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The map label for this gene is atoS [C]

Identifier: 197118795

GI number: 197118795

Start: 2801280

End: 2802848

Strand: Direct

Name: atoS [C]

Synonym: Gbem_2416

Alternate gene names: 197118795

Gene position: 2801280-2802848 (Clockwise)

Preceding gene: 197118793

Following gene: 197118796

Centisome position: 60.7

GC content: 63.22

Gene sequence:

>1569_bases
ATGAGCGATATCGAGAAGGGGTTTAAGACGCTGTTCCAGAACATGGAATTGGGTGCCTATCTGCAAAGCGCGGATGGCTC
CATGGTCGACGTCAATCCTGCAGCCTTATCCATGCTCGGATTGACCCGTGAGGAGTTCCTTGCCGGCTGCGGTCCCTCGC
CTTGCTGGCACCTGGCCGGTGAGAGCGGCGAGGAGCTTTTGCCCGACCAGCACCCCGCTGCGCTCGCCCTCGAGAGCGCA
CAGGAGGTCCGGGATTTCGTCGCCTCGGTGCATCAGGAGGGAGAACCTTTTCCGCTCTGGATCAACCTGAACGCGATACC
GCTGCGGGATGAAGAAGGGGGCGCCCCCCTCGCCGTCCTGGTCACGCTGAGGGACATCTCGAAGCTCAGGCGCCTGGAGC
AGGCTGTCGCCGCGACGGCCGCCGAGCGGGAACAGGAACAAAAGCAGTTGCAGGTGCACCACGCCAAGAAGCTGGAAAGC
CTCGGAGTCCTCGCCGGCGGCATCGCACACGATTTCAACAACATACTCACCTCCATCATGGGAAACACCGAGCTTGCGCT
GATGCAGCTCACCCCCGGGGCCCCTGCCTGCGAAAACTTGCGCCGGGTGGAACGGGCCTCCCACCGCGCTGCGGCCCTCC
TGAAGCAGATGCTTTTCTACCTGGGTAGAGGCACCTTTTCCTCCGAACCGATAGATCTGAACCGGTTGGTGGAGGAGATG
GCGGATATGCTGCAGGCTGCGATCTCCAAGAAGGCAACGCTGCGCCTGGAGCTCTCCCGGCCGCTGGGCCTTTTCAGCGC
CGACCCGGTCCAGGTGCGCCAAGTGGTGATGAACCTGGTCCTGAACGCTTCGGAAGCGCTCGGAAACGAGGTAGGCAAGA
TCAAAGTCTCCACCTCGCAAAGGCACTACCGTGAGGAAGAGCTTGCCGAGTTCCGCTGCAGCGAGGAACTCGCCCCAGGC
AGCTACCTGAGCCTGTCGGTGAGTGACACGGGTTACGGCATGGACAAGGAAACGAGGGCGCGGTTCTTCGACCGCCTGTT
CCCCGCTACCGGACGAGGGCTGGGTATGGCGGCCATCCTCGGCGTGGTCAGGGGGCTCAGAGGAGGGATGCGGCTGCAAA
GCGACGTGGGGAAAGGCTCCGCCTTCACGCTGCTGATCCCTGTGGACGCGGATGTGCTGACGGCCGCCAAGCCCGCCGAG
CGTGCCTCCGAACCGATGGGGATGGGCCCCGTGCTTTTGGTCGACGACGAAGAGGAGGTGTGCCTGTTGGTGGGCGCCAT
GCTGGAGCGGCTCGGGTACGAGGTGATCCCTGCAAGCGACGGCCATCAGGCTCTCGGGCTTTACCTGCAGCGCGACGACT
GGGCCTTCGTCATGCTGGACCTCACCATGCCGGTCATGGACGGCGAGGAGACCTACGAGCAGCTGCGCGGAATCGACCCG
TCGGTGAGGGTAGTCATCACCAGCGGCTACAGCGAAAACGAGGTGGCGCGCCGCTTCGAAGGAAAAGGGGTGAAGGGAGT
GCTGCAAAAACCTTTCGACATGGACGCGCTGCGCAGGGTTATCAGGTAG

Upstream 100 bases:

>100_bases
ATTTACAACCCATGAGATTTGCCATATATTCCTCTGGCTTTCATACGGTCCAGGCAGCGACAAGCCGTACCATCACGCCA
GATAGCGAAAGGGTGGTGAA

Downstream 100 bases:

>100_bases
GAGTTTTCCGGAGCCACATCCAAGGAGGCACAGAGATGGATATTTCCTTTCAGATACAAGATGCCGTCGCCTCGGTGATA
CGGGCGCCGCTTGCCTCCCC

Product: sensor histidine kinase response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MSDIEKGFKTLFQNMELGAYLQSADGSMVDVNPAALSMLGLTREEFLAGCGPSPCWHLAGESGEELLPDQHPAALALESA
QEVRDFVASVHQEGEPFPLWINLNAIPLRDEEGGAPLAVLVTLRDISKLRRLEQAVAATAAEREQEQKQLQVHHAKKLES
LGVLAGGIAHDFNNILTSIMGNTELALMQLTPGAPACENLRRVERASHRAAALLKQMLFYLGRGTFSSEPIDLNRLVEEM
ADMLQAAISKKATLRLELSRPLGLFSADPVQVRQVVMNLVLNASEALGNEVGKIKVSTSQRHYREEELAEFRCSEELAPG
SYLSLSVSDTGYGMDKETRARFFDRLFPATGRGLGMAAILGVVRGLRGGMRLQSDVGKGSAFTLLIPVDADVLTAAKPAE
RASEPMGMGPVLLVDDEEEVCLLVGAMLERLGYEVIPASDGHQALGLYLQRDDWAFVMLDLTMPVMDGEETYEQLRGIDP
SVRVVITSGYSENEVARRFEGKGVKGVLQKPFDMDALRRVIR

Sequences:

>Translated_522_residues
MSDIEKGFKTLFQNMELGAYLQSADGSMVDVNPAALSMLGLTREEFLAGCGPSPCWHLAGESGEELLPDQHPAALALESA
QEVRDFVASVHQEGEPFPLWINLNAIPLRDEEGGAPLAVLVTLRDISKLRRLEQAVAATAAEREQEQKQLQVHHAKKLES
LGVLAGGIAHDFNNILTSIMGNTELALMQLTPGAPACENLRRVERASHRAAALLKQMLFYLGRGTFSSEPIDLNRLVEEM
ADMLQAAISKKATLRLELSRPLGLFSADPVQVRQVVMNLVLNASEALGNEVGKIKVSTSQRHYREEELAEFRCSEELAPG
SYLSLSVSDTGYGMDKETRARFFDRLFPATGRGLGMAAILGVVRGLRGGMRLQSDVGKGSAFTLLIPVDADVLTAAKPAE
RASEPMGMGPVLLVDDEEEVCLLVGAMLERLGYEVIPASDGHQALGLYLQRDDWAFVMLDLTMPVMDGEETYEQLRGIDP
SVRVVITSGYSENEVARRFEGKGVKGVLQKPFDMDALRRVIR
>Mature_521_residues
SDIEKGFKTLFQNMELGAYLQSADGSMVDVNPAALSMLGLTREEFLAGCGPSPCWHLAGESGEELLPDQHPAALALESAQ
EVRDFVASVHQEGEPFPLWINLNAIPLRDEEGGAPLAVLVTLRDISKLRRLEQAVAATAAEREQEQKQLQVHHAKKLESL
GVLAGGIAHDFNNILTSIMGNTELALMQLTPGAPACENLRRVERASHRAAALLKQMLFYLGRGTFSSEPIDLNRLVEEMA
DMLQAAISKKATLRLELSRPLGLFSADPVQVRQVVMNLVLNASEALGNEVGKIKVSTSQRHYREEELAEFRCSEELAPGS
YLSLSVSDTGYGMDKETRARFFDRLFPATGRGLGMAAILGVVRGLRGGMRLQSDVGKGSAFTLLIPVDADVLTAAKPAER
ASEPMGMGPVLLVDDEEEVCLLVGAMLERLGYEVIPASDGHQALGLYLQRDDWAFVMLDLTMPVMDGEETYEQLRGIDPS
VRVVITSGYSENEVARRFEGKGVKGVLQKPFDMDALRRVIR

