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The map label for this gene is cat2 [H]

Identifier: 197117817

GI number: 197117817

Start: 1651375

End: 1653225

Strand: Direct

Name: cat2 [H]

Synonym: Gbem_1430

Alternate gene names: 197117817

Gene position: 1651375-1653225 (Clockwise)

Preceding gene: 197117814

Following gene: 197117818

Centisome position: 35.78

GC content: 63.8

Gene sequence:

>1851_bases
ATGAACGAAGAACTAAAGCAGTTGTATCGGGACCGGCTGACCACCGCGGACGAGGCGGTACGTCATCTCCAGTCGGGGTG
GCGCGTTTTTCTCGGGTCGGGGTGCGCGGTACCGGGGGAGCTCGTCGCCGCGCTGGCGCGGCAGGCCGACCGGTTCCACG
ACGTGGAACTGATCCAGCTCCTCACCTTTGGCACTGGGCAATACCTGAACGGCAAGGATGCCGGAAGGCTGCGGCACAAC
TCCTTTTTCATCAGTGAAAATATCCGTCAGGCGGTGTGCGACGGCCGGGCCGACTACACCCCCATCTTCCTGAGTGAGAT
CCCGGAACTGATCCGGTCGGGCCAGAGGGGGAACCAGGCTGCGCTGTTGCAGGTGTCGCCCCCGGACCGACACGGTTACT
GCAGCATGGGGGTGAACGTGGACATCCAGCGGGCCGCGCTCGACCGGGCGAAGCTGGTGATCGCCGAGGTGAACCCGCGG
ATGCCGCGCACCTGCGGTGACAGCTACGTACACCTAAGCCGCCTGGACCTTCTGGTGGAGACGGACCATCCGATTCTTGT
CTCCGAGGCGAAGGCCCCCGACGAGGTGGAGCAGCAGATCGGGTACCACATCTCGCGGCTGGTGGAAAACGGGAGCTGCC
TGCAGCTGGGGATCGGCACCATACCGAGCACCGTGCTGCAGTTCATAGCGGACAAACGCGATCTGGGGGTCCACAGCGAG
ATGTTCAGCGACGCCTTGATCCCGCTCATCGAAGAGGGGAACGTCACCAACCGTCTGAAGCGGGTGCATCCGGGGAAGAC
GGTGGCGAGTTTCGTCATCGGCAGCCGCAAGCTGTACGACTTCGTCGACGGCAACGTCGGCGTCGAGTTCCATCCATCCG
ATTTCGTCAACGACCCCAGGGTCATCTCCATGAACGACAAGGTGGTGGCGATAAACTCGGCGCTGCAGGTCGACCTGACC
GGGCAGATATGCGCCGACAGCATCGGATACCAGTTCTACAGCGGCATCGGCGGCCAGGTGGACTTCGCGCGCGGCGCGGC
CATGAGCCGGGGGGGGAAGCCGATCATCGCCGTTCGCAGCACCGCCCGGGACGGGAGCATCAGCCGCATCGTGCATCGGA
TCGACGACGGCGCGGGCGTGGTCACCAGCCGCGGCGACGCCCACTACGTGGTTTCCGAGTACGGCATCGCCTACCTGCAC
GGGAAGACCATAAGAGAACGCGCCTTGGCGCTTATCTCCATAGCCCATCCGGAGTACCGCCGGGAGTTGCTCGATTTCGT
CAAGAAGAAGCACTACGTTTACGAGGACGAGCAGGTGTGGCGGCAGGCGCTGGACAAGTACCCGGCGAACCTGGAGGAGG
ATAGATCCTTCGGAGGAATGACGATGCAGGTGAGGCCCCTGAAGGCGACCGACGAGCGGACGCTGCAGGAGTTCTTCTAC
AGCCTCGACGCGGAGACGGTCTACCACCGCTTCTTCGGTCCGAAGCTGCAGATGGCGCACCTTGAAGCGGCAAAGCAAGT
CTGCGTCGACTATAGCGGCCGCATGGCGCTGGCCGCCTTTCGCCACGAGGACCAGGCCGAATGCATGGTGGCGGTGGCTC
GCTACGAGGTCAACCCCCGGAGCAACATGGCGGAGACGGCGGTGGTGGTGCACCAGGATTACCGCAGGAAAGGGCTCGCC
GGCTACCTGCTGCGCCAGCTGGAGCGCCACGCCAAAGAGCAGGGAATCGAGGGCTTCTGCGCCGAGATCCTCCCGGAAAA
CGCCGCGATGCTCCGTTACCACAGAGGCCTCGGGCACACCCTGGTGCACTCCCCGGAGACCGAGACCTATCATGTGGAAT
ACCGGTTCTAA

Upstream 100 bases:

>100_bases
CTAATGTTGTTGGGGAAACTTCGTGTAACGTTTTGAGGGTCCGTGTAAAAAACTGAGGGCGCGGCGGGATGCTGGGAAAC
GGCGGGAGAGGGGGCAGGCG

Downstream 100 bases:

>100_bases
CCACCTACCCCCACCCCCTAGCCCCCTCCCGCAAGGGGAGGGGGATTGAACCAGGAGGAGCTGCCTGTCTCCCCTCGCCC
TCTGGGAGAGGGGCGGGGGT

Product: acyl-CoA--carboxylate CoA transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MNEELKQLYRDRLTTADEAVRHLQSGWRVFLGSGCAVPGELVAALARQADRFHDVELIQLLTFGTGQYLNGKDAGRLRHN
SFFISENIRQAVCDGRADYTPIFLSEIPELIRSGQRGNQAALLQVSPPDRHGYCSMGVNVDIQRAALDRAKLVIAEVNPR
MPRTCGDSYVHLSRLDLLVETDHPILVSEAKAPDEVEQQIGYHISRLVENGSCLQLGIGTIPSTVLQFIADKRDLGVHSE
MFSDALIPLIEEGNVTNRLKRVHPGKTVASFVIGSRKLYDFVDGNVGVEFHPSDFVNDPRVISMNDKVVAINSALQVDLT
GQICADSIGYQFYSGIGGQVDFARGAAMSRGGKPIIAVRSTARDGSISRIVHRIDDGAGVVTSRGDAHYVVSEYGIAYLH
GKTIRERALALISIAHPEYRRELLDFVKKKHYVYEDEQVWRQALDKYPANLEEDRSFGGMTMQVRPLKATDERTLQEFFY
SLDAETVYHRFFGPKLQMAHLEAAKQVCVDYSGRMALAAFRHEDQAECMVAVARYEVNPRSNMAETAVVVHQDYRRKGLA
GYLLRQLERHAKEQGIEGFCAEILPENAAMLRYHRGLGHTLVHSPETETYHVEYRF

Sequences:

>Translated_616_residues
MNEELKQLYRDRLTTADEAVRHLQSGWRVFLGSGCAVPGELVAALARQADRFHDVELIQLLTFGTGQYLNGKDAGRLRHN
SFFISENIRQAVCDGRADYTPIFLSEIPELIRSGQRGNQAALLQVSPPDRHGYCSMGVNVDIQRAALDRAKLVIAEVNPR
MPRTCGDSYVHLSRLDLLVETDHPILVSEAKAPDEVEQQIGYHISRLVENGSCLQLGIGTIPSTVLQFIADKRDLGVHSE
MFSDALIPLIEEGNVTNRLKRVHPGKTVASFVIGSRKLYDFVDGNVGVEFHPSDFVNDPRVISMNDKVVAINSALQVDLT
GQICADSIGYQFYSGIGGQVDFARGAAMSRGGKPIIAVRSTARDGSISRIVHRIDDGAGVVTSRGDAHYVVSEYGIAYLH
GKTIRERALALISIAHPEYRRELLDFVKKKHYVYEDEQVWRQALDKYPANLEEDRSFGGMTMQVRPLKATDERTLQEFFY
SLDAETVYHRFFGPKLQMAHLEAAKQVCVDYSGRMALAAFRHEDQAECMVAVARYEVNPRSNMAETAVVVHQDYRRKGLA
GYLLRQLERHAKEQGIEGFCAEILPENAAMLRYHRGLGHTLVHSPETETYHVEYRF
>Mature_616_residues
MNEELKQLYRDRLTTADEAVRHLQSGWRVFLGSGCAVPGELVAALARQADRFHDVELIQLLTFGTGQYLNGKDAGRLRHN
SFFISENIRQAVCDGRADYTPIFLSEIPELIRSGQRGNQAALLQVSPPDRHGYCSMGVNVDIQRAALDRAKLVIAEVNPR
MPRTCGDSYVHLSRLDLLVETDHPILVSEAKAPDEVEQQIGYHISRLVENGSCLQLGIGTIPSTVLQFIADKRDLGVHSE
MFSDALIPLIEEGNVTNRLKRVHPGKTVASFVIGSRKLYDFVDGNVGVEFHPSDFVNDPRVISMNDKVVAINSALQVDLT
GQICADSIGYQFYSGIGGQVDFARGAAMSRGGKPIIAVRSTARDGSISRIVHRIDDGAGVVTSRGDAHYVVSEYGIAYLH
GKTIRERALALISIAHPEYRRELLDFVKKKHYVYEDEQVWRQALDKYPANLEEDRSFGGMTMQVRPLKATDERTLQEFFY
SLDAETVYHRFFGPKLQMAHLEAAKQVCVDYSGRMALAAFRHEDQAECMVAVARYEVNPRSNMAETAVVVHQDYRRKGLA
GYLLRQLERHAKEQGIEGFCAEILPENAAMLRYHRGLGHTLVHSPETETYHVEYRF

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=470, Percent_Identity=25.9574468085106, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788938, Length=166, Percent_Identity=30.7228915662651, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI32563853, Length=419, Percent_Identity=46.0620525059666, Blast_Score=355, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI17538151, Length=427, Percent_Identity=43.559718969555, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI21358615, Length=416, Percent_Identity=45.6730769230769, Blast_Score=369, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 69018; Mature: 69018

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEELKQLYRDRLTTADEAVRHLQSGWRVFLGSGCAVPGELVAALARQADRFHDVELIQL
CCHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHH
LTFGTGQYLNGKDAGRLRHNSFFISENIRQAVCDGRADYTPIFLSEIPELIRSGQRGNQA
HHCCCCCCCCCCCCCCEECCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCE
ALLQVSPPDRHGYCSMGVNVDIQRAALDRAKLVIAEVNPRMPRTCGDSYVHLSRLDLLVE
EEEEECCCCCCCEEEECCCEEHHHHHHCHHEEEEEECCCCCCCCCCCCEEEHHHEEEEEE
TDHPILVSEAKAPDEVEQQIGYHISRLVENGSCLQLGIGTIPSTVLQFIADKRDLGVHSE
CCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCHHH
MFSDALIPLIEEGNVTNRLKRVHPGKTVASFVIGSRKLYDFVDGNVGVEFHPSDFVNDPR
HHHHHHCHHCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCCCCEEECCHHCCCCCE
VISMNDKVVAINSALQVDLTGQICADSIGYQFYSGIGGQVDFARGAAMSRGGKPIIAVRS
EEEECCCEEEECCEEEEEECCHHHHHHHCHHHHHCCCCCEEHHCCHHHCCCCCEEEEEEC
TARDGSISRIVHRIDDGAGVVTSRGDAHYVVSEYGIAYLHGKTIRERALALISIAHPEYR
CCCCCHHHHHHHHHCCCCCEEECCCCCEEEHHHCCEEEEECCHHHHHHHHHHHCCCHHHH
RELLDFVKKKHYVYEDEQVWRQALDKYPANLEEDRSFGGMTMQVRPLKATDERTLQEFFY
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
SLDAETVYHRFFGPKLQMAHLEAAKQVCVDYSGRMALAAFRHEDQAECMVAVARYEVNPR
HCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHEECCCC
SNMAETAVVVHQDYRRKGLAGYLLRQLERHAKEQGIEGFCAEILPENAAMLRYHRGLGHT
CCHHHHHEEEEHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCC
LVHSPETETYHVEYRF
EECCCCCCEEEEEEEC
>Mature Secondary Structure
MNEELKQLYRDRLTTADEAVRHLQSGWRVFLGSGCAVPGELVAALARQADRFHDVELIQL
CCHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHH
LTFGTGQYLNGKDAGRLRHNSFFISENIRQAVCDGRADYTPIFLSEIPELIRSGQRGNQA
HHCCCCCCCCCCCCCCEECCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCE
ALLQVSPPDRHGYCSMGVNVDIQRAALDRAKLVIAEVNPRMPRTCGDSYVHLSRLDLLVE
EEEEECCCCCCCEEEECCCEEHHHHHHCHHEEEEEECCCCCCCCCCCCEEEHHHEEEEEE
TDHPILVSEAKAPDEVEQQIGYHISRLVENGSCLQLGIGTIPSTVLQFIADKRDLGVHSE
CCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCHHH
MFSDALIPLIEEGNVTNRLKRVHPGKTVASFVIGSRKLYDFVDGNVGVEFHPSDFVNDPR
HHHHHHCHHCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCCCCEEECCHHCCCCCE
VISMNDKVVAINSALQVDLTGQICADSIGYQFYSGIGGQVDFARGAAMSRGGKPIIAVRS
EEEECCCEEEECCEEEEEECCHHHHHHHCHHHHHCCCCCEEHHCCHHHCCCCCEEEEEEC
TARDGSISRIVHRIDDGAGVVTSRGDAHYVVSEYGIAYLHGKTIRERALALISIAHPEYR
CCCCCHHHHHHHHHCCCCCEEECCCCCEEEHHHCCEEEEECCHHHHHHHHHHHCCCHHHH
RELLDFVKKKHYVYEDEQVWRQALDKYPANLEEDRSFGGMTMQVRPLKATDERTLQEFFY
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
SLDAETVYHRFFGPKLQMAHLEAAKQVCVDYSGRMALAAFRHEDQAECMVAVARYEVNPR
HCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHEECCCC
SNMAETAVVVHQDYRRKGLAGYLLRQLERHAKEQGIEGFCAEILPENAAMLRYHRGLGHT
CCHHHHHEEEEHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCC
LVHSPETETYHVEYRF
EECCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]