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The map label for this gene is htpG [H]

Identifier: 197118793

GI number: 197118793

Start: 2798659

End: 2800593

Strand: Direct

Name: htpG [H]

Synonym: Gbem_2414

Alternate gene names: 197118793

Gene position: 2798659-2800593 (Clockwise)

Preceding gene: 197118786

Following gene: 197118795

Centisome position: 60.64

GC content: 57.88

Gene sequence:

>1935_bases
ATGACCAAGACCGTCAAAAAGTTCGAGACCGAGGTTCAGCAACTCCTGGACCTGGTGATCCACTCCCTCTATTCCAACAA
GGAAATCTTCCTCCGGGAGCTGATCTCTAACGCTTCTGACGCCATTGACAAGATAAAGTTCGAATCCCATTCCAACATGG
AACTCCTGGAGGGGAACTCCGACTGGAAGATCAAGCTCCACGCGGACAAGGAAGCGGGAACCCTCACCGTCACCGACAAC
GGCATCGGCATGAGCATGGACGAGGTGGCTGAAAATATCGGCACCATCGCTAAATCCGGCACCAAGAGCTTCGTGGCGGC
ACTGAAGGAGCAGAACCTCGCCGACAACCCGGAGCTGATCGGGCAGTTTGGCGTCGGCTTCTACGCCTCTTTCATGGTGG
CCGACAAGGTCGTCCTTACCACCAGGAAAGCGGGCGGCAAGGAGTTCGGCTGCCGCTGGGAGTCGACCGGCGACGGCAGC
TACACCATCGAGGAGTGCGAAAAGGAGACCCGCGGCACCGAGATCGTCCTGCACCTCAAAGACGAAATGAAGGAGTTCCT
CGACGAGTGGAAGATCCGCTCCATCGTGAAGAAGTACTCCGACTACGTGCAGTACCCGGTAGTCATGGACATCACCCGCA
CCGAGCCGGTGAAGGACGCCGAAGGTAAGGTGATCGAGGGTGGCGGGACCATCGAGAAGACCACGGAGGAGACCCTCAAC
TCCATGAAGGCGATCTGGACCAGGTCCAAGAGCGAGATCACCGAGGAGGAGTACGACGAGTTCTACAAGCACATCTCCCA
CGACTACGACAAGCCGCTTTCCACCATCCATTACTCCGCCGAAGGGGTGAGCGAGTTCAAGGCAATCGTCTACATCCCTT
CGCACAAACCCTACGACCTCTTCCTGCGGGACCACAAGAAAGGGGTGCACCTCTACGTGAAGCGGGTCTATATCACCGAC
AACTGCGAGGCGCTGCTCCCCGACTACCTGCGCTTCATCAAGGGTGTGGTCGATTCCTCGGACCTGCCGCTCAACGTCTC
CCGCGAGATCCTGCAGGAGGACGTGCAGATCAAGCGGATCCAGAAGTCCCTGGTCGGCAAGATCCTCTCCACCCTGGCCG
AAATGAAGGAGAAGAACTTCGAGGAGTACCTGAAGTTCTATGCGGAATTCGGCCCGGTGCTCAAGGAAGGGATCCACTTC
GACCACGCCAACAAGGAGAAGATCCAGGACCTCCTCCTCTACGAGAGCTCCAAGACCGAGAAAGGGAAGTACGTCTCCTT
CAAGGAGTACGCGGAGCGCATGCCCGAGGGGCAGAAGGAGATCTACTTCATCACCGGCATGTCCCGCGAGGCGGTGGAGA
ATTCACCCTATATGGAGGCGCTGCGTAAGAAGGATTACGAAGTCCTCTACATGATCGACCCGGTCGACGAGTGGGTGGTG
CAGGCAATCACCGAGTACCAGGAGAAGCACCTGAAAGCGATCGACCGCGGCGACCTGGAGATAGACACCGAGGAGGAGAA
GAAGGAGAAGGAAGCGAAGAAGGAGGAGGCGAAGAAGGAATACGGGAGCCTCATGGAGTTTATCCAGGAGACCCTCAAGG
AGAAGGTGAAGGAAGTCCGCCTCTCCTCCCGCTTGACCGACAGCGCCTGCTGCCTGGTGGCCGACGAGATGGGGCTGAAC
GCCAACATGGAGAAGATCCTCAAGGCGATGAACCAGGAGGTCCCGGAAGCGAAGAGGATCCTGGAACTAAACCCGGACCA
CCAGATCCTGCAGGTCATGACGGCGATGTACGAAAAGGACAAGGCCGACCCGAAGCTCAAGGACTACAGCGAGCTCCTTT
TCGATCAGGCCCTCCTCACCGAGGGGTCCCCGATCAAGGACCCGCTCCGCTTCACCAAGCTGGTGAGCGAGTTGATGGTC
GTCGGCGGGAAATAA

