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The map label for this gene is etfA-6 [H]

Identifier: 197118468

GI number: 197118468

Start: 2411098

End: 2412408

Strand: Direct

Name: etfA-6 [H]

Synonym: Gbem_2086

Alternate gene names: 197118468

Gene position: 2411098-2412408 (Clockwise)

Preceding gene: 197118467

Following gene: 197118469

Centisome position: 52.24

GC content: 65.14

Gene sequence:

>1311_bases
ATGAGCGAACCAGCAAAAGTGAAGAAGCCTCGCGGCAAGGCGCGGGTGATAGCGGGGAAATGCATCGCCTGCGGCGCGCG
CTGCCAGAGCGTTTGCCCCATAAACGGCGTGGAGATGAGCGAACAGGGCGAACCGGTCATCGAAACGGAAAAATGCATCG
GCTGCGTCAAGTGCGTGAAGGCCTGCCCCGCCGGCGCGCTGGAGATGTTCTACACCCCGGAAGAGTTGGCTATCATCGCG
AGCTTCGAGAAGCACGGCGGCGAGGAGGTCGACGAAGAGGAGCTTGAGCGTCGCAGGAATGTGGCGGCCTACAAGGGGGT
CTGGGTCTTCGTCGAGCAAAACGACGGGGAGGCGGCGAAGGTCTCCTGGGAGTTGACCGGCGTGGGGCGCGAGCTTGCCG
ATACGCTGGGGGTACCGCTCTCCGCGGTCATCATAGGGAGCGGCGTGGATCATCTAGCCGACACCGCCTTCAGCTACGGC
GCCGACCAGGCCTACCTCATCGACGACCCGGTGTTCCGCCAGTACCGGACCGAGCCGTTCCTCGCGGCGATGTGCCACCT
GATCGAAAAGCACAAGCCCGAGGTGGTCCTCATGGGGGCGACCGGTATGGGGCGCGACCTGGCCGGCGCGGTGGCAACCC
GCGTCAAGACAGGCCTCACCGCCGACTGCACCGGACTAGGCATCGACGCCAAGGGAAACCTGATGCAGACGCGTCCGGCA
TTCGGCGGCAACATCATGGCGACCATCATGTGCGACCGCTTCCGCCCCCAGATGGCCACGGTACGCCCGCATGTCATGCC
CATGCCGCAGCAGCGCGCAGGTGCGAAGGGCACTATCATCCCGGAGAGCTGTCCCATCCCGGAATCCTCGATCTTCACCC
GGGTATTGGAAGTGATCACGGACAAGGGGGGGAAGGACAAGGTCGACGTGGCGGGAGCCGAGTTCATCGTCTCCGGCGGC
CGTGGACTGATGGCGAAGGAAAACTTCGCCCTGCTGGAGGAACTCGCCGAGGAGTTGGGCGGGGTGGTGGGGGGCTCGCG
CAGCGCGGTCGACGCGGGGTGGCTGCCGCAGGACCGGCAGGTGGGGCAAACGGGCAAGACGGTCCGGCCCAAGATCTACA
TCGCCTGCGGCATCTCCGGCGCCATTCAGCACTTGGTCGGCATGCAGGATTCCGACGTCATCGTCGCCATCAACCGCGAC
CCCGAAGCGCCTATCTTCGAGGTGGCGACCTTCGGCATCGTCGGGGACCTTTTCGAGGTGGTGCCGGCCCTGACTGCCCG
GGTGCGGGAAATGAAACAGCTGAGAAGCTGA

Upstream 100 bases:

>100_bases
CGAAAGCGCTCCATCCCCCAGCGGGGGAGGGTTGGGGTGGGGGAAGGCAACGTGCCACGTCGGCCACATTATAAGATCAG
CGATCACAGAAGGTGACCCA

Downstream 100 bases:

>100_bases
AGCGCAAGTAAACCTTCGATCCTGCCGGGAGTCATACCTATGGAACATACTTTTTTCGCTGTCCTGCTGTCGCTTTCCAT
GGCTGCTTTTGCCTTCAGTT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSEPAKVKKPRGKARVIAGKCIACGARCQSVCPINGVEMSEQGEPVIETEKCIGCVKCVKACPAGALEMFYTPEELAIIA
SFEKHGGEEVDEEELERRRNVAAYKGVWVFVEQNDGEAAKVSWELTGVGRELADTLGVPLSAVIIGSGVDHLADTAFSYG
ADQAYLIDDPVFRQYRTEPFLAAMCHLIEKHKPEVVLMGATGMGRDLAGAVATRVKTGLTADCTGLGIDAKGNLMQTRPA
FGGNIMATIMCDRFRPQMATVRPHVMPMPQQRAGAKGTIIPESCPIPESSIFTRVLEVITDKGGKDKVDVAGAEFIVSGG
RGLMAKENFALLEELAEELGGVVGGSRSAVDAGWLPQDRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVIVAINRD
PEAPIFEVATFGIVGDLFEVVPALTARVREMKQLRS

Sequences:

>Translated_436_residues
MSEPAKVKKPRGKARVIAGKCIACGARCQSVCPINGVEMSEQGEPVIETEKCIGCVKCVKACPAGALEMFYTPEELAIIA
SFEKHGGEEVDEEELERRRNVAAYKGVWVFVEQNDGEAAKVSWELTGVGRELADTLGVPLSAVIIGSGVDHLADTAFSYG
ADQAYLIDDPVFRQYRTEPFLAAMCHLIEKHKPEVVLMGATGMGRDLAGAVATRVKTGLTADCTGLGIDAKGNLMQTRPA
FGGNIMATIMCDRFRPQMATVRPHVMPMPQQRAGAKGTIIPESCPIPESSIFTRVLEVITDKGGKDKVDVAGAEFIVSGG
RGLMAKENFALLEELAEELGGVVGGSRSAVDAGWLPQDRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVIVAINRD
PEAPIFEVATFGIVGDLFEVVPALTARVREMKQLRS
>Mature_435_residues
SEPAKVKKPRGKARVIAGKCIACGARCQSVCPINGVEMSEQGEPVIETEKCIGCVKCVKACPAGALEMFYTPEELAIIAS
FEKHGGEEVDEEELERRRNVAAYKGVWVFVEQNDGEAAKVSWELTGVGRELADTLGVPLSAVIIGSGVDHLADTAFSYGA
DQAYLIDDPVFRQYRTEPFLAAMCHLIEKHKPEVVLMGATGMGRDLAGAVATRVKTGLTADCTGLGIDAKGNLMQTRPAF
GGNIMATIMCDRFRPQMATVRPHVMPMPQQRAGAKGTIIPESCPIPESSIFTRVLEVITDKGGKDKVDVAGAEFIVSGGR
GLMAKENFALLEELAEELGGVVGGSRSAVDAGWLPQDRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVIVAINRDP
EAPIFEVATFGIVGDLFEVVPALTARVREMKQLRS

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=335, Percent_Identity=35.2238805970149, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI189181759, Length=228, Percent_Identity=43.421052631579, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI1787990, Length=257, Percent_Identity=30.3501945525292, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786226, Length=254, Percent_Identity=32.2834645669291, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082157, Length=261, Percent_Identity=26.4367816091954, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=141, Percent_Identity=57.4468085106383, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6325261, Length=335, Percent_Identity=31.044776119403, Blast_Score=152, Evalue=9e-38,
Organism=Drosophila melanogaster, GI17136898, Length=271, Percent_Identity=39.8523985239852, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24652801, Length=271, Percent_Identity=39.8523985239852, Blast_Score=181, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 46633; Mature: 46502

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00198 4FE4S_FERREDOXIN ; PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPAKVKKPRGKARVIAGKCIACGARCQSVCPINGVEMSEQGEPVIETEKCIGCVKCVK
CCCCCCCCCCCCCEEEEECHHHHCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ACPAGALEMFYTPEELAIIASFEKHGGEEVDEEELERRRNVAAYKGVWVFVEQNDGEAAK
HCCCCCHHEEECHHHHEEEEEHHHCCCCCCCHHHHHHHHCCEEECEEEEEEECCCCCEEE
VSWELTGVGRELADTLGVPLSAVIIGSGVDHLADTAFSYGADQAYLIDDPVFRQYRTEPF
EEEEEECCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCEEEECCHHHHHHCCCHH
LAAMCHLIEKHKPEVVLMGATGMGRDLAGAVATRVKTGLTADCTGLGIDAKGNLMQTRPA
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCC
FGGNIMATIMCDRFRPQMATVRPHVMPMPQQRAGAKGTIIPESCPIPESSIFTRVLEVIT
CCCCEEEEEEHHHCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
DKGGKDKVDVAGAEFIVSGGRGLMAKENFALLEELAEELGGVVGGSRSAVDAGWLPQDRQ
CCCCCCCEEECCCEEEEECCCCCEECCHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCCCC
VGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVIVAINRDPEAPIFEVATFGIVGDLFEV
CCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
VPALTARVREMKQLRS
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEPAKVKKPRGKARVIAGKCIACGARCQSVCPINGVEMSEQGEPVIETEKCIGCVKCVK
CCCCCCCCCCCCEEEEECHHHHCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ACPAGALEMFYTPEELAIIASFEKHGGEEVDEEELERRRNVAAYKGVWVFVEQNDGEAAK
HCCCCCHHEEECHHHHEEEEEHHHCCCCCCCHHHHHHHHCCEEECEEEEEEECCCCCEEE
VSWELTGVGRELADTLGVPLSAVIIGSGVDHLADTAFSYGADQAYLIDDPVFRQYRTEPF
EEEEEECCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCEEEECCHHHHHHCCCHH
LAAMCHLIEKHKPEVVLMGATGMGRDLAGAVATRVKTGLTADCTGLGIDAKGNLMQTRPA
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCC
FGGNIMATIMCDRFRPQMATVRPHVMPMPQQRAGAKGTIIPESCPIPESSIFTRVLEVIT
CCCCEEEEEEHHHCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
DKGGKDKVDVAGAEFIVSGGRGLMAKENFALLEELAEELGGVVGGSRSAVDAGWLPQDRQ
CCCCCCCEEECCCEEEEECCCCCEECCHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCCCC
VGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVIVAINRDPEAPIFEVATFGIVGDLFEV
CCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
VPALTARVREMKQLRS
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA