKELTRDVDFLTVGESV
CCCCCCCCCCEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
PGGTTTAMAVMTALGYETSEKFASSSHDSPHDIKERVVKEGLEAQGVEPGDLDAHEAIRR
CCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHH
FGDPMMPAVVGIIYGSRTPVLLAGGTQMAPILAYLAEEGQLDPERVFVGTTKYVVEDEDS
HCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHEEEECEEEEEECCCC
DIESLFRQVGDYVLFSADPGFSESKFRGFRLYEEGYVKEGVGAGGAQVAAALKTKGEITP
HHHHHHHHHCCEEEEECCCCCCHHHCCCEEEHHHCCHHCCCCCCHHHHHHHHHHCCCCCH
KDVLRECERVYERWMDKF
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014