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The map label for this gene is atoS [C]

Identifier: 197118536

GI number: 197118536

Start: 2508263

End: 2510524

Strand: Direct

Name: atoS [C]

Synonym: Gbem_2155

Alternate gene names: 197118536

Gene position: 2508263-2510524 (Clockwise)

Preceding gene: 197118535

Following gene: 197118557

Centisome position: 54.35

GC content: 60.92

Gene sequence:

>2262_bases
ATGACGAGCCGCCTCGAAGTAAAGATCATCGTCTCCCTCGCCCTCATCCTCACCTTGCTCATCGCCGTTTACGGCTGGTG
GATCGGTAGCCGGCAGACCTCCGTCTACATTCAGACCCTCTCGGACAACCTGCGCATCCTCTCCCGCAGCAACGCCGACA
ACGCGGCCCATTTCATGGTGATAAAGGAATACGCCGGCTTGGAAGCGCACATGCTGGACAGTGCCAACCTCCCCGAGGTG
GTCAGCATCCAGGTCGCCGAACCGGACGGGAACCTTCTGTGCAACGTCGTGCGCCCCAACCGCGCCGACCTGCCCAAGGT
GAGCTACGACGTGAAGTGGGTCAGGGTGCCGCAGGGGTCCCAACCCGTTCTGAAGCGCGAGGGAAACCAACTGGTGAGCT
GGTCTCCCATCGTCGCCGGCGAAAAGCTTGGCTGGGTAAAGATCGCCCTGAGCCTGGATACGGCCCAGCGGCTCCTGCAT
GCAACCTGGCGCAGCACGCTTGTCATCGGTGCGCTCTGGATCATTGTGGGAACCGTGCTGATGGCACTGGTGGTCAAGCC
GCCGCTGCGGGCGGTCCGGGAGCTGGCCCGCTTCGCCCATGAGCTGCAAAACCGGAAGGGTGCGCAGGTCTCGGTGTCGC
GCGGGGTTTACGAAATCGACATGTTGACCGATGCTCTGAACCATTCGTCTGGGGAACTCCTTTTGGCCGAGCAGCGCCTG
TTAGCGGAACAGGAACGCCTCTCCGTAACGCTGCAATCCATCGGCGACGGCGTCATCGCCACCGACACCGAGAGCAGAAT
CGTGCTGGTCAACCACGTCGCCGAGCTTATGACCGGCTGGACCGAGAAACAGGCCACAGGCGTAGGCCTGGACCAGGTCC
TTTGCATCGAGCCAAGCGACTCCCTCCCGGACGTCGGGGAAGAGCTTCAGGCGGTAATGGAGCGAAGACAGACCATAGAG
CTCTCCGGCCTGCACCGGGTGTGGTCCCGGGACGGCGTTTCCCGCACGGTAACCGTGATCGGCGCTCCCATCATAGACAG
CGCGGCCCGGCTGGCAGGTATGGTGCTAGTGATCCGCGACCTGACGGAGAAGGCGAAGATGGAGGCCGAGAAGACGGGGC
TTGCCGAGCAACTGCTTCAGTCGCAGAAGATGGAGGCTGTAGGCAAGCTGGCCGGAGGGGTGGCGCATGATTTCAACAAC
ATGCTGGGGGTCATCATAGGCAATGCCGAGCTGGCCATGATGGAAGTCGAGCCTTCAGGGAAACTCCATGAACGGCTGCA
GGGGATCCTCGATGCCGCGAACCGCTCCGCCGATATCACCCGCCAACTGCTCGCTTTCTCCCGCCAGCAGCACGCAAAGC
CCAAGGTACTCGATCTGAACGAAGTGATCGCAAAGATGCTGAAGATGCTGCACAGGCTGATAGGCGAGGATATCGAGGTC
GTCTGGTCGCCGGGACGGGACATCTGGAAAGTGAAACTGGATCCGACCCAGTTGGACCAGATCATGGCCAACCTCTGCGT
CAACGCCAGGGACGCCATAGCGGGAATCGGGAGAATGGACATCCGGACGGAGAACGTCGAATTGTCACCTGAGCAAAAAA
ACCCCGCGGTAGAAATGCCCCAGGGAAGGTGCGTGATGCTGGAGGTGAGCGACAGTGGCTGCGGCATGAGGCGCGAGGTG
ATGGAAAGGATCTTCGAACCCTTCTACACCACAAAGGAGGTCGGGCGCGGAACTGGGCTTGGGCTCGCGACCGTTTTCGG
TATCGTGAAGCAAAACGACGGGCACATCGAGGTGCAGAGCGAGCCCGGGGCCGGTACCAGCTTCAGGATCTATTTCCCTG
CTGTCGAGGAGGAAGTTCAGGAGCATCAAAACAGGAGCGTCGTGGCTATAAGGGGGAACGAGACCATACTCATAGTGGAG
GACGAGCCGTCCATCAATGCGCTTGCCACCACCATGCTGTCCGAGCTTGGGTACCGGGTTCTGTCGGCGGGGACCCCTGG
CGAGGCTGTGAAGATGGCGGACGGCGGCCAGATGAAGATAGACCTGTTGCTGACGGACATCATAATGCCGGGCATGAACG
GGCGCGATTTGTCGGAGCTGCTGCAACGGTCGTATCCCGACATGAAGTGCCTGTTCATGTCGGGATATACAGCGGACATC
ATCTCGGAGCGCGGCAACATCGGACGAGAGGTCTGCTTCGTGCAAAAGCCCTTTACCACGCAGGCGCTGGCGGCGAAGGT
CAGAGAGGCGCTGCAGGCTTAG

Upstream 100 bases:

>100_bases
GCTTGTGGACCCGATAAAGGCGAACTTCAAGCGGGATTACAGCTTCTTTGCCAAGGTCGATCTTGAGGGACCTCGGCAAC
AGGCGAAGTAGCCCAGCCAG

Downstream 100 bases:

>100_bases
CTAAGGCACCTCATGTTCAAGGTTTTCCCTGGTCGATAAAGCGCCCCTGATATCGCGCCGATCCGATACAACGCTCGAAA
ACAAACTGGCAGATTTTGGT

Product: PAS domain-containing sensor histidine kinase response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 753; Mature: 752

Protein sequence:

>753_residues
MTSRLEVKIIVSLALILTLLIAVYGWWIGSRQTSVYIQTLSDNLRILSRSNADNAAHFMVIKEYAGLEAHMLDSANLPEV
VSIQVAEPDGNLLCNVVRPNRADLPKVSYDVKWVRVPQGSQPVLKREGNQLVSWSPIVAGEKLGWVKIALSLDTAQRLLH
ATWRSTLVIGALWIIVGTVLMALVVKPPLRAVRELARFAHELQNRKGAQVSVSRGVYEIDMLTDALNHSSGELLLAEQRL
LAEQERLSVTLQSIGDGVIATDTESRIVLVNHVAELMTGWTEKQATGVGLDQVLCIEPSDSLPDVGEELQAVMERRQTIE
LSGLHRVWSRDGVSRTVTVIGAPIIDSAARLAGMVLVIRDLTEKAKMEAEKTGLAEQLLQSQKMEAVGKLAGGVAHDFNN
MLGVIIGNAELAMMEVEPSGKLHERLQGILDAANRSADITRQLLAFSRQQHAKPKVLDLNEVIAKMLKMLHRLIGEDIEV
VWSPGRDIWKVKLDPTQLDQIMANLCVNARDAIAGIGRMDIRTENVELSPEQKNPAVEMPQGRCVMLEVSDSGCGMRREV
MERIFEPFYTTKEVGRGTGLGLATVFGIVKQNDGHIEVQSEPGAGTSFRIYFPAVEEEVQEHQNRSVVAIRGNETILIVE
DEPSINALATTMLSELGYRVLSAGTPGEAVKMADGGQMKIDLLLTDIIMPGMNGRDLSELLQRSYPDMKCLFMSGYTADI
ISERGNIGREVCFVQKPFTTQALAAKVREALQA

Sequences:

>Translated_753_residues
MTSRLEVKIIVSLALILTLLIAVYGWWIGSRQTSVYIQTLSDNLRILSRSNADNAAHFMVIKEYAGLEAHMLDSANLPEV
VSIQVAEPDGNLLCNVVRPNRADLPKVSYDVKWVRVPQGSQPVLKREGNQLVSWSPIVAGEKLGWVKIALSLDTAQRLLH
ATWRSTLVIGALWIIVGTVLMALVVKPPLRAVRELARFAHELQNRKGAQVSVSRGVYEIDMLTDALNHSSGELLLAEQRL
LAEQERLSVTLQSIGDGVIATDTESRIVLVNHVAELMTGWTEKQATGVGLDQVLCIEPSDSLPDVGEELQAVMERRQTIE
LSGLHRVWSRDGVSRTVTVIGAPIIDSAARLAGMVLVIRDLTEKAKMEAEKTGLAEQLLQSQKMEAVGKLAGGVAHDFNN
MLGVIIGNAELAMMEVEPSGKLHERLQGILDAANRSADITRQLLAFSRQQHAKPKVLDLNEVIAKMLKMLHRLIGEDIEV
VWSPGRDIWKVKLDPTQLDQIMANLCVNARDAIAGIGRMDIRTENVELSPEQKNPAVEMPQGRCVMLEVSDSGCGMRREV
MERIFEPFYTTKEVGRGTGLGLATVFGIVKQNDGHIEVQSEPGAGTSFRIYFPAVEEEVQEHQNRSVVAIRGNETILIVE
DEPSINALATTMLSELGYRVLSAGTPGEAVKMADGGQMKIDLLLTDIIMPGMNGRDLSELLQRSYPDMKCLFMSGYTADI
ISERGNIGREVCFVQKPFTTQALAAKVREALQA
>Mature_752_residues
TSRLEVKIIVSLALILTLLIAVYGWWIGSRQTSVYIQTLSDNLRILSRSNADNAAHFMVIKEYAGLEAHMLDSANLPEVV
SIQVAEPDGNLLCNVVRPNRADLPKVSYDVKWVRVPQGSQPVLKREGNQLVSWSPIVAGEKLGWVKIALSLDTAQRLLHA
TWRSTLVIGALWIIVGTVLMALVVKPPLRAVRELARFAHELQNRKGAQVSVSRGVYEIDMLTDALNHSSGELLLAEQRLL
AEQERLSVTLQSIGDGVIATDTESRIVLVNHVAELMTGWTEKQATGVGLDQVLCIEPSDSLPDVGEELQAVMERRQTIEL
SGLHRVWSRDGVSRTVTVIGAPIIDSAARLAGMVLVIRDLTEKAKMEAEKTGLAEQLLQSQKMEAVGKLAGGVAHDFNNM
LGVIIGNAELAMMEVEPSGKLHERLQGILDAANRSADITRQLLAFSRQQHAKPKVLDLNEVIAKMLKMLHRLIGEDIEVV
WSPGRDIWKVKLDPTQLDQIMANLCVNARDAIAGIGRMDIRTENVELSPEQKNPAVEMPQGRCVMLEVSDSGCGMRREVM
ERIFEPFYTTKEVGRGTGLGLATVFGIVKQNDGHIEVQSEPGAGTSFRIYFPAVEEEVQEHQNRSVVAIRGNETILIVED
EPSINALATTMLSELGYRVLSAGTPGEAVKMADGGQMKIDLLLTDIIMPGMNGRDLSELLQRSYPDMKCLFMSGYTADII
SERGNIGREVCFVQKPFTTQALAAKVREALQA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=369, Percent_Identity=26.8292682926829, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790436, Length=241, Percent_Identity=29.8755186721992, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI48994928, Length=519, Percent_Identity=23.8921001926782, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=271, Percent_Identity=27.6752767527675, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI145693157, Length=328, Percent_Identity=26.219512195122, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=288, Percent_Identity=26.0416666666667, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=373, Percent_Identity=22.7882037533512, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1788381, Length=211, Percent_Identity=32.7014218009479, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786837, Length=388, Percent_Identity=24.4845360824742, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82765; Mature: 82634

