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The map label for this gene is pilC [H]

Identifier: 197118970

GI number: 197118970

Start: 3003038

End: 3004261

Strand: Reverse

Name: pilC [H]

Synonym: Gbem_2593

Alternate gene names: 197118970

Gene position: 3004261-3003038 (Counterclockwise)

Preceding gene: 197118971

Following gene: 197118969

Centisome position: 65.1

GC content: 60.62

Gene sequence:

>1224_bases
ATGCCTAAGTTTGATTGGGAAGCAAGGAGCAAGGCCGGAAGCACCCAGAAAGGGGTGATGGAGGCCGGAAACGCGGCCCA
GGTCGAGTCCCAGCTTAAAAGATACGGATTTTCCGGCATCACGGTGAAGGAACAGGGGAAAGGGCTGAGCATGCAGCTCA
AGTTCCCGGGCTCCGGCGCGAAGAAGATCGAGACCAAGGACCTCGTGGTATTTACGCGCCAGTTCGCCACCATGATCGAC
TCCGGCCTCCCCCTGGTGCAGTGCCTGGACATCCTGTCGGGACAGCAGGAGAACAAGACCTTCAAGGAGATCCTGGTCAA
GGTGAAGGAAAGCGTGGAGAGCGGCTCCACCTTCGCCGACGCCCTCGCGAAGCACCCGAAGGCCTTCGACCAGCTCTACG
TCAACCTGGTAGCTGCAGGCGAGGTCGGCGGTATCCTCGACACCATCTTGGCCAGGCTCGCAGCCTACATCGAGAAGGCG
ATGAAGCTGAAGAAGCAGGTTAAGGGTGCCATGGTGTACCCGATCACCATCATGTCCATCGCGGTCGTCGTCGTCGGCGT
CATCCTGGTCTTCGTCATCCCCACTTTTGCCAAGATGTTCGCCGACTTTGGCGGCGAGCTTCCGATGCCGACCAAGATTG
TCATAGCCATGTCCAACTTCCTGACCAAGTACCTGGTGGTCATTATCGCCATTCTCTTCGGCATCAAGTGGGCCATCGGC
AAGTACTACCAGACCCCCGGCGGCAGGAAGAAGATCGACCGTTTCGCGCTGCAGGCGCCCATCGCCGGCCCCCTGATCCG
GAAGGTCTCAGTGGCTAAGTTCACCCGCACCCTGGGGACCATGATCAGCTCCGGCGTCCCCATCATGGACGGCCTGGAGA
TCGTGGCCAAGACGGCCGGCAACAAGATCGTCGAGGAGGCGATCTACAAGGTGCGCCAGTCCATCTCCGAAGGGAAAACC
ATCGCCGAACCTTTGGCCGAAAGCGGCGTCTTCCCTCCCATGGTGGTGCAGATGATCTCCGTCGGCGAGGCGACCGGCGC
CATGGACGCCATGCTCAACAAGATCGCCGACTTCTACGACGACGAGGTCGACGACGCGGTCGGCGCCATGACCTCCATGA
TGGAGCCGTTGTTGATGGTGTTCCTGGGAACCACGGTTGGCGGCCTGGTCGTCGCGATGTACCTGCCGATCTTCAAGCTT
GCCGGCGCGGTCGGCGGCGGTTGA

Upstream 100 bases:

>100_bases
AAGCAGATGCTCGCACCGGGTGCGGGTGCCGGACAGATGAGGCGCCCCCCCCAGAGGTAAGGTTAGCCGGTCCCTTGGCG
GGGCTGCAAAGGAGTAAGTA

Downstream 100 bases:

>100_bases
TTGGATGATCGACAGGAAAAGGGTTTTTTGGTTCATACTGCTTAGGTTGTTGGTGGTGTCCATTTTCCTGGCCACCACCA
CTTTCCTCGACGTACGTACC

Product: type IV pilus biogenesis protein PilC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MPKFDWEARSKAGSTQKGVMEAGNAAQVESQLKRYGFSGITVKEQGKGLSMQLKFPGSGAKKIETKDLVVFTRQFATMID
SGLPLVQCLDILSGQQENKTFKEILVKVKESVESGSTFADALAKHPKAFDQLYVNLVAAGEVGGILDTILARLAAYIEKA
MKLKKQVKGAMVYPITIMSIAVVVVGVILVFVIPTFAKMFADFGGELPMPTKIVIAMSNFLTKYLVVIIAILFGIKWAIG
KYYQTPGGRKKIDRFALQAPIAGPLIRKVSVAKFTRTLGTMISSGVPIMDGLEIVAKTAGNKIVEEAIYKVRQSISEGKT
IAEPLAESGVFPPMVVQMISVGEATGAMDAMLNKIADFYDDEVDDAVGAMTSMMEPLLMVFLGTTVGGLVVAMYLPIFKL
AGAVGGG

Sequences:

>Translated_407_residues
MPKFDWEARSKAGSTQKGVMEAGNAAQVESQLKRYGFSGITVKEQGKGLSMQLKFPGSGAKKIETKDLVVFTRQFATMID
SGLPLVQCLDILSGQQENKTFKEILVKVKESVESGSTFADALAKHPKAFDQLYVNLVAAGEVGGILDTILARLAAYIEKA
MKLKKQVKGAMVYPITIMSIAVVVVGVILVFVIPTFAKMFADFGGELPMPTKIVIAMSNFLTKYLVVIIAILFGIKWAIG
KYYQTPGGRKKIDRFALQAPIAGPLIRKVSVAKFTRTLGTMISSGVPIMDGLEIVAKTAGNKIVEEAIYKVRQSISEGKT
IAEPLAESGVFPPMVVQMISVGEATGAMDAMLNKIADFYDDEVDDAVGAMTSMMEPLLMVFLGTTVGGLVVAMYLPIFKL
AGAVGGG
>Mature_406_residues
PKFDWEARSKAGSTQKGVMEAGNAAQVESQLKRYGFSGITVKEQGKGLSMQLKFPGSGAKKIETKDLVVFTRQFATMIDS
GLPLVQCLDILSGQQENKTFKEILVKVKESVESGSTFADALAKHPKAFDQLYVNLVAAGEVGGILDTILARLAAYIEKAM
KLKKQVKGAMVYPITIMSIAVVVVGVILVFVIPTFAKMFADFGGELPMPTKIVIAMSNFLTKYLVVIIAILFGIKWAIGK
YYQTPGGRKKIDRFALQAPIAGPLIRKVSVAKFTRTLGTMISSGVPIMDGLEIVAKTAGNKIVEEAIYKVRQSISEGKTI
AEPLAESGVFPPMVVQMISVGEATGAMDAMLNKIADFYDDEVDDAVGAMTSMMEPLLMVFLGTTVGGLVVAMYLPIFKLA
GAVGGG

Specific function: Involved in the translocation of the type IV pilin [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=403, Percent_Identity=26.302729528536, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1786295, Length=336, Percent_Identity=30.3571428571429, Blast_Score=165, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 43645; Mature: 43514

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKFDWEARSKAGSTQKGVMEAGNAAQVESQLKRYGFSGITVKEQGKGLSMQLKFPGSGA
CCCCCCHHHCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCC
KKIETKDLVVFTRQFATMIDSGLPLVQCLDILSGQQENKTFKEILVKVKESVESGSTFAD
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHH
ALAKHPKAFDQLYVNLVAAGEVGGILDTILARLAAYIEKAMKLKKQVKGAMVYPITIMSI
HHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHH
AVVVVGVILVFVIPTFAKMFADFGGELPMPTKIVIAMSNFLTKYLVVIIAILFGIKWAIG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYYQTPGGRKKIDRFALQAPIAGPLIRKVSVAKFTRTLGTMISSGVPIMDGLEIVAKTAG
HHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
NKIVEEAIYKVRQSISEGKTIAEPLAESGVFPPMVVQMISVGEATGAMDAMLNKIADFYD
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DEVDDAVGAMTSMMEPLLMVFLGTTVGGLVVAMYLPIFKLAGAVGGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8820654 [H]