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The map label for this gene is hflX [H]

Identifier: 197119188

GI number: 197119188

Start: 3242015

End: 3243688

Strand: Direct

Name: hflX [H]

Synonym: Gbem_2815

Alternate gene names: 197119188

Gene position: 3242015-3243688 (Clockwise)

Preceding gene: 197119187

Following gene: 197119189

Centisome position: 70.25

GC content: 63.92

Gene sequence:

>1674_bases
TTGAAGTCGAGCCAGGTAAAGCGGCTCGAAAGGCTGTACCGCCGCCGTGTGAAACCGGGCGAGGTGATCTCGCTGGAACT
GGCCCGGGAAATGGCCGACATCTCCCTGGAGATCAGGCGCCAGCTCGGCATCCTGGTAAGCCGCATCGGCGAGATCGCTT
ACGTGGTCGTAGGCGACGAGCGCGCCCTGATGATCCCGGCCCTGGAGGATTACCCCCTGGGACGCAGGCTTTTGCGCGGC
ATCCGCCTGGTGCACACCCACCTGAAGGGGGAGCCGCTCTCCGACGACGACTTGACCGACCTCTCGCTTTTGCGCCTCGA
CATGGTCGCGGCCCTGCAACTCACCCAGAACCCTGACCGCTTCTCGATCCAGACCGCAGAGCTCGTCCCACCGGAGGGGC
ACAACCTCCCCTACCAGGTGGAGCCCTCCGTCCCCTTCGCCAAGTTCGACCTCGACTTCCGCTCCTTCGTCGAGACCCTG
GAGCAGACCCTTGAGCGCGGCCTCAAGGAGGGGACCCTGGTCGCAACCGGCCAGGAGCGCGGCATCCTCATCTCGGTGAC
CCAGCGCCCGATGGAAGAGGCGGTCGACTCCATGGAAGAACTGAAGGAGCTGGCGAGAACCGCCGGGGTCGGCGTACTGG
ACACCGTGATCCAGCGCCCGAAGGAGTTCAACCCCCGCTACCTTTTGGGGGAAGGGAAGATCCGCGAGGTGCTCATCAAG
GCGCTGCAGTTCGGTGCTACCATGTTGGTTTTCGACCAGGAGCTCTCCCCCGCCCAGGTCCGCTCCATCTCGGAGCTGAC
CGAACTGAAGGTCATCGACCGCAGCCAGCTGATCCTGGACATCTTCGCCCGGCGCGCCACCTCGCAGGACGGCAAGGTGC
AGGTGGAGCTCGCCCAGTTGAAGTACCTCCTCCCCAGGCTGATCGGCCGCGGGGTGCAGATGTCGCGGCTCATGGGGGGG
ATCGGCGGGCGCGGGCCCGGCGAGACCAAGCTCGAAGTCGACCGCAGGCGCATCAGGGACCGCATCGCCCACCTGGAACG
GGAGCTGAAGGAGCTTTCCAACGGCCGCTATCAGCGCCGCCAGAAAAGGGTGAAGGCGGGAATCCCCATCATCTCCATCG
TCGGCTACACCAACGCCGGTAAATCGACGCTCTTGAACACACTCACCCGCAGCGAAGTTTTCACCGAGGACCTCCTCTTT
GCCACTCTCGACACCTCGTCGCGCCGGCTGCGCTTTCCCATGGACCGAGAGGTGATCATAACCGACACCGTGGGCTTCAT
CCGCAGCCTCCCCAAGTCGCTTCTGGGTGCGTTCAAGGCGACGCTGGAGGAGCTGAAAGACGCCGATCTCTTGATCCACC
TGGTCGACTGCAGCAACCCCCGCTTCGAGGAGCAGATCATCCAGGTGGATGCCATCCTGGGCGAACTGGAGCTCTCGCAA
AAACCCAAGCTTCTGGTCTTCAACAAGGCGGACCTCCTTCCCGAACTGAAGAAGGGGGACCCGCTCGCGTTCATGAAAGT
ACGCCAGCTAACCCGCAGGTACGGGGCCGTCACCATCAGCGCCGCCGACCGCAAAACCCTGGAGCCGCTCCTGAAGGAGC
TGCAGCACCGTTTCTGGCACGACGTCGAGGATTACCGCGCGCCCGGACAAAACCACGACGAGTTCGAGGAGTAG

