Click here to switch to the map view.

The map label for this gene is csd [H]

Identifier: 197118672

GI number: 197118672

Start: 2661234

End: 2662376

Strand: Reverse

Name: csd [H]

Synonym: Gbem_2291

Alternate gene names: 197118672

Gene position: 2662376-2661234 (Counterclockwise)

Preceding gene: 197118673

Following gene: 197118671

Centisome position: 57.69

GC content: 65.79

Gene sequence:

>1143_bases
ATGCCCGTCTTCCTTGATAACGCCGCGACCTCATTCCCTAAACCGGAAACGGTCTACCTGGCCATGGACGCCGCCCTGCG
GGAAGTCGGGGTAGCGCCTGGAAGGGGGGGGTACCGGCAGTCCCTCGCTGCAGCCCGCATTGTCTACGAAGCCAGGTCGG
CCCTGGCGCGTTTTTTCGGCGTCTCGGACTCATCCCGCCTGATCTTCACCCACAGCGCAACGGAATCCATCAACATCGCG
GTCAACGGGCTTTTGAAGCCGGGCGACCATGTGGTATCCACCCGCGTCGAGCACAACGCGCTGCTGCGTCCGCTGCACTT
GGCGGCAAGCCGCGGCGTCGAAGTTACCTACGTCCCCTCGGACCGCTTCGGGGTAGTGTCGGAGCGGGAGATAGAGCGGG
CGATGCGCCCCGGCACGAGGCTCGTGGCGCTGGCGCACTGCTCGAACGTGACCGGAGCGGTGCAGCCGATCGAGGCGATT
GCGCGGGTGGCGCGGCAAAATGGCGCGGTTTTTCTGGTGGACGCGGCGCAAAGCGCCGGCTTTTTCCCCATTGAGGCGGA
GCGGACCGGCATCGACCTCCTCGCCGCACCTGGGCACAAGGGGCTCTATGGACCTCCCGGCACCGGCGTCCTCACCATTG
CGGAGGGGCTCAACCTGGAACCGCTGCTGGTGGGAGGGACCGGAGGAAGCGCAAGTAGCCCCGAGCAGCCCGACCAACTC
CCCGAGCGGCTGGAGAGCGGCACCATCAACACCCCTGCCATCGCCGGCCTTAAGGCGGGGGTCGAATTCGTACTCACTAC
CGGGATCGATGTGATCCGGGCCAAGGAAGAGCTACTGGTCAACCAGCTTTTGGAAGGGCTGCGAGCCACGCCTCACGTCG
AGGTCTACGGGCCGCTGGAGGGGGCGCGGGGCGCCGCGGTTTCCTTCAACGCGGCAGGGCACGATCCGGCGGCGCTCAGC
TTCCTTCTCGATTCCGATTACGACATAAGCGTCCGAGCCGGGCTCCACTGCGCCCCGGACACGCACCGCAGCATCGGGAC
CTACCCGACCGGAACGGTCAGGGTCAGTCCCGGGTTCTTTAACACAGAGGCTGACATAGACTTTTTCCTCAAAGCCCTGC
ACGAGATAGCGGCGCGCGGCTAG

Upstream 100 bases:

>100_bases
CCGAGCTGAAGATTTCCGATCTGAAACCGGTGCCGCTGGTCCCCTGAAAGGTTCATGAAAGCGGTTGCCAAACGACCCTC
AAAATGCTAGTAGATACCCT

Downstream 100 bases:

>100_bases
TCCGCGCCTCAACTGCAGGGATACTCACCAACTCTACGAAAGCGGCGCAAGCCGGGAAGGGGATTGATCCTACGAAAAGC
TCAAACTTAGCGGTTATTGA

Product: cysteine desulfurase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MPVFLDNAATSFPKPETVYLAMDAALREVGVAPGRGGYRQSLAAARIVYEARSALARFFGVSDSSRLIFTHSATESINIA
VNGLLKPGDHVVSTRVEHNALLRPLHLAASRGVEVTYVPSDRFGVVSEREIERAMRPGTRLVALAHCSNVTGAVQPIEAI
ARVARQNGAVFLVDAAQSAGFFPIEAERTGIDLLAAPGHKGLYGPPGTGVLTIAEGLNLEPLLVGGTGGSASSPEQPDQL
PERLESGTINTPAIAGLKAGVEFVLTTGIDVIRAKEELLVNQLLEGLRATPHVEVYGPLEGARGAAVSFNAAGHDPAALS
FLLDSDYDISVRAGLHCAPDTHRSIGTYPTGTVRVSPGFFNTEADIDFFLKALHEIAARG

Sequences:

