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The map label for this gene is yqfA [C]

Identifier: 197120268

GI number: 197120268

Start: 4444001

End: 4444645

Strand: Direct

Name: yqfA [C]

Synonym: Gbem_3907

Alternate gene names: 197120268

Gene position: 4444001-4444645 (Clockwise)

Preceding gene: 197120266

Following gene: 197120288

Centisome position: 96.29

GC content: 58.29

Gene sequence:

>645_bases
ATGGAGATAATCAAGCGTCAGCAGTCAGCAGAGGAAGAAATTGCCAACAGCATCAGCCATGCCGTCGGATTGATCGCGGC
CATTGCCGCGACCCCGCCGCTTCTGTCCAAGGCTTTCAGCTATGGAGAGACCGGGTACGCCGTCGGTACCGCCATATATG
CAGCAACAATGGTTCTGCTCTACCTTGCCTCCTCCGTCTACCACGCCATGCCTCCGGGGAAACTGAAGGAGTTGTTCAAG
ACCATAGAACACTCGGCGATCTATCTGCTGATAGCCGGGACCTACACACCCTTTTCGCTTGGTGCGCTGCGTGGCCCTTG
GGGATGGACTCTTCTGTTTCTGGTTTGGACTTTCGCCACCGTCGGGGTCGTCTGGAAGTTCTGTCAAAAGATGCCGCGCC
CGATAGCGTCCACTATCCTCTATCTGGCCATGGGCTGGCTCATCATCGTCGCAGCGAAACCGTTGTTCACGCGTGTGCCG
CTGGCCGGCCTCCTGTGGATAGCGGCCGGCGGCGCGGCATACACCTTAGGCGTCGTTTTCTTCGCCTACGATTCCCGGCT
GCGCTTCGGCCATTTCATCTGGCACCTGTTCGTAATGGCAGGCACGGCCTGCCACTTCTGCGCCATAGTCTGGTACGCCT
TGTGA

Upstream 100 bases:

>100_bases
TAGTCCAACTGACGTGACAATTGATTCTCGCACAACTTGGCCGCAATGCAGCAACTCTCTACGCCGGCAGCGGGCTGCAG
ATGGTGAGGAAGTAATTTCG

Downstream 100 bases:

>100_bases
CCCGCGGCTTCAGGGTGCCGTTTTGCCCTTGCATGTTCGGCTGAAGATTCCCACCTCCGTTTGAAATCCGATGCAGTTAC
GGCGTCATGAGAGCTGTTCC

Product: hemolysin III family channel protein

Products: NA

Alternate protein names: Hemolysin III; Hly-III [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MEIIKRQQSAEEEIANSISHAVGLIAAIAATPPLLSKAFSYGETGYAVGTAIYAATMVLLYLASSVYHAMPPGKLKELFK
TIEHSAIYLLIAGTYTPFSLGALRGPWGWTLLFLVWTFATVGVVWKFCQKMPRPIASTILYLAMGWLIIVAAKPLFTRVP
LAGLLWIAAGGAAYTLGVVFFAYDSRLRFGHFIWHLFVMAGTACHFCAIVWYAL

Sequences:

>Translated_214_residues
MEIIKRQQSAEEEIANSISHAVGLIAAIAATPPLLSKAFSYGETGYAVGTAIYAATMVLLYLASSVYHAMPPGKLKELFK
TIEHSAIYLLIAGTYTPFSLGALRGPWGWTLLFLVWTFATVGVVWKFCQKMPRPIASTILYLAMGWLIIVAAKPLFTRVP
LAGLLWIAAGGAAYTLGVVFFAYDSRLRFGHFIWHLFVMAGTACHFCAIVWYAL
>Mature_214_residues
MEIIKRQQSAEEEIANSISHAVGLIAAIAATPPLLSKAFSYGETGYAVGTAIYAATMVLLYLASSVYHAMPPGKLKELFK
TIEHSAIYLLIAGTYTPFSLGALRGPWGWTLLFLVWTFATVGVVWKFCQKMPRPIASTILYLAMGWLIIVAAKPLFTRVP
LAGLLWIAAGGAAYTLGVVFFAYDSRLRFGHFIWHLFVMAGTACHFCAIVWYAL

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=213, Percent_Identity=30.0469483568075, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI154759277, Length=237, Percent_Identity=29.1139240506329, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI52630445, Length=213, Percent_Identity=27.6995305164319, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1789266, Length=211, Percent_Identity=40.2843601895735, Blast_Score=158, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71996356, Length=225, Percent_Identity=32.4444444444444, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24640324, Length=232, Percent_Identity=27.1551724137931, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 23458; Mature: 23458

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIKRQQSAEEEIANSISHAVGLIAAIAATPPLLSKAFSYGETGYAVGTAIYAATMVLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YLASSVYHAMPPGKLKELFKTIEHSAIYLLIAGTYTPFSLGALRGPWGWTLLFLVWTFAT
HHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHH
VGVVWKFCQKMPRPIASTILYLAMGWLIIVAAKPLFTRVPLAGLLWIAAGGAAYTLGVVF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHCCCHHHHHHHHH
FAYDSRLRFGHFIWHLFVMAGTACHFCAIVWYAL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MEIIKRQQSAEEEIANSISHAVGLIAAIAATPPLLSKAFSYGETGYAVGTAIYAATMVLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YLASSVYHAMPPGKLKELFKTIEHSAIYLLIAGTYTPFSLGALRGPWGWTLLFLVWTFAT
HHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHH
VGVVWKFCQKMPRPIASTILYLAMGWLIIVAAKPLFTRVPLAGLLWIAAGGAAYTLGVVF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHCCCHHHHHHHHH
FAYDSRLRFGHFIWHLFVMAGTACHFCAIVWYAL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855 [H]