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The map label for this gene is yaeL [C]

Identifier: 197119122

GI number: 197119122

Start: 3179056

End: 3180120

Strand: Reverse

Name: yaeL [C]

Synonym: Gbem_2749

Alternate gene names: 197119122

Gene position: 3180120-3179056 (Counterclockwise)

Preceding gene: 197119123

Following gene: 197119121

Centisome position: 68.91

GC content: 63.66

Gene sequence:

>1065_bases
ATGAGCATACTTTTCGCAATCATCGCCCTCGGGGCTCTGATTTTCTTCCATGAGCTCGGACACTTCCTCTTCGCCAAGGC
TTTCGGGGTCGGGGTGGAGAAATTCTCTCTCGGCTTCGGCCCCAAGATCTACGGCAGGAAAATAGGCGAGACCGAGTACC
TCCTGTCGGCGCTCCCCTTGGGGGGATACGTGAAGATGGTGGGGGAGGGGGAGGACGTCGAGATCTCCGAAGAGGACCGC
GCCCGCTCCTTCGCCGAGAAGCCGGTGCTGCAGCGGATCGTGATCGTCGCGGCCGGGCCCATCTTCAACCTCCTCTTCGC
CTACATCCTTTTCATCATCATCTTCATGGTTGGGGTCCCCGCCGTCACCACCAAGGTGGGGGACGTCGTTGCCGATAAAC
CCGCCGCCAAGGCAGGCGTGAAGGCCGGCGACACCATCCGCTCCGTGAACGGCAAGCCCGTGGCGCGCTGGGACGACTTC
GCGAAGATCATCGCCGAGGGGAAGCTCGCGCCGGTCGAGGTAGAGGTGCAGCGGGGGCAGACCCCCCTGAAATTCACCAT
GGTCCCGGAGAGCCGCACCAGCAAGAACCTCTTGGGGGACACGGTGACCCAGCCGGTGATAGGCGTGGTTGCAGCCGGCG
AGACCGTGATTGACCATTTCCCCCCGGGCGAGGCGATAACGAGGGGGAGCGCCCAGTGCTGGAACGTGATCAGGCTCACC
GTGCTCTCGCTGGTGCGCCTGGTCGAGCGCGCCATCCCGCTGGACAACATCGGCGGCCCGATCATGATCGTGAAGATGGC
GGGGGAACAGGCGGCAGCCGGCGGGGTGAGCTTCCTCGCTTTCGTGGCGCTCTTGTCGGTGAACCTGGGCGTCCTGAACC
TTTTGCCGGTGCCGATTCTCGATGGCGGGCACCTGGCGTTTTTCCTGATCGAACTGGTGACGGGGAGACCGCTCAGCAAG
AGGGCCCGGGAGATCGCCCAGCAGGTTGGGCTCGTGCTCCTGATCGGCCTCATGATGCTCGCCTTCTACAACGACATCGC
CCGCATGTTCGCCCAAAAGGCGTGA

Upstream 100 bases:

>100_bases
GCTGAAACAAAGGCTTTTCTTCGGGTGCAATAGGGCACGCGAAGGCACCAGCTTTCCGGTGCGGTCCGGTTGCCGGCCGC
GGTCCGGTTGAGGAAACGTT

Downstream 100 bases:

>100_bases
CGGCAGAGGAAAACGACGTGAAGATACTCACCATCGACACCTCCAGCAACTGCTCCTCCGTCTCCTTGAGCGACGGCTCC
ACCCTTCTGGGCGAGTGCAT

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSILFAIIALGALIFFHELGHFLFAKAFGVGVEKFSLGFGPKIYGRKIGETEYLLSALPLGGYVKMVGEGEDVEISEEDR
ARSFAEKPVLQRIVIVAAGPIFNLLFAYILFIIIFMVGVPAVTTKVGDVVADKPAAKAGVKAGDTIRSVNGKPVARWDDF
AKIIAEGKLAPVEVEVQRGQTPLKFTMVPESRTSKNLLGDTVTQPVIGVVAAGETVIDHFPPGEAITRGSAQCWNVIRLT
VLSLVRLVERAIPLDNIGGPIMIVKMAGEQAAAGGVSFLAFVALLSVNLGVLNLLPVPILDGGHLAFFLIELVTGRPLSK
RAREIAQQVGLVLLIGLMMLAFYNDIARMFAQKA

Sequences:

>Translated_354_residues
MSILFAIIALGALIFFHELGHFLFAKAFGVGVEKFSLGFGPKIYGRKIGETEYLLSALPLGGYVKMVGEGEDVEISEEDR
ARSFAEKPVLQRIVIVAAGPIFNLLFAYILFIIIFMVGVPAVTTKVGDVVADKPAAKAGVKAGDTIRSVNGKPVARWDDF
AKIIAEGKLAPVEVEVQRGQTPLKFTMVPESRTSKNLLGDTVTQPVIGVVAAGETVIDHFPPGEAITRGSAQCWNVIRLT
VLSLVRLVERAIPLDNIGGPIMIVKMAGEQAAAGGVSFLAFVALLSVNLGVLNLLPVPILDGGHLAFFLIELVTGRPLSK
RAREIAQQVGLVLLIGLMMLAFYNDIARMFAQKA
>Mature_353_residues
SILFAIIALGALIFFHELGHFLFAKAFGVGVEKFSLGFGPKIYGRKIGETEYLLSALPLGGYVKMVGEGEDVEISEEDRA
RSFAEKPVLQRIVIVAAGPIFNLLFAYILFIIIFMVGVPAVTTKVGDVVADKPAAKAGVKAGDTIRSVNGKPVARWDDFA
KIIAEGKLAPVEVEVQRGQTPLKFTMVPESRTSKNLLGDTVTQPVIGVVAAGETVIDHFPPGEAITRGSAQCWNVIRLTV
LSLVRLVERAIPLDNIGGPIMIVKMAGEQAAAGGVSFLAFVALLSVNLGVLNLLPVPILDGGHLAFFLIELVTGRPLSKR
AREIAQQVGLVLLIGLMMLAFYNDIARMFAQKA

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=231, Percent_Identity=35.9307359307359, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 37920; Mature: 37789

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILFAIIALGALIFFHELGHFLFAKAFGVGVEKFSLGFGPKIYGRKIGETEYLLSALPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHCCCCCCHHHHHHHCCC
GGYVKMVGEGEDVEISEEDRARSFAEKPVLQRIVIVAAGPIFNLLFAYILFIIIFMVGVP
CCEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
AVTTKVGDVVADKPAAKAGVKAGDTIRSVNGKPVARWDDFAKIIAEGKLAPVEVEVQRGQ
HHHHHHHHHHCCCCHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCC
TPLKFTMVPESRTSKNLLGDTVTQPVIGVVAAGETVIDHFPPGEAITRGSAQCWNVIRLT
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHCCCHHHHHHHHHH
VLSLVRLVERAIPLDNIGGPIMIVKMAGEQAAAGGVSFLAFVALLSVNLGVLNLLPVPIL
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHCHHHHHHHHHHHHHCCCHHHHCCCCCC
DGGHLAFFLIELVTGRPLSKRAREIAQQVGLVLLIGLMMLAFYNDIARMFAQKA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SILFAIIALGALIFFHELGHFLFAKAFGVGVEKFSLGFGPKIYGRKIGETEYLLSALPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHCCCCCCHHHHHHHCCC
GGYVKMVGEGEDVEISEEDRARSFAEKPVLQRIVIVAAGPIFNLLFAYILFIIIFMVGVP
CCEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
AVTTKVGDVVADKPAAKAGVKAGDTIRSVNGKPVARWDDFAKIIAEGKLAPVEVEVQRGQ
HHHHHHHHHHCCCCHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCC
TPLKFTMVPESRTSKNLLGDTVTQPVIGVVAAGETVIDHFPPGEAITRGSAQCWNVIRLT
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHCCCHHHHHHHHHH
VLSLVRLVERAIPLDNIGGPIMIVKMAGEQAAAGGVSFLAFVALLSVNLGVLNLLPVPIL
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHCHHHHHHHHHHHHHCCCHHHHCCCCCC
DGGHLAFFLIELVTGRPLSKRAREIAQQVGLVLLIGLMMLAFYNDIARMFAQKA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]