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The map label for this gene is apl-3 [H]

Identifier: 197117904

GI number: 197117904

Start: 1755549

End: 1757543

Strand: Reverse

Name: apl-3 [H]

Synonym: Gbem_1517

Alternate gene names: 197117904

Gene position: 1757543-1755549 (Counterclockwise)

Preceding gene: 197117905

Following gene: 197117903

Centisome position: 38.08

GC content: 64.06

Gene sequence:

>1995_bases
ATGACGATGAAAAAGATATTTATTGCAGCCACCCTGGCCCTCTCCGTTGCCGCTGCCGCCTTTGCCGAAGAGCAAAAGGC
AGCCCCGGCCGCAGCCCCCGCGGTGAGCGCACCCGCAGCTCAGGGCGCAGCCCCCGCGGTAGCAGCCCCCGCAGCCCAGG
TCAACCAGTCCCAGGCGGTTGCAACGCCCGCCCCGGCCAAGCCCGCTCCGGCCAAAAGGGAGTTAAAGACCAACAGGACC
ATCACCATCGGCATGTTCATGGTGATCATCGCCATCACCATGGGTGTGGTAGTCTGGGCTGCCAAGCAGACCAAGACAGC
TTCCGACTTCTACGCCGCAGGCGGCGGCATCACGGGGACCCAGAACGGCTGGGCCATCGCCGGCGACTACATGTCGGCAG
CCTCCTTCCTGGGGATTTCCGGCCTCATCTCGCTCTACGGCTATGACGGGTTCATGTACTCGGTCGGCTGGCTGGTGGCC
TACATCACGGTGCTCCTGATCGTGGCCGAACCGTGCCGCAACGCGGGCAAGTACACCCTGGGGGATATCCTCTCCTTCCG
TACTTCCCCGAAACCGGTGCGCGCCTTCGCCGCCCTCTCCACCGTCGCGGTCTCCACCTTCTACCTCACCGCCCAGATGG
TCGGTGCAGGCAAGCTGATGGCGCTTCTGGTCGGCATCCCCTATAAGATGTCCATCATTGGCGTCGGCATCCTCATGGTC
GGCTACGTCGTCTTCGGCGGCATGGTCGCCACCACCTGGGTACAGATCATCAAGGCAGGCCTCCTCATGTCGGGCGCCTT
CCTGCTCTCCTTCCTGGTCATGATCAAGGCAGGCTTCAACCCGATCGGCTTCTTCTCCACCATCGTCAACAGCCCCGACA
TCCAGGACCACGTCTCCAAGCTGGTATTGAAAGACGGCGTCATCCTTGCCGGCGCGGACGCAGGACAGCGCTTCCTTGAG
CCTGGCCTCTACATGAAGAACCCGCTGGACCAGATCTCCCTGGGGATGGCCCTCGTGCTCGGCACCGCCGGCATGCCGCA
CATCCTGATGCGCTTTTTCACCGTCCCGACCGCACAGGCGGCGCGTAAATCGGTCATCATCGCGATGTTCATCATCGGCG
GCTTCTACGTCCTGACCACCCTGCTCGGCTTCGGCGCAGCCATCCACCTCACCCCGCAGGGGATCACCCAGGTCGACCCG
GGCGGCAACATGGCTACCCTCATGCTGGCTCAGCAGATGGGCGCCGACATCGCACCCGTCTTCGGCGACCTCTTCCTCGC
CTTCCTGTGCGCCGTCGCCTTCGCCACCATCCTCGCCGTCGTCTCCGGCCTGGTGCTCGCGGCCTCCGCGGCCATCGCAC
ACGACATCTACGTCAACGTGATCAAAGACGGCCACGCCGACCAGCACGAGCAGGTCTTCGCGGCACGCGCCACCTCCTTC
GTGGTAGGCGCCTGCGGCATCATGATCGGCCTCGCGGCCGAGAAGCAGAACGTCGCTCACCTGGTGGCACTCGCCTTCGC
GGTCGCCGCTTCCGGCAACCTGCCGGTCGTCATCCTCTCGCTCTTCTGGAGGAAGTTCAACACCGCCGGCGTCATCTCCG
GCCTTTTGGTCGGCACCATCGCCTCCATCGCGCTGGTGATGGTCTCCCCCAACATGACCTACCCGAAAGTGGTGGCCGAA
GGCGCCAAGAAGGTGGTCGTCGCCATGGAGAAGAAGCAGGCCGCTCTGCCGGCAGGCGAGACCCTCTCCGAGAAAGACGC
CAAGGCGCTCGCCAAGGCGAAGGTGGACGCACAGCAGACCGGCACCTCCATGGTCGGCCTGGAGAAGCCGCTCTTCACTC
TGAAGAACCCGGGCATCGTCTCCATCCCGCTGGGCTTCATGGCCGCCATCCTCGGTTGCCTCGCCTTCCCGAACAGGCGT
TCCGAAGAGATGTTCGACGAGGTCTACGTACGCCAGAACACCGGTTTGGGTATGGCCAAGGCAGTCGAACACTAG

