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The map label for this gene is rsmB [H]

Identifier: 20093483

GI number: 20093483

Start: 38495

End: 39829

Strand: Reverse

Name: rsmB [H]

Synonym: MK0043

Alternate gene names: 20093483

Gene position: 39829-38495 (Counterclockwise)

Preceding gene: 20093484

Following gene: 20093482

Centisome position: 2.35

GC content: 56.18

Gene sequence:

>1335_bases
GTGAAGGTCAGTGAGATAGTATCTATGCTAGCCAGGATACTCGCTGAGCACTACCGGTCCGGGGTCTCCCTGAAGGAGTC
GTTCTACCGGGCTCTCGACAATCCGTTCTCCATTCCCAGCCATCGGGCTAGGGCCATTCACCGTCGACTTATGGAACTCG
GCAAGCGGTTGGGACTCTGCGAGGAGATCCTCGATGACGTCATTCAATCGGGATCTTTCGAAGATCTTGGTCCGGAGCTG
AAGGGAGTTCTGGTAACCGCAGCTGACGAGATGCTGTTCGAGGGAACTAGTCCGGCGTTGGTAACCGACGCTGCGACGCG
GGTAGCTAAGGAGCTAGTCAGCGATAGAGTGGCCGACTTCGTGCACGCCGTATGTTTCGACCTCGAGAAGTACGACGTAG
ACCGGCTGAAGCGACGCGGTTACGATGACCTTTGCCTGCGGCACTACTTCCCACCCGACTTCGTCGATTACGTCCGCCGC
GTGCTGCCCGAGGACGAGATAGAAGACTTCCTCCGAGCGTGCAACAAACCCGCGGTAAAGTACGTCCGCGTGAACACACT
GCGGGCGGACGTAGACGAAGTCCGCGAGCGCCTGGCGGAGGAGGGTGTGCTGACGGAGCCGGATGAGCACATACCGGACC
TGCTACGTGTAGTCGAGGAGGAGATACCTATAGTCAGAACTGAGGCGTGGAAGGAGGGTCTGGTGTTCACTCAAGATAAG
GCCTCCGCGGCAGTCGCCCACGTACTCGATCCACAACCCGGGGAGTTCGTAGTCGACCTCTGCGCGGCTCCCGGCGGAAA
GACGCTCCATGCCCTCTGTTTGATGGAGGGCGAAGGAGAGATCCTTGCGGTCGACAAATCCGACTGGCGATTGGACGCTA
TGCGGGAGAAGTTGGCGTGGCAGCGTGTTCCCGATGGTGTCGTCGAACTCCGATGTGCGGACGCTCGAGAGATACCGGAG
GAGCTGGATGAAGAGGCCGACCGAGCCATTGTCGATCCTCCATGTTCCGGTATGGGTTCCGTCCAGAAGCGACCGGAAAC
CAGGTGGAACGTCACGAAGAAACGTGTGCGACGTTACGCTAAACTCCAATCAGAATTGTTGGAAGCAGCGATAAAGACCG
TTCGACCTGGAGGTATTGTGGTGTATTCAACATGTACTTTGACTATTAACGAAAATGAAAACGTGATCCGAAGAGTCGCA
AGACGGTACGATGTGACTATTGAGAAGGTGAACCTTCAATTCGGTAGGAGGGGATTAGTTCCGGGAACCCGACGGTTCTA
CCCTCATACCGACCGATGTCAGGGATTTTTCATCGCAAAATTAAGGAAGAACTAA

Upstream 100 bases:

>100_bases
CACCCTAGATCGCCAGCCTAGCGCCTATGAGCTCGTGACGTCTCGTCTCTCCTAAACCTATTTCTTTACGAACGCGACTG
GCCGACCGAAGGGAGGTCGT

Downstream 100 bases:

>100_bases
GGCCGATACTGACACCAGCTCAGTCCACAGAGGCGAACGAAAAGGTTAATTATTCGATTTCAGTCTACTATAAGTGCGGG
GGAATGTAACATGCGAGCCC

Product: tRNA/rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKVSEIVSMLARILAEHYRSGVSLKESFYRALDNPFSIPSHRARAIHRRLMELGKRLGLCEEILDDVIQSGSFEDLGPEL
KGVLVTAADEMLFEGTSPALVTDAATRVAKELVSDRVADFVHAVCFDLEKYDVDRLKRRGYDDLCLRHYFPPDFVDYVRR
VLPEDEIEDFLRACNKPAVKYVRVNTLRADVDEVRERLAEEGVLTEPDEHIPDLLRVVEEEIPIVRTEAWKEGLVFTQDK
ASAAVAHVLDPQPGEFVVDLCAAPGGKTLHALCLMEGEGEILAVDKSDWRLDAMREKLAWQRVPDGVVELRCADAREIPE
ELDEEADRAIVDPPCSGMGSVQKRPETRWNVTKKRVRRYAKLQSELLEAAIKTVRPGGIVVYSTCTLTINENENVIRRVA
RRYDVTIEKVNLQFGRRGLVPGTRRFYPHTDRCQGFFIAKLRKN

Sequences:

>Translated_444_residues
MKVSEIVSMLARILAEHYRSGVSLKESFYRALDNPFSIPSHRARAIHRRLMELGKRLGLCEEILDDVIQSGSFEDLGPEL
KGVLVTAADEMLFEGTSPALVTDAATRVAKELVSDRVADFVHAVCFDLEKYDVDRLKRRGYDDLCLRHYFPPDFVDYVRR
VLPEDEIEDFLRACNKPAVKYVRVNTLRADVDEVRERLAEEGVLTEPDEHIPDLLRVVEEEIPIVRTEAWKEGLVFTQDK
ASAAVAHVLDPQPGEFVVDLCAAPGGKTLHALCLMEGEGEILAVDKSDWRLDAMREKLAWQRVPDGVVELRCADAREIPE
ELDEEADRAIVDPPCSGMGSVQKRPETRWNVTKKRVRRYAKLQSELLEAAIKTVRPGGIVVYSTCTLTINENENVIRRVA
RRYDVTIEKVNLQFGRRGLVPGTRRFYPHTDRCQGFFIAKLRKN
>Mature_444_residues
MKVSEIVSMLARILAEHYRSGVSLKESFYRALDNPFSIPSHRARAIHRRLMELGKRLGLCEEILDDVIQSGSFEDLGPEL
KGVLVTAADEMLFEGTSPALVTDAATRVAKELVSDRVADFVHAVCFDLEKYDVDRLKRRGYDDLCLRHYFPPDFVDYVRR
VLPEDEIEDFLRACNKPAVKYVRVNTLRADVDEVRERLAEEGVLTEPDEHIPDLLRVVEEEIPIVRTEAWKEGLVFTQDK
ASAAVAHVLDPQPGEFVVDLCAAPGGKTLHALCLMEGEGEILAVDKSDWRLDAMREKLAWQRVPDGVVELRCADAREIPE
ELDEEADRAIVDPPCSGMGSVQKRPETRWNVTKKRVRRYAKLQSELLEAAIKTVRPGGIVVYSTCTLTINENENVIRRVA
RRYDVTIEKVNLQFGRRGLVPGTRRFYPHTDRCQGFFIAKLRKN

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=327, Percent_Identity=32.4159021406728, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI76150623, Length=327, Percent_Identity=32.4159021406728, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI32698918, Length=196, Percent_Identity=36.734693877551, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI270288818, Length=310, Percent_Identity=30, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI8922322, Length=306, Percent_Identity=30.3921568627451, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI23199998, Length=306, Percent_Identity=30.3921568627451, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI270288816, Length=306, Percent_Identity=30.3921568627451, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI11545785, Length=238, Percent_Identity=30.672268907563, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI40316918, Length=193, Percent_Identity=33.6787564766839, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI87081985, Length=311, Percent_Identity=31.8327974276527, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI2367212, Length=302, Percent_Identity=29.1390728476821, Blast_Score=118, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17536757, Length=356, Percent_Identity=27.5280898876405, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI71998419, Length=310, Percent_Identity=30.9677419354839, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115534021, Length=216, Percent_Identity=35.6481481481481, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25143471, Length=179, Percent_Identity=29.608938547486, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324268, Length=329, Percent_Identity=29.1793313069909, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6324306, Length=285, Percent_Identity=24.2105263157895, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI22024126, Length=352, Percent_Identity=29.5454545454545, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21356513, Length=246, Percent_Identity=35.3658536585366, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24668781, Length=246, Percent_Identity=35.3658536585366, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21356579, Length=244, Percent_Identity=28.6885245901639, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19920494, Length=185, Percent_Identity=30.2702702702703, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355201, Length=220, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 50440; Mature: 50440

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSEIVSMLARILAEHYRSGVSLKESFYRALDNPFSIPSHRARAIHRRLMELGKRLGLC
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHH
EEILDDVIQSGSFEDLGPELKGVLVTAADEMLFEGTSPALVTDAATRVAKELVSDRVADF
HHHHHHHHHCCCCHHCCCHHHHEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
VHAVCFDLEKYDVDRLKRRGYDDLCLRHYFPPDFVDYVRRVLPEDEIEDFLRACNKPAVK
HHHHHHHHHHHCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEE
YVRVNTLRADVDEVRERLAEEGVLTEPDEHIPDLLRVVEEEIPIVRTEAWKEGLVFTQDK
EEEHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEHHHHHCCCEEECCH
ASAAVAHVLDPQPGEFVVDLCAAPGGKTLHALCLMEGEGEILAVDKSDWRLDAMREKLAW
HHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCCEEEECCCCCHHHHHHHHHHH
QRVPDGVVELRCADAREIPEELDEEADRAIVDPPCSGMGSVQKRPETRWNVTKKRVRRYA
HHCCCHHHEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHH
KLQSELLEAAIKTVRPGGIVVYSTCTLTINENENVIRRVARRYDVTIEKVNLQFGRRGLV
HHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHCCCCEEEEHHHCCCCCC
PGTRRFYPHTDRCQGFFIAKLRKN
CCCCCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MKVSEIVSMLARILAEHYRSGVSLKESFYRALDNPFSIPSHRARAIHRRLMELGKRLGLC
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHH
EEILDDVIQSGSFEDLGPELKGVLVTAADEMLFEGTSPALVTDAATRVAKELVSDRVADF
HHHHHHHHHCCCCHHCCCHHHHEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
VHAVCFDLEKYDVDRLKRRGYDDLCLRHYFPPDFVDYVRRVLPEDEIEDFLRACNKPAVK
HHHHHHHHHHHCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEE
YVRVNTLRADVDEVRERLAEEGVLTEPDEHIPDLLRVVEEEIPIVRTEAWKEGLVFTQDK
EEEHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEHHHHHCCCEEECCH
ASAAVAHVLDPQPGEFVVDLCAAPGGKTLHALCLMEGEGEILAVDKSDWRLDAMREKLAW
HHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCCEEEECCCCCHHHHHHHHHHH
QRVPDGVVELRCADAREIPEELDEEADRAIVDPPCSGMGSVQKRPETRWNVTKKRVRRYA
HHCCCHHHEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHH
KLQSELLEAAIKTVRPGGIVVYSTCTLTINENENVIRRVARRYDVTIEKVNLQFGRRGLV
HHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHCCCCEEEEHHHCCCCCC
PGTRRFYPHTDRCQGFFIAKLRKN
CCCCCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]