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The map label for this gene is bamQ [C]

Identifier: 197117818

GI number: 197117818

Start: 1653545

End: 1654618

Strand: Direct

Name: bamQ [C]

Synonym: Gbem_1431

Alternate gene names: 197117818

Gene position: 1653545-1654618 (Clockwise)

Preceding gene: 197117817

Following gene: 197117819

Centisome position: 35.83

GC content: 65.74

Gene sequence:

>1074_bases
ATGTCCAAGTCAGCGTATCGCTGGTCCATGACCGCCGTCGGTGAACCGATGCAAAAGGGTGAATTCGCCCCTGCGCCGGG
CGCGGGAGAAGTCGTCGTCGAGGTCGCCGGCTGCGGCGTCTGCCACACCGACCTTGGTTTCTATTACAGCGGCGTCCGCT
TCAACCACCCCGCACCGCTCACGCTGGGGCACGAGATCAGCGGCCGCGTGGTCACGGCGGGCGAGGGGGCTGGCCAGTGG
GTTGGCAAGGCGGTGCTCATTCCGGCGGTCATCCCCTGCGGCGAATGCGACCTCTGCCTCTCCAGTCACGGCACCATCTG
CCGCGCGCAGCAGATGCCCGGCAACGACATCCACGGCGGCTTCGCCTCCCACATCGTGGTTCCGGCTAAGACCCTCTGCC
CGGTCGACGAGAAGCGCCTCGCCGCGGCAGGGCTTGAGCTTGCCGACATCTCGGTCGTGGCCGACGCGGTGACCACACCT
TACCAGGCAGCGGTGCAGGCCGAGGTCCAGCCCGGCGACGTCGCCATCGTGATCGGCGTGGGCGGGGTAGGCGGCTACGC
GGTGCAGGTGGCCAACGCTCTCGGCGCAACCGTCATCGCCATCGACGTGGACCCGGTGAAGCTGGAAAACGTTGGCAAGC
ACGGCGCGGCGCTCACCCTCAACTCCCGCGAGATCGCCGGCAAGGAACTGAAGAAGGCGATAAACGACTTCGTGAAGGCG
AAGGGGCTGAAGCAGACCTGCTGGAAGATATTCGAATGCTCCGGCAGCACCCCCGGCCAGGAGACCGCCTTCAGCCTCCT
CACCTACGGGGCCACCCTCTCCGTCGTCGGCTTCACCATGGACAAGATCGAGCTGCGCCTCTCAAACCTGATGGCGTTCC
ACGCCAGGGCCCTTGGGAACTGGGGCTGTCTGACCGAACTGTATCCGGCCGCGCTCGACCTCGTGCTCGACGGAAAGGTC
GCCCTGACGCCGTTCATCGAGAAGCATCCCCTGGACAACATCAACCAGGTGTTTGCCTCCGCACATGCCCACAAGCTCAC
CAGGCGCGCCATCTTAGTGCCGGGTCTTTCCTAG

Upstream 100 bases:

>100_bases
CTTGACAGCTAAATAAGCATTGTGGTACTTATTTACCATAACAGGATTTGCCACCGAAAACGATTCGATAAAAAACCACT
TTAAGCAAGGAGGAAGCTTT

Downstream 100 bases:

>100_bases
GAGGACGCCATGAGCCAAGCCGCTACCCAAGCACCGCAAACCGCCGCAGCCGACTCGCCGCTCAAGGTGTCTCTTGAGCG
CGACGGCCGCCTTTTGAAAC

Product: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase

Products: NA

Alternate protein names: ADH-HT [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSKSAYRWSMTAVGEPMQKGEFAPAPGAGEVVVEVAGCGVCHTDLGFYYSGVRFNHPAPLTLGHEISGRVVTAGEGAGQW
VGKAVLIPAVIPCGECDLCLSSHGTICRAQQMPGNDIHGGFASHIVVPAKTLCPVDEKRLAAAGLELADISVVADAVTTP
YQAAVQAEVQPGDVAIVIGVGGVGGYAVQVANALGATVIAIDVDPVKLENVGKHGAALTLNSREIAGKELKKAINDFVKA
KGLKQTCWKIFECSGSTPGQETAFSLLTYGATLSVVGFTMDKIELRLSNLMAFHARALGNWGCLTELYPAALDLVLDGKV
ALTPFIEKHPLDNINQVFASAHAHKLTRRAILVPGLS

Sequences:

>Translated_357_residues
MSKSAYRWSMTAVGEPMQKGEFAPAPGAGEVVVEVAGCGVCHTDLGFYYSGVRFNHPAPLTLGHEISGRVVTAGEGAGQW
VGKAVLIPAVIPCGECDLCLSSHGTICRAQQMPGNDIHGGFASHIVVPAKTLCPVDEKRLAAAGLELADISVVADAVTTP
YQAAVQAEVQPGDVAIVIGVGGVGGYAVQVANALGATVIAIDVDPVKLENVGKHGAALTLNSREIAGKELKKAINDFVKA
KGLKQTCWKIFECSGSTPGQETAFSLLTYGATLSVVGFTMDKIELRLSNLMAFHARALGNWGCLTELYPAALDLVLDGKV
ALTPFIEKHPLDNINQVFASAHAHKLTRRAILVPGLS
>Mature_356_residues
SKSAYRWSMTAVGEPMQKGEFAPAPGAGEVVVEVAGCGVCHTDLGFYYSGVRFNHPAPLTLGHEISGRVVTAGEGAGQWV
GKAVLIPAVIPCGECDLCLSSHGTICRAQQMPGNDIHGGFASHIVVPAKTLCPVDEKRLAAAGLELADISVVADAVTTPY
QAAVQAEVQPGDVAIVIGVGGVGGYAVQVANALGATVIAIDVDPVKLENVGKHGAALTLNSREIAGKELKKAINDFVKAK
GLKQTCWKIFECSGSTPGQETAFSLLTYGATLSVVGFTMDKIELRLSNLMAFHARALGNWGCLTELYPAALDLVLDGKVA
LTPFIEKHPLDNINQVFASAHAHKLTRRAILVPGLS

Specific function: Thermophilic NAD(+)-dependent alcohol dehydrogenase. Bears mainly an ethanol-dehydrogenase activity [H]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71565154, Length=378, Percent_Identity=25.9259259259259, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI156523966, Length=378, Percent_Identity=26.984126984127, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI4501939, Length=345, Percent_Identity=27.2463768115942, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI34577061, Length=263, Percent_Identity=30.4182509505703, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4501929, Length=382, Percent_Identity=26.1780104712042, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4501933, Length=261, Percent_Identity=28.735632183908, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1788407, Length=339, Percent_Identity=26.5486725663717, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081918, Length=328, Percent_Identity=25.9146341463415, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786552, Length=366, Percent_Identity=29.5081967213115, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI226510992, Length=323, Percent_Identity=25.6965944272446, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082125, Length=302, Percent_Identity=25.8278145695364, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790045, Length=306, Percent_Identity=24.5098039215686, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787863, Length=267, Percent_Identity=26.9662921348315, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788075, Length=319, Percent_Identity=25.0783699059561, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788073, Length=263, Percent_Identity=27.3764258555133, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082401, Length=337, Percent_Identity=25.5192878338279, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790718, Length=323, Percent_Identity=23.2198142414861, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786518, Length=222, Percent_Identity=30.6306306306306, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=327, Percent_Identity=27.217125382263, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562878, Length=320, Percent_Identity=27.8125, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=183, Percent_Identity=28.4153005464481, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562584, Length=194, Percent_Identity=29.3814432989691, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562582, Length=183, Percent_Identity=29.5081967213115, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323729, Length=201, Percent_Identity=30.8457711442786, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320033, Length=362, Percent_Identity=27.9005524861878, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322619, Length=336, Percent_Identity=25.297619047619, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319955, Length=336, Percent_Identity=25.297619047619, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323099, Length=341, Percent_Identity=25.5131964809384, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=189, Percent_Identity=30.6878306878307, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=182, Percent_Identity=31.3186813186813, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319258, Length=323, Percent_Identity=22.9102167182663, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319621, Length=182, Percent_Identity=30.7692307692308, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17737895, Length=365, Percent_Identity=27.1232876712329, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 37289; Mature: 37158

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00059 ADH_ZINC ; PS00222 IGF_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSAYRWSMTAVGEPMQKGEFAPAPGAGEVVVEVAGCGVCHTDLGFYYSGVRFNHPAPL
CCCCCEEEEEHHCCCCHHCCCCCCCCCCCCEEEEEECCCEEECCCCCEECCEEECCCCCE
TLGHEISGRVVTAGEGAGQWVGKAVLIPAVIPCGECDLCLSSHGTICRAQQMPGNDIHGG
EECCCCCCEEEECCCCCCHHHCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCC
FASHIVVPAKTLCPVDEKRLAAAGLELADISVVADAVTTPYQAAVQAEVQPGDVAIVIGV
HHCEEEECHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCEEEEEEE
GGVGGYAVQVANALGATVIAIDVDPVKLENVGKHGAALTLNSREIAGKELKKAINDFVKA
CCCCHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
KGLKQTCWKIFECSGSTPGQETAFSLLTYGATLSVVGFTMDKIELRLSNLMAFHARALGN
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCC
WGCLTELYPAALDLVLDGKVALTPFIEKHPLDNINQVFASAHAHKLTRRAILVPGLS
CCCHHHHHHHHHEEEECCCEEECCCHHHCCCCHHHHHHHHHHHHHHHHCEEECCCCC
>Mature Secondary Structure 
SKSAYRWSMTAVGEPMQKGEFAPAPGAGEVVVEVAGCGVCHTDLGFYYSGVRFNHPAPL
CCCCEEEEEHHCCCCHHCCCCCCCCCCCCEEEEEECCCEEECCCCCEECCEEECCCCCE
TLGHEISGRVVTAGEGAGQWVGKAVLIPAVIPCGECDLCLSSHGTICRAQQMPGNDIHGG
EECCCCCCEEEECCCCCCHHHCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCC
FASHIVVPAKTLCPVDEKRLAAAGLELADISVVADAVTTPYQAAVQAEVQPGDVAIVIGV
HHCEEEECHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCEEEEEEE
GGVGGYAVQVANALGATVIAIDVDPVKLENVGKHGAALTLNSREIAGKELKKAINDFVKA
CCCCHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
KGLKQTCWKIFECSGSTPGQETAFSLLTYGATLSVVGFTMDKIELRLSNLMAFHARALGN
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCC
WGCLTELYPAALDLVLDGKVALTPFIEKHPLDNINQVFASAHAHKLTRRAILVPGLS
CCCHHHHHHHHHEEEECCCEEECCCHHHCCCCHHHHHHHHHHHHHHHHCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020473 [H]