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The map label for this gene is ycbL [H]

Identifier: 197118053

GI number: 197118053

Start: 1932671

End: 1933300

Strand: Direct

Name: ycbL [H]

Synonym: Gbem_1666

Alternate gene names: 197118053

Gene position: 1932671-1933300 (Clockwise)

Preceding gene: 197118052

Following gene: 197118054

Centisome position: 41.88

GC content: 62.86

Gene sequence:

>630_bases
ATGTTATTCGAGACCATAGTGGTTGGCGCCCTCGGGGTCAACTGCTTCATACTGGGAGACAAGCAGAGTAACGAAGGGGT
GGTGGTGGACCCGGGTGCAGACTTCGAGCTGATCGCCGACGCCATCGCGCGCTTCGGGATCAAGGTCAAGTACATCATCA
ACACCCACGGCCACTTCGACCACGTCGGCTGCAACCGTAGCGTCCAAGAGAAGACCGGCGCGGAGCTTTTGATCCACCAG
GGGGACCAAACGCTTCTGGAACTGGCCGCCAAAAGCGCGCAGAAGTACGGGCTTAAGGCCGAGGCCTCTCCTGCCCCGAC
ACGGTTTCTTGAGGACGGCATGAAGCTCGAATTCGGCAAGCGCACCATCGAGGTGCTGCACACGCCCGGGCACACCCAGG
GGGGGTGCTGCCTCCTTCTCGCCCACGAGAAGCTGGTGATCACCGGCGACACCCTTTTCGCCGACTCTGTCGGGCGCACC
GACCTCCCCGGCGGGTCGCACGAGCAGCTGATGGCCTCGATCAAGGCGAAGTTGATGCCGCTTCCCGACGACACCACCGT
CTGGCCCGGACACGGCCCCTCCAGCACCATCGGCCGCGAGAGGCGCAGCAATCCCTACATCAACGAATAG

Upstream 100 bases:

>100_bases
TTTCGCCGCGCTGAAAAACGGCAAGGAATAAGCATCCGCTGAGTTTGAAGCGGGTTCGGGGCGCAGCCAAAAAGCCCCGG
CCGCGCAAGGAGGAAATGCC

Downstream 100 bases:

>100_bases
GAGGAGGCGATGCTGAAAGGGAAGGAGATCGTTCTCGGGGTAACCGGCGGGATTGCGGTGTACAAGGCCGTCGAACTTTT
GCGCCTTTTGGTCAAGGCGG

Product: zinc-dependent hydrolase YcbL, metallo-beta-lactamase superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MLFETIVVGALGVNCFILGDKQSNEGVVVDPGADFELIADAIARFGIKVKYIINTHGHFDHVGCNRSVQEKTGAELLIHQ
GDQTLLELAAKSAQKYGLKAEASPAPTRFLEDGMKLEFGKRTIEVLHTPGHTQGGCCLLLAHEKLVITGDTLFADSVGRT
DLPGGSHEQLMASIKAKLMPLPDDTTVWPGHGPSSTIGRERRSNPYINE

Sequences:

>Translated_209_residues
MLFETIVVGALGVNCFILGDKQSNEGVVVDPGADFELIADAIARFGIKVKYIINTHGHFDHVGCNRSVQEKTGAELLIHQ
GDQTLLELAAKSAQKYGLKAEASPAPTRFLEDGMKLEFGKRTIEVLHTPGHTQGGCCLLLAHEKLVITGDTLFADSVGRT
DLPGGSHEQLMASIKAKLMPLPDDTTVWPGHGPSSTIGRERRSNPYINE
>Mature_209_residues
MLFETIVVGALGVNCFILGDKQSNEGVVVDPGADFELIADAIARFGIKVKYIINTHGHFDHVGCNRSVQEKTGAELLIHQ
GDQTLLELAAKSAQKYGLKAEASPAPTRFLEDGMKLEFGKRTIEVLHTPGHTQGGCCLLLAHEKLVITGDTLFADSVGRT
DLPGGSHEQLMASIKAKLMPLPDDTTVWPGHGPSSTIGRERRSNPYINE

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=215, Percent_Identity=27.906976744186, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI21703352, Length=181, Percent_Identity=29.8342541436464, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI116642887, Length=181, Percent_Identity=29.8342541436464, Blast_Score=71, Evalue=6e-13,
Organism=Escherichia coli, GI1787158, Length=210, Percent_Identity=37.6190476190476, Blast_Score=150, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17538952, Length=218, Percent_Identity=25.2293577981651, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320478, Length=194, Percent_Identity=26.2886597938144, Blast_Score=65, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221330176, Length=218, Percent_Identity=29.3577981651376, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667703, Length=195, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24667711, Length=195, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356335, Length=195, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 22557; Mature: 22557

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFETIVVGALGVNCFILGDKQSNEGVVVDPGADFELIADAIARFGIKVKYIINTHGHFD
CCHHHEEHEECCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCC
HVGCNRSVQEKTGAELLIHQGDQTLLELAAKSAQKYGLKAEASPAPTRFLEDGMKLEFGK
CCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCEEEECC
RTIEVLHTPGHTQGGCCLLLAHEKLVITGDTLFADSVGRTDLPGGSHEQLMASIKAKLMP
EEEEEEECCCCCCCCEEEEEECCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHEEC
LPDDTTVWPGHGPSSTIGRERRSNPYINE
CCCCCEECCCCCCCCCCCCHHCCCCCCCC
>Mature Secondary Structure
MLFETIVVGALGVNCFILGDKQSNEGVVVDPGADFELIADAIARFGIKVKYIINTHGHFD
CCHHHEEHEECCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCC
HVGCNRSVQEKTGAELLIHQGDQTLLELAAKSAQKYGLKAEASPAPTRFLEDGMKLEFGK
CCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCEEEECC
RTIEVLHTPGHTQGGCCLLLAHEKLVITGDTLFADSVGRTDLPGGSHEQLMASIKAKLMP
EEEEEEECCCCCCCCEEEEEECCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHEEC
LPDDTTVWPGHGPSSTIGRERRSNPYINE
CCCCCEECCCCCCCCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]