Upstream 100 bases:

>100_bases
GGGTGAGCGGGGAGATCCACTTCGTCGACAGCGGCTACAACATCATCGGCCTGTAAACGGGAGGCGCGCCATCAAAGGAC
TGCACGGTAATCTGACAGGG

Downstream 100 bases:

>100_bases
CCAGCTTAGAAAAAGGCGCCGCATCCCTTCCTGCTTCCTGGCGCGATCCCCCTGCTCTTGCAGCAGGAGGCCTTCAACGG
CATCCCTCCCGAGACCGATC

Product: HflX subfamily GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MKSSQVKRLERLYRRRVKPGEVISLELAREMADISLEIRRQLGILVSRIGEIAYVVVGDERALMIPALEDYPLGRRLLRG
IRLVHTHLKGEPLSDDDLTDLSLLRLDMVAALQLTQNPDRFSIQTAELVPPEGHNLPYQVEPSVPFAKFDLDFRSFVETL
EQTLERGLKEGTLVATGQERGILISVTQRPMEEAVDSMEELKELARTAGVGVLDTVIQRPKEFNPRYLLGEGKIREVLIK
ALQFGATMLVFDQELSPAQVRSISELTELKVIDRSQLILDIFARRATSQDGKVQVELAQLKYLLPRLIGRGVQMSRLMGG
IGGRGPGETKLEVDRRRIRDRIAHLERELKELSNGRYQRRQKRVKAGIPIISIVGYTNAGKSTLLNTLTRSEVFTEDLLF
ATLDTSSRRLRFPMDREVIITDTVGFIRSLPKSLLGAFKATLEELKDADLLIHLVDCSNPRFEEQIIQVDAILGELELSQ
KPKLLVFNKADLLPELKKGDPLAFMKVRQLTRRYGAVTISAADRKTLEPLLKELQHRFWHDVEDYRAPGQNHDEFEE

Sequences:

>Translated_557_residues
MKSSQVKRLERLYRRRVKPGEVISLELAREMADISLEIRRQLGILVSRIGEIAYVVVGDERALMIPALEDYPLGRRLLRG
IRLVHTHLKGEPLSDDDLTDLSLLRLDMVAALQLTQNPDRFSIQTAELVPPEGHNLPYQVEPSVPFAKFDLDFRSFVETL
EQTLERGLKEGTLVATGQERGILISVTQRPMEEAVDSMEELKELARTAGVGVLDTVIQRPKEFNPRYLLGEGKIREVLIK
ALQFGATMLVFDQELSPAQVRSISELTELKVIDRSQLILDIFARRATSQDGKVQVELAQLKYLLPRLIGRGVQMSRLMGG
IGGRGPGETKLEVDRRRIRDRIAHLERELKELSNGRYQRRQKRVKAGIPIISIVGYTNAGKSTLLNTLTRSEVFTEDLLF
ATLDTSSRRLRFPMDREVIITDTVGFIRSLPKSLLGAFKATLEELKDADLLIHLVDCSNPRFEEQIIQVDAILGELELSQ
KPKLLVFNKADLLPELKKGDPLAFMKVRQLTRRYGAVTISAADRKTLEPLLKELQHRFWHDVEDYRAPGQNHDEFEE
>Mature_557_residues
MKSSQVKRLERLYRRRVKPGEVISLELAREMADISLEIRRQLGILVSRIGEIAYVVVGDERALMIPALEDYPLGRRLLRG
IRLVHTHLKGEPLSDDDLTDLSLLRLDMVAALQLTQNPDRFSIQTAELVPPEGHNLPYQVEPSVPFAKFDLDFRSFVETL
EQTLERGLKEGTLVATGQERGILISVTQRPMEEAVDSMEELKELARTAGVGVLDTVIQRPKEFNPRYLLGEGKIREVLIK
ALQFGATMLVFDQELSPAQVRSISELTELKVIDRSQLILDIFARRATSQDGKVQVELAQLKYLLPRLIGRGVQMSRLMGG
IGGRGPGETKLEVDRRRIRDRIAHLERELKELSNGRYQRRQKRVKAGIPIISIVGYTNAGKSTLLNTLTRSEVFTEDLLF
ATLDTSSRRLRFPMDREVIITDTVGFIRSLPKSLLGAFKATLEELKDADLLIHLVDCSNPRFEEQIIQVDAILGELELSQ
KPKLLVFNKADLLPELKKGDPLAFMKVRQLTRRYGAVTISAADRKTLEPLLKELQHRFWHDVEDYRAPGQNHDEFEE

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=195, Percent_Identity=34.8717948717949, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI310124269, Length=181, Percent_Identity=35.9116022099448, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310124267, Length=181, Percent_Identity=35.9116022099448, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310124171, Length=181, Percent_Identity=35.9116022099448, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310124169, Length=181, Percent_Identity=35.9116022099448, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310133118, Length=195, Percent_Identity=34.8717948717949, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1790615, Length=321, Percent_Identity=44.8598130841121, Blast_Score=278, Evalue=9e-76,
Organism=Caenorhabditis elegans, GI17561038, Length=297, Percent_Identity=28.6195286195286, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24650079, Length=331, Percent_Identity=32.6283987915408, Blast_Score=126, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 63273; Mature: 63273

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSQVKRLERLYRRRVKPGEVISLELAREMADISLEIRRQLGILVSRIGEIAYVVVGDE
CCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
RALMIPALEDYPLGRRLLRGIRLVHTHLKGEPLSDDDLTDLSLLRLDMVAALQLTQNPDR
CEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FSIQTAELVPPEGHNLPYQVEPSVPFAKFDLDFRSFVETLEQTLERGLKEGTLVATGQER
EEEEEEECCCCCCCCCCEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCEEEECCCC
GILISVTQRPMEEAVDSMEELKELARTAGVGVLDTVIQRPKEFNPRYLLGEGKIREVLIK
CEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEECCCHHHHHHHH
ALQFGATMLVFDQELSPAQVRSISELTELKVIDRSQLILDIFARRATSQDGKVQVELAQL
HHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
KYLLPRLIGRGVQMSRLMGGIGGRGPGETKLEVDRRRIRDRIAHLERELKELSNGRYQRR
HHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QKRVKAGIPIISIVGYTNAGKSTLLNTLTRSEVFTEDLLFATLDTSSRRLRFPMDREVII
HHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCEEE
TDTVGFIRSLPKSLLGAFKATLEELKDADLLIHLVDCSNPRFEEQIIQVDAILGELELSQ
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
KPKLLVFNKADLLPELKKGDPLAFMKVRQLTRRYGAVTISAADRKTLEPLLKELQHRFWH
CCCEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHCC
DVEDYRAPGQNHDEFEE
CHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKSSQVKRLERLYRRRVKPGEVISLELAREMADISLEIRRQLGILVSRIGEIAYVVVGDE
CCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
RALMIPALEDYPLGRRLLRGIRLVHTHLKGEPLSDDDLTDLSLLRLDMVAALQLTQNPDR
CEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FSIQTAELVPPEGHNLPYQVEPSVPFAKFDLDFRSFVETLEQTLERGLKEGTLVATGQER
EEEEEEECCCCCCCCCCEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCEEEECCCC
GILISVTQRPMEEAVDSMEELKELARTAGVGVLDTVIQRPKEFNPRYLLGEGKIREVLIK
CEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEECCCHHHHHHHH
ALQFGATMLVFDQELSPAQVRSISELTELKVIDRSQLILDIFARRATSQDGKVQVELAQL
HHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
KYLLPRLIGRGVQMSRLMGGIGGRGPGETKLEVDRRRIRDRIAHLERELKELSNGRYQRR
HHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QKRVKAGIPIISIVGYTNAGKSTLLNTLTRSEVFTEDLLFATLDTSSRRLRFPMDREVII
HHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCEEE
TDTVGFIRSLPKSLLGAFKATLEELKDADLLIHLVDCSNPRFEEQIIQVDAILGELELSQ
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
KPKLLVFNKADLLPELKKGDPLAFMKVRQLTRRYGAVTISAADRKTLEPLLKELQHRFWH
CCCEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHCC
DVEDYRAPGQNHDEFEE
CHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]