Upstream 100 bases:

>100_bases
GGAATCGCGCTCTACTACTCGCACGTCGCCAACAAGGACTTTGACCGGTTGACCAGGGAACTGATCGACGAACTGCATCT
CTAGGAAAGGAGGAACGACA

Downstream 100 bases:

>100_bases
CAGCAAACGTATAGGGTTGAATCGACTGGGGGAGGGAAACCTTCCCCAGTTTTTTTGTTTCTGAGGCGGCAAAAAAGGAC
TGTAACGAGGCCCAAAACCC

Product: sodium/solute symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MTMKKIFIAATLALSVAAAAFAEEQKAAPAAAPAVSAPAAQGAAPAVAAPAAQVNQSQAVATPAPAKPAPAKRELKTNRT
ITIGMFMVIIAITMGVVVWAAKQTKTASDFYAAGGGITGTQNGWAIAGDYMSAASFLGISGLISLYGYDGFMYSVGWLVA
YITVLLIVAEPCRNAGKYTLGDILSFRTSPKPVRAFAALSTVAVSTFYLTAQMVGAGKLMALLVGIPYKMSIIGVGILMV
GYVVFGGMVATTWVQIIKAGLLMSGAFLLSFLVMIKAGFNPIGFFSTIVNSPDIQDHVSKLVLKDGVILAGADAGQRFLE
PGLYMKNPLDQISLGMALVLGTAGMPHILMRFFTVPTAQAARKSVIIAMFIIGGFYVLTTLLGFGAAIHLTPQGITQVDP
GGNMATLMLAQQMGADIAPVFGDLFLAFLCAVAFATILAVVSGLVLAASAAIAHDIYVNVIKDGHADQHEQVFAARATSF
VVGACGIMIGLAAEKQNVAHLVALAFAVAASGNLPVVILSLFWRKFNTAGVISGLLVGTIASIALVMVSPNMTYPKVVAE
GAKKVVVAMEKKQAALPAGETLSEKDAKALAKAKVDAQQTGTSMVGLEKPLFTLKNPGIVSIPLGFMAAILGCLAFPNRR
SEEMFDEVYVRQNTGLGMAKAVEH

Sequences:

>Translated_664_residues
MTMKKIFIAATLALSVAAAAFAEEQKAAPAAAPAVSAPAAQGAAPAVAAPAAQVNQSQAVATPAPAKPAPAKRELKTNRT
ITIGMFMVIIAITMGVVVWAAKQTKTASDFYAAGGGITGTQNGWAIAGDYMSAASFLGISGLISLYGYDGFMYSVGWLVA
YITVLLIVAEPCRNAGKYTLGDILSFRTSPKPVRAFAALSTVAVSTFYLTAQMVGAGKLMALLVGIPYKMSIIGVGILMV
GYVVFGGMVATTWVQIIKAGLLMSGAFLLSFLVMIKAGFNPIGFFSTIVNSPDIQDHVSKLVLKDGVILAGADAGQRFLE
PGLYMKNPLDQISLGMALVLGTAGMPHILMRFFTVPTAQAARKSVIIAMFIIGGFYVLTTLLGFGAAIHLTPQGITQVDP
GGNMATLMLAQQMGADIAPVFGDLFLAFLCAVAFATILAVVSGLVLAASAAIAHDIYVNVIKDGHADQHEQVFAARATSF
VVGACGIMIGLAAEKQNVAHLVALAFAVAASGNLPVVILSLFWRKFNTAGVISGLLVGTIASIALVMVSPNMTYPKVVAE
GAKKVVVAMEKKQAALPAGETLSEKDAKALAKAKVDAQQTGTSMVGLEKPLFTLKNPGIVSIPLGFMAAILGCLAFPNRR
SEEMFDEVYVRQNTGLGMAKAVEH
>Mature_663_residues
TMKKIFIAATLALSVAAAAFAEEQKAAPAAAPAVSAPAAQGAAPAVAAPAAQVNQSQAVATPAPAKPAPAKRELKTNRTI
TIGMFMVIIAITMGVVVWAAKQTKTASDFYAAGGGITGTQNGWAIAGDYMSAASFLGISGLISLYGYDGFMYSVGWLVAY
ITVLLIVAEPCRNAGKYTLGDILSFRTSPKPVRAFAALSTVAVSTFYLTAQMVGAGKLMALLVGIPYKMSIIGVGILMVG
YVVFGGMVATTWVQIIKAGLLMSGAFLLSFLVMIKAGFNPIGFFSTIVNSPDIQDHVSKLVLKDGVILAGADAGQRFLEP
GLYMKNPLDQISLGMALVLGTAGMPHILMRFFTVPTAQAARKSVIIAMFIIGGFYVLTTLLGFGAAIHLTPQGITQVDPG
GNMATLMLAQQMGADIAPVFGDLFLAFLCAVAFATILAVVSGLVLAASAAIAHDIYVNVIKDGHADQHEQVFAARATSFV
VGACGIMIGLAAEKQNVAHLVALAFAVAASGNLPVVILSLFWRKFNTAGVISGLLVGTIASIALVMVSPNMTYPKVVAEG
AKKVVVAMEKKQAALPAGETLSEKDAKALAKAKVDAQQTGTSMVGLEKPLFTLKNPGIVSIPLGFMAAILGCLAFPNRRS
EEMFDEVYVRQNTGLGMAKAVEH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI1790503, Length=616, Percent_Identity=38.7987012987013, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI87082237, Length=474, Percent_Identity=23.4177215189873, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787251, Length=462, Percent_Identity=22.7272727272727, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 68994; Mature: 68862

