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The map label for this gene is aphA [H]

Identifier: 197118406

GI number: 197118406

Start: 2330264

End: 2331817

Strand: Reverse

Name: aphA [H]

Synonym: Gbem_2024

Alternate gene names: 197118406

Gene position: 2331817-2330264 (Counterclockwise)

Preceding gene: 197118407

Following gene: 197118405

Centisome position: 50.53

GC content: 61.84

Gene sequence:

>1554_bases
ATGGGCGGATTAGCCATCGAGGACCCGGGCTTCACCCTTTTGTACGTGGAGGACGAGCAGGTCACCAGGGAGACGGTGCT
TTCCCTTTTGCAGCGGCGCTTTCCCAAGCTCGCCCTTTTAAGCGCGGCAAACGGCGCCGAAGGCATGGCGCTTTTCCGGG
AGCACGCACCCGACCTCGTGGTGACCGACATCAAGATGCCGGCCATGAGTGGCATCGACATGGCGCGGGAAATGATGGAG
CAAAAACCTTCCCTCCCGGTGATCGTCACCAGCGCTCATTCCGACATGGAGTACCTGATCGAGTCGATCGAGCTGGGGAT
CAGCCGCTACGTCCTGAAGCCGATAGACAGCTCGAAGCTCTTCGCGGCGGTGGAAAGCGCGCTTACAACCCTCACCCAGG
AAAGGGAGCTATTGGCCCACCAGGTGTTCGTGCGCAGGCTCTCGCGGGCGGTGGAGCAGAGCGCCAGCAGCATCGTCATC
GCCAACCCTGAAGGGGTGATCGACTACGTGAACCCCAGGTTCACCACGCTGACCGGCTACGAGCCCGGCGAGGTGCTGGG
AAAAAACCTGAAGTCGCTGAAAGGAAAAGCCGAACTATGGGACCGGGTCGCAGCCGGAGAGGAGTGGCACGGCGAGTTCG
AGGGGGTGAAGAAGAACGGCGAGGTTTTCTACGAGTCCACCTCCCTCTCCCCCGTCTACGACGAGACCGGCGCTCTCAGC
GACCTGGTCGCGGTGCAGGAGGAGATCACCGAAAGGGTGCTGTCCGAGCGACGGATCGAGGCGTTGAACCGGAACCTCGC
GGCGCGAGCCGAGGAACTGGAACTCGCGAACCGCGACCTGGAGGGGTTCAGCTACACGGTCTCGCACGATCTGCGCACGC
CGCTGACCAACATCAACGGCTACTGCCAGGTGATACTGGAGCTTTACGGCGCGACGCTGGACGAGCAGTGCAAGGATTTC
ATCAAGATCATCTTCGACGAAACCGTCAACATGAACCAGTTGATCAAGACGCTGCTTGAATTCTCCCGGGTGAGCCGCAG
CGAGATGACCCGGTCCGAGGTTGATTTGAGCCAGCTTACCTCCCTGGTCTGCGCCTCCCAGCAATTGAGCGAACCGCAGC
GGCGGGTGACCTTCAGCATAGCCCCCGGGATGACGGCCCTTGGGGACCCCGACCTTTTGAAGGTGGTGCTGCAAAACCTG
ATCTCCAACGCCTGCAAATACTCGGCGAACCGGGAAGACGCCGCGGTCGAAGTAGCCTCCCTGGACGAGAGCGGGGAGCT
CGTTTACTTCGTGCGCGACAACGGCGCCGGCTTCGACATGACGCTGGCCGACAAACTGTTCAGCCCCTTCCAGCGGCTCC
ACTCGGAGCGGGAGTTCAAGGGGTTCGGCATAGGACTCGCCACCGTGCAGCGCATCATCCAGCGCCACGGCGGCAGGATC
TGGGCCGAGGGAGAGGTAGGGCTCGGGGCCTGCTTCTACTTCACCCTCCCCGATGAAAACACGAGGCACGGAGCAGACCA
CTGTTCGGCAAGGCAGGAGGAGCGCAAAAAGTGA

Upstream 100 bases:

>100_bases
GGCCTTTTCATGGCCAAGAACATCGTGGAAAAAAGCATGAACGGCTCGCTCACCGCAAGAAACATCGAGGGCGGGGCCGA
ATTCAGGATCGAGGTGTAGC

Downstream 100 bases:

>100_bases
ACAAAGAAATGAAGTACACGCAACGGATTCTGCTCATCGACGACGAGGCGCAGATACTGGAAACCTGCCGGAGCTGCCTC
AACAACGCCGGGCACGCCGA

Product: response receiver sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MGGLAIEDPGFTLLYVEDEQVTRETVLSLLQRRFPKLALLSAANGAEGMALFREHAPDLVVTDIKMPAMSGIDMAREMME
QKPSLPVIVTSAHSDMEYLIESIELGISRYVLKPIDSSKLFAAVESALTTLTQERELLAHQVFVRRLSRAVEQSASSIVI
ANPEGVIDYVNPRFTTLTGYEPGEVLGKNLKSLKGKAELWDRVAAGEEWHGEFEGVKKNGEVFYESTSLSPVYDETGALS
DLVAVQEEITERVLSERRIEALNRNLAARAEELELANRDLEGFSYTVSHDLRTPLTNINGYCQVILELYGATLDEQCKDF
IKIIFDETVNMNQLIKTLLEFSRVSRSEMTRSEVDLSQLTSLVCASQQLSEPQRRVTFSIAPGMTALGDPDLLKVVLQNL
ISNACKYSANREDAAVEVASLDESGELVYFVRDNGAGFDMTLADKLFSPFQRLHSEREFKGFGIGLATVQRIIQRHGGRI
WAEGEVGLGACFYFTLPDENTRHGADHCSARQEERKK

Sequences:

>Translated_517_residues
MGGLAIEDPGFTLLYVEDEQVTRETVLSLLQRRFPKLALLSAANGAEGMALFREHAPDLVVTDIKMPAMSGIDMAREMME
QKPSLPVIVTSAHSDMEYLIESIELGISRYVLKPIDSSKLFAAVESALTTLTQERELLAHQVFVRRLSRAVEQSASSIVI
ANPEGVIDYVNPRFTTLTGYEPGEVLGKNLKSLKGKAELWDRVAAGEEWHGEFEGVKKNGEVFYESTSLSPVYDETGALS
DLVAVQEEITERVLSERRIEALNRNLAARAEELELANRDLEGFSYTVSHDLRTPLTNINGYCQVILELYGATLDEQCKDF
IKIIFDETVNMNQLIKTLLEFSRVSRSEMTRSEVDLSQLTSLVCASQQLSEPQRRVTFSIAPGMTALGDPDLLKVVLQNL
ISNACKYSANREDAAVEVASLDESGELVYFVRDNGAGFDMTLADKLFSPFQRLHSEREFKGFGIGLATVQRIIQRHGGRI
WAEGEVGLGACFYFTLPDENTRHGADHCSARQEERKK
>Mature_516_residues
GGLAIEDPGFTLLYVEDEQVTRETVLSLLQRRFPKLALLSAANGAEGMALFREHAPDLVVTDIKMPAMSGIDMAREMMEQ
KPSLPVIVTSAHSDMEYLIESIELGISRYVLKPIDSSKLFAAVESALTTLTQERELLAHQVFVRRLSRAVEQSASSIVIA
NPEGVIDYVNPRFTTLTGYEPGEVLGKNLKSLKGKAELWDRVAAGEEWHGEFEGVKKNGEVFYESTSLSPVYDETGALSD
LVAVQEEITERVLSERRIEALNRNLAARAEELELANRDLEGFSYTVSHDLRTPLTNINGYCQVILELYGATLDEQCKDFI
KIIFDETVNMNQLIKTLLEFSRVSRSEMTRSEVDLSQLTSLVCASQQLSEPQRRVTFSIAPGMTALGDPDLLKVVLQNLI
SNACKYSANREDAAVEVASLDESGELVYFVRDNGAGFDMTLADKLFSPFQRLHSEREFKGFGIGLATVQRIIQRHGGRIW
AEGEVGLGACFYFTLPDENTRHGADHCSARQEERKK

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=361, Percent_Identity=27.7008310249307, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI48994928, Length=276, Percent_Identity=27.536231884058, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=29.7872340425532, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=220, Percent_Identity=30, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=28.310502283105, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789808, Length=193, Percent_Identity=30.5699481865285, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=27.6150627615063, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=218, Percent_Identity=29.8165137614679, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788905, Length=268, Percent_Identity=25.7462686567164, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=264, Percent_Identity=26.5151515151515, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=28.3185840707965, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789149, Length=254, Percent_Identity=25.5905511811024, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790299, Length=93, Percent_Identity=32.258064516129, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=24.8908296943231, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788550, Length=96, Percent_Identity=35.4166666666667, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790861, Length=203, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787894, Length=217, Percent_Identity=29.9539170506912, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=290, Percent_Identity=26.8965517241379, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790551, Length=208, Percent_Identity=28.8461538461538, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786784, Length=194, Percent_Identity=27.8350515463918, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=24.4343891402715, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=108, Percent_Identity=35.1851851851852, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57560; Mature: 57429

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGLAIEDPGFTLLYVEDEQVTRETVLSLLQRRFPKLALLSAANGAEGMALFREHAPDLV
CCCCEECCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCEE
VTDIKMPAMSGIDMAREMMEQKPSLPVIVTSAHSDMEYLIESIELGISRYVLKPIDSSKL
EECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
FAAVESALTTLTQERELLAHQVFVRRLSRAVEQSASSIVIANPEGVIDYVNPRFTTLTGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCCCEEEECCC
EPGEVLGKNLKSLKGKAELWDRVAAGEEWHGEFEGVKKNGEVFYESTSLSPVYDETGALS
CCHHHHHHHHHHHCCHHHHHHHHHCCCHHCCHHCCCCCCCCEEEECCCCCCCCCCCCHHH
DLVAVQEEITERVLSERRIEALNRNLAARAEELELANRDLEGFSYTVSHDLRTPLTNING
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCH
YCQVILELYGATLDEQCKDFIKIIFDETVNMNQLIKTLLEFSRVSRSEMTRSEVDLSQLT
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SLVCASQQLSEPQRRVTFSIAPGMTALGDPDLLKVVLQNLISNACKYSANREDAAVEVAS
HHHHHHHHHCCHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEE
LDESGELVYFVRDNGAGFDMTLADKLFSPFQRLHSEREFKGFGIGLATVQRIIQRHGGRI
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEE
WAEGEVGLGACFYFTLPDENTRHGADHCSARQEERKK
EECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GGLAIEDPGFTLLYVEDEQVTRETVLSLLQRRFPKLALLSAANGAEGMALFREHAPDLV
CCCEECCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCEE
VTDIKMPAMSGIDMAREMMEQKPSLPVIVTSAHSDMEYLIESIELGISRYVLKPIDSSKL
EECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
FAAVESALTTLTQERELLAHQVFVRRLSRAVEQSASSIVIANPEGVIDYVNPRFTTLTGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCCCEEEECCC
EPGEVLGKNLKSLKGKAELWDRVAAGEEWHGEFEGVKKNGEVFYESTSLSPVYDETGALS
CCHHHHHHHHHHHCCHHHHHHHHHCCCHHCCHHCCCCCCCCEEEECCCCCCCCCCCCHHH
DLVAVQEEITERVLSERRIEALNRNLAARAEELELANRDLEGFSYTVSHDLRTPLTNING
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCH
YCQVILELYGATLDEQCKDFIKIIFDETVNMNQLIKTLLEFSRVSRSEMTRSEVDLSQLT
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SLVCASQQLSEPQRRVTFSIAPGMTALGDPDLLKVVLQNLISNACKYSANREDAAVEVAS
HHHHHHHHHCCHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEE
LDESGELVYFVRDNGAGFDMTLADKLFSPFQRLHSEREFKGFGIGLATVQRIIQRHGGRI
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEE
WAEGEVGLGACFYFTLPDENTRHGADHCSARQEERKK
EECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]