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=28.6290322580645, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=28.8, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788713, Length=375, Percent_Identity=27.2, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=313, Percent_Identity=24.9201277955272, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87081816, Length=418, Percent_Identity=21.7703349282297, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57014; Mature: 56883

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIEKGFKTLFQNMELGAYLQSADGSMVDVNPAALSMLGLTREEFLAGCGPSPCWHLAG
CCHHHHHHHHHHHCCCHHHHHCCCCCCEEECCHHHHHHHHCCHHHHHHCCCCCCCEECCC
ESGEELLPDQHPAALALESAQEVRDFVASVHQEGEPFPLWINLNAIPLRDEEGGAPLAVL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCCCEEEE
VTLRDISKLRRLEQAVAATAAEREQEQKQLQVHHAKKLESLGVLAGGIAHDFNNILTSIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNTELALMQLTPGAPACENLRRVERASHRAAALLKQMLFYLGRGTFSSEPIDLNRLVEEM
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
ADMLQAAISKKATLRLELSRPLGLFSADPVQVRQVVMNLVLNASEALGNEVGKIKVSTSQ
HHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCH
RHYREEELAEFRCSEELAPGSYLSLSVSDTGYGMDKETRARFFDRLFPATGRGLGMAAIL
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
GVVRGLRGGMRLQSDVGKGSAFTLLIPVDADVLTAAKPAERASEPMGMGPVLLVDDEEEV
HHHHHHCCCCEEHHCCCCCCEEEEEEECCCHHHHCCCCHHHCCCCCCCCCEEEEECCHHH
CLLVGAMLERLGYEVIPASDGHQALGLYLQRDDWAFVMLDLTMPVMDGEETYEQLRGIDP
HHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHCCCC
SVRVVITSGYSENEVARRFEGKGVKGVLQKPFDMDALRRVIR
CEEEEEECCCCHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHC
>Mature Secondary Structure 
SDIEKGFKTLFQNMELGAYLQSADGSMVDVNPAALSMLGLTREEFLAGCGPSPCWHLAG
CHHHHHHHHHHHCCCHHHHHCCCCCCEEECCHHHHHHHHCCHHHHHHCCCCCCCEECCC
ESGEELLPDQHPAALALESAQEVRDFVASVHQEGEPFPLWINLNAIPLRDEEGGAPLAVL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCCCEEEE
VTLRDISKLRRLEQAVAATAAEREQEQKQLQVHHAKKLESLGVLAGGIAHDFNNILTSIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNTELALMQLTPGAPACENLRRVERASHRAAALLKQMLFYLGRGTFSSEPIDLNRLVEEM
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
ADMLQAAISKKATLRLELSRPLGLFSADPVQVRQVVMNLVLNASEALGNEVGKIKVSTSQ
HHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCH
RHYREEELAEFRCSEELAPGSYLSLSVSDTGYGMDKETRARFFDRLFPATGRGLGMAAIL
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
GVVRGLRGGMRLQSDVGKGSAFTLLIPVDADVLTAAKPAERASEPMGMGPVLLVDDEEEV
HHHHHHCCCCEEHHCCCCCCEEEEEEECCCHHHHCCCCHHHCCCCCCCCCEEEEECCHHH
CLLVGAMLERLGYEVIPASDGHQALGLYLQRDDWAFVMLDLTMPVMDGEETYEQLRGIDP
HHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHCCCC
SVRVVITSGYSENEVARRFEGKGVKGVLQKPFDMDALRRVIR
CEEEEEECCCCHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA