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The map label for this gene is PepP [H]

Identifier: 20093663

GI number: 20093663

Start: 210649

End: 211632

Strand: Direct

Name: PepP [H]

Synonym: MK0223

Alternate gene names: 20093663

Gene position: 210649-211632 (Clockwise)

Preceding gene: 20093662

Following gene: 20093664

Centisome position: 12.43

GC content: 59.45

Gene sequence:

>984_bases
CTGAAGTCTGATGATTTCTTTCTAGAGAAGGTGGAGAAGCTCGAGGAGCTCGCAGAAGGTGAACCCTGTGCCCTCGTCAG
GCGCCAAAACGTTGAGTGGATAACCCATTTTCCCGGTCTAGCGTTCCACGCCGACTTCGAGTCCGAAGAGTACACGCTGG
TTGTCCACCGTATGGATTCGAGGGCCGTTCGGGAGTGGCCGATTCCGGAGACCGTCGAAGTCATCACACACGATGAGGCC
AACCGCCTGACTCCCGCCCGGGCCGTCGACGACGAGTCGGCGGCCCGCAAGGTACCCTGTTATAGGGTGAAGAACGTTAA
CGAGGACGTTACGAGGGCGCGTCTCTCCAAGTCGAAGAGTGAGCTGAGGTTCATTGAGGAGCTAGTGGAAGCGACCGAGC
GGATACTCGTAAAAGTTCTCCCACCCGAAGACTCGGAGGCCGAGGTAGCATCCGACCTCATAAGGGAGGCCACGATTCGC
GGCTTTCAAACGGCATTCGACCCTATAGTGGCGTATGACGAGGGTGCCGGTGTACCCCACCACCGACCGAGTCCCGAGGA
AAAGACCTGGACGAAATGTGCGTTGGTAGATTACGGGATCAAGATGGTGTACTGCACGGACATCACGAGGACCGTAGTGT
CCGAGAACGAGGCGGGAGACGTCCTCGAAGTCGTCGTGAACGCCCTCGAGGAGGCACTCCGAGAGCTTCAGGCGGGTGTG
AACCCGAAGGAGCTCGAGGAAGAGCTGAGAGGGTGGATGGAAGACGAAGCGCCCGGATTCGAGTTCCCCCACAGCCTCGG
CCACCATGTGGGAGTCACGGTCCACGAGGGCCGTCTCATGGGTCGATTGCCGGAGGGAGCCGTGATCACCGTAGAGCCCG
GGCTTTACTCGGATGAGTTCGGGATCCGCGTCGAGGAAATGGTGGTCGTCGGGAAGCGAAAATGCCGAACGCTAACCAAG
CTTCCGCGGGTGTGGGAGCGTTGA

Upstream 100 bases:

>100_bases
TCCAGGGAGGACGCTGTCAGGGTACTAAAGATCTACAAGCTCGCCCGAAAAGTGGTCGATGGCGAGGGGGAGGAGGAAAA
CGAAACGACTCCAGGAGATC

Downstream 100 bases:

>100_bases
AGGAAGTCCTACCGGGTATTCGAGCGCTGGGAGATCTAGAAGCCGCGGAGAAAGTCGTCAAGAGGTGCTCCGGTGGAAGC
ACGGTGATGGTGTGTGTGAT

Product: Xaa-Pro aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKSDDFFLEKVEKLEELAEGEPCALVRRQNVEWITHFPGLAFHADFESEEYTLVVHRMDSRAVREWPIPETVEVITHDEA
NRLTPARAVDDESAARKVPCYRVKNVNEDVTRARLSKSKSELRFIEELVEATERILVKVLPPEDSEAEVASDLIREATIR
GFQTAFDPIVAYDEGAGVPHHRPSPEEKTWTKCALVDYGIKMVYCTDITRTVVSENEAGDVLEVVVNALEEALRELQAGV
NPKELEEELRGWMEDEAPGFEFPHSLGHHVGVTVHEGRLMGRLPEGAVITVEPGLYSDEFGIRVEEMVVVGKRKCRTLTK
LPRVWER

Sequences:

>Translated_327_residues
MKSDDFFLEKVEKLEELAEGEPCALVRRQNVEWITHFPGLAFHADFESEEYTLVVHRMDSRAVREWPIPETVEVITHDEA
NRLTPARAVDDESAARKVPCYRVKNVNEDVTRARLSKSKSELRFIEELVEATERILVKVLPPEDSEAEVASDLIREATIR
GFQTAFDPIVAYDEGAGVPHHRPSPEEKTWTKCALVDYGIKMVYCTDITRTVVSENEAGDVLEVVVNALEEALRELQAGV
NPKELEEELRGWMEDEAPGFEFPHSLGHHVGVTVHEGRLMGRLPEGAVITVEPGLYSDEFGIRVEEMVVVGKRKCRTLTK
LPRVWER
>Mature_327_residues
MKSDDFFLEKVEKLEELAEGEPCALVRRQNVEWITHFPGLAFHADFESEEYTLVVHRMDSRAVREWPIPETVEVITHDEA
NRLTPARAVDDESAARKVPCYRVKNVNEDVTRARLSKSKSELRFIEELVEATERILVKVLPPEDSEAEVASDLIREATIR
GFQTAFDPIVAYDEGAGVPHHRPSPEEKTWTKCALVDYGIKMVYCTDITRTVVSENEAGDVLEVVVNALEEALRELQAGV
NPKELEEELRGWMEDEAPGFEFPHSLGHHVGVTVHEGRLMGRLPEGAVITVEPGLYSDEFGIRVEEMVVVGKRKCRTLTK
LPRVWER

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=195, Percent_Identity=28.7179487179487, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 37113; Mature: 37113

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSDDFFLEKVEKLEELAEGEPCALVRRQNVEWITHFPGLAFHADFESEEYTLVVHRMDS
CCCCHHHHHHHHHHHHHHCCCCEEEHHHCCCCEEECCCCEEEEECCCCCCEEEEEEECCC
RAVREWPIPETVEVITHDEANRLTPARAVDDESAARKVPCYRVKNVNEDVTRARLSKSKS
HHHHCCCCCCHHHHEECCCCCCCCCCCCCCCHHHHHCCCCCEECCCCHHHHHHHHHHHHH
ELRFIEELVEATERILVKVLPPEDSEAEVASDLIREATIRGFQTAFDPIVAYDEGAGVPH
HHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
HRPSPEEKTWTKCALVDYGIKMVYCTDITRTVVSENEAGDVLEVVVNALEEALRELQAGV
CCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
NPKELEEELRGWMEDEAPGFEFPHSLGHHVGVTVHEGRLMGRLPEGAVITVEPGLYSDEF
CHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCEEEECCEEECCCCCCCEEEECCCCCCCCC
GIRVEEMVVVGKRKCRTLTKLPRVWER
CCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSDDFFLEKVEKLEELAEGEPCALVRRQNVEWITHFPGLAFHADFESEEYTLVVHRMDS
CCCCHHHHHHHHHHHHHHCCCCEEEHHHCCCCEEECCCCEEEEECCCCCCEEEEEEECCC
RAVREWPIPETVEVITHDEANRLTPARAVDDESAARKVPCYRVKNVNEDVTRARLSKSKS
HHHHCCCCCCHHHHEECCCCCCCCCCCCCCCHHHHHCCCCCEECCCCHHHHHHHHHHHHH
ELRFIEELVEATERILVKVLPPEDSEAEVASDLIREATIRGFQTAFDPIVAYDEGAGVPH
HHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
HRPSPEEKTWTKCALVDYGIKMVYCTDITRTVVSENEAGDVLEVVVNALEEALRELQAGV
CCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
NPKELEEELRGWMEDEAPGFEFPHSLGHHVGVTVHEGRLMGRLPEGAVITVEPGLYSDEF
CHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCEEEECCEEECCCCCCCEEEECCCCCCCCC
GIRVEEMVVVGKRKCRTLTKLPRVWER
CCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]