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMKKIFIAATLALSVAAAAFAEEQKAAPAAAPAVSAPAAQGAAPAVAAPAAQVNQSQAV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCHHHCCCCCCC
ATPAPAKPAPAKRELKTNRTITIGMFMVIIAITMGVVVWAAKQTKTASDFYAAGGGITGT
CCCCCCCCCCCHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCC
QNGWAIAGDYMSAASFLGISGLISLYGYDGFMYSVGWLVAYITVLLIVAEPCRNAGKYTL
CCCCEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
GDILSFRTSPKPVRAFAALSTVAVSTFYLTAQMVGAGKLMALLVGIPYKMSIIGVGILMV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
GYVVFGGMVATTWVQIIKAGLLMSGAFLLSFLVMIKAGFNPIGFFSTIVNSPDIQDHVSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHH
LVLKDGVILAGADAGQRFLEPGLYMKNPLDQISLGMALVLGTAGMPHILMRFFTVPTAQA
HHHHCCCEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
ARKSVIIAMFIIGGFYVLTTLLGFGAAIHLTPQGITQVDPGGNMATLMLAQQMGADIAPV
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEECCCCCHHHHHHHHHHCCCHHHH
FGDLFLAFLCAVAFATILAVVSGLVLAASAAIAHDIYVNVIKDGHADQHEQVFAARATSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHH
VVGACGIMIGLAAEKQNVAHLVALAFAVAASGNLPVVILSLFWRKFNTAGVISGLLVGTI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHH
ASIALVMVSPNMTYPKVVAEGAKKVVVAMEKKQAALPAGETLSEKDAKALAKAKVDAQQT
HHHHHHEECCCCCCHHHHHHCHHHEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHC
GTSMVGLEKPLFTLKNPGIVSIPLGFMAAILGCLAFPNRRSEEMFDEVYVRQNTGLGMAK
CCCHHCCCCCCCEECCCCEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHH
AVEH
HCCC
>Mature Secondary Structure 
TMKKIFIAATLALSVAAAAFAEEQKAAPAAAPAVSAPAAQGAAPAVAAPAAQVNQSQAV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCHHHCCCCCCC
ATPAPAKPAPAKRELKTNRTITIGMFMVIIAITMGVVVWAAKQTKTASDFYAAGGGITGT
CCCCCCCCCCCHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCC
QNGWAIAGDYMSAASFLGISGLISLYGYDGFMYSVGWLVAYITVLLIVAEPCRNAGKYTL
CCCCEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
GDILSFRTSPKPVRAFAALSTVAVSTFYLTAQMVGAGKLMALLVGIPYKMSIIGVGILMV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
GYVVFGGMVATTWVQIIKAGLLMSGAFLLSFLVMIKAGFNPIGFFSTIVNSPDIQDHVSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHH
LVLKDGVILAGADAGQRFLEPGLYMKNPLDQISLGMALVLGTAGMPHILMRFFTVPTAQA
HHHHCCCEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
ARKSVIIAMFIIGGFYVLTTLLGFGAAIHLTPQGITQVDPGGNMATLMLAQQMGADIAPV
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEECCCCCHHHHHHHHHHCCCHHHH
FGDLFLAFLCAVAFATILAVVSGLVLAASAAIAHDIYVNVIKDGHADQHEQVFAARATSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHH
VVGACGIMIGLAAEKQNVAHLVALAFAVAASGNLPVVILSLFWRKFNTAGVISGLLVGTI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHH
ASIALVMVSPNMTYPKVVAEGAKKVVVAMEKKQAALPAGETLSEKDAKALAKAKVDAQQT
HHHHHHEECCCCCCHHHHHHCHHHEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHC
GTSMVGLEKPLFTLKNPGIVSIPLGFMAAILGCLAFPNRRSEEMFDEVYVRQNTGLGMAK
CCCHHCCCCCCCEECCCCEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHH
AVEH
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]