>Translated_380_residues
MPVFLDNAATSFPKPETVYLAMDAALREVGVAPGRGGYRQSLAAARIVYEARSALARFFGVSDSSRLIFTHSATESINIA
VNGLLKPGDHVVSTRVEHNALLRPLHLAASRGVEVTYVPSDRFGVVSEREIERAMRPGTRLVALAHCSNVTGAVQPIEAI
ARVARQNGAVFLVDAAQSAGFFPIEAERTGIDLLAAPGHKGLYGPPGTGVLTIAEGLNLEPLLVGGTGGSASSPEQPDQL
PERLESGTINTPAIAGLKAGVEFVLTTGIDVIRAKEELLVNQLLEGLRATPHVEVYGPLEGARGAAVSFNAAGHDPAALS
FLLDSDYDISVRAGLHCAPDTHRSIGTYPTGTVRVSPGFFNTEADIDFFLKALHEIAARG
>Mature_379_residues
PVFLDNAATSFPKPETVYLAMDAALREVGVAPGRGGYRQSLAAARIVYEARSALARFFGVSDSSRLIFTHSATESINIAV
NGLLKPGDHVVSTRVEHNALLRPLHLAASRGVEVTYVPSDRFGVVSEREIERAMRPGTRLVALAHCSNVTGAVQPIEAIA
RVARQNGAVFLVDAAQSAGFFPIEAERTGIDLLAAPGHKGLYGPPGTGVLTIAEGLNLEPLLVGGTGGSASSPEQPDQLP
ERLESGTINTPAIAGLKAGVEFVLTTGIDVIRAKEELLVNQLLEGLRATPHVEVYGPLEGARGAAVSFNAAGHDPAALSF
LLDSDYDISVRAGLHCAPDTHRSIGTYPTGTVRVSPGFFNTEADIDFFLKALHEIAARG

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=387, Percent_Identity=27.6485788113695, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI156713448, Length=323, Percent_Identity=30.6501547987616, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1787970, Length=384, Percent_Identity=30.46875, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI48994898, Length=407, Percent_Identity=28.992628992629, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789175, Length=383, Percent_Identity=30.8093994778068, Blast_Score=136, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25143064, Length=383, Percent_Identity=27.154046997389, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17533177, Length=263, Percent_Identity=27.3764258555133, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319831, Length=393, Percent_Identity=28.7531806615776, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI20129463, Length=384, Percent_Identity=29.1666666666667, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 39998; Mature: 39867

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVFLDNAATSFPKPETVYLAMDAALREVGVAPGRGGYRQSLAAARIVYEARSALARFFG
CCEEECCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
VSDSSRLIFTHSATESINIAVNGLLKPGDHVVSTRVEHNALLRPLHLAASRGVEVTYVPS
CCCCCEEEEEECCCCEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEECC
DRFGVVSEREIERAMRPGTRLVALAHCSNVTGAVQPIEAIARVARQNGAVFLVDAAQSAG
CCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC
FFPIEAERTGIDLLAAPGHKGLYGPPGTGVLTIAEGLNLEPLLVGGTGGSASSPEQPDQL
CCEEECCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHH
PERLESGTINTPAIAGLKAGVEFVLTTGIDVIRAKEELLVNQLLEGLRATPHVEVYGPLE
HHHHHCCCCCCCHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GARGAAVSFNAAGHDPAALSFLLDSDYDISVRAGLHCAPDTHRSIGTYPTGTVRVSPGFF
CCCCCEEEECCCCCCHHEEEEEECCCCCEEEECCCEECCCCCCCCCCCCCCEEEECCCCC
NTEADIDFFLKALHEIAARG
CCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PVFLDNAATSFPKPETVYLAMDAALREVGVAPGRGGYRQSLAAARIVYEARSALARFFG
CEEECCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
VSDSSRLIFTHSATESINIAVNGLLKPGDHVVSTRVEHNALLRPLHLAASRGVEVTYVPS
CCCCCEEEEEECCCCEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEECC
DRFGVVSEREIERAMRPGTRLVALAHCSNVTGAVQPIEAIARVARQNGAVFLVDAAQSAG
CCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC
FFPIEAERTGIDLLAAPGHKGLYGPPGTGVLTIAEGLNLEPLLVGGTGGSASSPEQPDQL
CCEEECCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHH
PERLESGTINTPAIAGLKAGVEFVLTTGIDVIRAKEELLVNQLLEGLRATPHVEVYGPLE
HHHHHCCCCCCCHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GARGAAVSFNAAGHDPAALSFLLDSDYDISVRAGLHCAPDTHRSIGTYPTGTVRVSPGFF
CCCCCEEEECCCCCCHHEEEEEECCCCCEEEECCCEECCCCCCCCCCCCCCEEEECCCCC
NTEADIDFFLKALHEIAARG
CCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]