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The map label for this gene is lldR [H]

Identifier: 197119276

GI number: 197119276

Start: 3350707

End: 3351429

Strand: Reverse

Name: lldR [H]

Synonym: Gbem_2904

Alternate gene names: 197119276

Gene position: 3351429-3350707 (Counterclockwise)

Preceding gene: 197119277

Following gene: 197119275

Centisome position: 72.62

GC content: 62.66

Gene sequence:

>723_bases
ATGAAATTTACGCCGATAAAACCGAAAAAAGTATCGACCCAGATCGCGGAGCAGATCCGCAGTTCCATACTGGCCGGCGA
GTTCAACCCGGGGGAGAAGCTTCCCCCCGAGCGCGAGCTTGCCGAGCTTTTCGGCGTCTCCCGTCCTTCGGTGCGCGAGG
CGCTCAACATCCTTACCTCCTCCGGACTCGTCGAGACCTATCAAGGGGGGGGCACGCTGGTCCGTTCCCTGGTGGAGAAC
TCCGCCGGGATGCCGCTCTCCGAGCTGATCCGCATTGACGGCGACCGTGCCCTCGACGTGATCGAAGTGCGCAAGGGGAT
GGAGTCCTGGACCGCCTGGTACGCCGCTACCCGGGCGCTCCCCGAGGACGTTCGGCGCCTGCAGGTTGTTGTCGACGGCA
TGGCCAAAAACCTGGAGCAGCTGAAGGCTTCGGAGGATTTCGACGCCCACTTCCACATGCTGGTCGCCCGCGCCACCCAC
AACGTGGTCTGGGGCCACATGATGCAGAGCATTTTCGAGGCGATGCAGGAGTTCCAGCGCGACGTCTGGCGCGCCGTTTA
TATGACGGAGGAGGACCAGCGCCTGCTCTTCAGCCACCACCTGAAGATCTATGAGATGATCAGGGACCGCGACGCCGACG
GCGCGAGAGTGGCCATGCTCGAGCACCTGGACTTCGCGCAGAAGAGATGCTCCGCCTACGTCTCCATGCGCGGCACCGAA
TAA

Upstream 100 bases:

>100_bases
CTTCATGCCGTATACGGAATTTTCCCGGCTGCCAGATTGGTCAAAAATATTTACCAGAAAACCTATTGCCTTCCTCTTAC
ATATGTAGTATCGGTGCCTT

Downstream 100 bases:

>100_bases
CGCGGCACCAAACTACCGATAAAGGCCCGGCAGCGATTCCTGCCGGGCCTTTGTGTTTTACGGCCGGCGACAATCTCCCG
CGGCGCCCAAATCCCCCGTT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKFTPIKPKKVSTQIAEQIRSSILAGEFNPGEKLPPERELAELFGVSRPSVREALNILTSSGLVETYQGGGTLVRSLVEN
SAGMPLSELIRIDGDRALDVIEVRKGMESWTAWYAATRALPEDVRRLQVVVDGMAKNLEQLKASEDFDAHFHMLVARATH
NVVWGHMMQSIFEAMQEFQRDVWRAVYMTEEDQRLLFSHHLKIYEMIRDRDADGARVAMLEHLDFAQKRCSAYVSMRGTE

Sequences:

>Translated_240_residues
MKFTPIKPKKVSTQIAEQIRSSILAGEFNPGEKLPPERELAELFGVSRPSVREALNILTSSGLVETYQGGGTLVRSLVEN
SAGMPLSELIRIDGDRALDVIEVRKGMESWTAWYAATRALPEDVRRLQVVVDGMAKNLEQLKASEDFDAHFHMLVARATH
NVVWGHMMQSIFEAMQEFQRDVWRAVYMTEEDQRLLFSHHLKIYEMIRDRDADGARVAMLEHLDFAQKRCSAYVSMRGTE
>Mature_240_residues
MKFTPIKPKKVSTQIAEQIRSSILAGEFNPGEKLPPERELAELFGVSRPSVREALNILTSSGLVETYQGGGTLVRSLVEN
SAGMPLSELIRIDGDRALDVIEVRKGMESWTAWYAATRALPEDVRRLQVVVDGMAKNLEQLKASEDFDAHFHMLVARATH
NVVWGHMMQSIFEAMQEFQRDVWRAVYMTEEDQRLLFSHHLKIYEMIRDRDADGARVAMLEHLDFAQKRCSAYVSMRGTE

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=224, Percent_Identity=34.375, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1786303, Length=234, Percent_Identity=35.8974358974359, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1790780, Length=227, Percent_Identity=29.9559471365639, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789353, Length=225, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789621, Length=235, Percent_Identity=30.2127659574468, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994955, Length=212, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI87082208, Length=221, Percent_Identity=26.6968325791855, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27297; Mature: 27297

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTPIKPKKVSTQIAEQIRSSILAGEFNPGEKLPPERELAELFGVSRPSVREALNILTS
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
SGLVETYQGGGTLVRSLVENSAGMPLSELIRIDGDRALDVIEVRKGMESWTAWYAATRAL
CCCHHHHCCHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PEDVRRLQVVVDGMAKNLEQLKASEDFDAHFHMLVARATHNVVWGHMMQSIFEAMQEFQR
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVWRAVYMTEEDQRLLFSHHLKIYEMIRDRDADGARVAMLEHLDFAQKRCSAYVSMRGTE
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFTPIKPKKVSTQIAEQIRSSILAGEFNPGEKLPPERELAELFGVSRPSVREALNILTS
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
SGLVETYQGGGTLVRSLVENSAGMPLSELIRIDGDRALDVIEVRKGMESWTAWYAATRAL
CCCHHHHCCHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PEDVRRLQVVVDGMAKNLEQLKASEDFDAHFHMLVARATHNVVWGHMMQSIFEAMQEFQR
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVWRAVYMTEEDQRLLFSHHLKIYEMIRDRDADGARVAMLEHLDFAQKRCSAYVSMRGTE
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]