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRLEVKIIVSLALILTLLIAVYGWWIGSRQTSVYIQTLSDNLRILSRSNADNAAHFMV
CCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCEEEEE
IKEYAGLEAHMLDSANLPEVVSIQVAEPDGNLLCNVVRPNRADLPKVSYDVKWVRVPQGS
EHHHCCCEEEECCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEECEEEEECCCCC
QPVLKREGNQLVSWSPIVAGEKLGWVKIALSLDTAQRLLHATWRSTLVIGALWIIVGTVL
CCHHHCCCCCEEEECCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MALVVKPPLRAVRELARFAHELQNRKGAQVSVSRGVYEIDMLTDALNHSSGELLLAEQRL
HHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEHHHHHHHHCCCCCCEEEHHHHH
LAEQERLSVTLQSIGDGVIATDTESRIVLVNHVAELMTGWTEKQATGVGLDQVLCIEPSD
HHHHHHHHHHHHHHCCCEEEECCCCCEEEHHHHHHHHHCCCHHHCCCCCCCEEEEECCCC
SLPDVGEELQAVMERRQTIELSGLHRVWSRDGVSRTVTVIGAPIIDSAARLAGMVLVIRD
CCCCHHHHHHHHHHHHHEEEHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHH
LTEKAKMEAEKTGLAEQLLQSQKMEAVGKLAGGVAHDFNNMLGVIIGNAELAMMEVEPSG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCEEEEECCCEEEEEEECCCC
KLHERLQGILDAANRSADITRQLLAFSRQQHAKPKVLDLNEVIAKMLKMLHRLIGEDIEV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHCCCCEEE
VWSPGRDIWKVKLDPTQLDQIMANLCVNARDAIAGIGRMDIRTENVELSPEQKNPAVEMP
EECCCCCEEEEEECHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCEECCCCCCCCCCCC
QGRCVMLEVSDSGCGMRREVMERIFEPFYTTKEVGRGTGLGLATVFGIVKQNDGHIEVQS
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEC
EPGAGTSFRIYFPAVEEEVQEHQNRSVVAIRGNETILIVEDEPSINALATTMLSELGYRV
CCCCCCEEEEEECHHHHHHHHHCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCHHE
LSAGTPGEAVKMADGGQMKIDLLLTDIIMPGMNGRDLSELLQRSYPDMKCLFMSGYTADI
ECCCCCCCEEEECCCCCEEEEEEEHHHHCCCCCCCCHHHHHHHCCCCEEEEEECCCHHHH
ISERGNIGREVCFVQKPFTTQALAAKVREALQA
HHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSRLEVKIIVSLALILTLLIAVYGWWIGSRQTSVYIQTLSDNLRILSRSNADNAAHFMV
CCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCEEEEE
IKEYAGLEAHMLDSANLPEVVSIQVAEPDGNLLCNVVRPNRADLPKVSYDVKWVRVPQGS
EHHHCCCEEEECCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEECEEEEECCCCC
QPVLKREGNQLVSWSPIVAGEKLGWVKIALSLDTAQRLLHATWRSTLVIGALWIIVGTVL
CCHHHCCCCCEEEECCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MALVVKPPLRAVRELARFAHELQNRKGAQVSVSRGVYEIDMLTDALNHSSGELLLAEQRL
HHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEHHHHHHHHCCCCCCEEEHHHHH
LAEQERLSVTLQSIGDGVIATDTESRIVLVNHVAELMTGWTEKQATGVGLDQVLCIEPSD
HHHHHHHHHHHHHHCCCEEEECCCCCEEEHHHHHHHHHCCCHHHCCCCCCCEEEEECCCC
SLPDVGEELQAVMERRQTIELSGLHRVWSRDGVSRTVTVIGAPIIDSAARLAGMVLVIRD
CCCCHHHHHHHHHHHHHEEEHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHH
LTEKAKMEAEKTGLAEQLLQSQKMEAVGKLAGGVAHDFNNMLGVIIGNAELAMMEVEPSG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCEEEEECCCEEEEEEECCCC
KLHERLQGILDAANRSADITRQLLAFSRQQHAKPKVLDLNEVIAKMLKMLHRLIGEDIEV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHCCCCEEE
VWSPGRDIWKVKLDPTQLDQIMANLCVNARDAIAGIGRMDIRTENVELSPEQKNPAVEMP
EECCCCCEEEEEECHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCEECCCCCCCCCCCC
QGRCVMLEVSDSGCGMRREVMERIFEPFYTTKEVGRGTGLGLATVFGIVKQNDGHIEVQS
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEC
EPGAGTSFRIYFPAVEEEVQEHQNRSVVAIRGNETILIVEDEPSINALATTMLSELGYRV
CCCCCCEEEEEECHHHHHHHHHCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCHHE
LSAGTPGEAVKMADGGQMKIDLLLTDIIMPGMNGRDLSELLQRSYPDMKCLFMSGYTADI
ECCCCCCCEEEECCCCCEEEEEEEHHHHCCCCCCCCHHHHHHHCCCCEEEEEECCCHHHH
ISERGNIGREVCFVQKPFTTQALAAKVREALQA
HHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA