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The map label for this gene is ntrC [H]

Identifier: 197118405

GI number: 197118405

Start: 2328846

End: 2330267

Strand: Reverse

Name: ntrC [H]

Synonym: Gbem_2023

Alternate gene names: 197118405

Gene position: 2330267-2328846 (Counterclockwise)

Preceding gene: 197118406

Following gene: 197118396

Centisome position: 50.49

GC content: 60.97

Gene sequence:

>1422_bases
GTGAACAAAGAAATGAAGTACACGCAACGGATTCTGCTCATCGACGACGAGGCGCAGATACTGGAAACCTGCCGGAGCTG
CCTCAACAACGCCGGGCACGCCGATGTAGTCATCGAAAACGACAGCAGCAAGGTGATGTCGCTTCTTTCCAGAGAAGAAT
TCGCCGTCATCGTCCTGGACCTGCGCATGCCGAACCTCTCCGGGTTCGAACTCCTGCCGCAGATAATCTCGCAACACCCT
CAGATCAAGGTGATAGTCGCCACCGCCAACAACGACGTCGAAACCGTGGTGAATTGCATCAAGGAGGGGGCCTTCGACTA
CCTGGTGAAGCCCATTGACGTAAAGCGGCTGATCACCTCGGTCAGGAAAGCCCTGGAGATGCGCTCCCTCGCCAACGAGC
TCACCGCCTTGAAGCAGTACATGTTCACCGACCGGTTGGACCATCCCGAGGCCTTCCGGAGCATCGTCACCGGCAACAAG
GCGATGCGGGCCATCTTCCAGTACCTCGAGGTGATTTCCGGCACTAGGCAGGCGGTAACGATTACCGGCGAGACCGGCAC
CGGCAAGGAGCTGATAGCCCGGGCGATCCACAACCTGAGTGGCTGCAGCGGCGAGTACGTGGCGCTCAACGTGGCAGGGC
TCGACGACAACATGTTTTCCGACACCCTTTTCGGTCACAGGAAAGGCGCCTTCACCGGCGCCGACCAGGCCCGGGACGGC
CTGATCACCCGCGCCTCCGGAGGGACGCTCTTTTTAGACGAGATAGGCGACCTCAACGAGATGTCGCAGATCAAGCTCTT
GAGGCTTTTGCAGGAGCAGGAGTACTACCCCGTCGGCTCCGACTTCATCAAGAAGAGCGACGCGCGTCTGGTGCTCGCCA
CCAACCGCGACCTTCAGGAGCTGATCAAGCAGGGGAAATTTCGCAACGACCTCTACTACCGGCTCTGCGGGCACCGGGTG
CATCTCCCCCCGCTGCGGGACAGGCTGGACGACATTCCGCTCCTTTTGGAACACTTCCTGGGAAGCGCCGCCGACTGCCT
GGGCAAGAAGAAGCCGACCCCTCCCCCCGAGCTTGCCGTCATGCTCGCGCTTTACCACTTCCCTGGCAACATCCGGGAGT
TGGAGGCGCTCGTGTTCGACGCCGTCTTGCGGCACAACTCCGGCATTCTCTCCATGGAGACCTTCCGCGGCGTCATCGGC
CACGAGCGCCCCTTGCCGACTCTCGACTGTTCCACACCGGCCGCCGCAGGCGAGAATCCGCTCTGCGGCATCTTCGGGCA
CTTCCCGACTTTGGACGAAGTGGAGCAGTACATGATCGCCGAGGCGATGAAGCTGGCCAAAGGGAACCAGGGGTTAGCCG
GAAAGATCCTGGGCATGGGGCGCCAGACCCTGAACAAGCGGCTGAAGCTGCAGGCGTCGTAA

Upstream 100 bases:

>100_bases
GAGAGGTAGGGCTCGGGGCCTGCTTCTACTTCACCCTCCCCGATGAAAACACGAGGCACGGAGCAGACCACTGTTCGGCA
AGGCAGGAGGAGCGCAAAAA

Downstream 100 bases:

>100_bases
AAGGGGAAGTAAGGGTAAGTCCCCCCTCCCCTTGCGGGAGGGGGAGAGAAGGCGAACGAGCGGCTTCAGGAAGAGAAATG
CTCCGCCACCATCCCCTGCG

Product: sigma-54-dependent transcriptional response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MNKEMKYTQRILLIDDEAQILETCRSCLNNAGHADVVIENDSSKVMSLLSREEFAVIVLDLRMPNLSGFELLPQIISQHP
QIKVIVATANNDVETVVNCIKEGAFDYLVKPIDVKRLITSVRKALEMRSLANELTALKQYMFTDRLDHPEAFRSIVTGNK
AMRAIFQYLEVISGTRQAVTITGETGTGKELIARAIHNLSGCSGEYVALNVAGLDDNMFSDTLFGHRKGAFTGADQARDG
LITRASGGTLFLDEIGDLNEMSQIKLLRLLQEQEYYPVGSDFIKKSDARLVLATNRDLQELIKQGKFRNDLYYRLCGHRV
HLPPLRDRLDDIPLLLEHFLGSAADCLGKKKPTPPPELAVMLALYHFPGNIRELEALVFDAVLRHNSGILSMETFRGVIG
HERPLPTLDCSTPAAAGENPLCGIFGHFPTLDEVEQYMIAEAMKLAKGNQGLAGKILGMGRQTLNKRLKLQAS

Sequences:

>Translated_473_residues
MNKEMKYTQRILLIDDEAQILETCRSCLNNAGHADVVIENDSSKVMSLLSREEFAVIVLDLRMPNLSGFELLPQIISQHP
QIKVIVATANNDVETVVNCIKEGAFDYLVKPIDVKRLITSVRKALEMRSLANELTALKQYMFTDRLDHPEAFRSIVTGNK
AMRAIFQYLEVISGTRQAVTITGETGTGKELIARAIHNLSGCSGEYVALNVAGLDDNMFSDTLFGHRKGAFTGADQARDG
LITRASGGTLFLDEIGDLNEMSQIKLLRLLQEQEYYPVGSDFIKKSDARLVLATNRDLQELIKQGKFRNDLYYRLCGHRV
HLPPLRDRLDDIPLLLEHFLGSAADCLGKKKPTPPPELAVMLALYHFPGNIRELEALVFDAVLRHNSGILSMETFRGVIG
HERPLPTLDCSTPAAAGENPLCGIFGHFPTLDEVEQYMIAEAMKLAKGNQGLAGKILGMGRQTLNKRLKLQAS
>Mature_473_residues
MNKEMKYTQRILLIDDEAQILETCRSCLNNAGHADVVIENDSSKVMSLLSREEFAVIVLDLRMPNLSGFELLPQIISQHP
QIKVIVATANNDVETVVNCIKEGAFDYLVKPIDVKRLITSVRKALEMRSLANELTALKQYMFTDRLDHPEAFRSIVTGNK
AMRAIFQYLEVISGTRQAVTITGETGTGKELIARAIHNLSGCSGEYVALNVAGLDDNMFSDTLFGHRKGAFTGADQARDG
LITRASGGTLFLDEIGDLNEMSQIKLLRLLQEQEYYPVGSDFIKKSDARLVLATNRDLQELIKQGKFRNDLYYRLCGHRV
HLPPLRDRLDDIPLLLEHFLGSAADCLGKKKPTPPPELAVMLALYHFPGNIRELEALVFDAVLRHNSGILSMETFRGVIG
HERPLPTLDCSTPAAAGENPLCGIFGHFPTLDEVEQYMIAEAMKLAKGNQGLAGKILGMGRQTLNKRLKLQAS

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=460, Percent_Identity=37.3913043478261, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1788550, Length=466, Percent_Identity=35.8369098712446, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1790299, Length=469, Percent_Identity=35.181236673774, Blast_Score=265, Evalue=7e-72,
Organism=Escherichia coli, GI1788905, Length=404, Percent_Identity=34.1584158415842, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1789087, Length=334, Percent_Identity=40.1197604790419, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI87082117, Length=408, Percent_Identity=35.0490196078431, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1789233, Length=380, Percent_Identity=34.7368421052632, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI87082152, Length=226, Percent_Identity=42.4778761061947, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1787583, Length=329, Percent_Identity=33.1306990881459, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI87081872, Length=298, Percent_Identity=37.5838926174497, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789828, Length=240, Percent_Identity=38.75, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1786524, Length=332, Percent_Identity=34.9397590361446, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87081858, Length=395, Percent_Identity=25.0632911392405, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87082012, Length=133, Percent_Identity=32.3308270676692, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52505; Mature: 52505

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEMKYTQRILLIDDEAQILETCRSCLNNAGHADVVIENDSSKVMSLLSREEFAVIVLD
CCCCCCHHCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCEEEEEEE
LRMPNLSGFELLPQIISQHPQIKVIVATANNDVETVVNCIKEGAFDYLVKPIDVKRLITS
EECCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHCCCCCHHHHHHH
VRKALEMRSLANELTALKQYMFTDRLDHPEAFRSIVTGNKAMRAIFQYLEVISGTRQAVT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEE
ITGETGTGKELIARAIHNLSGCSGEYVALNVAGLDDNMFSDTLFGHRKGAFTGADQARDG
EECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHCC
LITRASGGTLFLDEIGDLNEMSQIKLLRLLQEQEYYPVGSDFIKKSDARLVLATNRDLQE
CEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCHHHHH
LIKQGKFRNDLYYRLCGHRVHLPPLRDRLDDIPLLLEHFLGSAADCLGKKKPTPPPELAV
HHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHH
MLALYHFPGNIRELEALVFDAVLRHNSGILSMETFRGVIGHERPLPTLDCSTPAAAGENP
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LCGIFGHFPTLDEVEQYMIAEAMKLAKGNQGLAGKILGMGRQTLNKRLKLQAS
CEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHEECCC
>Mature Secondary Structure
MNKEMKYTQRILLIDDEAQILETCRSCLNNAGHADVVIENDSSKVMSLLSREEFAVIVLD
CCCCCCHHCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCEEEEEEE
LRMPNLSGFELLPQIISQHPQIKVIVATANNDVETVVNCIKEGAFDYLVKPIDVKRLITS
EECCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHCCCCCHHHHHHH
VRKALEMRSLANELTALKQYMFTDRLDHPEAFRSIVTGNKAMRAIFQYLEVISGTRQAVT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEE
ITGETGTGKELIARAIHNLSGCSGEYVALNVAGLDDNMFSDTLFGHRKGAFTGADQARDG
EECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHCC
LITRASGGTLFLDEIGDLNEMSQIKLLRLLQEQEYYPVGSDFIKKSDARLVLATNRDLQE
CEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCHHHHH
LIKQGKFRNDLYYRLCGHRVHLPPLRDRLDDIPLLLEHFLGSAADCLGKKKPTPPPELAV
HHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHH
MLALYHFPGNIRELEALVFDAVLRHNSGILSMETFRGVIGHERPLPTLDCSTPAAAGENP
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LCGIFGHFPTLDEVEQYMIAEAMKLAKGNQGLAGKILGMGRQTLNKRLKLQAS
CEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7553451 [H]