Upstream 100 bases:

>100_bases
TATGTATTTCGGTTTTTCTTTCCTCCCCCCTTGAAATACGGAACTGCAGTGATTAGGTTCTGCGGGTCCAATTACTTTCC
CAAAGGAGATCACTACCACC

Downstream 100 bases:

>100_bases
GGGAAGATAAAAATAAGCCGGGGGGACACAAGGTCCCTCCGGCTTTGCCATATTCAGGGGCCTAGCCCCTTGGCTATAGA
GACGGACAGCCAGGCTTACA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 644; Mature: 643

Protein sequence:

>644_residues
MTKTVKKFETEVQQLLDLVIHSLYSNKEIFLRELISNASDAIDKIKFESHSNMELLEGNSDWKIKLHADKEAGTLTVTDN
GIGMSMDEVAENIGTIAKSGTKSFVAALKEQNLADNPELIGQFGVGFYASFMVADKVVLTTRKAGGKEFGCRWESTGDGS
YTIEECEKETRGTEIVLHLKDEMKEFLDEWKIRSIVKKYSDYVQYPVVMDITRTEPVKDAEGKVIEGGGTIEKTTEETLN
SMKAIWTRSKSEITEEEYDEFYKHISHDYDKPLSTIHYSAEGVSEFKAIVYIPSHKPYDLFLRDHKKGVHLYVKRVYITD
NCEALLPDYLRFIKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVGKILSTLAEMKEKNFEEYLKFYAEFGPVLKEGIHF
DHANKEKIQDLLLYESSKTEKGKYVSFKEYAERMPEGQKEIYFITGMSREAVENSPYMEALRKKDYEVLYMIDPVDEWVV
QAITEYQEKHLKAIDRGDLEIDTEEEKKEKEAKKEEAKKEYGSLMEFIQETLKEKVKEVRLSSRLTDSACCLVADEMGLN
ANMEKILKAMNQEVPEAKRILELNPDHQILQVMTAMYEKDKADPKLKDYSELLFDQALLTEGSPIKDPLRFTKLVSELMV
VGGK

Sequences:

>Translated_644_residues
MTKTVKKFETEVQQLLDLVIHSLYSNKEIFLRELISNASDAIDKIKFESHSNMELLEGNSDWKIKLHADKEAGTLTVTDN
GIGMSMDEVAENIGTIAKSGTKSFVAALKEQNLADNPELIGQFGVGFYASFMVADKVVLTTRKAGGKEFGCRWESTGDGS
YTIEECEKETRGTEIVLHLKDEMKEFLDEWKIRSIVKKYSDYVQYPVVMDITRTEPVKDAEGKVIEGGGTIEKTTEETLN
SMKAIWTRSKSEITEEEYDEFYKHISHDYDKPLSTIHYSAEGVSEFKAIVYIPSHKPYDLFLRDHKKGVHLYVKRVYITD
NCEALLPDYLRFIKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVGKILSTLAEMKEKNFEEYLKFYAEFGPVLKEGIHF
DHANKEKIQDLLLYESSKTEKGKYVSFKEYAERMPEGQKEIYFITGMSREAVENSPYMEALRKKDYEVLYMIDPVDEWVV
QAITEYQEKHLKAIDRGDLEIDTEEEKKEKEAKKEEAKKEYGSLMEFIQETLKEKVKEVRLSSRLTDSACCLVADEMGLN
ANMEKILKAMNQEVPEAKRILELNPDHQILQVMTAMYEKDKADPKLKDYSELLFDQALLTEGSPIKDPLRFTKLVSELMV
VGGK
>Mature_643_residues
TKTVKKFETEVQQLLDLVIHSLYSNKEIFLRELISNASDAIDKIKFESHSNMELLEGNSDWKIKLHADKEAGTLTVTDNG
IGMSMDEVAENIGTIAKSGTKSFVAALKEQNLADNPELIGQFGVGFYASFMVADKVVLTTRKAGGKEFGCRWESTGDGSY
TIEECEKETRGTEIVLHLKDEMKEFLDEWKIRSIVKKYSDYVQYPVVMDITRTEPVKDAEGKVIEGGGTIEKTTEETLNS
MKAIWTRSKSEITEEEYDEFYKHISHDYDKPLSTIHYSAEGVSEFKAIVYIPSHKPYDLFLRDHKKGVHLYVKRVYITDN
CEALLPDYLRFIKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVGKILSTLAEMKEKNFEEYLKFYAEFGPVLKEGIHFD
HANKEKIQDLLLYESSKTEKGKYVSFKEYAERMPEGQKEIYFITGMSREAVENSPYMEALRKKDYEVLYMIDPVDEWVVQ
AITEYQEKHLKAIDRGDLEIDTEEEKKEKEAKKEEAKKEYGSLMEFIQETLKEKVKEVRLSSRLTDSACCLVADEMGLNA
NMEKILKAMNQEVPEAKRILELNPDHQILQVMTAMYEKDKADPKLKDYSELLFDQALLTEGSPIKDPLRFTKLVSELMVV
GGK

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI154146191, Length=687, Percent_Identity=40.3202328966521, Blast_Score=476, Evalue=1e-134,
Organism=Homo sapiens, GI153792590, Length=687, Percent_Identity=40.3202328966521, Blast_Score=474, Evalue=1e-133,
Organism=Homo sapiens, GI20149594, Length=681, Percent_Identity=40.2349486049927, Blast_Score=471, Evalue=1e-132,
Organism=Homo sapiens, GI4507677, Length=662, Percent_Identity=37.6132930513595, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI155722983, Length=647, Percent_Identity=35.0850077279753, Blast_Score=394, Evalue=1e-109,
Organism=Escherichia coli, GI1786679, Length=638, Percent_Identity=46.2382445141066, Blast_Score=573, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI17559162, Length=671, Percent_Identity=41.2816691505216, Blast_Score=483, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17542208, Length=667, Percent_Identity=37.0314842578711, Blast_Score=411, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI115535205, Length=651, Percent_Identity=33.1797235023041, Blast_Score=342, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI115535167, Length=437, Percent_Identity=35.4691075514874, Blast_Score=270, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6323840, Length=675, Percent_Identity=38.962962962963, Blast_Score=457, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6325016, Length=216, Percent_Identity=43.5185185185185, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI17647529, Length=681, Percent_Identity=40.3817914831131, Blast_Score=499, Evalue=1e-141,
Organism=Drosophila melanogaster, GI21357739, Length=675, Percent_Identity=38.2222222222222, Blast_Score=432, Evalue=1e-121,
Organism=Drosophila melanogaster, GI24586016, Length=637, Percent_Identity=36.5777080062794, Blast_Score=392, Evalue=1e-109,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 73927; Mature: 73796

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTVKKFETEVQQLLDLVIHSLYSNKEIFLRELISNASDAIDKIKFESHSNMELLEGNS
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
DWKIKLHADKEAGTLTVTDNGIGMSMDEVAENIGTIAKSGTKSFVAALKEQNLADNPELI
CEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHH
GQFGVGFYASFMVADKVVLTTRKAGGKEFGCRWESTGDGSYTIEECEKETRGTEIVLHLK
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCCEEEEEEH
DEMKEFLDEWKIRSIVKKYSDYVQYPVVMDITRTEPVKDAEGKVIEGGGTIEKTTEETLN
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHH
SMKAIWTRSKSEITEEEYDEFYKHISHDYDKPLSTIHYSAEGVSEFKAIVYIPSHKPYDL
HHHHHHHCCHHHCCHHHHHHHHHHHHCCCCCCHHHHEECCCCCCCCEEEEEECCCCCHHH
FLRDHKKGVHLYVKRVYITDNCEALLPDYLRFIKGVVDSSDLPLNVSREILQEDVQIKRI
HHHCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
QKSLVGKILSTLAEMKEKNFEEYLKFYAEFGPVLKEGIHFDHANKEKIQDLLLYESSKTE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCC
KGKYVSFKEYAERMPEGQKEIYFITGMSREAVENSPYMEALRKKDYEVLYMIDPVDEWVV
CCCEECHHHHHHHCCCCCCEEEEEECCCHHHHCCCHHHHHHHCCCCEEEEEECCHHHHHH
QAITEYQEKHLKAIDRGDLEIDTEEEKKEKEAKKEEAKKEYGSLMEFIQETLKEKVKEVR
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSRLTDSACCLVADEMGLNANMEKILKAMNQEVPEAKRILELNPDHQILQVMTAMYEKD
HHHCCCCCHHEEEECCCCCCCCHHHHHHHHHHCCCHHHHHEECCCCHHHHHHHHHHHHHC
KADPKLKDYSELLFDQALLTEGSPIKDPLRFTKLVSELMVVGGK
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKTVKKFETEVQQLLDLVIHSLYSNKEIFLRELISNASDAIDKIKFESHSNMELLEGNS
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
DWKIKLHADKEAGTLTVTDNGIGMSMDEVAENIGTIAKSGTKSFVAALKEQNLADNPELI
CEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHH
GQFGVGFYASFMVADKVVLTTRKAGGKEFGCRWESTGDGSYTIEECEKETRGTEIVLHLK
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCCEEEEEEH
DEMKEFLDEWKIRSIVKKYSDYVQYPVVMDITRTEPVKDAEGKVIEGGGTIEKTTEETLN
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHH
SMKAIWTRSKSEITEEEYDEFYKHISHDYDKPLSTIHYSAEGVSEFKAIVYIPSHKPYDL
HHHHHHHCCHHHCCHHHHHHHHHHHHCCCCCCHHHHEECCCCCCCCEEEEEECCCCCHHH
FLRDHKKGVHLYVKRVYITDNCEALLPDYLRFIKGVVDSSDLPLNVSREILQEDVQIKRI
HHHCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
QKSLVGKILSTLAEMKEKNFEEYLKFYAEFGPVLKEGIHFDHANKEKIQDLLLYESSKTE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCC
KGKYVSFKEYAERMPEGQKEIYFITGMSREAVENSPYMEALRKKDYEVLYMIDPVDEWVV
CCCEECHHHHHHHCCCCCCEEEEEECCCHHHHCCCHHHHHHHCCCCEEEEEECCHHHHHH
QAITEYQEKHLKAIDRGDLEIDTEEEKKEKEAKKEEAKKEYGSLMEFIQETLKEKVKEVR
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSRLTDSACCLVADEMGLNANMEKILKAMNQEVPEAKRILELNPDHQILQVMTAMYEKD
HHHCCCCCHHEEEECCCCCCCCHHHHHHHHHHCCCHHHHHEECCCCHHHHHHHHHHHHHC
KADPKLKDYSELLFDQALLTEGSPIKDPLRFTKLVSELMVVGGK
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA